Gene

KWMTBOMO11026

Pre Gene Modal

BGIBMGA008324

Annotation

PREDICTED:_hormone-sensitive_lipase_[Bombyx_mori]

Location

Bomo_Chr18(-):10148333-10171078      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 1.217 PlasmaMembrane   Reliability : 1.668

CDS

ATGGAATTTTCCGATCCGCCTGCAAGTGCTTCATACTGCTGTGCAGAAAGCAACGATGGTATTCCACCAACCTTCGCTATGTATGAAGCGCTAAAAGACTCTTGTCAGAACAACGCGACATTCTTCAAACCGGACGATACAGAAAACGGACAACGTTTATATCAAGGATTCATGACATTAAGTGACCATATAGAAACGGTGTGGCCCCTGGTGGACCATGTACGAAAAGTAGCACCACAATATGATTTTGATACAAAATCTCCCGGAAACGGATACCGAAGTTTTGTTTCAGTTGTAGACTCGTGTGTGTTATACAGTCTCAAACTAAGTCGGCAAGTCAGTACAGGACGTGAAGCACTTCTATTCCGAAAAAGCCACTTTGTGAAGGAAATAGAGTCGTGCGGCCAACTTTTAGCATCGCTCGGAACCTGTTTACATCACCTTCAGACTTTACTTGGTTGGGCACCCCCCGGAGAACTGTTTCCTACCGAACATCATACACCCGAAGAACTATTCTCTCAAGCCGACACAATAAATCAGTATTGCTTCTACGGAAGATGTCTTGGCTTTCAATTCATACCATCGATGCGCGGAATACTAAAAGGCATATCCATATGTATGGCGGGTTTCTCTGAAGCGTACTACTGTCACGGAAACGTGATTAGCTCTGTTTGGACCGGAGGGCAGTACCTGATCAACCCTGAGTTGAGGGCTAGGCGTATCGTGAATATATCGCAGTCGGCGAGTATAGAATTCTGCAAGGCGTTTTGGTTTTTAGCTGAAAGCGAAATAATGAAGCGTGTCCCCAGTTTGATGTCTTCGACGGTGGCCGTTAATAAAATCATAACGATACCACCTGAACCGTTGACGGTGACCACCCTCGAAGATAAGGAGATCACCGTCCTACCACCCACCGTACATATAGGGCTTCAGGGACTGAACATCAGACTTATTAGTGTAAACAAGAGGGTCGGTATGGCCGGCGAGAGTTCCTCATCGCTGCCGCCGTCGGATGGCGTCCTTTTCCACTGCCACGGAGGAGGCTTCGTGGCCCAAAGTTCCAAGTCGCACGAGACTTACCTCCGGGACTGGGCGGCCAAACTGAACGTGCCAATTATGTCGATCGACTACAGTCTTGCACCGCAGGCGCCCTTTCCTAGGGCTTTAGAAGAGGTCTACTACGCTTATTGTTGGCTGTTGAATAATTTTAAAACAGTCGGAACTACGGGTAAAAGAATAGTGTTCGCCGGGGATTCGGCTGGTGCCAATCTGGTCGCGGCTTGCACTGTGAAGATATTATCGACCGGCCTGCGTAAGCCTGACGGCATGTTCCTGGCGTATGCTCCTCTCAACGTGAACTTCGTGCCGAGCCCGGCGCGGCTGCTGTGCCTAATGGACCCTATACTCCCCTTCGGGTTCATGATGAGGTGTCTGAAAGCCTACGCCAGTCCAAACATGAGCGGGAACAGCAAGGACAGCAAGGACGACAAAGAGAACAACCAAAGCGTTTTGCCGAACACAACAAGCACTCCGAGCGACACAAACGGCTTCCTGAAAGTTAGCCAGTCTCAAGAAGGTATCAGCGAAGGTCCGTCGTCGTTCGAAGAGGTTTCACCGTCGGACCTCGCCGAGCTTCAGGCGCACAAGTCCGGCAGCGAACGAAGGAAGTCTTCGGACACCACGATCAGTGCGGCCTCGTTGCAGAGCGAACACACCGTCACCGGCACAACTCCTCCCGAAGACAAGTCGCAACAGTACGTCACGGATTTCTTAGAGCGTTACGTGCTGGACAGTGATACTGACTCCGAGGGGCGGAAACTGAATAGAGCAGCCAACAACGATGGCTCGCAGAGGGAGATCGAATCGGAAAACTCCAGTACACTGGTCGCCGAAAAACCGTTAACAGTCCCAACTGAAGAGGAGGGCCCCGACAACAGGATGAAGATTAAAACCAGAATAAGTGAAGCGGCCACCGGCTTCATGGGCGCGATGCAGACCAGGCTGGCCTACATCACGGGGTCCAGCGCCATCGTCAGGCCCACACAGGAAGACTTGGCGGTACGCACGAATTTGGATGCTCTGATAGCTCGCAGTCCGTCCGAAGAGTTCATATTCTCGGTGCCTCGGGACCCTTATCTGTCTCCGTACTGGGCCGATGATGAACTGCTCAAGATGTTCCCACCCGTCAGGATATTGACTGTACATTTGGACCCGTGCCTGGACGATTGCGTGATGTTCGCCAAAAAATTGAAAACACTCGGAAACGTTGTCGGCATCGAAGTGTTAGAGGGCCTGCCTCACGGATTCCTCAATTTCTCTCTCATGGTCAAGGAAGCGAACGAGGGTTCGAAACTTTGCGTCGAGAGAATGAAGCAGTTATTCGATTTGGACGCGGCGCCCGCGGCCGCCGATAACCAATTATGA

