Gene

KWMTBOMO11064  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008551

Annotation

PREDICTED:_hypoxia_up-regulated_protein_1_[Papilio_polytes]

Location

Bomo_Chr18(+):11553555-11561401      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.735 ER   Reliability : 1.356

CDS

ATGTATAGTGTGTTGTGTGTGGTGTTATTGCCGATACTTTTAAGCCAACAAGTCGATGCGGCGGCAGTAATTTCCATTGATTTTGGATCAGAATGGATGAAGGTTGGCATAGTGTCACCGGGTGTTCCTATGGAAATCGTGTTGAACAAGGAGTCTAAGAGGAAGACACCAGCTGTCGTTGCCTTCAGAGATGATGTTCGGACATTCGGGGAAGATGCTGTGACAGTTGGAGTCAGATTCCCTAAAAATTCCTACAAATATTTACTTGAACTTCTTGGCAAGACATATGACCACCCTCTTGTACAATTATTCAGAAAGAGGTTCCCTTATTATGAAATTGTGGAATCGGACCGAGGCACAATTGAATTTGTGCATGATGACAAGACAAAATTTACACCTGAAGAGCTAGTTGCACAGATTCTAGCCAAAGCCAAAGATTTTGCTGAAATTAATCATGGCCAACAGATTAGCGAGTGTGTGATTACAGTTCCTGGTTACTTTAATCAGGCTGAGCGTAGAGCACTCAAAGAAGCTGCTTCATTAGCAGGCTTGAATGTTTTGCAGTTAATTAATGATTATACTGCTATTGCTATCAACTATGGCATATTTAGGAGAAAGGAAATCAATGAAACCGCATGGTACACTTTGTTCTTTGATATGGGAGCATCTTCGACTAAAGCCGCATTAGTTGAATATAAAACTGTCAAAATTAAGGACAAGGGTTATGTTGAAACTGTGCCACAACTGCAGGTCTTAGGTGTTGGTTTTGACAGAACACTTGGAGGTTTAGAAATGACGCTTCGTCTCCGCGAGCATCTGATTAAAGCCTGGGAGGCTAACGGGGGAGGCGATGTGCGAGCGTCACCTCGTGCTATGGAGAAACTGTTCCGCGAGGCGGAAAGGCTAAAGGTCGTGCTCTCTGCTAACACCGAGTTCTACGCTCAAATTGAAAGCCTTCTTGATGACAAAGACTTCAAGCTGCAGGTGAGCAGGGCTGAGCTGGAAGAGTTATGTGCTGACCTCTGGGCGCGGGTGGGGGCGGTGGTGCGGCGCGCGGTGTCGGCGGCGGGGGGCGCGGGGGCGGGCGCGCGGCTGGTGGTGGCGGGGGGCGGGTCGCGCGTGCCCGCCGTGCTGGCCGCGCTCGCCGACGCGGTGCAGCACGAGCCCGCGCGCTCCATCAACGCGGACGAGGCTGCCACTCTCGGAGCTGTCTACAGAGCGGCATCATTAGCAACAGGATACAAAGTGGCCCCTCTGAATGTACGAGATGCTGTGTTGCTTCCAATACAAGTTGTCTTCACAAGACACGCCGATGGCGTCGACAAGCTGGTTAAGAGAACTCTCTTTGGGCCTATGAACCCCTACCCACAGAAGAAGGTGATCACTTTCAATAAGCACACAGAGGATTTCTCCTTCAACGTGAACTATGCAGAACTTGATCACATCCCATCCACTGAATTGCAGTACATTGGTGCTCTGAACTTGAGTGAGGTTTCGTTGAGTGGAGTTTCCGCGGCTTTGGGTAAACATGTTGGCGAAAATGTCGAACATAAAGGTATTAAGGCACATTTCAATATGGACGACTCCGGCATACTAAACTTGGTTAACGTTGAATTTGTTGCTGAGAAGACCGTCACAGAAGACGAAGACAAAGATAGCACTCTGTCTAAGATCGGAAGTACTATTAGTAAATTATTTGGTTCAGATTCAGAAACTCCGGAAAAAACTGAAGAACAACCCCAGGGAGAAGCTAAGAACGATACACAGAATCTCAACGAGACGACCACTGATAAGCAGAATTCAACAGAAACTGACAGCAAACCTAAACCGAAAATCGTTATTTTGAAAGAACCAATTAAATCCGAAGAATTAGTCCTCAACTTGCAGCCTCTGTCAACCGACCAGTTCAAGAATTCGAAAGCAAAGATAAATGAACTAAACACGATCGACAAGAAGCGTGTCCAAAGAGAAACGGCGTTGAATAATCTCGAAGCGTTCGTTGTTGACGCCCAAATGAAGATCGACATGGAGGAGTATGCTGAATGTGGAACTGAGGAGGAAATTGAGGAGATCCGTAAACTGTGCAGCGAGACTTCCGAATGGTTATACGATGATGGATACGATGCAGACACTGAACTGTTCGAACAAAAACTTAATGCTCTTAAAGAAAAAACTCATCCCATATTCTACAAGCATTGGGAACACAGAGAAAGGGCGGACGCGGTTGCAGCGATTCGAAACTTATTGAATAGTTCTAAGGAATTCCTTAAAATGTCAAAGAACTTCACCAAAGAGTCGAATGAAGAGAAAGATGTCTTTACCGAAGTTGAGATTGGCGTTTTAGAAAAGAAGATCGAGGAAACTGAGACTTGGCTAGAGAAGGCCATCAAAGAACAAAAGGCACTGAAAAAGAACGAAGACGTTAAATTGACAGTTGACAGCATTCGAGAAAAAATGGCAAATCTCGACAGAGAAGTAAAGTATTTGTTGAACAAAATGAAGATTTGGCGACCCAAGAAACCAGTCAAGAAAGATGCAGATAATAAAACCGAGGAAGTCGTGATAGAGCCTCCAGAGAATCCCGAGACTCAGGAGGAGGCTCCTCAAGATGATAGCGGTGCTGATGATAAACCAGAAGAAGAGGTTAAAGAGATGGACGCTAAAGAAGAATCAACAGAGCCACCCCTACAGCTCTCTGACGGTCAAGCTGAACATTCCGAGTTATAA

