Gene

KWMTBOMO11015

Annotation

PREDICTED:_fasciclin-2-like_isoform_X3_[Bombyx_mori]

Location

Bomo_Chr18(-):9793646-9925798      View in EpiBrowser

Full name

Fasciclin-2      

Alternative Name

Fasciclin II

Location in the cell

Cytoplasmic   Reliability : 1.266

CDS

ATGGAAGCTGCTGCTGGAACTCGTCCGGAAATATACACAGAAGCAATGCCTGCCAAACAGCTTCAATTGTTGTATATATCCTCGATAACGCCTGCAATGGCTGGAAACTATTCCTGTGAGGCTACTTACACGAATATCCCTCTTAGCGCCAGCGTTATTTTGGATACATTTGTTGCTATCACTTGGACAAATGCTAATGAGAACCAGTATGCAACCAAAGGCAAAGATTTTAAAGTCATGTGCGAGGTTACAGCCGAGCCTGCACCATCAGTAGATTGGTTTAAAGAAGAAAATCCCATCGTAACTGGTGACAGATACGTAATTCACGCTAATGGTCTAATGATTAAAAACGTTCAAGAAAGTGATGATGGTACATATACTTGTAGAGCTGTCGTAATGCAAACTGGTGAACTTGCGGAAAGGAACATTAAACTTGAGGTTTACACCGCACCAGAAATGGAAGAACGAGAGACGACAGTTAGAATCAAAGAGGGAGAATCAGCTGCAATCACTTGCAAAGCGAGAGGAAAGCCGCCACCAACATATACTTGGATTAAAGCTTCGACACGCGAGAACCTGGCTACTACATCACGATTCAACGTTAACGAAAACACTGGACTCTTAACTTTTGATAGAGTCGAAGCCGCTGATTACGGAAAGTATATTTGCAGTGCGGTTAATAAGGCTGGTCAAAACGAAACCGAAATAGAAGTCGAAGTACTTGTGAAGCCAAGGATTTTCGAACTCTACAATACTACTGCTCCCGAAAAACAAGAAGGCAGACTGGAGTGTAAAGCTACTGGTCGTCCAGCACCTCGCATTAGTTTCCGTAAGCGGAGCAATAGTGAGCGTTTTGTTAATGGACCAAATGATGGTGGAAGGATCACTATTGAGACCAGCAGTCATCAATCAGGAGATCAAATTGAATCTAGCGCAGTAATCATGATTTCGAATTTGAATAGAACTGATGATGGTTTATACGAGTGCATTGCTGAGAACGATGCTGGTGAAGCTTGGCGAAACGGCCATTTGGCTGTGCAGTTCCGGCCAACCTTTGAAAGGATGCCTACAGTACCGATATGGAGTTGGAATGGGCAAACTGTAAATTTGACGTGCGTCGCTGAGAGTATTCCCAATGCTACGATCAAGTGGAGGTTCCGTGACGCTGATCTGGTAGAAACGCCCCATATCAAAATCTTTGGGTCTGGCCCAATAAGCTATGTCACAATCACGCCACTGGATCGTGGACTGTATGGAATATACAAGTGTGTTGCTACCAATACTCTAGGAGAAGCAGAGCATGTCATTCAGTTCAGAGAAGCTTTTCCTCCCGGACCTGTAGTACAGGCAAGACAAGAAACTATCACAGCAACCTCAGTTACGTTCAATATTGTTGGACCTGCTGAAGATATGGGTCCGCCGATCTTGGCTTATGTTGCCCAATTCAAAGAAAATGCAAACTTCGACTGGAACTTAGCACAGAACCGCACGTGGTCGGTTAATTCCCCATACACTGTGGAAAACTTGAGACCAATGTTTACCTATGACTTTAGATTCGCTGCAGTTAATCAAGTTGGCATTGGTAGTTGGGGATCTCCTATTACGGTTATCATGCCAAGAAGGTCACCACCAGAACAGCCGAAATGGAGAGAGAACCTTAGCTCGGAATCGCTTATTCACGGAAAATACGCAGACAGATATGAACTGAAGTGGAAAATACCCGCTCATAATGGGGAGCCTATTGACATGTACGAAATCCGCTATTGTCCGGTTTTGAAGATAAGCGGCGAATGGCGTGTGTCGTCGGAAAACGAGTGCGTTACCCAAGAACTTAAGTCATTCGAAGCCATTACATACGAAGTCAGAGGGCTACATCCGGACACTCGTTACCGCATTCATCTGCGGGCTCATAACCAGCTCGGTTTCTCACTGCCCGCCCAACTGTACGTCCAAACTGCTCTTGGTGTTGAACGCTCTGGTTTTGCTCACGCGCAACTTCTATCGAGCGGGGCAATTATAGGGCTGTCTTTGGCTGGCGTCATCATTTGCCTTCTCATCGTGGATCTCTTACTGCTGTGCTTCAGAAAACAGGGAGTGATTGCTACCCTGTGCGGCAAACGCGCGAAGAAACACAACGACGAAGAAGCAAAATTGGGAAGGGATGAGAAGGAACCGTTGAAAGACACAGATGATGCAATGAAGCGAAACTCCTCAGTGGAATTCGATGGACATCGGGTCTACGCGACAAGCGGGGGCCCCATCATTGGCAAGAACTCTGCAGTTTAA

