Gene

KWMTBOMO11127  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008214

Annotation

PREDICTED:_fumarate_hydratase?_mitochondrial-like_[Papilio_polytes]

Location

Bomo_Chr18(-):13684827-13711320      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.201 Mitochondrial   Reliability : 1.684

CDS

ATGGCTTGCACGACATGTCTCAACCCAGAAGGCAAGCCGGTCAAAACGAGGAAGGAAAAAGATACCTTTGGGGAGCTGGACGTGCCAGATGACAAGCTATATGGCGCGCAGACCGTGCGTTCGGTGATGAACTTCCCGATCGGTGGAATTGAGGAACGCATGCCTTATCCCGTGATTGTCGCTTTCGGTATACTAAAGAAAGCAGCCGCCAAAGTCAATATCGAATATGGACTTGAAAAGAAAATTGCCGACGCGATCATGCAGGCCTGCGATGACGTCATCAGCGGGAAGCTCTACCGCGAGGGTCACTTCCCCCTCGTCATCTGGCAGACTGGCTCCGGTACTCAGTCCAACATGAACACGAACGAGGTGATTGCGAACCGCGCCATACAAATACTGGGCGGGAAACTGGGCAGCAAGGACCCGGTGCATCCCAACGACCACGTGAACAAGTCGCAGAGCTCGAACGACACGTACCCCACCGCCATGCACATCGCCGTGGCCATGGAGCTCCGGGACAGGCTCATGCCGGGCCTCGTGGCCCTCAGGGACACGCTGCAGGCCAAGAGCAAGGACTTTGAGAGGATCGTCAAAATTGGAAGGACCCACCTGATGGACGCGGTGCCGCTGACGCTGGGCCAGGAGTTCAGCGGGTACGCGGCGCAGCTGTCGTACGGCGTGGAGCGCGTGTGCGCCACGCTGCCGCGCCTGCACTACCTGGCGCTGGGCGGCACGGCCGTCGGCACCGGCCTCAACACCAGGATCGGCTTCGCGGAGAAGTGCGCCGCCGAGATCGCCGCGCTCACCGGTATACCGTTCGAGACGGCGCCGAACAAGTTCGAGGCGCTGGCGTGCCACGACGCCATGGTGGAGGTCTCCGGCGCGCTCAACACCATCGCCGTGTCGCTCATGAAGATCGCGAACGACATCCGACTGCTGGCCTCCGGGCCGCGCTGTGGACTCGCCGAGCTGATGTTGCCCGAGAACGAACCCGGATCCTCGATAATGCCCGGTAAAGTGAACCCGACGCAGTGCGAGGCGCTGACGATGGTGGCGGCGCAGGTGATGGGCAACCACGTGGCGTGCACGGTGGGCGGCAGCAACGGACACTTCGAGCTCAACGTGTTCAAGCCCATGATCGTGTCCAACGTGCTGCGGTCCATACGACTCATCGGCGACGGCTGCCAGGCCTTCAACAAGAACTGCGCCGTGGGCATCAAGGCTAACGAAGTGCAGATCGCGAAGATCATGCGCGAGTCTCTAATGCTGGTGACGGCGCTCAACCCACACATCGGCTACGACAAGGCGGCTCAAATCGCGAAGACCGCGCACAAGGAAGGCGGAAACCTGAAGGATACCGCGATCAAGCTGGGCATCCTCACCGCCGAGCAGTTCGACCAGTGGGTCAAACCCGAAGACATGCTCGGACCCAAGTAG