Protein

MYSVLCVVLLPILLSQQVDAAAVISIDFGSEWMKVGIVSPGVPMEIVLNKESKRKTPAVVAFRDDVRTFGEDAVTVGVRFPKNSYKYLLELLGKTYDHPLVQLFRKRFPYYEIVESDRGTIEFVHDDKTKFTPEELVAQILAKAKDFAEINHGQQISECVITVPGYFNQAERRALKEAASLAGLNVLQLINDYTAIAINYGIFRRKEINETAWYTLFFDMGASSTKAALVEYKTVKIKDKGYVETVPQLQVLGVGFDRTLGGLEMTLRLREHLIKAWEANGGGDVRASPRAMEKLFREAERLKVVLSANTEFYAQIESLLDDKDFKLQVSRAELEELCADLWARVGAVVRRAVSAAGGAGAGARLVVAGGGSRVPAVLAALADAVQHEPARSINADEAATLGAVYRAASLATGYKVAPLNVRDAVLLPIQVVFTRHADGVDKLVKRTLFGPMNPYPQKKVITFNKHTEDFSFNVNYAELDHIPSTELQYIGALNLSEVSLSGVSAALGKHVGENVEHKGIKAHFNMDDSGILNLVNVEFVAEKTVTEDEDKDSTLSKIGSTISKLFGSDSETPEKTEEQPQGEAKNDTQNLNETTTDKQNSTETDSKPKPKIVILKEPIKSEELVLNLQPLSTDQFKNSKAKINELNTIDKKRVQRETALNNLEAFVVDAQMKIDMEEYAECGTEEEIEEIRKLCSETSEWLYDDGYDADTELFEQKLNALKEKTHPIFYKHWEHRERADAVAAIRNLLNSSKEFLKMSKNFTKESNEEKDVFTEVEIGVLEKKIEETETWLEKAIKEQKALKKNEDVKLTVDSIREKMANLDREVKYLLNKMKIWRPKKPVKKDADNKTEEVVIEPPENPETQEEAPQDDSGADDKPEEEVKEMDAKEESTEPPLQLSDGQAEHSEL

