Gene

KWMTBOMO11202  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012665

Annotation

PREDICTED:_F-actin-capping_protein_subunit_alpha_[Papilio_machaon]

Location

Bomo_Chr19(+):430458-431558      View in EpiBrowser

Full name

F-actin-capping protein subunit alpha      

Location in the cell

Cytoplasmic   Reliability : 2.393

CDS

ATGGCGGCGGACGGTGACGAAGTGATTAGTGATCAAGAAAAAGTTAGAATCGTTTCAGATTTCATTTTGCATTCGCCGCCAGGGGAATTTAACGAAGTTTTCAATGATGTGAGGGTGTTGCTGAATAACGATACCTTGCTCAAGGAAGGTGCTAGTGGAGCCTTCGCTCAATACAACAAGGATCAACTCACGCCCGTACGTCTCGAAGGCTCCGAGCTGTATACACTCATCACCGACCACAACGAACTTGGTGGCGGAAGGTTTTTCGATCCTCGCTCCAAGTGTTCTTTCAGGTATGACCATCTACGCAAAGAAGCGTCCGAGTATGAACCCTACGAGCCCGATCGAGCGGCTGAGCCTTGGCGGGCGGCACTTGATGAGGAGCTAACGGCGTACGTGGCTGCACACTACAAGCATGGTGCTAGTTTAGTGGTGGGTCGCACAGTCGACTCTGGTACGGTACAGCTGGTCGCCTGTATCGAAGATCACCAGTTTCAACCCAAGAACTATTGGAACGGTCGGTGGCGTTCGGTGTGGTCTTTGACGGTCGGCGGGCCTGCTACAGAGTTACGTGGAACTCTACGTGTTCAAGTTCATTATTATGAGGATGGTAATGTACAACTTGTGAGCTCAAAGGAAATTAAGGCTCCTCTGGTGGCTAGCGGTGAAGTCGCCACTGCTAAAGAGTTCGTGCGGCTTGTCTCTGATGCAGAAAATACGTATCAAACTGCCATTTCAGACAATTACAAGACCATGAGCGACACAACGTTCAAAGCACTGAGACGACAACTACCTGTGACCCGCAGCAAGATTGACTGGGCTCGTCTTGTTTCTTACACGATCGGTAAGGAGCTCAAGAGCCAATGA

Protein

MAADGDEVISDQEKVRIVSDFILHSPPGEFNEVFNDVRVLLNNDTLLKEGASGAFAQYNKDQLTPVRLEGSELYTLITDHNELGGGRFFDPRSKCSFRYDHLRKEASEYEPYEPDRAAEPWRAALDEELTAYVAAHYKHGASLVVGRTVDSGTVQLVACIEDHQFQPKNYWNGRWRSVWSLTVGGPATELRGTLRVQVHYYEDGNVQLVSSKEIKAPLVASGEVATAKEFVRLVSDAENTYQTAISDNYKTMSDTTFKALRRQLPVTRSKIDWARLVSYTIGKELKSQ

Description

F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).

Subunit

Heterodimer of an alpha and a beta subunit.

Similarity

Belongs to the F-actin-capping protein alpha subunit family.

Keywords

Actin capping   Actin-binding   Complete proteome   Reference proteome  

Feature

chain  F-actin-capping protein subunit alpha

Uniprot

H9JT03   A0A194QWZ9   A0A194QF17   A0A1E1WDM6   A0A2H1WS37   A0A2W1BQV7   + More
A0A2A4J7F6   A0A0L7LJ82   A0A212FGF2   S4PAE9   D6WRI1   A0A088A627   A0A0L7R1Z8   A0A154P3S0   E2B5B7   A0A151HZP1   A0A158NC62   E9IM12   A0A195F9A8   A0A195CN90   A0A151XCQ4   A0A1B6HQG9   A0A1B6LHE9   A0A310SN37   A0A0J7NIW0   A0A1W4XP49   E2AYP3   A0A026WVL7   V5GVA1   A0A0C9Q5X5   J3JVU5   N6UF55   A0A1Y1K5N3   A0A232EJF2   A0A067QYV3   A0A0K8TNW5   K7IR84   A0A2J7PX86   A0A0L0C5M5   T1PHZ2   A0A1I8P8L5   U5EU77   Q16I64   A0A023EMK3   B4I7I4   B4QFL0   Q9W2N0   B3NK27   B4P9J2   A0A1W4V5X5   B3MDV9   A0A0P5PYC3   E9HL07   A0A0M3QUE6   A0A1L8E5K2   B4NN68   A0A1A9V626   F4WYV2   A0A1Q3EUF1   A0A1B0ARK0   A0A182PDR9   A0A1A9WHV4   A0A182VAZ1   A0A182KNZ2   Q7Q5Y1   A0A182RQX4   A0A1J1HI91   A0A084WER0   A0A0P4VN78   A0A182Y2R4   A0A182WJX1   A0A0P6I4S5   A0A182IMQ9   E0W2S1   W8BRT2   B4LNG9   A0A0T6B9C2   A0A0K8UH13   A0A182MM38   A0A034WVC3   A0A182QSV4   A0A0A1WRX5   A0A2I9LP04   A0A3R7QCH9   T1E2U7   B4H4Y4   Q28X29   T1JNV6   A0A3B0J161   T1DFJ8   A0A1D2NGM3   A0A182K4R5   A0A2M4AF83   A0A0L8GNQ0   A0A131XVK7   A0A2L2XWT3   A0A1S3JR53   A0A1S3D469   A0A182FEI7   A0A2M4CSF0  

