Gene

KWMTBOMO11102

Pre Gene Modal

BGIBMGA008573

Annotation

PREDICTED:_poly(A)_RNA_polymerase?_mitochondrial_[Bombyx_mori]

Location

Bomo_Chr18(+):12996306-13001341      View in EpiBrowser

Full name

Poly(A) RNA polymerase, mitochondrial       + More
Aspartate aminotransferase      

Location in the cell

Nuclear   Reliability : 2.38

CDS

ATGTCTGTGTTATTTCAAAGTATAATAAATACTGGAAAACCTTATTCATTAAGACAAATAATCAGCAAATCTACAAGAATCTGCAAATGTTTCTCAAAAAGAAAATTTTCAGATATTTCAAGGAAGTTTTTATCATTTGATGAAGTCGCCGCGCAGAGAAGGGCTGAAGCAAAACGAAGTCTAGTCGTTCAAGTCAATTCAGAAGCATCTTTTAATGAATTGTACGGATATTGTTCTAAATATGCTTCCGTCAATGGTATACATCATTACAAAAATTCTGGAGACGAGCATTTTATGCTCATCGAGTTCAAAACTGAAGAAGAAAGTAAGAATGTCATACACTCCTGTAGCTCACATCAAAAAGATGTTGACGTTATGGCTTTACATTCACCATTTCTATGGTTCAGAGCAGTCTCAGGAAAGAAAGAAGCGTTTCAGATTCCTAAATCACAACTCATGACGACAAAAGGTTGTAATTCAATCGATGAAGATAACTTAATTGAAGAGTTAGCAAATTGTGAGGATGTGTCAGAACAAATTCAACAGATGCACGATAGGACAGCTTTGAATGATCTAGGTGTGAGATTGAGGTATATGGTAGCAAGGCAGATAGAAAGGATATTTGAGAGCCTGTATGCCAATATAGTTGTGAGACCATTCGGGTCATCTGTGAATGGTTTTGGAAAGATGGGCTGTGACTTAGACTTGGTGCTTACCAATATCCTGAATGAAGAAATGTGTGACTCATCAAAGAGATTGGTATATCAAGAGAAGAAGTGCGAAGGTGGTCGCAGTCCTTGGCAGCGACACATGGAGCTAGTTGGAGAATTGTTAGAACTAAGAGTGCCTGGTGCTACTAGAGTACAGAGGATACTGCATGCAAGAGTCCCCATTGTAAAATATGCCCATGAATTCACTGATGTTGATTGCGATCTTTGTTATAATAATATGTCTGGAGTATACATGTCAGAATTGCTTTGGCTCTACGGTTCTCTGGACCCCAGGGTTCGACCGCTCACATTTGTAGTCCGTCGATGGGCCCAAACAGTGGGCCTCACCAACCAACACCCTGGGCGGTGGATCACAAACTTCCCACTCACTTTGATGGTACTGTTCTTTCTCCAACAGAAAGGCAAGGATGGATGTGTTCTACCATCATTGAAAACTCTTGTTCAATATGCTGGAAAAGAAGATATTAGATTAGCAGAAGAGAATCTAAACTGTACATTCCTGAGAGATATGAATAAATTGCCAACGGACACGTACGGACAAAATAAAGCTAATCTAGAAACGTTACTGCTACAGTTTTTCGAGTTTTACGCTCAATTCGACTTTCATGACAAAGCTATATCGATTAACGAGGGGGTGGCTATACGAAAGCCAAACACTCTACCATTGTACATAGTGAATCCTTTAGAACAAGCCTTGAATGTTAGCCGGAATGTGAGTTACGAGGAGTGCGAGAGGTTGAAACTAGAGGTCCGCAACGCAGCGTGGCTGTTAGATGCAGGTTTGGATGGTAAGAAAACTGACGGGTGGGGCATATTGGGCCTTATTGAGAGAAAAAGCACCAGGGGCCTAAAAAATCTGCTGAAAGTAGGAAATTCACATCGGCTTGTCTCCGTGAAGGATTTATTCAACAACGATGATGACAAAATTGAGAAAGTGAAGGCGAAAAGAGATAGTGAAATGAAACAGGTGCTCGCTCAAGTTGATAATAAACCAAAGGAGAAAATTAAGTTCAAGAACACGCAAGTTGCTAGTGAAGTTTATAGGATACGTAGGGATAAAATTATATGA