Similarity

Belongs to the heat shock protein 70 family.

Uniprot

H9JGA4   A0A1L6UW57   A0A3S2NMB7   A0A2A4J222   A0A2H1WD30   A0A194PGL6   + More
A0A212FA98   S4NXF8   A0A194RIS5   A0A1W4WWZ7   A0A1Y1M3G5   A0A0T6BHH0   D2A1Y3   N6TRK0   U4UKB7   A0A067RL26   J9HG73   A0A1S4G5N6   A0A1L8DU22   U5EW42   A0A2J7PUI5   A0A2J7PUJ5   A0A023EWK4   A0A182PR32   A0A182Q0R7   A0A1W7R800   A0A182K425   A0A182JHS1   A0A232FLN9   A0A182YJX8   A0A182N4Y7   A0A1Q3FAB9   A0A1Q3FAL8   K7INW6   A0A182SXE1   A0A1Q3FA24   A0A2M3YYX7   A0A1Q3F9W9   A0A2M3YYQ4   A0A224XE47   A0A0N0BIV3   A0A182MPB6   B0WKR8   A0A182F6X2   A0A2M4BCA9   A0A084VRQ9   A0A411G6N6   A0A2M3YYW3   A0A2M3ZZN5   Q7PYB0   A0A154P7S5   A0A2M3ZZS3   A0A0K8TS50   A0A182I0I9   A0A2M3ZZM4   A0A0L7RI19   A0A182RBY4   A0A182X2N8   A0A182UQ00   A0A146LN42   W5JLW0   A0A1I9WL37   A0A2M4CGB0   A0A0C9QZD6   A0A0P4VS14   V9ILC7   A0A088ARD8   A0A2K8JV05   R4WQM8   A0A182VQU5   A0A0A1XB50   A0A1B6CKK6   A0A1W6EWB4   B4L5V3   A0A1S4N1I5   E0W3D7   W8C075   E2C858   A0A336K1X8   A0A336LJS3   B4M7E2   A0A182U555   A0A034VS83   A0A0K8UUM5   B4R3H2   A0A0M4EUQ0   A0A0C9RPQ7   O46067   B4I9T7   A0A1W4UPT9   B4Q175   F4W487   B3P902   A0A0Q5T728   A0A195E5K9   A0A195ET77   A0A1J1HJA8   A0A026VV58   A0A195CJL8   A0A1I8PTD8  

Pubmed

19121390    26354079    22118469    23622113    28004739    18362917    + More
19820115    23537049    24845553    17510324    24945155    28648823    25244985    20075255    24438588    12364791    14747013    17210077    26369729    26823975    20920257    23761445    27538518    27129103    23691247    25830018    17994087    20566863    24495485    20798317    25348373    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    21719571    24508170    30249741   

