Gene

KWMTBOMO11111  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008228

Annotation

PREDICTED:_mitochondrial_import_inner_membrane_translocase_subunit_TIM44_[Papilio_xuthus]

Location

Bomo_Chr18(+):13179616-13185357      View in EpiBrowser

Full name

Mitochondrial import inner membrane translocase subunit TIM44      

Location in the cell

Cytoplasmic   Reliability : 1.135 Mitochondrial   Reliability : 1.832 Nuclear   Reliability : 1.417

CDS

ATGCATGCATATAGACAGTTATTATATAGTCCCGCTCGTTGGAAATGTGTTCTACCTTCGAGTTTGAAGACAACATCACTCTCGGCAAAATCAGACCAGTACACCATACAAGAATGTCGGCAGTATTCTGCAAGGAAAGGATTCTTCTCATCAATAATAGAGAACATCAAAGAGGATATTGCAAAGAACAAGGAAATGAAAGAGAATATAAAGAAGTTCAGAGAGGAGGCACAGAAACTTGAGAACTCGGAAGCTTTGCAAGCAGCTAGGAAAAAGTTTCACGCCGTTGAATCAGAAGCGTCGAAGAGTTCAGAAGTCTTGAAAGAAACTATTGAGGGTATCAAAGGAAAAATGGAGCATGTGCTAGAGGAGGCGAGTAAAAGTGATATAGCCAAAAAAGCAGGGAAAATTACGGAGGACATCTCGAAGACGGCTCGCAGTGCTGCGGAGGGTATAGCGGATAAAGGACAGAGAATTGGACAAACTTCTGCTTTCAGAACTATATCGCAGGCAACAGAAGTTGTGAAAAACGAAATGTCACCCCGAGGGCTCGAGGGGCGTGTCTACATCGCTCCTGTCGCCTTAAGGAAACGTATTGAGGTCGCAGAAGACGAAAGAACGTTTTCTCCGGACACCGAGACGACTGGAGTGGAATTGCACAAGGACTCAAAGTTTTATCAGCAGTGGGAGAACTTCAAGAACAACAATCAGTATGTTAATAAGGTTTTAGATTGGAAAATCAAATACGAAGAATCGGACAATCCAGTGGTGAGGGCGTCGCGGCTGCTCACAGAAAAGATGGGAAGTCTGTTCGGGAACATGTTTGAAAAGACTGAACTATCGAAAACGTTGACGGAAATCTGTAAAATCGACCCGAACTTCACCGCACAGAAATTTCTCGAAGACTGCGCCAACGATATCATACCGAACATTCTAGAGGCTATGGTCAGAGGAGACTTGGAAATACTGAAGGACTGGTGTTACGAGGGCGTGTTCAACATTCTCGCAACCCCGATCAAGCAGTGCAAGCAGCTGGGGTATCGGCTGGACTCCAAGATCCTCGACATCGAACAGATCGAGCTGGTGATGGGCAAGATGATGGACCAGGGGCCGGTCCTCGTCATCACGTTCCAATCGCAGCAGATAATGTGTGTCAGAGACGGCAAAGGGAATGTTATCGAAGGTTCTCCGGATAAAGTTATGAGGGTTAACTACGTGTGGGTGCTGTGCCGGGACCCCCAGGAGCTCAACCCCAAGTCGGCGTGGCGGCTGCTCGAGCTGTCAGCCAACAGTGTAGAACAACTGATATAG

Protein

MHAYRQLLYSPARWKCVLPSSLKTTSLSAKSDQYTIQECRQYSARKGFFSSIIENIKEDIAKNKEMKENIKKFREEAQKLENSEALQAARKKFHAVESEASKSSEVLKETIEGIKGKMEHVLEEASKSDIAKKAGKITEDISKTARSAAEGIADKGQRIGQTSAFRTISQATEVVKNEMSPRGLEGRVYIAPVALRKRIEVAEDERTFSPDTETTGVELHKDSKFYQQWENFKNNNQYVNKVLDWKIKYEESDNPVVRASRLLTEKMGSLFGNMFEKTELSKTLTEICKIDPNFTAQKFLEDCANDIIPNILEAMVRGDLEILKDWCYEGVFNILATPIKQCKQLGYRLDSKILDIEQIELVMGKMMDQGPVLVITFQSQQIMCVRDGKGNVIEGSPDKVMRVNYVWVLCRDPQELNPKSAWRLLELSANSVEQLI

Description

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.

Similarity

Belongs to the Tim44 family.