Protein

MSVLFQSIINTGKPYSLRQIISKSTRICKCFSKRKFSDISRKFLSFDEVAAQRRAEAKRSLVVQVNSEASFNELYGYCSKYASVNGIHHYKNSGDEHFMLIEFKTEEESKNVIHSCSSHQKDVDVMALHSPFLWFRAVSGKKEAFQIPKSQLMTTKGCNSIDEDNLIEELANCEDVSEQIQQMHDRTALNDLGVRLRYMVARQIERIFESLYANIVVRPFGSSVNGFGKMGCDLDLVLTNILNEEMCDSSKRLVYQEKKCEGGRSPWQRHMELVGELLELRVPGATRVQRILHARVPIVKYAHEFTDVDCDLCYNNMSGVYMSELLWLYGSLDPRVRPLTFVVRRWAQTVGLTNQHPGRWITNFPLTLMVLFFLQQKGKDGCVLPSLKTLVQYAGKEDIRLAEENLNCTFLRDMNKLPTDTYGQNKANLETLLLQFFEFYAQFDFHDKAISINEGVAIRKPNTLPLYIVNPLEQALNVSRNVSYEECERLKLEVRNAAWLLDAGLDGKKTDGWGILGLIERKSTRGLKNLLKVGNSHRLVSVKDLFNNDDDKIEKVKAKRDSEMKQVLAQVDNKPKEKIKFKNTQVASEVYRIRRDKII

Description

Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. This is not required for transcript stability or translation but may maintain mRNA integrity by protecting 3' termini from degradation.

Catalytic Activity

ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide
2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate

Subunit

Homodimer.

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

Similarity

Belongs to the DNA polymerase type-B-like family.

Keywords

ATP-binding   Complete proteome   Magnesium   Manganese   Metal-binding   Mitochondrion   mRNA processing   Nucleotide-binding   Nucleotidyltransferase   Reference proteome   RNA-binding   Transferase   Transit peptide  

Feature

chain  Poly(A) RNA polymerase, mitochondrial

Uniprot

H9JGC6   A0A2H1V5H0   A0A194RIM7   A0A194QGL1   A0A0L7LS96   U5ES50   + More
B4GTN0   Q29IZ3   D6WRJ4   N6UHN1   U4UI64   A0A0K8U570   A0A3B0JW34   A0A1A9WCN3   A0A1W4VES3   B4PXN3   A0A034WU74   B4N1T4   W8C4A9   W8BIL5   A0A0A1X914   A0A0T6AVL1   B3MRE7   A0A1B0FFX7   A0A1A9VCS1   A0A1I8MY71   O46102   A0A1A9ZER3   T1PJZ1   B4L3W0   A0A0L0CP49   A0A1Y1L0P9   B4JLB0   A0A1A9XBM5   A0A1B0ATF2   B3P9G5   B4M3J7   A0A1I8PNX8   J9K7W6   A0A067QQB6   A0A2S2NMM5   B0W498   K7IRY0   A0A1S4EXH1   A0A336MLC6   A0A182VQL9   Q17MJ9   A0A336N5X3   A0A182MMM3   A0A2H8TGA2   A0A1S4GI68   A0A182X1Y7   A0A182RHY0   A0A182HJF5   A0A1B6MF47   A0A182TGJ3   A0A182UWT2   A0A1Q3F3W0   A0A182HDM3   Q7Q0J0   A0A336LRV6   A0A182YK94   A0A182JSN4   A0A182P5R6   A0A1J1HJX9   A0A182INP7   A0A1B0CAQ6   A0A182NL64   A0A1B0DAF9   W5J3W8   A0A2S2QAC1   A0A1S4EPJ9   A0A3Q0JG48   A0A182FQP7   A0A182QS77   A0A1B6EP16   A0A084VQL3   F4WXD2   A0A182LCR8   A0A158NKT9   E2C3E6   A0A151IS06   E9ICS1   A0A151X8B2   A0A1B6CKY0   A0A0V0GB48   A0A023ETY7   E2ALG8   A0A0A9ZGE8   A0A023F1M2   A0A195CYI5   A0A195F541   A0A3L8DT43   A0A026VZ68  

