Gene

KWMTBOMO11002

Annotation

Motile_sperm_domain-containing_protein_1_[Papilio_xuthus]

Location

Bomo_Chr18(-):9218889-9220862      View in EpiBrowser

Full name

Motile sperm domain-containing protein 1      

Location in the cell

Extracellular   Reliability : 2.542

CDS

ATGAAAAATTTTCCAGTGTTTGTATTTCCTGTTTCCTTAGAATTTTACCTTAACGCCAGACACACTCATAAACAGTTGTTAACTGTTTACAATCCTTATGATTTCTCTGTAAATTTCAAAGTATTATGTACGTCACCAAACAAGTTTACAGTCATCGACCCAGAGGGTGTGATCGCTCCACAAAGCTGTATTGATATTGTCGTACGTTACACACAACCATCTGTTTCACATTGCGACACAATAGAAAAATTCAGAATAACTATGTTTGACAGAAATACTCAGCAGGCTCTGGGAAAAAGAGACATTCCAACCAAACTTATTGAAGGTGAACCATCAAGTACGAACCAAGAAAGTTTTGGTGAAAACTTTCATCCAATAGCATCCAGAGCTGCACCAATTAGACCTACTGAGGATCATACAAAAATCTCATGTAATCATACAGGACACCACAGGGAGCATCAACCAACAAACATGGTAGCAGTAGCAGTGAGTATATGTTGTATAGCTGCATTGCTATTACCAACACAACCGGAACAAGCGGTAAAGTCACAGTGGCCTGACTGGCTTCATATTGGTGCCAATCTTAAGCTAGTCTTCTCATTTGTGCTCGGCCTTGTGAGCATGCTTGTTTTGAGACCATAG

Protein

MKNFPVFVFPVSLEFYLNARHTHKQLLTVYNPYDFSVNFKVLCTSPNKFTVIDPEGVIAPQSCIDIVVRYTQPSVSHCDTIEKFRITMFDRNTQQALGKRDIPTKLIEGEPSSTNQESFGENFHPIASRAAPIRPTEDHTKISCNHTGHHREHQPTNMVAVAVSICCIAALLLPTQPEQAVKSQWPDWLHIGANLKLVFSFVLGLVSMLVLRP

Description

Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation.

Keywords

Alternative splicing   Complete proteome   Differentiation   Endoplasmic reticulum   Golgi apparatus   Membrane   Polymorphism   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Motile sperm domain-containing protein 1
splice variant  In isoform 3.
sequence variant  In a breast cancer sample; somatic mutation.

Uniprot

A0A3S2NLF0   A0A194PN00   A0A2A4JXI9   A0A212FGA4   A0A2H1VH49   A0A194RRR4   + More
A0A0L7KZC6   A0A1Y1LHF6   A0A151WI74   A0A0J7KLR4   A0A195FUH1   A0A151J499   A0A195BMK4   A0A088AN96   A0A195CS47   A0A1B6D1E0   A0A067RBE0   E9JD99   A0A026X4F0   K7J0R9   A0A154PD15   A0A1B6LLY2   A0A1B6G7D8   A0A1B6JF13   A0A232FHW2   A0A069DPJ0   A0A2A3ECZ6   A0A2J7QXC2   A0A0L7RGY0   A0A023F104   A0A224XJC6   Q5FVZ0   A0A2I4CHV9   G3WDK0   A0A2P8Z5K4   A0A1A7YIB8   A0A2U9CC45   A0A3Q3WU09   A0A3B5BB59   A0A3B4YJA3   A0A3B4UF21   A0A3P8QXD7   A0A3P9BEN9   A0A3B4ES36   A0A3Q2UT88   I3KM32   A0A3Q2W9W0   A0A3P8WHJ9   A0A3B5PUH6   A0A3Q4IA31   Q7SYQ6   A0A3P8SKF5   A0A3Q2QRK8   A0A1S3K1U7   A0A3Q2XF55   A0A1A8PUU9   A0A1S3I591   A0A3Q1GFR9   A0A3B3ZI60   A0A3Q2EFB7   I3MB45   A0A3Q1J8F6   A0A0S7IV27   A0A096NWR3   F6YW20   H3CK54   A0A3Q3G6S9   A0A3Q3MMZ3   A0A2K6G5G0   A0A1V4KYN6   A0A2I0M4H4   G3WV50   A0A2G8LBX0   G3Q422   Q9UJG1-3   A0A2J8JSR7   A0A2J8WX20   A0A1L8F7Y4   H2SF10   A0A2R5LIU3   K7FQA3   F1NE32   D6WHS9   B5FYF0   A0A1U7S2Q2   H0YXI3   F7ATV6   A0A3L8SJT2   A0A2I0U874   G1MWD2   G5C255   A0A2K5X4V4   A0A2K5YMN1   A0A2K6NGX7   A0A2K5MRA0   A0A2K5K3S4   I0FTF8  

