Gene

KWMTBOMO11014

Annotation

PREDICTED:_fasciclin-2-like_[Papilio_machaon]

Location

Bomo_Chr18(-):9710796-9740648      View in EpiBrowser

Full name

Fasciclin-2      

Alternative Name

Fasciclin II

Location in the cell

Cytoplasmic   Reliability : 2.094 PlasmaMembrane   Reliability : 1.514

CDS

ATGCAATACATAAAATGGACAGATATAAACAATGAAATCATCACTGCAGGACCAGGTACAGATTCGTTGATTTACGTCGAAAAACAAAGCGACGGTCTAAATATTCACATTCCAAAGGTCAGCAAATCAATGTCTGGAGCTTACAAGTGCATAACAAATTTCGAAGGGCAACAGTATGTCCAGACTCATACAATAGAAGCATATGATCCATTGTACTTTATTAATGCTGCAGAAGTTCAGCATATTATGGAATCGCAAGATTCACGAATCAATTGTGAAGCACGCGGTGAATACCCTCCATTAATTACATGGCACAAAGGAGAAGAGAACGCATTAGTTGAAATTCAAAATAGTGAAAAATATTCAATCACAAAGGAAGGGTTGATAGTAAGGAACGTAACTACTGAAGATGGTGGAACGTATAAATGTACAGCAATGGTTATGGTCACAGGGGAAGAAGTTGATAGATTTATAAAAGTTGAGGTTATGACCGTACCAATAATTCAGGACATTATTGGTATCCCTAATACAATAGTCATGTTAGGTTCAAAGCTTTCAGTTGAATGTATAGCGGAGGCTAAACCACAACCTGAATATATTTGGAATAAAGTGTACACGGGTCCGAACGATGAAGGGAATCAAACATGGAAGCAAGTAGCTAATACATTAATATTTGATGATATAAAGGGTTATGATGCTGGTTACTACGAATGCACTGCGTACAATATGGCCGGTAATTCTACTAGTGGTGCACTAATCGAGGTACTAGTTCCACCAGAAATATTTGGTTTTGATAACATGACTGCCGAGGAAGGGACCAATATCAAAATCGCCTGTGAAGCTCTGGGAATTCCGAAACCCAACATCACAGTTACAACGAGTATATTTGATTCCGACGAAAATGGAGAAAAAAATACTGAACTACCGTTAGATTGGTCATTTGTTGTTGAGCGATATCATAAAGGAGTTTACTATTGTAATGCGATTAATGAAGTTGGTAATGCATCGAAGACAATGTACTTGACAGTTTTACATAAACCGTACTTTGAGTATCCTACCGAAGATCTCTGGGGTTGGAACGGTAAAGTTTTCAATTTGAGTTGCTCCCACGAAAGCGAACCTCCTTCTGTTATATCTTGGAGATTTCAAGGTAACGAGATACCGACAGCAGAACAAGTCGAGTTAAACAAACAGCTAATAGAGAAACTAAACAATGCTCAGGAACAATACCTTCCTGTAAATATTGACGAAAACTTTTTATACGGAGTTTACGAATGTGTTGCTAAAAACGCTTACGGTGAAGCAACGAAGACGATCACTTTGAAGAAAGGCTTTGTACCTTCCGTCGTAAACAACATTACAATCGAACAACAAGCGGCAACATCAGTAACCTTTTCCATACAAGAGCCAAGTGATTACGAAGGTCCCGAGGTAATCGGGTACACCGCGGAATACGACCAGGCGGCCAACTATGAAATAACTCACATACATCTAAACAGAACTTGGGCTATAAATAGACCGTTCAAATTAGAAAAACTGAAGCCGAATACAACGCATCACGTGAAATTCGCTGCTATAAATGAAGCGGGCACCGGACCTTGGAGTGAAACACTAGTTTTTGAAACCCTTGAAAGATCAGTACCAGAGCCTCCGGTCCTAGACTCGGATTACGTGCAAATTGAGAGCCCGGACAACGTACTGAAATGGAAAGCGCCCGCAGACAATGGAGATTCAATCGACTATTACGCCGTACGATATTGTCCGGTGGACGATGATTCAGACGGTGAGCTGTGCGGAGAAGAACGTATTGGAGAAAACACTGAATTCAATTTGAGTAGTTTGGAACACAACACGACTTACTTCGTTGAGATCATAGCGCATAATGCACAAGGAAACTCCACGCCCTCAAATATCACACTAATAACTGCAGCGCTATCGACACACAATACTTTGGGCTTATTGTCGGCCGGAGCTATAATAGGCATAGCTGTAGTTGTAGTTGTCATATGTTTAGTTTTACTAGACTTAGTGCTTTGTGCTTGGAGGAAGCAGGGTATCATTGCGACATGTTGCTCGAAGAAAACCAAAGACGACGAGTTGAAGTCACGCGATGAAAAAGGTCTTTTGAGAGACAACGGTGATTTAGAGGACTGTCACAAGAGGCCAGACAAAGGTCACAAGGAATACGAGTACAATAAGACCACGGGGATTATCACCGGGAAGCATTCCGCTGTTTAA

