Gene

KWMTBOMO11042

Annotation

chymotrypsin-like_serine_protease_precursor_[Bombyx_mori]

Location

Bomo_Chr18(-):10780009-10785463      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 2.003 PlasmaMembrane   Reliability : 2.653

CDS

ATGAAAACTGCTGTACTCTTCGGTATCTTCTTCGTGGGCTACACATCAGCCTATGTGCCGGTGGAGACCTTCTACCACGAGAATGTGGGAATACCCCTAGCTAAAAGTATTAGGGCTGCGGAGACTGCAAAGCTTGACTCAAGTGTCCAGCCAGACAATGCTGCAAGGATAGTTGGTGGGGCCATTTCGCCATCAAACGCACATCCTTATTTGGCTGGTCTTCTCATCACCTTCATAAACGCCGTCGGTACTTCGGCGTGTGGATCATCGCTTCTTTCAGCTAACAGGCTAGTCACCGCCGCCCACTGCTGGTTTGATGGCCGCTTCCAAGCTAACCAGTTCGTTGTGGTTCTCGGCTCAAACACGCTGTTCCACGGTGGTGTTCGTGTCACTACTCGTCAAGTTTTTGTACATCCTCAATGGAATCCCACCCTTTTGAACAACGATGTGGCAATGATTTACCTACCTCACAGGGTTACTCTGAACAACAACATCAAGCCCATCGCTCTGCCTAACACCGCCGATTTGAACAACCTATTTGTTGGCCAATGGGCGGTCGCTGCTGGATATGGATTAACTAGTGACGCGCAAACTGGTATCTCGGTAAATCAGGTGATGAGCCAAGTGAACCTGCAAGTGATCACAGTGCAACAGTGCATGGCCGTTTTCGGTAGCAACTTCGTGAGGAACTCAAACATCTGCACGAACGGAGCTGGCGGTGTCGGTATTTGCCGCGGAGACTCCGGCGGACCACTTTTGTTGAACCGTAATGGTGTACTAACCTTAATCGGTATCAGTTCTTTCGTAGCCCAGAACAGATGCCAGGACGGATTCCCATCTGCCTTCGCCAGAGTTACAAGTTTCAACAATTTCATCCGCCAGCATTTATAA

Protein

MKTAVLFGIFFVGYTSAYVPVETFYHENVGIPLAKSIRAAETAKLDSSVQPDNAARIVGGAISPSNAHPYLAGLLITFINAVGTSACGSSLLSANRLVTAAHCWFDGRFQANQFVVVLGSNTLFHGGVRVTTRQVFVHPQWNPTLLNNDVAMIYLPHRVTLNNNIKPIALPNTADLNNLFVGQWAVAAGYGLTSDAQTGISVNQVMSQVNLQVITVQQCMAVFGSNFVRNSNICTNGAGGVGICRGDSGGPLLLNRNGVLTLIGISSFVAQNRCQDGFPSAFARVTSFNNFIRQHL

Similarity

Belongs to the peptidase S1 family.

Uniprot

Q1HPW8   A0A3S2NMC5   A0A1B1LTR9   A0A3S2LDG1   I6TMX9   I6SJ44   + More
A0A0L7LI04   A0A2H1X112   A0A1E1W2N0   A0A1E1WL73   A0A194PHE1   A0A1E1WB13   A0A0N0PBU1   A0A0M4MQT7   A0A1E1WTE4   A0A2A4JK09   A0A2A4JJ19   A0A1E1WDT0   A0A089Q9M9   A0A2A4JJV5   A0A2H1X2D3   A0A212F096   A0A2A4JJQ3   C9W8J3   E0W9N7   C9W8G2   C9W8H9   A0A2A4JIX9   A0A2A4JKX6   C9W8G9   A0A0M5KXW7   A0A194PHC5   E7D016   A0A194R1N4   A0A1E1WJ19   J7FDD9   A0A089QAL5   A0A0K8SR13   A0A089QDB8   A0A2W1BWV2   C9W8J4   A0A2H1V6W6   A0A2A4K0B4   Q2F617   A0PGD5   A0A194Q0R8   J7FCZ4   A0A2A4JFK9   J7FDV8   A0A0N1PGY7   O18438   C9W8F5   A0A2H1V7A9   Q9NGY4   A0A2H1V6P6   A0A089RSY0   H9JG67   O18444   C7FF06   A0A2H1WCW9   A0A2W1BAG4   O18450   A0A2A4JFM8   A0PGD4   Q9NH07   E7D003   C9W8G3   A0A2A4K202   A0A2H1VX12   C9W8F6   O18445   A0A0K8SS51   A0A142I706   E0W9N4   I6SJ48   A0A2H1VAW7   C9W8G8   A0A2A4K1Q8   B4X989   H9JM32   A0PGD7   D7RZZ7   C9W8G7   A0A1B0RHP3   E7D005   Q86M89   B4X991   A0A2A4K1C2   A0A2A4K1R6   A0A0L7L6E9   A0A0L7LB31   J7FDV3   A0A2A4JSJ6   D7RZZ8   A0A089QAK4   A0A2A4K228   A0A2A4K0D3   A0A0X9HJY6   O18443   D7RZZ6  