Protein

MEAAAGTRPEIYTEAMPAKQLQLLYISSITPAMAGNYSCEATYTNIPLSASVILDTFVAITWTNANENQYATKGKDFKVMCEVTAEPAPSVDWFKEENPIVTGDRYVIHANGLMIKNVQESDDGTYTCRAVVMQTGELAERNIKLEVYTAPEMEERETTVRIKEGESAAITCKARGKPPPTYTWIKASTRENLATTSRFNVNENTGLLTFDRVEAADYGKYICSAVNKAGQNETEIEVEVLVKPRIFELYNTTAPEKQEGRLECKATGRPAPRISFRKRSNSERFVNGPNDGGRITIETSSHQSGDQIESSAVIMISNLNRTDDGLYECIAENDAGEAWRNGHLAVQFRPTFERMPTVPIWSWNGQTVNLTCVAESIPNATIKWRFRDADLVETPHIKIFGSGPISYVTITPLDRGLYGIYKCVATNTLGEAEHVIQFREAFPPGPVVQARQETITATSVTFNIVGPAEDMGPPILAYVAQFKENANFDWNLAQNRTWSVNSPYTVENLRPMFTYDFRFAAVNQVGIGSWGSPITVIMPRRSPPEQPKWRENLSSESLIHGKYADRYELKWKIPAHNGEPIDMYEIRYCPVLKISGEWRVSSENECVTQELKSFEAITYEVRGLHPDTRYRIHLRAHNQLGFSLPAQLYVQTALGVERSGFAHAQLLSSGAIIGLSLAGVIICLLIVDLLLLCFRKQGVIATLCGKRAKKHNDEEAKLGRDEKEPLKDTDDAMKRNSSVEFDGHRVYATSGGPIIGKNSAV

Description

Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles.

Keywords

Alternative splicing   Cell adhesion   Cell membrane   Complete proteome   Developmental protein   Differentiation   Disulfide bond   Glycoprotein   GPI-anchor   Immunoglobulin domain   Lipoprotein   Membrane   Neurogenesis   Phosphoprotein   Reference proteome   Repeat   Signal   Transmembrane   Transmembrane helix  

Feature

chain  Fasciclin-2
splice variant  In isoform 3.

Uniprot

A0A2H1VTW8   O97137   A0A212EWX3   A0A2S0U496   A0A1E1W4M9   A0A0N1PJJ7   + More
A0A194PHG1   A0A3S2NUX5   O97136   M9PGF6   M9PJ19   A0A0K8VM92   A0A0Q5TGV4   A0A0Q5T3C4   A0A0R1E9P7   A0A0R3P6T5   A0A0R3P794   A0A0R1E9F0   A0A3B0KR84   B4NPA5   A0A0P8XKB6   A0A0P8XKI0   A0A1W4V1H1   P34082   A0A0K8VU68   B4I117   A0A0Q5T2P2   B3NSV0   A0A1I8PNP8   A0A1I8PNI2   X2JAF4   A0A1I8NA37   A0A3B0KKP3   A0A0R1E9P9   A0A1I8NA28   A0A0R3P267   B4Q080   A0A1I8NA30   Q29FP8   A0A336MEN5   A0A336MUJ8   A0A1B6F0N4   A0A0Q9W7E4   A0A0Q9XSX8   A0A0Q9XN84   B3MSK8   A0A0N8NZU1   A0A1W4UP20   A0A1B6HIY2   A0A1W4V303   A0A1I8PNP6   A0A1I8PNK8   A0A1I8NA33   A0A1I8NA31   A0A1I8NA35   X2JCI0   B4JMR5   B4M7M9   B4L6N6   A0A0Q9XHL8   A0A2P8ZEM8   A0A0M5JA94   A0A1S4FLI6   Q16WM8   C0PTW6   A0A1L8DM60   A0A154PIM1   P34082-2   D2A0I5   P34082-3   A0A1W4V1U3   A0A067R8W3   A0A0K8WD47   A0A1W4X5A8   A0A0K8U222   A0A0Q5TGA1   A0A0Q5T2Y3   A0A3B0K902   A0A1B6FE97   A0A3B0K773   A0A0A1WM21   B4R4F4   W8APR8   W8B022   A0A0A1XH77   A0A3B0KUZ0   A0A310SH41   A0A0R3P271   A0A0R1EFX4   A0A2M4AFG3   A0A2M4AGE8   Q7QCU0   A0A0R1EB60   A0A2M4AGH4   A0A2M4AFC8   A0A2M4AGF3   A0A139WJS3   B0WB75   C0MQW2   A0A1W4UPK6  