Uniprot

H9JFD1   A0A2A4K8T8   A0A194QGT8   A0A194RIL8   A0A3S2P6Z3   A0A2H1VKH2   + More
A0A212EGQ1   A0A0L7LS41   A0A336LG68   A0A336LJM1   A0A023ES42   Q16YW1   Q16KX3   A0A182N1F8   A0A1B0CX04   A0A182YEY2   A0A182IQ97   A0A1L8DVE6   A0A182XBX3   A0A182QP74   A0A182MG14   A0A0K8V197   A0A1Q3F8U0   A0A182IAL1   A0A182VCZ9   A0A0A1WJA7   A0A034WTB6   A0A1J1ICR4   A0A1B6D3A0   Q7QF41   W8C6R9   A0A182RM84   A0A182TZG1   U5EHB1   W5JGB4   B0XGL1   K7J9V8   A0A182FNE5   A0A2M4AQW7   A0A182K2Y8   A0A0L0CLS3   A0A2M3Z9Y3   A0A2J7PNM9   A0A182VV88   A0A2P8YIH1   A0A084VJ49   A0A2M4BPI0   R4FJG7   A0A067QYX4   A0A182PV85   T1PIV4   A0A1I8P7L8   A0A1B6MUF4   A0A154PRU2   A0A088A218   A0A1B6I6N2   A0A1B6ID16   A0A1B6EPK7   A0A2A3EN09   A0A0A9Y9X4   A0A1A9Z8D4   A0A3B0KM66   A0A0L7QUG5   A0A151I734   A0A0M4F6I9   A0A232EJH0   A0A0M8ZZ16   A0A2R7VX32   D3TNU6   A0A0P8YHU2   A0A0Q9WZS4   B4IHY3   A0A1A9UYY1   A0A158NPU8   B3M1N4   A0A0R1E578   B4K5K9   B4LWF9   A0A1W4UPI4   A0A151X8M2   A0A0R1E0Y3   A0A1W4UBA7   A0A195ATU3   Q50LB5   B4JII9   Q9VDZ8   C9QP57   A0A0Q9WDY9   B4PMS2   A0A1A9WY78   A0A0K8TLC2   A0A1W4UMV1   A0A1W4UMN0   A0A195DTR5   A0A151JST3   Q8IHE3   Q9VDZ7   Q50LB6   A0A0R3NM32   E2BW71  

Pubmed

19121390    26354079    22118469    26227816    24945155    26483478    + More
17510324    25244985    25830018    25348373    12364791    14747013    17210077    24495485    20920257    23761445    20075255    26108605    29403074    24438588    24845553    25315136    25401762    26823975    28648823    20353571    17994087    21347285    17550304    16143626    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    26369729    15632085    20798317   

EMBL

BABH01038264    BABH01038265    NWSH01000032    PCG80489.1    KQ458880    KPJ04634.1    + More
KQ460154    KPJ17284.1    RSAL01000264    RVE43290.1    ODYU01002804    SOQ40754.1    AGBW02015051    OWR40656.1    JTDY01000262    KOB78021.1    UFQS01003369    UFQT01003369    SSX15565.1    SSX34929.1    UFQS01005995    UFQT01004579    UFQT01005995    SSX16903.1    SSX35722.1    JXUM01012907    JXUM01093602    GAPW01001543    GAPW01001542    KQ564068    KQ560364    JAC12055.1    KXJ72843.1    KXJ82804.1    CH477507    EAT39827.1    CH477933    EAT34960.1    AJWK01033084    GFDF01003670    JAV10414.1    AXCN02001377    AXCM01003602    GDHF01019964    JAI32350.1    GFDL01011112    JAV23933.1    APCN01001262    GBXI01015814    JAC98477.1    GAKP01000181    JAC58771.1    CVRI01000044    CRK96766.1    GEDC01017243    JAS20055.1    AAAB01008846    EAA06726.4    GAMC01000967    JAC05589.1    GANO01003100    JAB56771.1    ADMH02001484    ETN62378.1    DS233038    EDS27675.1    AAZX01002793    GGFK01009791    MBW43112.1    JRES01000228    KNC33187.1    GGFM01004534    MBW25285.1    NEVH01023380    PNF17947.1    PYGN01000570    PSN44050.1    ATLV01013431    KE524855    KFB37993.1    GGFJ01005557    MBW54698.1    ACPB03008137    GAHY01002283    JAA75227.1    KK852867    KDR14720.1    KA647853    AFP62482.1    GEBQ01000401    JAT39576.1    KQ435078    KZC14457.1    GECU01025110    JAS82596.1    GECU01022889    JAS84817.1    GECZ01029903    JAS39866.1    KZ288215    PBC32586.1    GBHO01045164    GBHO01015188    GBRD01013649    GDHC01011471    GDHC01003494    JAF98439.1    JAG28416.1    JAG52177.1    JAQ07158.1    JAQ15135.1    OUUW01000013    SPP87669.1    KQ414735    KOC62302.1    KQ978456    KYM93898.1    CP012526    ALC47675.1    NNAY01004007    OXU18506.1    KQ435821    KOX72479.1    KK854110    PTY11461.1    CCAG010012055    EZ423098    ADD19374.1    CH902617    KPU80814.1    CH933806    KRG00825.1    CH480840    EDW49500.1    ADTU01022755    EDV44364.1    CM000160    KRK02826.1    EDW14046.1    CH940650    EDW66596.1    KQ982409    KYQ56726.1    KRK02825.1    KQ976745    KYM75477.1    AB194415    BAD98173.1    CH916369    EDV93070.1    AE014297    BT133180    AAF55640.1    AFA28421.1    BT099939    ACX36515.1    KRF82824.1    EDW95992.1    GDAI01002625    JAI14978.1    KQ980487    KYN15919.1    KQ982014    KYN30632.1    BT001289    BT011399    AAN71045.1    AAR96191.1    AAF55639.1    BAD98172.1    CM000070    KRS99925.1    GL451091    EFN80103.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000283053    UP000007151    + More
UP000037510    UP000069940    UP000249989    UP000008820    UP000075884    UP000092461    UP000076408    UP000075880    UP000076407    UP000075886    UP000075883    UP000075840    UP000075903    UP000183832    UP000007062    UP000075900    UP000075902    UP000000673    UP000002320    UP000002358    UP000069272    UP000075881    UP000037069    UP000235965    UP000075920    UP000245037    UP000030765    UP000015103    UP000027135    UP000075885    UP000095301    UP000095300    UP000076502    UP000005203    UP000242457    UP000092445    UP000268350    UP000053825    UP000078542    UP000092553    UP000215335    UP000053105    UP000092444    UP000007801    UP000009192    UP000001292    UP000078200    UP000005205    UP000002282    UP000008792    UP000192221    UP000075809    UP000078540    UP000001070    UP000000803    UP000091820    UP000078492    UP000078541    UP000001819    UP000008237   