Protein

MACTTCLNPEGKPVKTRKEKDTFGELDVPDDKLYGAQTVRSVMNFPIGGIEERMPYPVIVAFGILKKAAAKVNIEYGLEKKIADAIMQACDDVISGKLYREGHFPLVIWQTGSGTQSNMNTNEVIANRAIQILGGKLGSKDPVHPNDHVNKSQSSNDTYPTAMHIAVAMELRDRLMPGLVALRDTLQAKSKDFERIVKIGRTHLMDAVPLTLGQEFSGYAAQLSYGVERVCATLPRLHYLALGGTAVGTGLNTRIGFAEKCAAEIAALTGIPFETAPNKFEALACHDAMVEVSGALNTIAVSLMKIANDIRLLASGPRCGLAELMLPENEPGSSIMPGKVNPTQCEALTMVAAQVMGNHVACTVGGSNGHFELNVFKPMIVSNVLRSIRLIGDGCQAFNKNCAVGIKANEVQIAKIMRESLMLVTALNPHIGYDKAAQIAKTAHKEGGNLKDTAIKLGILTAEQFDQWVKPEDMLGPK

Uniprot

A0A194QGT0   A0A3S2NWW1   A0A212FD89   A0A2A4J6U7   A0A2A4J8E6   A0A2P2HWJ0   + More
A0A0P6HAL0   A0A164UQE4   A0A0P5AQE4   A0A0P5WFX5   A0A0P4Z162   A0A0P4Z575   A0A1B6DEC2   A0A0P4ZX14   A0A0P4W0E3   A0A0P4WKR2   A0A0N8DEZ3   A0A0P5AHC3   A0A067RC82   A0A0P4Y303   A0A0P5UV22   D6WJB5   A0A0P5AV08   A0A2J7QFV6   A0A0K8TP15   A0A226DFQ0   A0A1B6LY95   A0A1B6M4A2   A0A0P4YHH7   A0A1B6M4Z2   J3JWN1   E9G631   A0A1Y1NNF0   A0A0A9ZG43   A0A0K8SZE8   A0A1B0BFU9   A0A0A9VTT8   A0A0V0G2W0   A0A131XLG2   A0A336M2X4   A0A023F8L2   A0A1A9WX41   A0A183V4U9   A0A0B2W747   A0A0P4VRQ8   R4G3D9   A0A224XB57   A0A0L0CCU3   T1PF85   A0A023FML9   A0A1I8MGA2   A0A224YTD0   A0A1E1X8T3   A0A1L8E0K1   D3TRM2   A0A1Q3FXD1   L7MAJ1   A0A0N5D7Z7   A0A0K8RRH9   A0A023FXJ5   A0A1B0C9J4   A0A044UT14   A0A131Y282   A0A131YZZ7   A0A0K0ERT9   A0A2R5L3V8   A0A1B0FPJ0   A0A034WU78   A0A3R7MKT2   A0A1I8Q8J9   A0A0N4UE62   A0A023GL08   A0A1L8EIC7   A0A1I7V645   A0A090L4W0   W8C4W4   A0A0K8W113   A0A1B0CZT8   A0A093HHV5   A0A0K0F078   A0A034WQ88   A0A3P6SMA9   A0A2L2Y0V8   A0A0K8V062   A0A0N4ZY61   U5ER71   A0A1I8Q8G5   A0A0N4SYP7   A0A0N4V9E7   A0A182H3I1   A0A2P4T4E1   W8CB07   A0A2H8TNT8   A0A0M3IDA0   F1KYQ0   A0A023ESX8   A0A087U8E2   A0A0A1WRX6   A0A2U3WXM3   A0A0N5CCQ0  

Pubmed

26354079    22118469    24845553    18362917    19820115    26369729    + More
22516182    21292972    28004739    25401762    26823975    28049606    25474469    27129103    26108605    25315136    28797301    28503490    20353571    25576852    26830274    25348373    25217238    24495485    26561354    26483478    21685128    24945155    25830018   