Protein

MEFSDPPASASYCCAESNDGIPPTFAMYEALKDSCQNNATFFKPDDTENGQRLYQGFMTLSDHIETVWPLVDHVRKVAPQYDFDTKSPGNGYRSFVSVVDSCVLYSLKLSRQVSTGREALLFRKSHFVKEIESCGQLLASLGTCLHHLQTLLGWAPPGELFPTEHHTPEELFSQADTINQYCFYGRCLGFQFIPSMRGILKGISICMAGFSEAYYCHGNVISSVWTGGQYLINPELRARRIVNISQSASIEFCKAFWFLAESEIMKRVPSLMSSTVAVNKIITIPPEPLTVTTLEDKEITVLPPTVHIGLQGLNIRLISVNKRVGMAGESSSSLPPSDGVLFHCHGGGFVAQSSKSHETYLRDWAAKLNVPIMSIDYSLAPQAPFPRALEEVYYAYCWLLNNFKTVGTTGKRIVFAGDSAGANLVAACTVKILSTGLRKPDGMFLAYAPLNVNFVPSPARLLCLMDPILPFGFMMRCLKAYASPNMSGNSKDSKDDKENNQSVLPNTTSTPSDTNGFLKVSQSQEGISEGPSSFEEVSPSDLAELQAHKSGSERRKSSDTTISAASLQSEHTVTGTTPPEDKSQQYVTDFLERYVLDSDTDSEGRKLNRAANNDGSQREIESENSSTLVAEKPLTVPTEEEGPDNRMKIKTRISEAATGFMGAMQTRLAYITGSSAIVRPTQEDLAVRTNLDALIARSPSEEFIFSVPRDPYLSPYWADDELLKMFPPVRILTVHLDPCLDDCVMFAKKLKTLGNVVGIEVLEGLPHGFLNFSLMVKEANEGSKLCVERMKQLFDLDAAPAAADNQL

Similarity

Belongs to the mitochondrial carrier (TC 2.A.29) family.

Uniprot

A0A2A4JU41   A0A2A4JSC6   A0A194PGG4   A0A2A4JU23   A0A0N1IB51   A0A2H1X1C4   + More
A0A067RFD0   A0A2J7RCF7   A0A182K3X0   A0A182GUE6   A0A1L8DZN9   A0A182QFL5   A0A182P067   A0A182V585   A0A2M4BDB0   W5J1P7   A0A182NRK8   A0A2M3Z688   A0A2M4BDG6   A0A182LER4   A0A2M3ZHM2   A0A1Q3F4J3   A0A1Q3F4Q3   A0A182Y6F4   A0A182MG95   A0A182VWX6   A0A2M4AKJ5   Q7QCC9   A0A182FNW2   A0A182RS77   A0A2M4BDB9   A0A1B0CEX7   A0A182UL88   A0A182HSP1   A0A182XAU4   D2A0J0   A0A1I8M5Y5   N6SXB5   T1PJV7   B0X935   A0A0M4EUI2   W8B1W7   W8B1X4   A0A2M4AL67   Q5R272   B3NK46   Q5R291   Q7JR83   A0A2M4BEA4   B4PAN7   A0A0P8YBU6   B3MGS3   A0A2M4BE73   A0A0L0CM38   A0A0K8V3P9   A0A1W4VHY2   B4MRX2   A0A034VCS4   A0A1A9W7R9   A0A0A1X7Q9   A0A1I8PMQ6   A0A1B0C082   B4GHQ4   Q28ZI3   A0A3B0IZ09   A0A3B0J2K4   B4JWG2   A0A1A9Z5H0   A0A1A9UWJ3   Q178Z9   A0A1B0FCE6   B4KS27   A0A0Q9W2K7   B4LPN9   A0A084WRJ8   A0A182IXR0   A0A034VB69   A0A232EZM5   A0A0M9AB10   A0A026VVA9   A0A1J1J1N4   A0A0C9RD05   A0A154NZW0   E9IUW1   A0A0L7QP26   A0A195C4I4   A0A2A3E4Y0   A0A088AAN0   A0A151XBF7   A0A336MRQ2   F4WCJ2   A0A3B0IYR4   A0A336MSR2   A0A195ELU1   E2C1H2   A0A1W4XKV6   A0A0P4W452   A0A1W4XVD1  

