Gene

KWMTBOMO11137

Pre Gene Modal

BGIBMGA014358

Annotation

endonuclease-reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr18(-):14449230-14452953      View in EpiBrowser

Full name

Guanylate cyclase      

Location in the cell

Nuclear   Reliability : 3.083

CDS

ATGGATGATAAGTTAACACCAATTATAGAAGAAAATTTGTTTCTAAAGAATGAAGTAGAGAAATTAAATGAGAAAGTAAAACGCCTAGAATTTGGTAAAAAGGAGAATAATTTAATACTCTACGGCTTCGAGGAATCGAATGAACATATTAACATAGTGGAAATGGTATCAAAAACTTTAAGCGATTCGGGTATCGAAGTGCATAAAACAGATATTAACAAAGCGTTTAGAATTGGTAAAGTAAAAGAAAAAGCACGCCCAATTTTAATTAATATGCTAAACGCATGGAAGAGAGATGAGATTTTGCGAAATAAGAAAAAGCTGCCAAAAAATATTTATGTTAAAGAGGATTTCAGTAAAGAAGTTTTAGAAAGAAGGAAAGAACTAATACCGCAGTTAAAGGAAGAACGAAAAAAGGGACGTATAGCATACATAAAATACGACAAACTAGTTATTGAAGGTTTAAGTGAAGTAAGAAGATTAGGTGAGAGCATTGAAGATAGAAAGGAATATGTCTTATACTATAAAGGGGAAACAAAGGGAAGTTACGGTGTCGGCTTCATGATTAAAAAACGCTTAGAAAAAAATATTGAAGAATTTATAGGTATATCAGAGAGAATAGCTGTACTAAATATGCATCTGCCGGGCTACAAATACAAATGGTCGATTATTCAAGTATATGCTCCCACTGAACAACAAGACGAACGGGTTAAAGACATCTTCTATGATCAGCTGTCATCAGTCTTACAGGATGCACACAAAAACATTATGGTTATAGGAGATTTTAATGGTAGAATAGGGTCTCAACGAACTGGTGAAGAAAATATAATAGGCAAATTTGGCTACGGTAGAAGAAGTAAAAATGGAGAAAGAATGATTAAAATGGCATTGGAAAACAATCTTGCATTCATGAACAGTTTTTTTAGAAAAGATCCGAAGAAAAAGTGGACCTGGTTATCTCCAGATGGATCATACAAGAACGAAATAGATTACATAGCAACGAACAAGAAAATGTTCTTTCATGATATAAACATTTTAAACCAATTTAACTTCAGTACCAACCACCGGATAGTGAGAGCAGAAATAAATATCACTGTACCCAAAAAGAGTAGAAACAAATACAATGCAAAAGCTAACTTTATAAATACACAACAACAATGTTTCATAAATACACCTAAAAACGAAATAGAATATAAATATAACAATGAGATAAAAGAAATATATGGTCCACTGTTCAACAAATCCGCAAAGCCCAAGACAACCTATACAGAAAATGACACTAAAACATTAATAGAAGAAAGAAGAAAACTTTTAAAACTTGGAAAAGACAAAGAAAATCTAAGGGCCATATCAAAATTAAGTAAAAAAATAAGTAACAGCATAAAAAATGATAGAACTAAGAAAAGAACGAATGTACTTAATTACCATATAAACAAGACAGAAGGAGTTAAAAAAGCTTTGAAAGAACTGATAGAGGCGAAAAAATGGATCCCAAACATTAAAAATAAAGCAGGAACACAGCAAACGACAAGAAAAGCTATAATACAGACAGCAACTAACTTCTATAGAAAACTTTATGCAACAGAACGAAACACAAGAGACTTAACTCTAAATCTCGATAGTGACGACATGGACGAAGACATACCAGTTTTCCTACAATCAGAGATAGAAAAAGCTGTCAACAGTCAAAAGAACAATAAAGCTCCTGGACCAGATCAAATTTCAAACGAAATGATCAAAATCTCAATTAGAGTACCAGAAAAGCTAAGAAAACTCACGGAAATATACAATTCTATTTTAAGCTCAGAATGTATACCATCGCAATGGACCAAGAGCACAATTATACTATTACACAAAAAAGGGGATAGGAATATTATAGAAAACTACAGGCCTATAAGCCTTATGTCGAATATTTATAAAGTGTTCTCCAAATTGTTATTGAACAGAATAACAGGAATAATGGACGAACAACAACCTATAGAACAAGCTGGTTTCAGAGCGGGGTTTTCAACTACTGATCACATGCATGTCATCAAACAGCTAATAGAAAAATGTCAAGAATACGGTAAAGCCTTGTACATCGCATTTGTGGACTATAGTAAAGCATTTGATTCTATAGAACACGATTTGCTTTGGAGAGCTCTAATCCAGCAGGGAGTGCCAATAAAATACATACGTATAGTTAAAAATATATATGCAAATAGCACAGCGCAAATAAAACTGGAATCAACCGGTGAAGAGTTCCCAATAGCTAGAGGTGTGAGGCAAGGAGATCCTCTATCGCCAAAACTTTTTTCGGCAGTCTTGGAAAGCATATTCAGAGATCTTGAGTGGGACAATTTTGGCATTAATATCAACGGTAGACAACTTAACCACTTAAGATTCGCTGATGACTTAGTCCTAATAACTGACAACGCGAAGACCCTTCAACAGATGCTACAACAGCTAGCTGAGGCAAGCAGAGTAGTTGGCCTTACTATAAATCGATCAAAAACAAAAGTAATGACAAACAGAGAAGAAATACTCATAAAAGTAGACAATGAAGATATTGAATATGTTAAAAACTATACATACTTAGGACAATTACTGTCTTTTAGAGACCGGACAGACATAGAAATCGAAAGCAGAGTGGCCTGTGCTTGGAAACGATACTGGTCCCTTAAAGAGATATTTAAAAGCAAACACTTTCCTATGACAGCCAAGAAAAAAGTGTTTAATTCTTGCATCTTGCCATGCCTCACGTATGGGTGCCAAACATGGGCATTGACTCAAAAAAATCTTTTAAAACTAAGATCGTGTCAAAGGAGTATGGAAAGGAGTATGTTAGGCGTGACGCTAAAAGACCGCAAAAGAGCAGCAGACATTAGATGTACAACAAAGGTGGAAGATGTACTAAAGAAGATAAGACAGTTAAAATGGCGATGGACTGGACATATGACAAGGGAAAGCAGAATGAAATGGACTAAAATTATAACAGAATGGCAGCCACGTGATGGCAAAAGAAAAAGAGGTAGGCAAGCTAGAAGATGGACAGATGATATAAAGATGATTGGAGGGACAATTTGGTCCAGAAAAGCTAGCAATAGAGAAGAATGGAAGCAGCTGGAAGAGGCCTATGTGTCACAGGACACGCTGATCACTGAACCGGGAAACCCGATGTATTAG