PRIDE

H9JFD1    Q9VDZ8    C9QP57    Q8IHE3    Q9VDZ7   

Pfam

PF04280   Tim44        + More
PF01156   IU_nuc_hydro

Interpro

IPR032710   NTF2-like_dom_sf        + More
IPR039544   Tim44-like       
IPR017303   Tim44       
IPR007379   Tim44-like_dom       
IPR001910   Inosine/uridine_hydrolase_dom       
IPR036452   Ribo_hydro-like       

SUPFAM

SSF54427   SSF54427        + More
SSF53590   SSF53590       

Gene 3D

3.90.245.10    

ProteinModelPortal

H9JFD1   A0A2A4K8T8   A0A194QGT8   A0A194RIL8   A0A3S2P6Z3   A0A2H1VKH2   + More
A0A212EGQ1   A0A0L7LS41   A0A336LG68   A0A336LJM1   A0A023ES42   Q16YW1   Q16KX3   A0A182N1F8   A0A1B0CX04   A0A182YEY2   A0A182IQ97   A0A1L8DVE6   A0A182XBX3   A0A182QP74   A0A182MG14   A0A0K8V197   A0A1Q3F8U0   A0A182IAL1   A0A182VCZ9   A0A0A1WJA7   A0A034WTB6   A0A1J1ICR4   A0A1B6D3A0   Q7QF41   W8C6R9   A0A182RM84   A0A182TZG1   U5EHB1   W5JGB4   B0XGL1   K7J9V8   A0A182FNE5   A0A2M4AQW7   A0A182K2Y8   A0A0L0CLS3   A0A2M3Z9Y3   A0A2J7PNM9   A0A182VV88   A0A2P8YIH1   A0A084VJ49   A0A2M4BPI0   R4FJG7   A0A067QYX4   A0A182PV85   T1PIV4   A0A1I8P7L8   A0A1B6MUF4   A0A154PRU2   A0A088A218   A0A1B6I6N2   A0A1B6ID16   A0A1B6EPK7   A0A2A3EN09   A0A0A9Y9X4   A0A1A9Z8D4   A0A3B0KM66   A0A0L7QUG5   A0A151I734   A0A0M4F6I9   A0A232EJH0   A0A0M8ZZ16   A0A2R7VX32   D3TNU6   A0A0P8YHU2   A0A0Q9WZS4   B4IHY3   A0A1A9UYY1   A0A158NPU8   B3M1N4   A0A0R1E578   B4K5K9   B4LWF9   A0A1W4UPI4   A0A151X8M2   A0A0R1E0Y3   A0A1W4UBA7   A0A195ATU3   Q50LB5   B4JII9   Q9VDZ8   C9QP57   A0A0Q9WDY9   B4PMS2   A0A1A9WY78   A0A0K8TLC2   A0A1W4UMV1   A0A1W4UMN0   A0A195DTR5   A0A151JST3   Q8IHE3   Q9VDZ7   Q50LB6   A0A0R3NM32   E2BW71  

PDB

2CW9     E-value=7.5224e-65,     Score=628

KEGG

101743733    K17804 mitochondrial import inner membrane translocase subunit TIM44 | (RefSeq) mitochondrial import

GO

GO:0051087   GO:0005743   GO:0030150   GO:0015031   GO:0005623   GO:0071456   GO:0006626   GO:0015450   GO:0016787   GO:0005744   GO:0005488   GO:0005515   GO:0015992   GO:0005524   GO:0006811   GO:0005622   GO:0006810   GO:0003824  

PANTHER

PTHR10721  

Subcellular location

Mitochondrion inner membrane  

Length:

436

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00019

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00594

outside

1  -  436

 

 

Pi

181.546129

Theta

17.352915

Tajima's D

0.929384

CLR

0.289948

CSRT

0.649317534123294

Interpretation

Uncertain