Protein

MQYIKWTDINNEIITAGPGTDSLIYVEKQSDGLNIHIPKVSKSMSGAYKCITNFEGQQYVQTHTIEAYDPLYFINAAEVQHIMESQDSRINCEARGEYPPLITWHKGEENALVEIQNSEKYSITKEGLIVRNVTTEDGGTYKCTAMVMVTGEEVDRFIKVEVMTVPIIQDIIGIPNTIVMLGSKLSVECIAEAKPQPEYIWNKVYTGPNDEGNQTWKQVANTLIFDDIKGYDAGYYECTAYNMAGNSTSGALIEVLVPPEIFGFDNMTAEEGTNIKIACEALGIPKPNITVTTSIFDSDENGEKNTELPLDWSFVVERYHKGVYYCNAINEVGNASKTMYLTVLHKPYFEYPTEDLWGWNGKVFNLSCSHESEPPSVISWRFQGNEIPTAEQVELNKQLIEKLNNAQEQYLPVNIDENFLYGVYECVAKNAYGEATKTITLKKGFVPSVVNNITIEQQAATSVTFSIQEPSDYEGPEVIGYTAEYDQAANYEITHIHLNRTWAINRPFKLEKLKPNTTHHVKFAAINEAGTGPWSETLVFETLERSVPEPPVLDSDYVQIESPDNVLKWKAPADNGDSIDYYAVRYCPVDDDSDGELCGEERIGENTEFNLSSLEHNTTYFVEIIAHNAQGNSTPSNITLITAALSTHNTLGLLSAGAIIGIAVVVVVICLVLLDLVLCAWRKQGIIATCCSKKTKDDELKSRDEKGLLRDNGDLEDCHKRPDKGHKEYEYNKTTGIITGKHSAV

Description

Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles.

Keywords

Cell adhesion   Developmental protein   Differentiation   Direct protein sequencing   Disulfide bond   Glycoprotein   Immunoglobulin domain   Membrane   Neurogenesis   Repeat   Signal   Transmembrane   Transmembrane helix   Alternative splicing   Cell membrane   Complete proteome   GPI-anchor   Lipoprotein   Phosphoprotein   Reference proteome  

Feature

chain  Fasciclin-2
splice variant  In isoform 3.

Uniprot

A0A0N1ICX9   A0A194PID6   A0A2H1W406   A0A2A4J6K3   A0A212EWS7   A0A3S2NE90   + More
A0A1E1W4M9   A0A0N1PJJ7   A0A194PHG1   A0A3S2NUX5   A0A2H1VTW8   A0A212EWX3   O97137   A0A2S0U496   O97136   A0A1B6FE97   W8APR8   A0A1B6F0N4   T1PK59   A0A1I8NA28   A0A1I8PNP8   A0A1I8NA31   A0A1I8PNP6   W8B022   A0A0K8U222   A0A0K8VM92   P22648   A0A0K8WD47   A0A0K8VU68   Q16WM8   T1PLG3   A0A1I8NA32   A0A1S4FLI6   A0A1I8PNN5   A0A1I8NA30   A0A2P8ZEM8   A0A1B0G304   A0A1I8NA35   A0A1I8NA37   A0A1I8PNI2   A0A1I8NA33   A0A1B6HIY2   A0A1I8PNK8   A0A1Y1KAP1   A0A1Y1KD33   D2A0I5   A0A1Y1KDQ0   A0A0A1XH77   A0A139WJS3   C0MQW2   A0A0A1WM21   A0A2R7WJA1   A0A0Q9W7E1   B4NPA5   A0A0Q9W7E4   B4M7M9   A0A0L0BT60   C0PTW6   A0A182U3S5   A0A182XHS0   B4JMR5   A0A182HTL7   A0A3B0KUZ0   P34082-3   W8B9N4   A0A3B0K773   M9PJ19   X2JCI0   P34082-2   Q7QCU0   A0A3B0KKP3   A0A182PQN0   P34082   A0A2M4BE53   A0A3B0KR84   A0A0Q5TGA1   A0A2S2P3X5   A0A182V0J4   A0A0Q9XSX8   X2JAF4   E0VLC3   A0A182QS06   A0A2H8TP34   M9PGF6   A0A3B0K902   B0WB75   A0A0Q5TGV4   A0A1A9X4L6   A0A182KB15   A0A0R3P271   A0A0Q5T2Y3   A0A0R3P6T5   B4L6N6   A0A0R1EB60   A0A0M5JA94   Q29FP8   A0A182R4P0   B3NSV0   X1WIF0   A0A0R1EFX4  