Protein

MDDKLTPIIEENLFLKNEVEKLNEKVKRLEFGKKENNLILYGFEESNEHINIVEMVSKTLSDSGIEVHKTDINKAFRIGKVKEKARPILINMLNAWKRDEILRNKKKLPKNIYVKEDFSKEVLERRKELIPQLKEERKKGRIAYIKYDKLVIEGLSEVRRLGESIEDRKEYVLYYKGETKGSYGVGFMIKKRLEKNIEEFIGISERIAVLNMHLPGYKYKWSIIQVYAPTEQQDERVKDIFYDQLSSVLQDAHKNIMVIGDFNGRIGSQRTGEENIIGKFGYGRRSKNGERMIKMALENNLAFMNSFFRKDPKKKWTWLSPDGSYKNEIDYIATNKKMFFHDINILNQFNFSTNHRIVRAEINITVPKKSRNKYNAKANFINTQQQCFINTPKNEIEYKYNNEIKEIYGPLFNKSAKPKTTYTENDTKTLIEERRKLLKLGKDKENLRAISKLSKKISNSIKNDRTKKRTNVLNYHINKTEGVKKALKELIEAKKWIPNIKNKAGTQQTTRKAIIQTATNFYRKLYATERNTRDLTLNLDSDDMDEDIPVFLQSEIEKAVNSQKNNKAPGPDQISNEMIKISIRVPEKLRKLTEIYNSILSSECIPSQWTKSTIILLHKKGDRNIIENYRPISLMSNIYKVFSKLLLNRITGIMDEQQPIEQAGFRAGFSTTDHMHVIKQLIEKCQEYGKALYIAFVDYSKAFDSIEHDLLWRALIQQGVPIKYIRIVKNIYANSTAQIKLESTGEEFPIARGVRQGDPLSPKLFSAVLESIFRDLEWDNFGININGRQLNHLRFADDLVLITDNAKTLQQMLQQLAEASRVVGLTINRSKTKVMTNREEILIKVDNEDIEYVKNYTYLGQLLSFRDRTDIEIESRVACAWKRYWSLKEIFKSKHFPMTAKKKVFNSCILPCLTYGCQTWALTQKNLLKLRSCQRSMERSMLGVTLKDRKRAADIRCTTKVEDVLKKIRQLKWRWTGHMTRESRMKWTKIITEWQPRDGKRKRGRQARRWTDDIKMIGGTIWSRKASNREEWKQLEEAYVSQDTLITEPGNPMY