Pubmed

26354079    22118469    26227816    28004739    24845553    21282665    + More
24508170    30249741    20075255    28648823    26334808    25474469    20431018    21709235    29403074    25186727    24487278    23542700    25463417    17431167    15496914    23371554    29023486    14702039    15772651    15489334    16959974    26175344    27762356    21551351    17381049    15592404    18362917    19820115    17018643    20360741    18464734    30282656    20838655    21993625    25362486    25319552   

EMBL

RSAL01000298    RVE42802.1    KQ459604    KPI92500.1    NWSH01000474    PCG76140.1    + More
AGBW02008690    OWR52766.1    ODYU01002540    SOQ40170.1    KQ459765    KPJ20015.1    JTDY01004223    KOB68431.1    GEZM01058299    JAV71770.1    KQ983089    KYQ47553.1    LBMM01005846    KMQ91161.1    KQ981276    KYN43529.1    KQ980159    KYN17412.1    KQ976444    KYM86244.1    KQ977329    KYN03521.1    GEDC01017776    GEDC01008464    JAS19522.1    JAS28834.1    KK852618    KDR20152.1    GL771866    EFZ09164.1    KK107013    QOIP01000003    EZA62911.1    RLU24898.1    KQ434878    KZC09819.1    GEBQ01015235    JAT24742.1    GECZ01011526    JAS58243.1    GECU01009931    JAS97775.1    NNAY01000195    OXU30100.1    GBGD01002911    JAC85978.1    KZ288292    PBC29162.1    NEVH01009382    PNF33232.1    KQ414596    KOC69946.1    GBBI01004016    JAC14696.1    GFTR01003831    JAW12595.1    AAMC01014419    AAMC01014420    BC089697    BC121274    BC171186    BC171188    CR848211    AAH89697.1    AAI21275.1    AAI71186.1    CAJ83198.1    AEFK01230321    PYGN01000186    PSN51778.1    HADW01000720    HADX01007667    SBP29899.1    CP026255    AWP12442.1    AERX01038716    BC054306    AAH54306.1    HAEG01009534    SBR84759.1    AGTP01094771    GBYX01424356    JAO56880.1    AHZZ02038828    JSUE03046860    LSYS01001150    OPJ89496.1    AKCR02000041    PKK24581.1    PKK24582.1    PKK24583.1    AEFK01018786    MRZV01000133    PIK57753.1    AL137163    AK316570    Z83826    CH471107    BC005700    NBAG03000429    PNI25797.1    NDHI03003376    PNJ74298.1    CM004480    OCT67711.1    GGLE01005280    MBY09406.1    AGCU01035220    AGCU01035221    AGCU01035222    AADN05000020    KQ971321    EFA00064.1    DQ213949    ACH44061.1    ABQF01018374    AAPN01018545    AAPN01018546    AAPN01018547    QUSF01000018    RLW02628.1    KZ506018    PKU42221.1    JH172954    EHB15616.1    AQIA01087140    AQIA01087141    JV047663    AFI37734.1   

Proteomes

UP000283053    UP000053268    UP000218220    UP000007151    UP000053240    UP000037510    + More
UP000075809    UP000036403    UP000078541    UP000078492    UP000078540    UP000005203    UP000078542    UP000027135    UP000053097    UP000279307    UP000002358    UP000076502    UP000215335    UP000242457    UP000235965    UP000053825    UP000008143    UP000192220    UP000007648    UP000245037    UP000246464    UP000261620    UP000261400    UP000261360    UP000261420    UP000265100    UP000265160    UP000261460    UP000264840    UP000005207    UP000265120    UP000002852    UP000261580    UP000265080    UP000265000    UP000085678    UP000264820    UP000257200    UP000261520    UP000265020    UP000005215    UP000265040    UP000028761    UP000006718    UP000007303    UP000264800    UP000261660    UP000233160    UP000190648    UP000053872    UP000230750    UP000007635    UP000005640    UP000186698    UP000005226    UP000007267    UP000000539    UP000007266    UP000189705    UP000007754    UP000002279    UP000276834    UP000001645    UP000006813    UP000233100    UP000233140    UP000233200    UP000233060    UP000233080   