Pubmed

26227816    26354079    22118469    20824821    22228503    28756777    + More
9404008    19121390    20149796    21322004    11267902    19194984   

EMBL

DQ443284    ABF51373.1    RSAL01000035    RVE51335.1    KX380993    ANS56509.1    + More
RVE51334.1    JQ904138    AFM77768.1    JQ904137    AFM77767.1    JTDY01001059    KOB74999.1    ODYU01012588    SOQ59001.1    GDQN01009850    JAT81204.1    GDQN01003329    JAT87725.1    KQ459604    KPI92468.1    GDQN01006881    JAT84173.1    KQ460813    KPJ12139.1    KR024678    ALE15220.1    GDQN01000810    JAT90244.1    NWSH01001222    PCG72058.1    PCG72057.1    GDQN01005957    JAT85097.1    KM083783    AIR09764.1    PCG72056.1    ODYU01012894    SOQ59427.1    AGBW02011133    OWR47160.1    PCG72059.1    FJ205442    ACR16006.2    FJ205439    ADM35108.1    FJ205407    ACR15975.2    FJ205425    ACR15992.2    PCG72055.1    PCG72060.1    FJ205414    ACR15982.2    KR024677    ALE15219.1    KQ459603    KPI92811.1    HM990186    ADT80834.1    KQ460883    KPJ11150.1    GDQN01004055    JAT86999.1    JN252038    AFM28251.1    KM083794    AIR09775.1    GBRD01010002    JAG55822.1    KM083792    AIR09773.1    KZ149911    PZC78104.1    FJ205444    ACR16007.1    ODYU01000971    SOQ36526.1    NWSH01000291    PCG77701.1    DQ311255    ABD36200.1    AY618890    AAV33653.1    KQ459581    KPI99177.1    JN252036    AFM28249.1    NWSH01001552    PCG70875.1    JN252045    AFM28258.1    KQ461033    KPJ09997.1    Y12273    CAA72952.1    FJ205399    ACR15968.2    ODYU01001034    SOQ36689.1    AF237417    EF531621    AAF43709.1    ABR88232.1    SOQ36525.1    KM083781    AIR09762.1    BABH01002097    Y12280    CAA72959.1    GQ354838    ACU00133.1    ODYU01007826    SOQ50918.1    KZ150191    PZC72392.1    Y12287    CAA72966.1    PCG70877.1    AY618889    AAV33652.1    AF233732    AAF71519.1    HM990173    ADT80821.1    FJ205408    ACR15976.1    PCG77700.1    ODYU01004792    SOQ45042.1    FJ205400    ACR15969.2    Y12281    CAA72960.1    GBRD01009676    JAG56148.1    KT907053    AMR44225.1    FJ205401    ADM35105.1    JQ904142    AFM77772.1    ODYU01001570    SOQ37967.1    FJ205413    ACR15981.1    PCG77693.1    EF531625    ABR88236.1    BABH01005812    AY618892    AAV33655.1    HM209420    ADI32881.1    FJ205412    ACR15980.1    KM360186    AKH49602.1    HM990175    ADT80823.1    AY251276    AAO75039.1    EF531627    ABR88238.1    PCG77694.1    PCG77703.1    JTDY01002618    KOB71083.1    JTDY01001894    KOB72615.1    JN252035    AFM28248.1    NWSH01000651    PCG75015.1    HM209421    ADI32882.1    KM083784    AIR09765.1    PCG77692.1    PCG77697.1    KP690081    ALO61083.1    SOQ36527.1    Y12279    CAA72958.1    HM209419    ADI32880.1   