EC Number

2.7.7.19
2.6.1.1

Pubmed

19121390    26354079    26227816    17994087    15632085    18362917    + More
19820115    23537049    17550304    25348373    24495485    25830018    25315136    10731137    10731132    12537572    12537569    27176048    26108605    28004739    24845553    20075255    17510324    12364791    26483478    25244985    20920257    23761445    24438588    21719571    20966253    21347285    20798317    21282665    24945155    25401762    25474469    30249741    24508170   

EMBL

BABH01002463    ODYU01000763    SOQ36039.1    KQ460154    KPJ17294.1    KQ458880    + More
KPJ04642.1    JTDY01000200    KOB78322.1    GANO01003406    JAB56465.1    CH479190    EDW25900.1    CH379063    EAL32510.3    KQ971351    EFA06440.1    APGK01019954    KB740150    ENN81250.1    KB632173    ERL89575.1    GDHF01030603    JAI21711.1    OUUW01000011    SPP86264.1    CM000162    EDX00886.1    GAKP01001232    JAC57720.1    CH963925    EDW78323.2    GAMC01009691    JAB96864.1    GAMC01009692    JAB96863.1    GBXI01006513    JAD07779.1    LJIG01022704    KRT79145.1    CH902622    EDV34352.2    CCAG010008264    AL022018    AE014298    AY119282    BT132966    AAM51142.1    AEW48257.1    CAA17688.2    KA648979    AFP63608.1    CH933810    EDW07238.1    JRES01000104    KNC34110.1    GEZM01068036    JAV67249.1    CH916370    EDW00363.1    JXJN01003292    CH954183    EDV45461.1    CH940651    EDW65372.1    ABLF02034857    KK853582    KDR06507.1    GGMR01005583    MBY18202.1    DS231836    EDS33183.1    UFQT01001585    SSX31066.1    CH477205    EAT47925.1    UFQT01002692    SSX33948.1    AXCM01001179    GFXV01001274    MBW13079.1    AAAB01008794    AAAB01008982    APCN01002160    GEBQ01005462    JAT34515.1    GFDL01012801    JAV22244.1    JXUM01129974    KQ567517    KXJ69395.1    EAA14654.4    UFQS01004354    UFQT01004354    SSX16342.1    SSX35661.1    CVRI01000004    CRK87716.1    AJWK01004158    AJVK01013292    ADMH02002181    ETN58018.1    GGMS01005277    MBY74480.1    AXCN02000083    GECZ01030166    JAS39603.1    ATLV01015250    KE525004    KFB40257.1    GL888424    EGI61098.1    ADTU01002130    GL452320    EFN77484.1    KQ981102    KYN09461.1    GL762354    EFZ21622.1    KQ982431    KYQ56550.1    GEDC01023260    JAS14038.1    GECL01000801    JAP05323.1    GAPW01001237    JAC12361.1    GL440607    EFN65726.1    GBHO01000468    JAG43136.1    GBBI01003818    JAC14894.1    KQ977110    KYN05718.1    KQ981805    KYN35578.1    QOIP01000005    RLU22938.1    KK107570    EZA48761.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000037510    UP000008744    UP000001819    + More
UP000007266    UP000019118    UP000030742    UP000268350    UP000091820    UP000192221    UP000002282    UP000007798    UP000007801    UP000092444    UP000078200    UP000095301    UP000000803    UP000092445    UP000009192    UP000037069    UP000001070    UP000092443    UP000092460    UP000008711    UP000008792    UP000095300    UP000007819    UP000027135    UP000002320    UP000002358    UP000075920    UP000008820    UP000075883    UP000076407    UP000075900    UP000075840    UP000075902    UP000075903    UP000069940    UP000249989    UP000007062    UP000076408    UP000075881    UP000075885    UP000183832    UP000075880    UP000092461    UP000075884    UP000092462    UP000000673    UP000079169    UP000069272    UP000075886    UP000030765    UP000007755    UP000075882    UP000005205    UP000008237    UP000078492    UP000075809    UP000000311    UP000078542    UP000078541    UP000279307    UP000053097   