PRIDE

Q9UJG1   

Pfam

PF00635   Motile_Sperm        + More
PF15296   Codanin-1_C

Interpro

IPR008962   PapD-like_sf        + More
IPR039283   MOSPD1       
IPR013783   Ig-like_fold       
IPR000535   MSP_dom       
IPR040031   Codanin-1       
IPR028171   Codanin-1_C       

SUPFAM

SSF49354   SSF49354       

Gene 3D

2.60.40.10    

ProteinModelPortal

A0A3S2NLF0   A0A194PN00   A0A2A4JXI9   A0A212FGA4   A0A2H1VH49   A0A194RRR4   + More
A0A0L7KZC6   A0A1Y1LHF6   A0A151WI74   A0A0J7KLR4   A0A195FUH1   A0A151J499   A0A195BMK4   A0A088AN96   A0A195CS47   A0A1B6D1E0   A0A067RBE0   E9JD99   A0A026X4F0   K7J0R9   A0A154PD15   A0A1B6LLY2   A0A1B6G7D8   A0A1B6JF13   A0A232FHW2   A0A069DPJ0   A0A2A3ECZ6   A0A2J7QXC2   A0A0L7RGY0   A0A023F104   A0A224XJC6   Q5FVZ0   A0A2I4CHV9   G3WDK0   A0A2P8Z5K4   A0A1A7YIB8   A0A2U9CC45   A0A3Q3WU09   A0A3B5BB59   A0A3B4YJA3   A0A3B4UF21   A0A3P8QXD7   A0A3P9BEN9   A0A3B4ES36   A0A3Q2UT88   I3KM32   A0A3Q2W9W0   A0A3P8WHJ9   A0A3B5PUH6   A0A3Q4IA31   Q7SYQ6   A0A3P8SKF5   A0A3Q2QRK8   A0A1S3K1U7   A0A3Q2XF55   A0A1A8PUU9   A0A1S3I591   A0A3Q1GFR9   A0A3B3ZI60   A0A3Q2EFB7   I3MB45   A0A3Q1J8F6   A0A0S7IV27   A0A096NWR3   F6YW20   H3CK54   A0A3Q3G6S9   A0A3Q3MMZ3   A0A2K6G5G0   A0A1V4KYN6   A0A2I0M4H4   G3WV50   A0A2G8LBX0   G3Q422   Q9UJG1-3   A0A2J8JSR7   A0A2J8WX20   A0A1L8F7Y4   H2SF10   A0A2R5LIU3   K7FQA3   F1NE32   D6WHS9   B5FYF0   A0A1U7S2Q2   H0YXI3   F7ATV6   A0A3L8SJT2   A0A2I0U874   G1MWD2   G5C255   A0A2K5X4V4   A0A2K5YMN1   A0A2K6NGX7   A0A2K5MRA0   A0A2K5K3S4   I0FTF8  

KEGG

101736536    K20406 nitrogen permease regulator 3-like protein | (RefSeq) nitrogen permease regulator 3-like prot

GO

GO:0016021   GO:0005737   GO:0005634   GO:0000122   GO:0048471   GO:0045944   GO:0000139   GO:0005789   GO:0030154  

PANTHER

PTHR34441   PTHR28678  

Subcellular location

Endoplasmic reticulum membrane  
Golgi apparatus membrane  

Length:

213

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

38.26907

Exp number, first 60 AAs:

0.32293

Total prob of N-in:

0.74938

inside

1  -  156

TMhelix

157  -  174

outside

175  -  188

TMhelix

189  -  211

inside

212  -  213

 

 

Pi

228.656836

Theta

199.007471

Tajima's D

0.51252

CLR

0.011928

CSRT

0.513174341282936

Interpretation

Uncertain