Proteomes

UP000283053    UP000037510    UP000053268    UP000053240    UP000218220    UP000007151    + More
UP000005204   

PRIDE

Q1HPW8    Q2F617    H9JG67    H9JM32   

Pfam

PF00089   Trypsin

Interpro

IPR009003   Peptidase_S1_PA        + More
IPR001314   Peptidase_S1A       
IPR018114   TRYPSIN_HIS       
IPR001254   Trypsin_dom       
IPR033116   TRYPSIN_SER       
IPR036179   Ig-like_dom_sf       

SUPFAM

SSF50494   SSF50494        + More
SSF48726   SSF48726       

CDD

cd00190  Tryp_SPc

ProteinModelPortal

Q1HPW8   A0A3S2NMC5   A0A1B1LTR9   A0A3S2LDG1   I6TMX9   I6SJ44   + More
A0A0L7LI04   A0A2H1X112   A0A1E1W2N0   A0A1E1WL73   A0A194PHE1   A0A1E1WB13   A0A0N0PBU1   A0A0M4MQT7   A0A1E1WTE4   A0A2A4JK09   A0A2A4JJ19   A0A1E1WDT0   A0A089Q9M9   A0A2A4JJV5   A0A2H1X2D3   A0A212F096   A0A2A4JJQ3   C9W8J3   E0W9N7   C9W8G2   C9W8H9   A0A2A4JIX9   A0A2A4JKX6   C9W8G9   A0A0M5KXW7   A0A194PHC5   E7D016   A0A194R1N4   A0A1E1WJ19   J7FDD9   A0A089QAL5   A0A0K8SR13   A0A089QDB8   A0A2W1BWV2   C9W8J4   A0A2H1V6W6   A0A2A4K0B4   Q2F617   A0PGD5   A0A194Q0R8   J7FCZ4   A0A2A4JFK9   J7FDV8   A0A0N1PGY7   O18438   C9W8F5   A0A2H1V7A9   Q9NGY4   A0A2H1V6P6   A0A089RSY0   H9JG67   O18444   C7FF06   A0A2H1WCW9   A0A2W1BAG4   O18450   A0A2A4JFM8   A0PGD4   Q9NH07   E7D003   C9W8G3   A0A2A4K202   A0A2H1VX12   C9W8F6   O18445   A0A0K8SS51   A0A142I706   E0W9N4   I6SJ48   A0A2H1VAW7   C9W8G8   A0A2A4K1Q8   B4X989   H9JM32   A0PGD7   D7RZZ7   C9W8G7   A0A1B0RHP3   E7D005   Q86M89   B4X991   A0A2A4K1C2   A0A2A4K1R6   A0A0L7L6E9   A0A0L7LB31   J7FDV3   A0A2A4JSJ6   D7RZZ8   A0A089QAK4   A0A2A4K228   A0A2A4K0D3   A0A0X9HJY6   O18443   D7RZZ6  

PDB

2HLC     E-value=4.96268e-30,     Score=325

KEGG

732967    no KO assigned | (RefSeq) chymotrypsin-like serine protease

GO

GO:0004252   GO:0008236   GO:0016021   GO:0006508   GO:0006281   GO:0008152   GO:0016787   GO:0042626   GO:0016887   GO:0005622   GO:0006810   GO:0003824  

SignalP

Position:   1 - 17,         Likelihood:  0.986387

 

 

Length:

296

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

32.3146

Exp number, first 60 AAs:

15.4447

Total prob of N-in:

0.74651

POSSIBLE N-term signal

sequence

outside

1  -  296

 

 

Pi

226.829263

Theta

183.298504

Tajima's D

0.782398

CLR

0.014609

CSRT

0.59662016899155

Interpretation

Uncertain