PRIDE

H9JGC6    O46102   

Pfam

PF03828   PAP_assoc        + More
PF17797   RL
PF01909   NTP_transf_2
PF00155   Aminotran_1_2
PF01408   GFO_IDH_MocA
PF09230   DFF40
PF02017   CIDE-N

Interpro

IPR002058   PAP_assoc        + More
IPR041252   RL       
IPR035979   RBD_domain_sf       
IPR002934   Polymerase_NTP_transf_dom       
IPR015421   PyrdxlP-dep_Trfase_major       
IPR015311   DFF40_C       
IPR004839   Aminotransferase_I/II       
IPR015424   PyrdxlP-dep_Trfase       
IPR000683   Oxidoreductase_N       
IPR000796   Asp_trans       
IPR036291   NAD(P)-bd_dom_sf       
IPR003508   CIDE-N_dom       
IPR004838   NHTrfase_class1_PyrdxlP-BS       
IPR015422   PyrdxlP-dep_Trfase_dom1       
IPR012677   Nucleotide-bd_a/b_plait_sf       

SUPFAM

SSF54928   SSF54928        + More
SSF53383   SSF53383       
SSF51735   SSF51735       

Gene 3D

3.40.640.10     3.90.1150.10     3.30.70.330    

ProteinModelPortal

H9JGC6   A0A2H1V5H0   A0A194RIM7   A0A194QGL1   A0A0L7LS96   U5ES50   + More
B4GTN0   Q29IZ3   D6WRJ4   N6UHN1   U4UI64   A0A0K8U570   A0A3B0JW34   A0A1A9WCN3   A0A1W4VES3   B4PXN3   A0A034WU74   B4N1T4   W8C4A9   W8BIL5   A0A0A1X914   A0A0T6AVL1   B3MRE7   A0A1B0FFX7   A0A1A9VCS1   A0A1I8MY71   O46102   A0A1A9ZER3   T1PJZ1   B4L3W0   A0A0L0CP49   A0A1Y1L0P9   B4JLB0   A0A1A9XBM5   A0A1B0ATF2   B3P9G5   B4M3J7   A0A1I8PNX8   J9K7W6   A0A067QQB6   A0A2S2NMM5   B0W498   K7IRY0   A0A1S4EXH1   A0A336MLC6   A0A182VQL9   Q17MJ9   A0A336N5X3   A0A182MMM3   A0A2H8TGA2   A0A1S4GI68   A0A182X1Y7   A0A182RHY0   A0A182HJF5   A0A1B6MF47   A0A182TGJ3   A0A182UWT2   A0A1Q3F3W0   A0A182HDM3   Q7Q0J0   A0A336LRV6   A0A182YK94   A0A182JSN4   A0A182P5R6   A0A1J1HJX9   A0A182INP7   A0A1B0CAQ6   A0A182NL64   A0A1B0DAF9   W5J3W8   A0A2S2QAC1   A0A1S4EPJ9   A0A3Q0JG48   A0A182FQP7   A0A182QS77   A0A1B6EP16   A0A084VQL3   F4WXD2   A0A182LCR8   A0A158NKT9   E2C3E6   A0A151IS06   E9ICS1   A0A151X8B2   A0A1B6CKY0   A0A0V0GB48   A0A023ETY7   E2ALG8   A0A0A9ZGE8   A0A023F1M2   A0A195CYI5   A0A195F541   A0A3L8DT43   A0A026VZ68  

PDB

5A2Z     E-value=1.34017e-69,     Score=670

KEGG

101737642    K18060 poly(A) RNA polymerase, mitochondrial [EC:2.7.7.19] | (RefSeq) poly(A) RNA polymerase, mitoch

GO

GO:0003676   GO:0097222   GO:1990817   GO:0005739   GO:0036416   GO:0016779   GO:0046872   GO:0006378   GO:0003723   GO:0005524   GO:0016491   GO:0016787   GO:0006309   GO:0004069   GO:0009058   GO:0005737   GO:0030170   GO:0005634   GO:0006520  

PANTHER

PTHR11879  

Subcellular location

Mitochondrion  

Length:

599

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01676

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00062

outside

1  -  599

 

 

Pi

24.438812

Theta

155.976042

Tajima's D

-0.818608

CLR

265.726318

CSRT

0.170091495425229

Interpretation

Uncertain