Gene

KWMTBOMO10972

Annotation

UDP-glycosyltransferase_UGT44A1_[Bombyx_mori]

Location

Bomo_Chr18(-):8361008-8366656      View in EpiBrowser

Full name

UDP-glucuronosyltransferase      

Location in the cell

PlasmaMembrane   Reliability : 1.48

CDS

ATGTCAGATGCTCCGGCTTCGTACAGAGACATTTTATTAAGTGACAGACATGTGTATAAAGGTTTATCTTTTGAGTCAGTGATAGCAAGTGAAGTGTCGCGAGTGCCCTTTGAAACACTAGTGGCGACAAAAGCCGGCAACGATGATTGCAAAACTCTCATGAATAATAATCAAGTACTGCATTTGATTAGGACGCGGCCTCAATATGACGTCGTACTGGTCGAATCATTTAACAGTGACTGCGGAATAGCATTGGCGGCAAATTTGAGTGCGCCGTACATAGCATTGAACCCGAAGCCTTTACAGCCTTGGCACTACAATCGATTAGGTATCAATTTCAATGCAGCTTATGTAACCCAAACCGGCTTATCGTACGGAAAAAATCCTTGGTTCCTAGACCGAGTAAGAGGCTACATATTGTATCATATTACAAACTGGGTGTACTATGTTGGTTCACAAATCACAGATCACGTGTACTTATATAAATATTTAGGAGACAACCTTCCGTCTCTCGAAACGCTTGCGTCAAATGCTAGTTTAGTGTTTGTAAACACACATCAATCCGTTTTTGGGGGTATCTCCAGGCCTGATAACGTAATAGATATTGGCGGCATACACGTGAGACCTCCAAAAATCATTCCAACAGAAATCGAGAGATTTATAAACGAGGCTCAGCATGGTGTCGTCTATGTGAACTTGGGTTCAACGGTAAAAGATTCCACCCTGCCTGCCGAAAAGCTGGCTGAACTCCTCCTCACCTTCAGAAAACTACCCCACAGGGTACTTTGGAAATGGGACGGAGCAGCCATACAGAACCTGCCAAGAAATGTTATGACAATGAAGTGGCTACCCCAATATGACATTTTAAAGCACAAAAATGTAAAAGCACTCATCACTCATGCCGGTATACTGAGCACCATTGAAGCTATCGATGCTGGTATCCCTGTGGTGGCTATTCCCTTATTTGGAGATCAATATGGCAATGCAGCAGCAATGCAAGACGCCGGCATGGCGACCATAGTGCATTACCAGGATTTAAATAAAGAACATCTACTGGGTGCAGTCAATGAAGTTTTGGATGCGAAGAGGCAACAACAAGCAAAGCTGACGTCCAGGTTGTGGCACGACCGTTCTTTGTCGCCTTTGGAAAACGCCATCTATTGGACGGAATACGTAGCTCGATACCAAGGAGCTCCCAATCTTCAGCCTTTGTCGTCACAAGCACCACTATATCAACAATTGCAGCTAGACGTGTTATTGTTTGTGGCAATCGTTGTTTATATCCTGTTCTACGCTTTGTACAAAATCCTCAGAACCCTTTGCTGTTGTTGCTGTCGAGCTGATTCCGGAAACGGCGATGACGTAGGGGACACAAGGAAAAGAAAAAGAGTAAAATTCGAATGA

Protein

MSDAPASYRDILLSDRHVYKGLSFESVIASEVSRVPFETLVATKAGNDDCKTLMNNNQVLHLIRTRPQYDVVLVESFNSDCGIALAANLSAPYIALNPKPLQPWHYNRLGINFNAAYVTQTGLSYGKNPWFLDRVRGYILYHITNWVYYVGSQITDHVYLYKYLGDNLPSLETLASNASLVFVNTHQSVFGGISRPDNVIDIGGIHVRPPKIIPTEIERFINEAQHGVVYVNLGSTVKDSTLPAEKLAELLLTFRKLPHRVLWKWDGAAIQNLPRNVMTMKWLPQYDILKHKNVKALITHAGILSTIEAIDAGIPVVAIPLFGDQYGNAAAMQDAGMATIVHYQDLNKEHLLGAVNEVLDAKRQQQAKLTSRLWHDRSLSPLENAIYWTEYVARYQGAPNLQPLSSQAPLYQQLQLDVLLFVAIVVYILFYALYKILRTLCCCCCRADSGNGDDVGDTRKRKRVKFE

Catalytic Activity

glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP

Similarity

Belongs to the UDP-glycosyltransferase family.