EMBL

BABH01002326    KY379955    APS85765.1    RSAL01000035    RVE51320.1    NWSH01003698    + More
PCG65909.1    ODYU01007832    SOQ50937.1    KQ459604    KPI92447.1    AGBW02009508    OWR50650.1    GAIX01012192    JAA80368.1    KQ460154    KPJ17240.1    GEZM01042808    JAV79578.1    LJIG01000319    KRT86621.1    KQ971338    EFA02143.1    APGK01022393    APGK01022394    KB740420    ENN80698.1    KB632390    ERL94524.1    KK852450    KDR23698.1    CH477636    EJY57847.1    GFDF01004158    JAV09926.1    GANO01000723    JAB59148.1    NEVH01021197    PNF19992.1    PNF19993.1    GAPW01000140    JAC13458.1    AXCN02000185    GEHC01000379    JAV47266.1    NNAY01000039    OXU31666.1    GFDL01010545    JAV24500.1    GFDL01010429    JAV24616.1    GFDL01010611    JAV24434.1    GGFM01000667    MBW21418.1    GFDL01010674    JAV24371.1    GGFM01000653    MBW21404.1    GFTR01008358    JAW08068.1    KQ435726    KOX78218.1    AXCM01005541    DS231975    EDS30010.1    GGFJ01001516    MBW50657.1    ATLV01015768    KE525036    KFB40653.1    MH365729    QBB01538.1    GGFM01000695    MBW21446.1    GGFK01000692    MBW34013.1    AAAB01008987    EAA01085.3    KQ434825    KZC07374.1    GGFK01000678    MBW33999.1    GDAI01000424    JAI17179.1    APCN01002086    GGFK01000676    MBW33997.1    KQ414584    KOC70637.1    GDHC01010024    JAQ08605.1    ADMH02001196    ETN63764.1    KU932221    APA33857.1    GGFL01000202    MBW64380.1    GBYB01009159    GBYB01009163    JAG78926.1    JAG78930.1    GDKW01001229    JAI55366.1    JR050456    AEY61286.1    KY031144    ATU82895.1    AK417986    BAN21201.1    GBXI01006282    JAD08010.1    GEDC01027149    GEDC01023413    GEDC01018485    GEDC01006718    GEDC01003827    JAS10149.1    JAS13885.1    JAS18813.1    JAS30580.1    JAS33471.1    KY563607    ARK20016.1    CH933811    EDW06562.1    AAZO01007370    DS235882    EEB20143.1    GAMC01007544    JAB99011.1    GL453568    EFN75861.1    UFQS01000021    UFQT01000021    SSW97518.1    SSX17904.1    SSW97519.1    SSX17905.1    CH940653    EDW62709.1    GAKP01012796    JAC46156.1    GDHF01022259    GDHF01007732    JAI30055.1    JAI44582.1    CM000366    EDX16924.1    CP012528    ALC49526.1    GBYB01009161    JAG78928.1    AE014298    AY094705    AL009196    AAF45769.1    AAM11058.1    ACZ95182.1    CAA15711.1    CH480825    EDW43968.1    CM000162    EDX01382.1    KRK06132.1    KRK06133.1    KRK06134.1    GL887491    EGI71083.1    CH954183    EDV45607.2    KQS26036.1    KQ979609    KYN20182.1    KQ981979    KYN31455.1    CVRI01000006    CRK88111.1    KK107796    QOIP01000013    EZA47658.1    RLU15578.1    KQ977642    KYN00925.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000053268    UP000007151    UP000053240    + More
UP000192223    UP000007266    UP000019118    UP000030742    UP000027135    UP000008820    UP000235965    UP000075885    UP000075886    UP000075881    UP000075880    UP000215335    UP000076408    UP000075884    UP000002358    UP000075901    UP000053105    UP000075883    UP000002320    UP000069272    UP000030765    UP000007062    UP000076502    UP000075840    UP000053825    UP000075900    UP000076407    UP000075903    UP000000673    UP000005203    UP000075920    UP000009192    UP000009046    UP000008237    UP000008792    UP000075902    UP000000304    UP000092553    UP000000803    UP000001292    UP000192221    UP000002282    UP000007755    UP000008711    UP000078492    UP000078541    UP000183832    UP000053097    UP000279307    UP000078542    UP000095300   

