Gene

KWMTBOMO11108  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008286

Annotation

PREDICTED:_tetraspanin_E118_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr18(-):13078925-13098115      View in EpiBrowser

Full name

Tetraspanin      

Location in the cell

PlasmaMembrane   Reliability : 4.684

CDS

ATGGGTTGCGGTGAATTTCTCGTGAAATATGTGCTTTTCTTTGCCAATTTAGCATTTGCGTTGGCAGGTCTCGCTCTGCTGGGCCTCGGATTGGCGGTTCATTTACAATTCGCTGACATAGAGACCGTTCTGTCAGAGACCAGCTTCAGGGTAGCGCCGGTGGCCTGTATGATTGTTGGAGGCATCGCATTCGTTATTGCGTTCTTCGGATGCTGCGGTGCCATCAGGGAGAGCAACTGCATGCTTGTCACCTACGCGATCTTCATGCTGGTGTTGATGGCACTGAAACTGACCTTGGGCGTAATGGTGTTTGTGAATCTCGACGGAGTAGTTGCTGCTATCCCGAACTGGATGAACAAGACCTTCCAGCAAGACCAAGATACGTTCCATGTCATCGAGCATAGATTCAGCTGCTGTGGTCCAACGGGTCCGGGCTCGTACCTATCCTTGACCCTGCCCATAACGTGCTGCTCGACGACCCCCTGTACGGTAATCAACGCGTACGCCGGCTGCACCGAAGTCCTGCAGGCACTCTTCAATAACTATGGCGTTGCTATCGGCTCTGTCGCCATCGTGATCGCCGCCATTGAAGTGGGCTGTGAGCTCGTCGATCCATCTAAGCAATAA

Protein

MGCGEFLVKYVLFFANLAFALAGLALLGLGLAVHLQFADIETVLSETSFRVAPVACMIVGGIAFVIAFFGCCGAIRESNCMLVTYAIFMLVLMALKLTLGVMVFVNLDGVVAAIPNWMNKTFQQDQDTFHVIEHRFSCCGPTGPGSYLSLTLPITCCSTTPCTVINAYAGCTEVLQALFNNYGVAIGSVAIVIAAIEVGCELVDPSKQ

Similarity

Belongs to the tetraspanin (TM4SF) family.

Feature

chain  Tetraspanin

Uniprot

Q1HQ39   H9JFI9   A0A2A4K899   A0A194RHI5   I4DPV3   A0A194QGK8   + More
A0A1E1W0A4   A0A3S2LT60   S4PF79   A0A212EGN7   A0A2H1WFM4   A0A2H1WF85   H9JNK5   A0A212EWY8   A0A067QYE5   A0A1E1W4P8   A0A1E1WV10   A0A3S2NM92   A0A2W1BPW8   S4PWL6   A0A2H1WW71   I4DJ82   Q9NB08   A0A2A4IYD2   A0A2J7QP49   I4DMY0   A0A1L8DKH3   A0A1L8DJJ6   U5EYJ6   A0A2A4K689   A0A194Q3K1   N6U6Y0   A0A2S2QPA1   A0A1I8MN26   A0A1I8QAH3   A0A2A3EHK8   V9IIY1   B3MHN0   A0A1L8EFG1   D6X1Y5   A0A087ZPN3   Q9NB07   Q2F647   Q2F648   Q29KL9   A0A0R3NZH4   B4GT52   A0A034WH04   A0A1B0GKM0   A0A0A1X8C6   E9J782   A0A0C9Q5P6   A0A084WER4   A0A0L7L5Y5   A0A139WBP1   A0A087TFG6   A0A1J1IM26   A0A232FLJ2   K7IST2   V5G3W6   R4WRU5  

Pubmed

19121390    26354079    22651552    23622113    22118469    24845553    + More
28756777    11122467    23537049    25315136    17994087    18362917    19820115    15632085    25348373    25830018    21282665    24438588    26227816    28648823    20075255    23691247   