EMBL

KQ458880    KPJ04624.1    RSAL01000124    RVE46603.1    AGBW02009093    OWR51702.1    + More
NWSH01002687    PCG67681.1    PCG67682.1    IACF01000199    LAB66000.1    GDIQ01023218    JAN71519.1    LRGB01001579    KZS11579.1    GDIP01199287    GDIP01140511    GDIP01052313    GDIP01052312    JAJ24115.1    GDIP01087151    GDIP01087150    JAM16565.1    GDIP01219180    JAJ04222.1    GDIP01219179    JAJ04223.1    GEDC01013302    JAS23996.1    GDIP01207536    JAJ15866.1    GDRN01082458    JAI61831.1    GDRN01082461    JAI61828.1    GDIP01040303    JAM63412.1    GDIP01201939    GDIP01201938    GDIP01201937    JAJ21463.1    KK852559    KDR21372.1    GDIP01234535    JAI88866.1    GDIP01109137    JAL94577.1    KQ971343    EFA03144.1    GDIP01193736    JAJ29666.1    NEVH01014841    PNF27471.1    GDAI01001695    JAI15908.1    LNIX01000022    OXA43401.1    GEBQ01011309    GEBQ01002560    JAT28668.1    JAT37417.1    GEBQ01009244    JAT30733.1    GDIP01227336    JAI96065.1    GEBQ01008987    JAT30990.1    BT127649    AEE62611.1    GL732533    EFX85065.1    GEZM01000257    JAV98445.1    GBHO01002684    GDHC01010977    JAG40920.1    JAQ07652.1    GBRD01007516    JAG58305.1    JXJN01013667    JXJN01013668    GBHO01044973    GBRD01009684    JAF98630.1    JAG56140.1    GECL01003640    JAP02484.1    GEFH01000662    JAP67919.1    UFQS01000116    UFQT01000116    SSW99958.1    SSX20338.1    GBBI01001025    JAC17687.1    UYWY01023084    VDM47090.1    JPKZ01000060    KHN89095.1    GDKW01002018    JAI54577.1    ACPB03015646    GAHY01001766    JAA75744.1    GFTR01006780    JAW09646.1    JRES01000586    KNC30032.1    KA647406    AFP62035.1    GBBK01002352    JAC22130.1    GFPF01007853    MAA18999.1    GFAC01003505    JAT95683.1    GFDF01001853    JAV12231.1    EZ424074    ADD20350.1    GFDL01002785    JAV32260.1    GACK01004905    JAA60129.1    UYYF01004751    VDN06822.1    GADI01000574    JAA73234.1    GBBL01001068    JAC26252.1    AJWK01002422    CMVM020000228    GEFM01003326    JAP72470.1    GEDV01004487    JAP84070.1    GGLE01000029    MBY04155.1    CCAG010016286    GAKP01001227    JAC57725.1    QCYY01000280    ROT85431.1    UYYG01000006    VDN50720.1    GBBM01000909    JAC34509.1    GFDG01000423    JAV18376.1    JH712156    EFO24875.2    LN609528    CEF64732.1    GAMC01005254    JAC01302.1    GDHF01007543    JAI44771.1    AJVK01009722    KL206415    KFV82233.1    GAKP01001226    JAC57726.1    UYRX01000012    VDK68625.1    IAAA01001375    LAA01801.1    GDHF01020334    JAI31980.1    GANO01002936    JAB56935.1    UZAD01000049    VDN82053.1    UXUI01008568    VDD91828.1    JXUM01003817    JXUM01003818    JXUM01003819    JXUM01003820    KQ560164    KXJ84062.1    PPHD01009224    POI31235.1    GAMC01005256    JAC01300.1    GFXV01004021    MBW15826.1    JI168159    ADY43004.1    GAPW01001195    JAC12403.1    KK118699    KFM73631.1    GBXI01012916    JAD01376.1   

Proteomes

UP000053268    UP000283053    UP000007151    UP000218220    UP000076858    UP000027135    + More
UP000007266    UP000235965    UP000198287    UP000000305    UP000092460    UP000091820    UP000050794    UP000267007    UP000031036    UP000015103    UP000037069    UP000095301    UP000046394    UP000276776    UP000092461    UP000024404    UP000035681    UP000092444    UP000283509    UP000095300    UP000038040    UP000274756    UP000095285    UP000035682    UP000092462    UP000053584    UP000035680    UP000277928    UP000038045    UP000038020    UP000278627    UP000038041    UP000274131    UP000069940    UP000249989    UP000036681    UP000054359    UP000245340    UP000046392   