Pubmed

26354079    22118469    10375511    24495485    25315136    3187519    + More
2839842    17510324    29403074    28004739    18362917    19820115    25830018    17994087    18057021    26108605    1913818    10731132    12537572    10731137    17893096    18327897    12537568    12537573    12537574    16110336    17569856    17569867    12364791    14747013    17210077    20566863    15632085    17550304   

EMBL

KQ459718    KPJ20234.1    KQ459604    KPI92489.1    ODYU01006186    SOQ47821.1    + More
NWSH01002913    PCG67308.1    AGBW02011903    OWR45946.1    RSAL01000170    RVE45193.1    GDQN01009119    JAT81935.1    KPJ20235.1    KPI92488.1    RVE45195.1    ODYU01004420    SOQ44273.1    OWR45947.1    AF103900    AAD17919.1    MG674091    AWB36300.1    AF103899    AAD17918.1    GECZ01021248    JAS48521.1    GAMC01020063    GAMC01020062    GAMC01020060    JAB86493.1    GECZ01026346    GECZ01006330    JAS43423.1    JAS63439.1    KA649069    AFP63698.1    GAMC01020059    JAB86496.1    GDHF01031743    JAI20571.1    GDHF01012644    JAI39670.1    J03789    GDHF01003574    JAI48740.1    GDHF01009911    JAI42403.1    CH477561    EAT38982.1    KA649544    AFP64173.1    PYGN01000078    PSN54959.1    CCAG010006558    CCAG010006559    GECU01033033    JAS74673.1    GEZM01089357    JAV57528.1    GEZM01089360    JAV57525.1    KQ971338    EFA01679.2    GEZM01089359    JAV57526.1    GBXI01003543    JAD10749.1    KYB28045.1    FN295954    CAX64461.1    GBXI01014849    JAC99442.1    KK854896    PTY19579.1    CH940653    KRF80793.1    CH964291    EDW86345.2    KRF80792.1    EDW62796.2    KRF80794.1    JRES01001388    KNC23211.1    BT071811    ACN58574.1    CH916371    EDV92008.1    APCN01000568    OUUW01000018    SPP89151.1    M77165    M77166    AL033125    AE014298    BT014661    GAMC01020061    JAB86494.1    SPP89153.1    AGB95081.1    AHN59326.1    AAAB01008859    EAA07748.3    SPP89150.1    GGFJ01002184    MBW51325.1    SPP89149.1    CH954180    KQS29710.1    GGMR01010977    MBY23596.1    CH933812    KRG07128.1    AHN59325.1    DS235271    EEB14179.1    AXCN02000328    GFXV01004159    MBW15964.1    AGB95083.1    SPP89152.1    DS231877    EDS42140.1    KQS29707.1    CH379065    KRT07298.1    KQS29709.1    KRT07301.1    EDW06032.2    CM000162    KRK06014.1    CP012528    ALC48224.1    EAL31531.2    EDV45780.1    ABLF02030091    ABLF02030092    ABLF02030093    KRK06010.1   

Proteomes

UP000053240    UP000053268    UP000218220    UP000007151    UP000283053    UP000095301    + More
UP000095300    UP000008820    UP000245037    UP000092444    UP000007266    UP000008792    UP000007798    UP000037069    UP000075902    UP000076407    UP000001070    UP000075840    UP000268350    UP000000803    UP000007062    UP000075885    UP000008711    UP000075903    UP000009192    UP000009046    UP000075886    UP000002320    UP000091820    UP000075881    UP000001819    UP000002282    UP000092553    UP000075900    UP000007819   

