Gene

KWMTBOMO10971

Annotation

UDP-glycosyltransferase_UGT42A1_[Bombyx_mori]

Location

Bomo_Chr18(-):8348093-8350826      View in EpiBrowser

Full name

UDP-glucuronosyltransferase      

Location in the cell

Cytoplasmic   Reliability : 2.065

CDS

ATGCTTGCCAATAAGGAGGTACAGGACTTGTGGAAAAATAAAATACATTTTGACGTTGCTGTTGTCGAACAGTTTAACAGTGATTGTGCATTAGGGCTCGCTTATAAATTAGGAATACCAGTGGTCGGCACGAACTCCCACGTTCTTATGCCTTACCAATACGAAAGATTCGGCATACATTACAATCCCTCGTATATGACATTCCAATTCTTGGAAGGCGGAACGAAACCTACACTGTTCCAACGTATTGAAAGAACAATATTCCATCACTACTATAATTTTATTTTCGAATACCTCTCTCAAAGAACCAATCAAAATACACTGGCGCAATACTTCGATGACATTCCACCTTTAAACGAATTAGCTCGTGAAATCAAAATAATGCTTTTCTATCATAACTTTGTGCTATCCGGTCCTAATATTTTACCTTCAAATGTAAAAGAAGTCGGGGGCTACCACGTTGCTCAACCCAAGGAACTCCGTCCGGATGTCAAAAAGTTTATCGAGGAATCTGAGCACGGCATTATTTATATTAGTTTTGGATCGATGCTAAAAGCTGCGGCTACTTCATTAGATAAAATCGAGGCTATATTGGGTGCTGTCGCTGAATTACCTCAGAGAGTGATATGGAAATGGGAGGAAGGAACACTACCCGGCAACCCTAAGAATATTTTCATATCAAACTGGCTTCCTCAAAACGATATTTTAGCCCATCCGAAAGTACTAGCTTTCTATTCGCATTGCGGTCAGCTAGGGACCACGGAGGCTATCTATCATGGAGTTCCTGTTGTGGGAATGCCGGTCTTCGGGGACCAGCCTGCAAATGCGGCGGCCGTTGAAGAGAGTGGTTTAGGTGTCCAAATACAAATCGAAGATTTGACTAAAGAGAACCTCTTAGGGAAATTAAGAACCGTTTTGAATCCAGAGTTTAGAAAAAGGGTGAAATTTATATCGAAAGCGTGGAACGACCGTCCCGTAAAAGCAATGGATAGTGCAATTTTCTGGACAGAGTTCGCAGCCAAATATACATAA

Protein

MLANKEVQDLWKNKIHFDVAVVEQFNSDCALGLAYKLGIPVVGTNSHVLMPYQYERFGIHYNPSYMTFQFLEGGTKPTLFQRIERTIFHHYYNFIFEYLSQRTNQNTLAQYFDDIPPLNELAREIKIMLFYHNFVLSGPNILPSNVKEVGGYHVAQPKELRPDVKKFIEESEHGIIYISFGSMLKAAATSLDKIEAILGAVAELPQRVIWKWEEGTLPGNPKNIFISNWLPQNDILAHPKVLAFYSHCGQLGTTEAIYHGVPVVGMPVFGDQPANAAAVEESGLGVQIQIEDLTKENLLGKLRTVLNPEFRKRVKFISKAWNDRPVKAMDSAIFWTEFAAKYT

Catalytic Activity

glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP

Similarity

Belongs to the UDP-glycosyltransferase family.