Feature

chain  UDP-glucuronosyltransferase

Uniprot

G9LPV9   G9LPR5   A0A2A4JHL4   A0A3S2PBM0   A0A194PN21   A0A191T1N3   + More
A0A286MXP5   A0A2H1W091   A0A194RRT3   A0A0L7LRH5   A0A2H4WB74   A0A1L8D6F8   A0A212EWF8   S4PCR1   A0A3S2LHF3   A0A2J7R4V4   A0A2H4WB56   G9LPV6   D2A2V5   G9LPR2   A0A2J7R4W2   A0A2J7R4W8   A0A2A4JZV9   A0A194PHJ2   A0A1L8D6F4   A0A212EWE0   A0A0L7RH14   I4DM95   A0A2J7R4S8   A0A1Y1LIT5   A0A2H4WB57   A0A0A1WW96   A0A191T2H3   A0A191T1P6   G9LPV5   A0A067RAD1   A0A024AHN3   V5H2B2   A0A2H4WB66   A0A2P8ZG71   A0A087ZYR9   A0A2P8ZG63   A0A286MXP4   A0A0K8UGE5   A0A212EWH2   A0A0K8UM10   G9LPV7   A0A2P8ZG78   A0A182NE44   A0A194RRD0   A0A182PJ64   A0A1W4WYE4   A0A182W9Q0   A0A1I8NWG2   A0A182UEM4   A0A182V6Z3   A0A1S4GXF8   A0A182WT93   J9K7F3   A0A1Y1LL43   G9LPR3   A0A1W4WMF1   A0A182HV86   A0A2J7R4W5   A0A182YGV2   A0A1B6KV12   B3NL92   A0A1L8D6L6   B4JDJ1   A0A182RBM8   A0A1I8NWF4   W8AR85   A0A2J7R4T0   A0A067QGQ4   A0A2P8ZG70   A0A194RRL0   A0A1I8N2C0   T1PFI1   Q9VJ46   D6W4K8   A0A0J9R3P5   B4Q8Y7   A0A1W4VM86   A0A1W4V9G2   A0A1W4VMW4   B4G9A2   A0A139WIW7   B4G9A5   A0A084VP43   A0A182QSB1   A0A1W4V9E9   E2B0N7   A0A0C9RNU1   B4I5L1   A0A026WYL1   Q29MG5   A0A1W4WMC9   A0A034V788   A0A291PQF1   B4Q8Y8  

EC Number

2.4.1.17

Pubmed

22155036    26354079    19954531    25299618    26227816    29027758    + More
22118469    23622113    18362917    19820115    22651552    28004739    25830018    24845553    24698447    29403074    12364791    25244985    17994087    24495485    25315136    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    24438588    20798317    24508170    15632085    25348373   

EMBL

JQ070266    AEW43182.1    JQ070222    AEW43138.1    NWSH01001552    PCG70882.1    + More
RSAL01000119    RVE46733.1    KQ459604    KPI92520.1    KU680308    ANI22014.1    MF684363    ASX93997.1    ODYU01005418    SOQ46242.1    KQ459765    KPJ20035.1    JTDY01000310    KOB77761.1    KY202936    AUC64280.1    GEYN01000098    JAV02031.1    AGBW02012000    OWR45816.1    GAIX01004036    JAA88524.1    RVE46732.1    NEVH01007402    PNF35866.1    KY202929    AUC64273.1    JQ070263    AEW43179.1    KQ971338    EFA02977.2    JQ070219    AEW43135.1    PNF35872.1    PNF35870.1    NWSH01000347    PCG77184.1    KPI92518.1    GEYN01000096    JAV02033.1    OWR45818.1    KQ414596    KOC70104.1    AK402413    BAM19035.1    PNF35836.1    GEZM01054555    JAV73559.1    KY202930    AUC64274.1    GBXI01011391    JAD02901.1    KU680305    ANI22011.1    KU680306    ANI22012.1    JQ070262    AEW43178.1    KK852590    KDR20744.1    KF777118    AHY99689.1    GALX01001513    JAB66953.1    KY202934    AUC64278.1    PYGN01000068    PSN55491.1    PSN55493.1    MF684362    ASX93996.1    GDHF01026592    JAI25722.1    OWR45817.1    GDHF01024708    JAI27606.1    JQ070264    AEW43180.1    PSN55501.1    KPJ20032.1    AAAB01008964    ABLF02020524    ABLF02020525    GEZM01054556    JAV73558.1    JQ070220    AEW43136.1    APCN01002501    PNF35871.1    GEBQ01024697    JAT15280.1    CH954179    EDV54742.1    GEYN01000094    JAV02035.1    CH916368    EDW03361.1    GAMC01019493    GAMC01019492    GAMC01019491    JAB87063.1    PNF35837.1    KK853490    KDR07235.1    PSN55494.1    KPJ20034.1    KA647552    AFP62181.1    AE014134    AY051629    AAF53709.1    AAK93053.1    BT124908    ADH29876.1    CM002910    KMY90882.1    CM000361    EDX05419.1    KMY90880.1    CH479180    EDW28932.1    KYB27856.1    EDW28935.1    ATLV01014974    KE524999    KFB39737.1    AXCN02000871    GL444666    EFN60709.1    GBYB01008756    JAG78523.1    CH480822    EDW55667.1    KK107063    EZA61120.1    CH379060    EAL33728.1    GAKP01020965    JAC37987.1    KY860727    ATL15306.1    EDX05420.1    KMY90883.1   