Pfam

PF00206   Lyase_1        + More
PF10415   FumaraseC_C

Interpro

IPR020557   Fumarate_lyase_CS        + More
IPR022761   Fumarate_lyase_N       
IPR018951   Fumarase_C_C       
IPR005677   Fum_hydII       
IPR000362   Fumarate_lyase_fam       
IPR024083   Fumarase/histidase_N       
IPR008948   L-Aspartase-like       

SUPFAM

SSF48557   SSF48557       

Gene 3D

1.10.275.10    

CDD

cd01362  Fumarase_classII

ProteinModelPortal

A0A194QGT0   A0A3S2NWW1   A0A212FD89   A0A2A4J6U7   A0A2A4J8E6   A0A2P2HWJ0   + More
A0A0P6HAL0   A0A164UQE4   A0A0P5AQE4   A0A0P5WFX5   A0A0P4Z162   A0A0P4Z575   A0A1B6DEC2   A0A0P4ZX14   A0A0P4W0E3   A0A0P4WKR2   A0A0N8DEZ3   A0A0P5AHC3   A0A067RC82   A0A0P4Y303   A0A0P5UV22   D6WJB5   A0A0P5AV08   A0A2J7QFV6   A0A0K8TP15   A0A226DFQ0   A0A1B6LY95   A0A1B6M4A2   A0A0P4YHH7   A0A1B6M4Z2   J3JWN1   E9G631   A0A1Y1NNF0   A0A0A9ZG43   A0A0K8SZE8   A0A1B0BFU9   A0A0A9VTT8   A0A0V0G2W0   A0A131XLG2   A0A336M2X4   A0A023F8L2   A0A1A9WX41   A0A183V4U9   A0A0B2W747   A0A0P4VRQ8   R4G3D9   A0A224XB57   A0A0L0CCU3   T1PF85   A0A023FML9   A0A1I8MGA2   A0A224YTD0   A0A1E1X8T3   A0A1L8E0K1   D3TRM2   A0A1Q3FXD1   L7MAJ1   A0A0N5D7Z7   A0A0K8RRH9   A0A023FXJ5   A0A1B0C9J4   A0A044UT14   A0A131Y282   A0A131YZZ7   A0A0K0ERT9   A0A2R5L3V8   A0A1B0FPJ0   A0A034WU78   A0A3R7MKT2   A0A1I8Q8J9   A0A0N4UE62   A0A023GL08   A0A1L8EIC7   A0A1I7V645   A0A090L4W0   W8C4W4   A0A0K8W113   A0A1B0CZT8   A0A093HHV5   A0A0K0F078   A0A034WQ88   A0A3P6SMA9   A0A2L2Y0V8   A0A0K8V062   A0A0N4ZY61   U5ER71   A0A1I8Q8G5   A0A0N4SYP7   A0A0N4V9E7   A0A182H3I1   A0A2P4T4E1   W8CB07   A0A2H8TNT8   A0A0M3IDA0   F1KYQ0   A0A023ESX8   A0A087U8E2   A0A0A1WRX6   A0A2U3WXM3   A0A0N5CCQ0  

PDB

3E04     E-value=0,     Score=1719

KEGG

101744897    K01679 fumarate hydratase, class II [EC:4.2.1.2] | (RefSeq) fumarate hydratase, mitochondrial-like

PATHWAY

00020    Citrate cycle (TCA cycle) - Bombyx mori (domestic silkworm)
00620    Pyruvate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)

GO

GO:0006106   GO:0045239   GO:0006099   GO:0004333   GO:0006108   GO:0005739   GO:0016829   GO:0003824   GO:0006811   GO:0005622   GO:0006810  

PANTHER

PTHR11444  

Length:

478

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.03274

Exp number, first 60 AAs:

0.0046

Total prob of N-in:

0.00514

outside

1  -  478

 

 

Pi

171.897976

Theta

163.875182

Tajima's D

-0.931553

CLR

1095.711034

CSRT

0.153192340382981

Interpretation

Uncertain