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Uniprot

D7F179   D7F176   A0A2H1WF27   D7F178   A0A023EXV2   A0A2H1VS24   + More
D7F177   A0A069DZM5   A0A2W1BZV1   D7F157   D7F159   D7F165   D7F164   D7F166   D7F160   D7F158   A0A016S1D2   A0A016WCB8   A0A016ULU9   A0A016WPY4   A0A016T7J7   A0A016S795   A0A016WA79   A0A016VVN3   A0A016S5B2   A0A016VEC1   A0A016VCD9   E3NGJ2   E3NC15   A0A023EWU8   A0A016VCU3   A0A016VBP7   E3MH09   A0A016T590   A0A016SGC3   A0A016VCK8   A0A016SX67   A0A0P4VWD0   A0A016WEQ1   A0A016T4C4   A0A016S7F6   A0A016S403   A0A016V419   A0A016U784   A0A016W1X2   A0A016TX70   A0A016T636   A0A016WYN9   A0A016U6B7   A0A016WPX9   A0A016SCL7   A0A016UJS4   A0A016SY13   A0A016TK92   A0A016VLP0   A0A016WFS9   A0A016VGA0   A0A016WQM8   A0A016SCZ8   A0A016U123   A0A016WUN2   A0A016VT25   A0A016TQJ1   A0A016X207   A0A016SPR9   A0A2H2JFN0   A0A016SXL6   A0A016SCT9   A0A016S4W9   A0A016S6J0   A0A016V007   A0A016SG46   A0A016S4J2   A0A016TK11   A0A016W4R1   A0A016TNL1   A0A016WN14   A0A016WNH0   K7IG36   A0A016SQY7   A0A016S3N7   A0A016V6A2   A0A016TNH6   A0A016US53   A0A016WS23   A0A016T5Z1   A0A016TNS4   A0A2W5U8K4   A0A016URH5   K7IG35   A0A016TMT8  

EC Number

4.6.1.2

Pubmed

20470440    25474469    26334808    28756777    25730766    27129103    + More

EMBL

FJ265564    ADI61832.1    FJ265561    ADI61829.1    ODYU01008249    SOQ51673.1    + More
FJ265563    ADI61831.1    GBBI01004876    JAC13836.1    ODYU01004088    SOQ43598.1    FJ265562    ADI61830.1    GBGD01000380    JAC88509.1    KZ149907    PZC78256.1    FJ265542    ADI61810.1    FJ265544    ADI61812.1    FJ265550    ADI61818.1    FJ265549    ADI61817.1    FJ265551    ADI61819.1    FJ265545    ADI61813.1    FJ265543    ADI61811.1    JARK01001655    EYB84321.1    JARK01000388    EYC37469.1    JARK01001370    EYC16150.1    JARK01000173    EYC41342.1    JARK01001736    JARK01001462    JARK01001379    JARK01001338    EYB80775.1    EYB98943.1    EYC13646.1    EYC33347.1    JARK01001621    EYB86109.1    JARK01000460    EYC36749.1    JARK01001340    EYC30828.1    JARK01001626    EYB85833.1    JARK01001348    EYC25048.1    EYC25050.1    DS268655    EFO97114.1    DS268591    EFO92565.1    GBBI01004877    JAC13835.1    EYC25046.1    EYC25049.1    DS268444    EFP01729.1    JARK01001473    EYB97806.1    JARK01001568    EYB89432.1    EYC25145.1    JARK01001500    JARK01001343    EYB95040.1    EYC28825.1    GDKW01001596    JAI54999.1    JARK01000347    EYC38051.1    JARK01001475    EYB97550.1    JARK01001612    EYB86585.1    JARK01001639    EYB85201.1    JARK01001354    EYC21986.1    JARK01001389    EYC11015.1    EYC33297.1    JARK01001407    EYC07212.1    JARK01001470    JARK01000204    EYB98081.1    EYC40601.1    JARK01000063    EYC44387.1    EYC10874.1    JARK01000161    EYC41641.1    JARK01001628    JARK01001583    JARK01001528    JARK01001506    JARK01001467    JARK01001463    JARK01001457    JARK01001432    JARK01001420    JARK01001403    JARK01001371    JARK01001369    JARK01001360    JARK01001353    JARK01001349    JARK01000603    JARK01000080    EYB85741.1    EYB88438.1    EYB92544.1    EYB94540.1    EYB98080.1    EYB98468.1    EYB98899.1    EYB99568.1    EYC03088.1    EYC05014.1    EYC08153.1    EYC15852.1    EYC16408.1    EYC19456.1    EYC22445.1    EYC24734.1    EYC24778.1    EYC24866.1    EYC33488.1    EYC35672.1    EYC43798.1    JARK01001372    EYC15614.1    JARK01001497    EYB95322.1    EYC03125.1    JARK01001344    EYC28216.1    JARK01000302    EYC38674.1    JARK01001346    EYC26445.1    JARK01000165    EYC41537.1    JARK01001581    EYB88505.1    JARK01001401    EYC08686.1    JARK01000109    EYC42952.1    EYC30744.1    JARK01001421    EYC04912.1    JARK01000008    EYC46079.1    JARK01001531    EYB92324.1    EYB95049.1    JARK01001582    EYB88498.1    JARK01001637    EYB85284.1    JARK01001618    EYB86258.1    JARK01001357    EYC20551.1    JARK01001565    EYB89683.1    EYB85282.1    JARK01001676    JARK01001446    JARK01001433    EYB83199.1    EYC01126.1    EYC02928.1    JARK01001337    EYC34625.1    JARK01001424    EYC04316.1    JARK01000177    EYC41209.1    EYC41210.1    JARK01001524    EYB92970.1    EYB85285.1    EYC22263.1    EYC04315.1    JARK01001365    EYC18010.1    JARK01000146    EYC42042.1    EYB98082.1    EYC40602.1    EYC04317.1    QFQQ01000179    PZR20596.1    EYC18009.1    EYC04314.1   