Pubmed

19121390    26354079    28756777    26227816    22118469    23622113    + More
18362917    19820115    20798317    21347285    21282665    24508170    30249741    22516182    23537049    28004739    28648823    24845553    26369729    20075255    26108605    25315136    17510324    24945155    17994087    22936249    10731132    12537572    12537569    17550304    21292972    21719571    20966253    12364791    14747013    17210077    24438588    25244985    20566863    24495485    25348373    25830018    29248469    24330624    15632085    27289101    26561354   

EMBL

BABH01038957    KQ461073    KPJ09485.1    KQ459053    KPJ04138.1    GDQN01005971    + More
JAT85083.1    ODYU01010630    SOQ55871.1    KZ150068    PZC74113.1    NWSH01002895    PCG67352.1    JTDY01000905    KOB75490.1    AGBW02008682    OWR52807.1    GAIX01003294    JAA89266.1    KQ971351    EFA06446.1    KQ414667    KOC64843.1    KQ434809    KZC06589.1    GL445814    EFN89112.1    KQ976642    KYM78659.1    ADTU01011666    GL764129    EFZ18315.1    KQ981727    KYN37185.1    KQ977565    KYN01942.1    KQ982298    KYQ58161.1    GECU01030784    JAS76922.1    GEBQ01016844    JAT23133.1    KQ759828    OAD62665.1    LBMM01004406    KMQ92450.1    GL443983    EFN61406.1    KK107109    QOIP01000008    EZA59124.1    RLU19368.1    GALX01002864    JAB65602.1    GBYB01009518    JAG79285.1    BT127363    KB632025    AEE62325.1    ERL88094.1    APGK01029405    KB740734    ENN79256.1    GEZM01091886    JAV56723.1    NNAY01004010    OXU18500.1    KK852822    KDR15521.1    GDAI01001544    JAI16059.1    NEVH01020861    PNF20940.1    JRES01000960    KNC26729.1    KA647750    AFP62379.1    GANO01001608    JAB58263.1    CH478103    EAT33964.1    GAPW01003031    JAC10567.1    CH480824    EDW56559.1    CM000362    CM002911    EDX08002.1    KMY95425.1    AE013599    AY069084    CH954179    EDV55393.1    CM000158    EDW91312.1    CH902619    EDV36494.1    GDIQ01142444    LRGB01000141    JAL09282.1    KZS20632.1    GL732674    EFX67580.1    CP012524    ALC40499.1    GFDF01000185    JAV13899.1    CH964282    EDW85807.1    GL888463    EGI60606.1    GFDL01016217    JAV18828.1    JXJN01002473    AAAB01008960    EAA10831.2    CVRI01000001    CRK86190.1    ATLV01023245    KE525341    KFB48704.1    GDRN01147850    JAI56642.1    GDIQ01010478    JAN84259.1    DS235879    EEB19927.1    GAMC01002505    GAMC01002504    JAC04051.1    CH940648    EDW62149.1    LJIG01003010    KRT83930.1    GDHF01029648    GDHF01026689    GDHF01008611    JAI22666.1    JAI25625.1    JAI43703.1    AXCM01003909    GAKP01000670    GAKP01000669    JAC58282.1    AXCN02000522    GBXI01013099    GBXI01006354    JAD01193.1    JAD07938.1    GFWZ01000118    MBW20108.1    QCYY01003454    ROT63295.1    GALA01000970    JAA93882.1    CH479210    EDW32820.1    CM000071    EAL26487.1    JH432004    OUUW01000001    SPP74854.1    GAMD01003111    JAA98479.1    LJIJ01000045    ODN04389.1    GGFK01006130    MBW39451.1    KQ421056    KOF78522.1    GEFM01004463    JAP71333.1    IAAA01004788    LAA00496.1    GGFL01004069    MBW68247.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000218220    UP000037510    UP000007151    + More
UP000007266    UP000005203    UP000053825    UP000076502    UP000008237    UP000078540    UP000005205    UP000078541    UP000078542    UP000075809    UP000036403    UP000192223    UP000000311    UP000053097    UP000279307    UP000030742    UP000019118    UP000215335    UP000027135    UP000002358    UP000235965    UP000037069    UP000095301    UP000095300    UP000008820    UP000001292    UP000000304    UP000000803    UP000008711    UP000002282    UP000192221    UP000007801    UP000076858    UP000000305    UP000092553    UP000007798    UP000078200    UP000007755    UP000092460    UP000075885    UP000091820    UP000075903    UP000075882    UP000007062    UP000075900    UP000183832    UP000030765    UP000076408    UP000075920    UP000075880    UP000009046    UP000008792    UP000075883    UP000075886    UP000283509    UP000008744    UP000001819    UP000268350    UP000094527    UP000075881    UP000053454    UP000085678    UP000079169    UP000069272   