PRIDE

P22648    C0PTW6    P34082   

Pfam

PF00041   fn3        + More
PF07679   I-set
PF00047   ig

Interpro

IPR009138   Neural_cell_adh        + More
IPR013098   Ig_I-set       
IPR003599   Ig_sub       
IPR013783   Ig-like_fold       
IPR036116   FN3_sf       
IPR003961   FN3_dom       
IPR007110   Ig-like_dom       
IPR003598   Ig_sub2       
IPR036179   Ig-like_dom_sf       
IPR013151   Immunoglobulin       

SUPFAM

SSF49265   SSF49265        + More
SSF48726   SSF48726       

Gene 3D

2.60.40.10    

CDD

cd00063  FN3

ProteinModelPortal

A0A0N1ICX9   A0A194PID6   A0A2H1W406   A0A2A4J6K3   A0A212EWS7   A0A3S2NE90   + More
A0A1E1W4M9   A0A0N1PJJ7   A0A194PHG1   A0A3S2NUX5   A0A2H1VTW8   A0A212EWX3   O97137   A0A2S0U496   O97136   A0A1B6FE97   W8APR8   A0A1B6F0N4   T1PK59   A0A1I8NA28   A0A1I8PNP8   A0A1I8NA31   A0A1I8PNP6   W8B022   A0A0K8U222   A0A0K8VM92   P22648   A0A0K8WD47   A0A0K8VU68   Q16WM8   T1PLG3   A0A1I8NA32   A0A1S4FLI6   A0A1I8PNN5   A0A1I8NA30   A0A2P8ZEM8   A0A1B0G304   A0A1I8NA35   A0A1I8NA37   A0A1I8PNI2   A0A1I8NA33   A0A1B6HIY2   A0A1I8PNK8   A0A1Y1KAP1   A0A1Y1KD33   D2A0I5   A0A1Y1KDQ0   A0A0A1XH77   A0A139WJS3   C0MQW2   A0A0A1WM21   A0A2R7WJA1   A0A0Q9W7E1   B4NPA5   A0A0Q9W7E4   B4M7M9   A0A0L0BT60   C0PTW6   A0A182U3S5   A0A182XHS0   B4JMR5   A0A182HTL7   A0A3B0KUZ0   P34082-3   W8B9N4   A0A3B0K773   M9PJ19   X2JCI0   P34082-2   Q7QCU0   A0A3B0KKP3   A0A182PQN0   P34082   A0A2M4BE53   A0A3B0KR84   A0A0Q5TGA1   A0A2S2P3X5   A0A182V0J4   A0A0Q9XSX8   X2JAF4   E0VLC3   A0A182QS06   A0A2H8TP34   M9PGF6   A0A3B0K902   B0WB75   A0A0Q5TGV4   A0A1A9X4L6   A0A182KB15   A0A0R3P271   A0A0Q5T2Y3   A0A0R3P6T5   B4L6N6   A0A0R1EB60   A0A0M5JA94   Q29FP8   A0A182R4P0   B3NSV0   X1WIF0   A0A0R1EFX4  

PDB

2JLL     E-value=5.76981e-24,     Score=277

KEGG

101743546    K06491 neural cell adhesion molecule | (RefSeq) fasciclin-2-like

GO

GO:0016021   GO:0007155   GO:0016020   GO:0007399   GO:0030154   GO:0030017   GO:0035158   GO:0001746   GO:0035159   GO:0008038   GO:0042995   GO:0008582   GO:0007413   GO:0097482   GO:0031594   GO:1904800   GO:0043005   GO:0030424   GO:0007611   GO:0048803   GO:0007156   GO:0005886   GO:0048167   GO:0008355   GO:0042734   GO:0045211   GO:0048786   GO:0007528   GO:0048149   GO:0061174   GO:0008045   GO:0050803   GO:0007612   GO:0050808   GO:0007614   GO:0048667   GO:0036062   GO:0042059   GO:0031225   GO:0016319   GO:0005829   GO:0072499   GO:0072553   GO:0005737   GO:0005515   GO:0015074   GO:0006810   GO:0042626   GO:0016887   GO:0005622   GO:0003824  

Subcellular location

Membrane  
Cell membrane  

Length:

745

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

23.0072

Exp number, first 60 AAs:

0.0007

Total prob of N-in:

0.00282

outside

1  -  658

TMhelix

659  -  681

inside

682  -  745

 

 

Pi

256.114285

Theta

179.460882

Tajima's D

1.254289

CLR

0.06721

CSRT

0.727263636818159

Interpretation

Uncertain