Feature

chain  UDP-glucuronosyltransferase

Uniprot

G9LPV5   G9LPV6   A0A191T1P6   G9LPR3   A0A194RRL0   A0A3S2LHF3   + More
A0A194PIG8   A0A2H4WB57   A0A2H4WB56   H9JYK2   A0A1L8D6F4   I4DM95   A0A2A4JZV9   A0A191T2H3   A0A2H1W091   G9LPR2   A0A194RQ88   A0A024AHN3   A0A212EWE0   A0A194PHJ2   A0A212EWH2   G9LPV7   A0A194RRD0   A0A2H4WB66   A0A1L8D6L6   A0A286MXP4   A0A0L7LRH5   A0A2P8ZG78   A0A067RAD1   A0A2J7R4W8   A0A2J7R4S8   A0A1I8N2C0   T1PFI1   A0A3Q0JH20   A0A3Q0JLK0   A0A1I8NWG2   A0A2J7R4W4   A0A034V788   A0A1I8NWF4   A0A2J7R4V4   G9LPR5   A0A2P8ZG63   A0A2A4JHL4   A0A0K8VSF2   Q17HG0   A0A1S4F2K0   W8AR85   S4PCR1   D2A2V5   G9LPV8   G9LPR4   A0A0K8UGE5   B3NL92   A0A0K8UM10   A0A182GI26   A0A286MXP5   B4JDJ0   A0A3S2PBM0   A0A2P8ZG71   B0WBP4   A0A191T1N2   A0A191T1N3   A0A182PJ64   A0A212EKS8   A0A1Q3FPW9   B4LT82   A0A0K8UJA2   A0A067QGQ4   A0A2P8ZG70   A0A1Q3FPY1   A0A182NE44   A0A194Q839   B3NL93   A0A182W9Q0   B4KH53   B3MKL2   A0A2H4WB69   A0A182UEM4   A0A1S4GXF8   A0A0M4EQP2   A0A0M4EH80   A0A182HV86   A0A0P8XVU8   A0A182WT93   A0A182V6Z3   A0A182RBM8   B4P9Y7   A0A084VP43   Q9VJ46   G9LPV9   B4MWT6   A0A182YGV2   D6W4K8   A0A2J7R4T0   B4MWT5   A0A336KCF6   A0A3B0JEG0   B4JDJ1   B4Q8Y7   Q9VJ45  

EC Number

2.4.1.17

Pubmed

22155036    26354079    29027758    19121390    22651552    24698447    + More
22118469    19954531    25299618    26227816    29403074    24845553    25315136    25348373    17510324    24495485    23622113    18362917    19820115    17994087    26483478    18057021    12364791    17550304    24438588    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25244985    22936249   

EMBL

JQ070262    AEW43178.1    JQ070263    AEW43179.1    KU680306    ANI22012.1    + More
JQ070220    AEW43136.1    KQ459765    KPJ20034.1    RSAL01000119    RVE46732.1    KQ459604    KPI92519.1    KY202930    AUC64274.1    KY202929    AUC64273.1    BABH01043998    GEYN01000096    JAV02033.1    AK402413    BAM19035.1    NWSH01000347    PCG77184.1    KU680305    ANI22011.1    ODYU01005418    SOQ46242.1    JQ070219    AEW43135.1    KPJ20033.1    KF777118    AHY99689.1    AGBW02012000    OWR45818.1    KPI92518.1    OWR45817.1    JQ070264    AEW43180.1    KPJ20032.1    KY202934    AUC64278.1    GEYN01000094    JAV02035.1    MF684362    ASX93996.1    JTDY01000310    KOB77761.1    PYGN01000068    PSN55501.1    KK852590    KDR20744.1    NEVH01007402    PNF35870.1    PNF35836.1    KA647552    AFP62181.1    PNF35869.1    GAKP01020965    JAC37987.1    PNF35866.1    JQ070222    AEW43138.1    PSN55493.1    NWSH01001552    PCG70882.1    GDHF01010498    JAI41816.1    CH477249    EAT46102.1    GAMC01019493    GAMC01019492    GAMC01019491    JAB87063.1    GAIX01004036    JAA88524.1    KQ971338    EFA02977.2    JQ070265    AEW43181.1    JQ070221    AEW43137.1    GDHF01026592    JAI25722.1    CH954179    EDV54742.1    GDHF01024708    JAI27606.1    JXUM01065169    KQ562333    KXJ76125.1    MF684363    ASX93997.1    CH916368    EDW03360.1    RVE46733.1    PSN55491.1    DS231880    EDS42579.1    KU680307    ANI22013.1    KU680308    ANI22014.1    AGBW02014216    OWR42090.1    GFDL01005396    JAV29649.1    CH940649    EDW64924.1    GDHF01025575    JAI26739.1    KK853490    KDR07235.1    PSN55494.1    GFDL01005384    JAV29661.1    KQ459302    KPJ01707.1    EDV54743.1    CH933807    EDW13270.2    CH902620    EDV31565.1    KPU73480.1    KY202942    AUC64286.1    AAAB01008964    CP012523    ALC39362.1    ALC40242.1    APCN01002501    KPU73481.1    CM000158    EDW90328.1    ATLV01014974    KE524999    KFB39737.1    AE014134    AY051629    AAF53709.1    AAK93053.1    JQ070266    AEW43182.1    CH963857    EDW76575.1    BT124908    ADH29876.1    PNF35837.1    EDW76574.1    UFQS01000219    UFQT01000219    SSX01542.1    SSX21922.1    OUUW01000004    SPP79043.1    EDW03361.1    CM000361    CM002910    EDX05419.1    KMY90880.1    AY069532    AAF53710.2    AAF53711.2    AAL39677.1   