Pubmed

26354079    24845553    26483478    20920257    23761445    20966253    + More
25244985    12364791    14747013    17210077    18362917    19820115    25315136    23537049    24495485    15729003    17994087    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    18057021    26108605    25348373    25830018    15632085    17510324    24438588    28648823    24508170    30249741    21282665    21719571    20798317   

EMBL

NWSH01000670    PCG74912.1    PCG74911.1    KQ459604    KPI92481.1    PCG74910.1    + More
KQ459718    KPJ20241.1    ODYU01012629    SOQ59048.1    KK852506    KDR22472.1    NEVH01005885    PNF38505.1    JXUM01018444    JXUM01018445    JXUM01018446    KQ560513    KXJ82042.1    GFDF01002339    JAV11745.1    AXCN02000002    GGFJ01001895    MBW51036.1    ADMH02002163    ETN58147.1    GGFM01003281    MBW24032.1    GGFJ01001944    MBW51085.1    GGFM01007214    MBW27965.1    GFDL01012559    JAV22486.1    GFDL01012546    JAV22499.1    AXCM01003299    GGFK01007982    MBW41303.1    AAAB01008859    EAA08041.5    GGFJ01001905    MBW51046.1    AJWK01009430    APCN01000311    KQ971338    EFA02512.1    APGK01053114    KB741221    KB632081    ENN72419.1    ERL88581.1    KA648380    AFP63009.1    DS232517    EDS42941.1    CP012524    ALC41362.1    GAMC01019289    GAMC01019287    JAB87266.1    GAMC01019285    GAMC01019284    GAMC01019282    GAMC01019280    GAMC01019278    JAB87271.1    GGFK01008183    MBW41504.1    AB162351    CH480816    BAD72919.1    EDW48671.1    CH954179    EDV55281.1    AB162349    CM000362    CM002911    BAD72901.1    EDX07884.1    KMY95228.1    AE013599    BT003200    AAF57494.1    AAF57495.1    AAM68400.1    AAO24955.1    GGFJ01002150    MBW51291.1    CM000158    EDW91428.1    KRJ99838.1    CH902619    KPU76458.1    EDV36831.1    KPU76459.1    KPU76460.1    GGFJ01002204    MBW51345.1    JRES01000195    KNC33403.1    GDHF01033289    GDHF01024911    GDHF01018767    GDHF01009845    JAI19025.1    JAI27403.1    JAI33547.1    JAI42469.1    CH963850    EDW74861.1    GAKP01019604    JAC39348.1    GBXI01006993    GBXI01004688    JAD07299.1    JAD09604.1    JXJN01023495    CH479183    EDW36024.1    CM000071    EAL25630.2    OUUW01000001    SPP73305.1    SPP73303.1    CH916375    EDV98300.1    CH477355    EAT42820.1    CCAG010022893    CH933808    EDW10463.1    KRG05270.1    CH940648    KRF79337.1    EDW60277.1    KRF79338.1    KRF79339.1    ATLV01026105    ATLV01026106    KE525406    KFB52842.1    GAKP01019605    JAC39347.1    NNAY01001470    OXU23851.1    KQ435695    KOX80857.1    KK107796    QOIP01000013    EZA47677.1    RLU15349.1    CVRI01000065    CRL05668.1    GBYB01014474    JAG84241.1    KQ434786    KZC05122.1    GL766058    EFZ15640.1    KQ414843    KOC60329.1    KQ978292    KYM95520.1    KZ288392    PBC26342.1    KQ982327    KYQ57705.1    UFQT01002298    SSX33142.1    GL888070    EGI68172.1    SPP73304.1    SSX33140.1    KQ978739    KYN28892.1    GL451937    EFN78148.1    GDRN01093475    JAI59879.1   