Proteomes

UP000024635    UP000008281    UP000005237   

PRIDE

D7F179    D7F176    D7F178    D7F177    D7F157    D7F159    + More
D7F165    D7F164    D7F166    D7F160    D7F158   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF00211   Guanylate_cyc
PF07714   Pkinase_Tyr
PF01094   ANF_receptor
PF03372   Exo_endo_phos

Interpro

IPR005135   Endo/exonuclease/phosphatase        + More
IPR036691   Endo/exonu/phosph_ase_sf       
IPR000477   RT_dom       
IPR029052   Metallo-depent_PP-like       
IPR001828   ANF_lig-bd_rcpt       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR001170   ANPR/GUC       
IPR011009   Kinase-like_dom_sf       
IPR028082   Peripla_BP_I       
IPR001054   A/G_cyclase       
IPR000719   Prot_kinase_dom       
IPR029787   Nucleotide_cyclase       

SUPFAM

SSF56219   SSF56219        + More
SSF56112   SSF56112       
SSF53822   SSF53822       
SSF55073   SSF55073       

Gene 3D

3.60.10.10     3.60.21.10     3.30.70.1230    

ProteinModelPortal

D7F179   D7F176   A0A2H1WF27   D7F178   A0A023EXV2   A0A2H1VS24   + More
D7F177   A0A069DZM5   A0A2W1BZV1   D7F157   D7F159   D7F165   D7F164   D7F166   D7F160   D7F158   A0A016S1D2   A0A016WCB8   A0A016ULU9   A0A016WPY4   A0A016T7J7   A0A016S795   A0A016WA79   A0A016VVN3   A0A016S5B2   A0A016VEC1   A0A016VCD9   E3NGJ2   E3NC15   A0A023EWU8   A0A016VCU3   A0A016VBP7   E3MH09   A0A016T590   A0A016SGC3   A0A016VCK8   A0A016SX67   A0A0P4VWD0   A0A016WEQ1   A0A016T4C4   A0A016S7F6   A0A016S403   A0A016V419   A0A016U784   A0A016W1X2   A0A016TX70   A0A016T636   A0A016WYN9   A0A016U6B7   A0A016WPX9   A0A016SCL7   A0A016UJS4   A0A016SY13   A0A016TK92   A0A016VLP0   A0A016WFS9   A0A016VGA0   A0A016WQM8   A0A016SCZ8   A0A016U123   A0A016WUN2   A0A016VT25   A0A016TQJ1   A0A016X207   A0A016SPR9   A0A2H2JFN0   A0A016SXL6   A0A016SCT9   A0A016S4W9   A0A016S6J0   A0A016V007   A0A016SG46   A0A016S4J2   A0A016TK11   A0A016W4R1   A0A016TNL1   A0A016WN14   A0A016WNH0   K7IG36   A0A016SQY7   A0A016S3N7   A0A016V6A2   A0A016TNH6   A0A016US53   A0A016WS23   A0A016T5Z1   A0A016TNS4   A0A2W5U8K4   A0A016URH5   K7IG35   A0A016TMT8  

PDB

6AR3     E-value=1.64285e-07,     Score=137

KEGG

101738214    no KO assigned | (RefSeq) uncharacterized LOC101738214

GO

GO:0003964   GO:0004519   GO:0005524   GO:0016021   GO:0035556   GO:0004672   GO:0004383  

Length:

1054

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00468

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00001

outside

1  -  1054

 

 

Pi

3.178207

Theta

24.097095

Tajima's D

-0.918791

CLR

396.275778

CSRT

0.153742312884356

Interpretation

Possibly Positive selection