EMBL

DQ443213    ABF51302.1    BABH01002470    BABH01002471    BABH01002472    NWSH01000032    + More
PCG80495.1    KQ460154    KPJ17288.1    AK403798    BAM19943.1    KQ458880    KPJ04637.1    GDQN01010636    JAT80418.1    RSAL01000264    RVE43294.1    GAIX01004167    JAA88393.1    AGBW02015051    OWR40653.1    ODYU01008292    SOQ51746.1    ODYU01008291    SOQ51745.1    BABH01035216    BABH01035217    BABH01035218    AGBW02011867    OWR45999.1    KK853109    KDR11258.1    GDQN01010381    GDQN01009120    JAT80673.1    JAT81934.1    GDQN01000423    JAT90631.1    RVE43295.1    KZ149990    PZC75605.1    GAIX01006573    JAA85987.1    ODYU01011526    SOQ57310.1    AK401350    BAM17972.1    AF274023    AAF90149.1    NWSH01005565    PCG64123.1    NEVH01012097    PNF30360.1    AK402648    BAM19270.1    GFDF01007244    JAV06840.1    GFDF01007446    JAV06638.1    GANO01000315    JAB59556.1    NWSH01000112    PCG79438.1    KQ459472    KPJ00118.1    APGK01047299    APGK01047300    KB741077    KB631602    ENN74342.1    ERL84575.1    GGMS01010157    MBY79360.1    KZ288246    PBC31188.1    JR049622    AEY61020.1    CH902619    EDV35866.1    GFDG01001496    JAV17303.1    KQ971371    EFA10185.1    AF274024    AAF90150.1    DQ311225    ABD36170.1    DQ311224    ABD36169.1    CH379061    EAL33155.3    KRT04783.1    CH479189    EDW25561.1    GAKP01005532    JAC53420.1    AJWK01030694    AJWK01030695    GBXI01007136    JAD07156.1    GL768424    EFZ11326.1    GBYB01009418    JAG79185.1    ATLV01023246    KE525341    KFB48708.1    JTDY01002812    KOB70674.1    KQ971372    KYB25323.1    KK114976    KFM63855.1    CVRI01000054    CRL00126.1    NNAY01000043    OXU31611.1    AAZX01003309    AAZX01016448    GALX01003741    JAB64725.1    AK417422    BAN20637.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000283053    UP000007151    + More
UP000027135    UP000235965    UP000019118    UP000030742    UP000095301    UP000095300    UP000242457    UP000007801    UP000007266    UP000005203    UP000001819    UP000008744    UP000092461    UP000030765    UP000037510    UP000054359    UP000183832    UP000215335    UP000002358   

PRIDE

Q1HQ39    H9JFI9    H9JNK5    Q2F647    Q2F648   

Pfam

PF00335   Tetraspanin

Interpro

IPR000301   Tetraspanin        + More
IPR018503   Tetraspanin_CS       
IPR018499   Tetraspanin/Peripherin       
IPR008952   Tetraspanin_EC2_sf       
IPR036259   MFS_trans_sf       

SUPFAM

SSF48652   SSF48652        + More
SSF103473   SSF103473       

Gene 3D

1.10.1450.10    

ProteinModelPortal

Q1HQ39   H9JFI9   A0A2A4K899   A0A194RHI5   I4DPV3   A0A194QGK8   + More
A0A1E1W0A4   A0A3S2LT60   S4PF79   A0A212EGN7   A0A2H1WFM4   A0A2H1WF85   H9JNK5   A0A212EWY8   A0A067QYE5   A0A1E1W4P8   A0A1E1WV10   A0A3S2NM92   A0A2W1BPW8   S4PWL6   A0A2H1WW71   I4DJ82   Q9NB08   A0A2A4IYD2   A0A2J7QP49   I4DMY0   A0A1L8DKH3   A0A1L8DJJ6   U5EYJ6   A0A2A4K689   A0A194Q3K1   N6U6Y0   A0A2S2QPA1   A0A1I8MN26   A0A1I8QAH3   A0A2A3EHK8   V9IIY1   B3MHN0   A0A1L8EFG1   D6X1Y5   A0A087ZPN3   Q9NB07   Q2F647   Q2F648   Q29KL9   A0A0R3NZH4   B4GT52   A0A034WH04   A0A1B0GKM0   A0A0A1X8C6   E9J782   A0A0C9Q5P6   A0A084WER4   A0A0L7L5Y5   A0A139WBP1   A0A087TFG6   A0A1J1IM26   A0A232FLJ2   K7IST2   V5G3W6   R4WRU5  

PDB

5TCX     E-value=2.93729e-07,     Score=127

KEGG

732926    K06497 CD63 antigen | (RefSeq) tetraspanin E118

PATHWAY

04142    Lysosome - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0045169   GO:0005887   GO:0003993   GO:0046872   GO:0046961   GO:0015992   GO:0005524   GO:0006811   GO:0005622   GO:0006810   GO:0003824  

Subcellular location

Membrane  

Length:

208

Number of predicted TMHs:

5

Exp number of AAs in TMHs:

109.80538

Exp number, first 60 AAs:

34.02666

Total prob of N-in:

0.99410

POSSIBLE N-term signal

sequence

inside

1  -  11

TMhelix

12  -  34

outside

35  -  48

TMhelix

49  -  71

inside

72  -  82

TMhelix

83  -  105

outside

106  -  147

TMhelix

148  -  170

inside

171  -  176

TMhelix

177  -  199

outside

200  -  208

 

 

Pi

257.808807

Theta

23.549967

Tajima's D

0.161779

CLR

139.182599

CSRT

0.425028748562572

Interpretation

Uncertain