Proteomes

UP000218220    UP000283053    UP000053268    UP000053240    UP000037510    UP000007151    + More
UP000235965    UP000007266    UP000053825    UP000027135    UP000245037    UP000005203    UP000075884    UP000075885    UP000192223    UP000075920    UP000095300    UP000075902    UP000075903    UP000076407    UP000007819    UP000075840    UP000076408    UP000008711    UP000001070    UP000075900    UP000095301    UP000000803    UP000000304    UP000192221    UP000008744    UP000030765    UP000075886    UP000000311    UP000001292    UP000053097    UP000001819   

PRIDE

G9LPV9    G9LPV6    G9LPV5    G9LPV7    Q9VJ46    D6W4K8    + More

Pfam

PF00201   UDPGT

Interpro

IPR035595   UDP_glycos_trans_CS        + More
IPR002213   UDP_glucos_trans       
IPR018506   Cyt_B5_heme-BS       

ProteinModelPortal

G9LPV9   G9LPR5   A0A2A4JHL4   A0A3S2PBM0   A0A194PN21   A0A191T1N3   + More
A0A286MXP5   A0A2H1W091   A0A194RRT3   A0A0L7LRH5   A0A2H4WB74   A0A1L8D6F8   A0A212EWF8   S4PCR1   A0A3S2LHF3   A0A2J7R4V4   A0A2H4WB56   G9LPV6   D2A2V5   G9LPR2   A0A2J7R4W2   A0A2J7R4W8   A0A2A4JZV9   A0A194PHJ2   A0A1L8D6F4   A0A212EWE0   A0A0L7RH14   I4DM95   A0A2J7R4S8   A0A1Y1LIT5   A0A2H4WB57   A0A0A1WW96   A0A191T2H3   A0A191T1P6   G9LPV5   A0A067RAD1   A0A024AHN3   V5H2B2   A0A2H4WB66   A0A2P8ZG71   A0A087ZYR9   A0A2P8ZG63   A0A286MXP4   A0A0K8UGE5   A0A212EWH2   A0A0K8UM10   G9LPV7   A0A2P8ZG78   A0A182NE44   A0A194RRD0   A0A182PJ64   A0A1W4WYE4   A0A182W9Q0   A0A1I8NWG2   A0A182UEM4   A0A182V6Z3   A0A1S4GXF8   A0A182WT93   J9K7F3   A0A1Y1LL43   G9LPR3   A0A1W4WMF1   A0A182HV86   A0A2J7R4W5   A0A182YGV2   A0A1B6KV12   B3NL92   A0A1L8D6L6   B4JDJ1   A0A182RBM8   A0A1I8NWF4   W8AR85   A0A2J7R4T0   A0A067QGQ4   A0A2P8ZG70   A0A194RRL0   A0A1I8N2C0   T1PFI1   Q9VJ46   D6W4K8   A0A0J9R3P5   B4Q8Y7   A0A1W4VM86   A0A1W4V9G2   A0A1W4VMW4   B4G9A2   A0A139WIW7   B4G9A5   A0A084VP43   A0A182QSB1   A0A1W4V9E9   E2B0N7   A0A0C9RNU1   B4I5L1   A0A026WYL1   Q29MG5   A0A1W4WMC9   A0A034V788   A0A291PQF1   B4Q8Y8  

PDB

2O6L     E-value=3.18996e-23,     Score=269

KEGG

100862820    K00699 glucuronosyltransferase [EC:2.4.1.17] | (RefSeq) UGT44A1; UDP-glycosyltransferase UGT44A1

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00830    Retinol metabolism - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0015020   GO:0016758   GO:0016740   GO:0020037   GO:0008194   GO:0043231   GO:0008152   GO:0016787   GO:0030163   GO:0015935   GO:0051603   GO:0051028   GO:0005622   GO:0006810   GO:0003824  

Subcellular location

Membrane  

Length:

467

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

23.05577

Exp number, first 60 AAs:

0.00042

Total prob of N-in:

0.09185

outside

1  -  417

TMhelix

418  -  437

inside

438  -  467

 

 

Pi

230.942903

Theta

158.475064

Tajima's D

0.927218

CLR

0.023356

CSRT

0.64276786160692

Interpretation

Uncertain