PRIDE

H9JGA4    O46067   

Pfam

PF00012   HSP70        + More
PF10390   ELL
PF07303   Occludin_ELL

Interpro

IPR018181   Heat_shock_70_CS        + More
IPR029048   HSP70_C_sf       
IPR029047   HSP70_peptide-bd_sf       
IPR013126   Hsp_70_fam       
IPR009062   Smac/DIABLO-like_sf       
IPR019464   ELL_N       
IPR010844   Occludin_ELL       
IPR036390   WH_DNA-bd_sf       
IPR042065   E3_ELL-like       

SUPFAM

SSF100934   SSF100934        + More
SSF46984   SSF46984       
SSF46785   SSF46785       

Gene 3D

1.20.1270.10     2.60.34.10     1.10.10.2670    

ProteinModelPortal

H9JGA4   A0A1L6UW57   A0A3S2NMB7   A0A2A4J222   A0A2H1WD30   A0A194PGL6   + More
A0A212FA98   S4NXF8   A0A194RIS5   A0A1W4WWZ7   A0A1Y1M3G5   A0A0T6BHH0   D2A1Y3   N6TRK0   U4UKB7   A0A067RL26   J9HG73   A0A1S4G5N6   A0A1L8DU22   U5EW42   A0A2J7PUI5   A0A2J7PUJ5   A0A023EWK4   A0A182PR32   A0A182Q0R7   A0A1W7R800   A0A182K425   A0A182JHS1   A0A232FLN9   A0A182YJX8   A0A182N4Y7   A0A1Q3FAB9   A0A1Q3FAL8   K7INW6   A0A182SXE1   A0A1Q3FA24   A0A2M3YYX7   A0A1Q3F9W9   A0A2M3YYQ4   A0A224XE47   A0A0N0BIV3   A0A182MPB6   B0WKR8   A0A182F6X2   A0A2M4BCA9   A0A084VRQ9   A0A411G6N6   A0A2M3YYW3   A0A2M3ZZN5   Q7PYB0   A0A154P7S5   A0A2M3ZZS3   A0A0K8TS50   A0A182I0I9   A0A2M3ZZM4   A0A0L7RI19   A0A182RBY4   A0A182X2N8   A0A182UQ00   A0A146LN42   W5JLW0   A0A1I9WL37   A0A2M4CGB0   A0A0C9QZD6   A0A0P4VS14   V9ILC7   A0A088ARD8   A0A2K8JV05   R4WQM8   A0A182VQU5   A0A0A1XB50   A0A1B6CKK6   A0A1W6EWB4   B4L5V3   A0A1S4N1I5   E0W3D7   W8C075   E2C858   A0A336K1X8   A0A336LJS3   B4M7E2   A0A182U555   A0A034VS83   A0A0K8UUM5   B4R3H2   A0A0M4EUQ0   A0A0C9RPQ7   O46067   B4I9T7   A0A1W4UPT9   B4Q175   F4W487   B3P902   A0A0Q5T728   A0A195E5K9   A0A195ET77   A0A1J1HJA8   A0A026VV58   A0A195CJL8   A0A1I8PTD8  

PDB

3JXU     E-value=3.13658e-42,     Score=436

KEGG

101746297    K09486 hypoxia up-regulated 1 | (RefSeq) hypoxia up-regulated protein 1

PATHWAY

04141    Protein processing in endoplasmic reticulum - Bombyx mori (domestic silkworm)

GO

GO:0005524   GO:0005783   GO:0034663   GO:0071456   GO:1903298   GO:0016021   GO:0006919   GO:0005739   GO:0006915   GO:0005615   GO:0032440   GO:0012505   GO:0032504   GO:0008023   GO:0006368  

SignalP

Position:   1 - 20,         Likelihood:  0.998330

 

 

Length:

908

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.899729999999999

Exp number, first 60 AAs:

0.86727

Total prob of N-in:

0.04069

outside

1  -  908

 

 

Pi

213.964572

Theta

169.194017

Tajima's D

0.536425

CLR

0.781154

CSRT

0.526823658817059

Interpretation

Uncertain