PRIDE

H9JT03    Q9W2N0   

Pfam

PF01267   F-actin_cap_A

Interpro

IPR037282   CapZ_alpha/beta        + More
IPR002189   CapZ_alpha       
IPR042276   CapZ_alpha/beta_2       
IPR017865   F-actin_cap_asu_CS       

SUPFAM

SSF90096   SSF90096       

Gene 3D

2.40.160.80    

ProteinModelPortal

H9JT03   A0A194QWZ9   A0A194QF17   A0A1E1WDM6   A0A2H1WS37   A0A2W1BQV7   + More
A0A2A4J7F6   A0A0L7LJ82   A0A212FGF2   S4PAE9   D6WRI1   A0A088A627   A0A0L7R1Z8   A0A154P3S0   E2B5B7   A0A151HZP1   A0A158NC62   E9IM12   A0A195F9A8   A0A195CN90   A0A151XCQ4   A0A1B6HQG9   A0A1B6LHE9   A0A310SN37   A0A0J7NIW0   A0A1W4XP49   E2AYP3   A0A026WVL7   V5GVA1   A0A0C9Q5X5   J3JVU5   N6UF55   A0A1Y1K5N3   A0A232EJF2   A0A067QYV3   A0A0K8TNW5   K7IR84   A0A2J7PX86   A0A0L0C5M5   T1PHZ2   A0A1I8P8L5   U5EU77   Q16I64   A0A023EMK3   B4I7I4   B4QFL0   Q9W2N0   B3NK27   B4P9J2   A0A1W4V5X5   B3MDV9   A0A0P5PYC3   E9HL07   A0A0M3QUE6   A0A1L8E5K2   B4NN68   A0A1A9V626   F4WYV2   A0A1Q3EUF1   A0A1B0ARK0   A0A182PDR9   A0A1A9WHV4   A0A182VAZ1   A0A182KNZ2   Q7Q5Y1   A0A182RQX4   A0A1J1HI91   A0A084WER0   A0A0P4VN78   A0A182Y2R4   A0A182WJX1   A0A0P6I4S5   A0A182IMQ9   E0W2S1   W8BRT2   B4LNG9   A0A0T6B9C2   A0A0K8UH13   A0A182MM38   A0A034WVC3   A0A182QSV4   A0A0A1WRX5   A0A2I9LP04   A0A3R7QCH9   T1E2U7   B4H4Y4   Q28X29   T1JNV6   A0A3B0J161   T1DFJ8   A0A1D2NGM3   A0A182K4R5   A0A2M4AF83   A0A0L8GNQ0   A0A131XVK7   A0A2L2XWT3   A0A1S3JR53   A0A1S3D469   A0A182FEI7   A0A2M4CSF0  

PDB

3LK4     E-value=4.02693e-97,     Score=904

KEGG

101738938    K10364 capping protein (actin filament) muscle Z-line, alpha | (RefSeq) F-actin-capping protein subu

PATHWAY

04144    Endocytosis - Bombyx mori (domestic silkworm)

GO

GO:0003779   GO:0008290   GO:0051016   GO:0051015   GO:0030479   GO:0030036   GO:0007015   GO:0016324   GO:0035220   GO:0005912   GO:0010591   GO:0046982   GO:0051490   GO:0046329   GO:0000902   GO:0007294   GO:0005869   GO:0007018   GO:0030837   GO:0051489   GO:0071203   GO:0032403   GO:0003676   GO:0016020   GO:0005515   GO:0006811   GO:0005622   GO:0006810   GO:0003824  

PANTHER

PTHR10653  

Length:

288

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00024

Exp number, first 60 AAs:

0

Total prob of N-in:

0.02250

outside

1  -  288

 

 

Pi

186.020888

Theta

197.419498

Tajima's D

-0.397055

CLR

19.786213

CSRT

0.261036948152592

Interpretation

Uncertain