Pubmed

10375511    22118469    26354079    10731132    12537568    12537572    + More
12537573    12537574    16110336    17569856    17569867    17994087    17550304    15632085    1913818    10731137    17893096    18327897    25315136    18057021    29403074    17510324    18362917    19820115    24845553    25830018    24495485    12364791    14747013    17210077   

EMBL

ODYU01004420    SOQ44273.1    AF103900    AAD17919.1    AGBW02011903    OWR45947.1    + More
MG674091    AWB36300.1    GDQN01009119    JAT81935.1    KQ459718    KPJ20235.1    KQ459604    KPI92488.1    RSAL01000170    RVE45195.1    AF103899    AAD17918.1    AE014298    AGB95083.1    AGB95081.1    GDHF01012644    JAI39670.1    CH954180    KQS29707.1    KQS29711.1    CM000162    KRK06013.1    CH379065    KRT07301.1    KRT07299.1    KRK06012.1    OUUW01000018    SPP89149.1    CH964291    EDW86345.2    CH902622    KPU75269.1    KPU75267.1    M77165    M77166    AL033125    BT014661    GDHF01009911    JAI42403.1    CH480819    EDW53198.1    KQS29708.1    EDV45780.1    AHN59325.1    SPP89150.1    KRK06011.1    KRT07300.1    EDX01232.1    EAL31531.2    UFQT01000889    SSX27851.1    UFQT01002306    SSX33181.1    GECZ01026346    GECZ01006330    JAS43423.1    JAS63439.1    CH940653    KRF80792.1    CH933812    KRG07128.1    KRG07130.1    EDV34763.1    KPU75268.1    GECU01033033    JAS74673.1    AHN59326.1    CH916371    EDV92008.1    EDW62796.2    KRF80794.1    EDW06032.2    KRG07129.1    PYGN01000078    PSN54959.1    CP012528    ALC48224.1    CH477561    EAT38982.1    BT071811    ACN58574.1    GFDF01006619    JAV07465.1    KQ434908    KZC11324.1    KQ971338    EFA01679.2    KK852624    KDR19938.1    GDHF01003574    JAI48740.1    GDHF01031743    JAI20571.1    KQS29710.1    KQS29709.1    SPP89152.1    GECZ01021248    JAS48521.1    SPP89153.1    GBXI01014849    JAC99442.1    CM000366    EDX17044.1    GAMC01020063    GAMC01020062    GAMC01020060    JAB86493.1    GAMC01020059    JAB86496.1    GBXI01003543    JAD10749.1    SPP89151.1    KQ769211    OAD52890.1    KRT07298.1    KRK06010.1    GGFK01006182    MBW39503.1    GGFK01006534    MBW39855.1    AAAB01008859    EAA07748.3    KRK06014.1    GGFK01006562    MBW39883.1    GGFK01006163    MBW39484.1    GGFK01006535    MBW39856.1    KYB28045.1    DS231877    EDS42140.1    FN295954    CAX64461.1   

Proteomes

UP000007151    UP000053240    UP000053268    UP000283053    UP000000803    UP000008711    + More
UP000002282    UP000001819    UP000268350    UP000007798    UP000007801    UP000192221    UP000001292    UP000095300    UP000095301    UP000008792    UP000009192    UP000001070    UP000245037    UP000092553    UP000008820    UP000076502    UP000007266    UP000027135    UP000192223    UP000000304    UP000007062    UP000002320   