Proteomes

UP000218220    UP000053268    UP000053240    UP000027135    UP000235965    UP000075881    + More
UP000069940    UP000249989    UP000075886    UP000075885    UP000075903    UP000000673    UP000075884    UP000075882    UP000076408    UP000075883    UP000075920    UP000007062    UP000069272    UP000075900    UP000092461    UP000075902    UP000075840    UP000076407    UP000007266    UP000095301    UP000019118    UP000030742    UP000002320    UP000092553    UP000001292    UP000008711    UP000000304    UP000000803    UP000002282    UP000007801    UP000037069    UP000192221    UP000007798    UP000091820    UP000095300    UP000092460    UP000008744    UP000001819    UP000268350    UP000001070    UP000092445    UP000078200    UP000008820    UP000092444    UP000009192    UP000008792    UP000030765    UP000075880    UP000215335    UP000053105    UP000053097    UP000279307    UP000183832    UP000076502    UP000053825    UP000078542    UP000242457    UP000005203    UP000075809    UP000007755    UP000078492    UP000008237    UP000192223   

PRIDE

Q7JR83   

Pfam

PF07859   Abhydrolase_3        + More
PF06350   HSL_N
PF00010   HLH
PF07539   DRIM
PF00153   Mito_carr

Interpro

IPR010468   HSL_N        + More
IPR033140   Lipase_GDXG_put_SER_AS       
IPR029058   AB_hydrolase       
IPR013094   AB_hydrolase_3       
IPR011598   bHLH_dom       
IPR036638   HLH_DNA-bd_sf       
IPR011430   DRIM       
IPR016024   ARM-type_fold       
IPR002168   Lipase_GDXG_HIS_AS       
IPR018108   Mitochondrial_sb/sol_carrier       
IPR023395   Mt_carrier_dom_sf       

SUPFAM

SSF53474   SSF53474        + More
SSF47459   SSF47459       
SSF48371   SSF48371       
SSF103506   SSF103506       

Gene 3D

3.40.50.1820     4.10.280.10     1.50.40.10    

CDD

cd00083  HLH

ProteinModelPortal

A0A2A4JU41   A0A2A4JSC6   A0A194PGG4   A0A2A4JU23   A0A0N1IB51   A0A2H1X1C4   + More
A0A067RFD0   A0A2J7RCF7   A0A182K3X0   A0A182GUE6   A0A1L8DZN9   A0A182QFL5   A0A182P067   A0A182V585   A0A2M4BDB0   W5J1P7   A0A182NRK8   A0A2M3Z688   A0A2M4BDG6   A0A182LER4   A0A2M3ZHM2   A0A1Q3F4J3   A0A1Q3F4Q3   A0A182Y6F4   A0A182MG95   A0A182VWX6   A0A2M4AKJ5   Q7QCC9   A0A182FNW2   A0A182RS77   A0A2M4BDB9   A0A1B0CEX7   A0A182UL88   A0A182HSP1   A0A182XAU4   D2A0J0   A0A1I8M5Y5   N6SXB5   T1PJV7   B0X935   A0A0M4EUI2   W8B1W7   W8B1X4   A0A2M4AL67   Q5R272   B3NK46   Q5R291   Q7JR83   A0A2M4BEA4   B4PAN7   A0A0P8YBU6   B3MGS3   A0A2M4BE73   A0A0L0CM38   A0A0K8V3P9   A0A1W4VHY2   B4MRX2   A0A034VCS4   A0A1A9W7R9   A0A0A1X7Q9   A0A1I8PMQ6   A0A1B0C082   B4GHQ4   Q28ZI3   A0A3B0IZ09   A0A3B0J2K4   B4JWG2   A0A1A9Z5H0   A0A1A9UWJ3   Q178Z9   A0A1B0FCE6   B4KS27   A0A0Q9W2K7   B4LPN9   A0A084WRJ8   A0A182IXR0   A0A034VB69   A0A232EZM5   A0A0M9AB10   A0A026VVA9   A0A1J1J1N4   A0A0C9RD05   A0A154NZW0   E9IUW1   A0A0L7QP26   A0A195C4I4   A0A2A3E4Y0   A0A088AAN0   A0A151XBF7   A0A336MRQ2   F4WCJ2   A0A3B0IYR4   A0A336MSR2   A0A195ELU1   E2C1H2   A0A1W4XKV6   A0A0P4W452   A0A1W4XVD1  

PDB

4WY5     E-value=3.12689e-15,     Score=202

KEGG

101737209    K07188 hormone-sensitive lipase [EC:3.1.1.79] | (RefSeq) hormone-sensitive lipase

GO

GO:0008203   GO:0016042   GO:0016298   GO:0046983   GO:0016021   GO:0005829   GO:0006642   GO:0005811   GO:0008152   GO:0016787   GO:0042626   GO:0016887   GO:0005622   GO:0006810   GO:0003824  

Length:

807

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.06464

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00035

outside

1  -  807

 

 

Pi

26.4047

Theta

194.499166

Tajima's D

0.902253

CLR

0.215305

CSRT

0.63586820658967

Interpretation

Uncertain