PRIDE

P34082    C0PTW6   

Pfam

PF00041   fn3        + More
PF07679   I-set
PF00047   ig
PF08205   C2-set_2

Interpro

IPR013783   Ig-like_fold        + More
IPR003961   FN3_dom       
IPR003599   Ig_sub       
IPR007110   Ig-like_dom       
IPR036116   FN3_sf       
IPR013098   Ig_I-set       
IPR009138   Neural_cell_adh       
IPR036179   Ig-like_dom_sf       
IPR003598   Ig_sub2       
IPR013151   Immunoglobulin       
IPR013162   CD80_C2-set       

SUPFAM

SSF49265   SSF49265        + More
SSF48726   SSF48726       

Gene 3D

2.60.40.10    

CDD

cd00063  FN3

ProteinModelPortal

A0A2H1VTW8   O97137   A0A212EWX3   A0A2S0U496   A0A1E1W4M9   A0A0N1PJJ7   + More
A0A194PHG1   A0A3S2NUX5   O97136   M9PGF6   M9PJ19   A0A0K8VM92   A0A0Q5TGV4   A0A0Q5T3C4   A0A0R1E9P7   A0A0R3P6T5   A0A0R3P794   A0A0R1E9F0   A0A3B0KR84   B4NPA5   A0A0P8XKB6   A0A0P8XKI0   A0A1W4V1H1   P34082   A0A0K8VU68   B4I117   A0A0Q5T2P2   B3NSV0   A0A1I8PNP8   A0A1I8PNI2   X2JAF4   A0A1I8NA37   A0A3B0KKP3   A0A0R1E9P9   A0A1I8NA28   A0A0R3P267   B4Q080   A0A1I8NA30   Q29FP8   A0A336MEN5   A0A336MUJ8   A0A1B6F0N4   A0A0Q9W7E4   A0A0Q9XSX8   A0A0Q9XN84   B3MSK8   A0A0N8NZU1   A0A1W4UP20   A0A1B6HIY2   A0A1W4V303   A0A1I8PNP6   A0A1I8PNK8   A0A1I8NA33   A0A1I8NA31   A0A1I8NA35   X2JCI0   B4JMR5   B4M7M9   B4L6N6   A0A0Q9XHL8   A0A2P8ZEM8   A0A0M5JA94   A0A1S4FLI6   Q16WM8   C0PTW6   A0A1L8DM60   A0A154PIM1   P34082-2   D2A0I5   P34082-3   A0A1W4V1U3   A0A067R8W3   A0A0K8WD47   A0A1W4X5A8   A0A0K8U222   A0A0Q5TGA1   A0A0Q5T2Y3   A0A3B0K902   A0A1B6FE97   A0A3B0K773   A0A0A1WM21   B4R4F4   W8APR8   W8B022   A0A0A1XH77   A0A3B0KUZ0   A0A310SH41   A0A0R3P271   A0A0R1EFX4   A0A2M4AFG3   A0A2M4AGE8   Q7QCU0   A0A0R1EB60   A0A2M4AGH4   A0A2M4AFC8   A0A2M4AGF3   A0A139WJS3   B0WB75   C0MQW2   A0A1W4UPK6  

PDB

2JLL     E-value=4.84007e-26,     Score=295

KEGG

101743686    K06491 neural cell adhesion molecule | (RefSeq) fasciclin-2-like

GO

GO:0007155   GO:0016021   GO:0016020   GO:0050803   GO:0007612   GO:0050808   GO:0007614   GO:0048149   GO:0007528   GO:0061174   GO:0008045   GO:0016319   GO:0005829   GO:0072499   GO:0005737   GO:0072553   GO:0048667   GO:0036062   GO:0042059   GO:0031225   GO:0042995   GO:0008582   GO:0031594   GO:0007413   GO:0097482   GO:1904800   GO:0035158   GO:0001746   GO:0035159   GO:0008038   GO:0005886   GO:0048167   GO:0007156   GO:0008355   GO:0042734   GO:0048786   GO:0045211   GO:0043005   GO:0030424   GO:0007611   GO:0048803   GO:0030017   GO:0005515   GO:0006810   GO:0042626   GO:0016887   GO:0005622   GO:0003824  

Subcellular location

Cell membrane  

Length:

761

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

23.24538

Exp number, first 60 AAs:

0.27271

Total prob of N-in:

0.01384

outside

1  -  671

TMhelix

672  -  694

inside

695  -  761

 

 

Pi

240.048229

Theta

184.504007

Tajima's D

1.087613

CLR

0.232865

CSRT

0.685815709214539

Interpretation

Uncertain