Proteomes

UP000053240    UP000283053    UP000053268    UP000005204    UP000218220    UP000007151    + More
UP000037510    UP000245037    UP000027135    UP000235965    UP000095301    UP000079169    UP000095300    UP000008820    UP000007266    UP000008711    UP000069940    UP000249989    UP000001070    UP000002320    UP000075885    UP000008792    UP000075884    UP000075920    UP000009192    UP000007801    UP000075902    UP000092553    UP000075840    UP000076407    UP000075903    UP000075900    UP000002282    UP000030765    UP000000803    UP000007798    UP000076408    UP000268350    UP000000304   

PRIDE

G9LPV5    G9LPV6    H9JYK2    G9LPV7    G9LPV8    Q9VJ46    + More
G9LPV9    D6W4K8    Q9VJ45   

Pfam

PF00201   UDPGT

Interpro

IPR002213   UDP_glucos_trans        + More
IPR035595   UDP_glycos_trans_CS       

ProteinModelPortal

G9LPV5   G9LPV6   A0A191T1P6   G9LPR3   A0A194RRL0   A0A3S2LHF3   + More
A0A194PIG8   A0A2H4WB57   A0A2H4WB56   H9JYK2   A0A1L8D6F4   I4DM95   A0A2A4JZV9   A0A191T2H3   A0A2H1W091   G9LPR2   A0A194RQ88   A0A024AHN3   A0A212EWE0   A0A194PHJ2   A0A212EWH2   G9LPV7   A0A194RRD0   A0A2H4WB66   A0A1L8D6L6   A0A286MXP4   A0A0L7LRH5   A0A2P8ZG78   A0A067RAD1   A0A2J7R4W8   A0A2J7R4S8   A0A1I8N2C0   T1PFI1   A0A3Q0JH20   A0A3Q0JLK0   A0A1I8NWG2   A0A2J7R4W4   A0A034V788   A0A1I8NWF4   A0A2J7R4V4   G9LPR5   A0A2P8ZG63   A0A2A4JHL4   A0A0K8VSF2   Q17HG0   A0A1S4F2K0   W8AR85   S4PCR1   D2A2V5   G9LPV8   G9LPR4   A0A0K8UGE5   B3NL92   A0A0K8UM10   A0A182GI26   A0A286MXP5   B4JDJ0   A0A3S2PBM0   A0A2P8ZG71   B0WBP4   A0A191T1N2   A0A191T1N3   A0A182PJ64   A0A212EKS8   A0A1Q3FPW9   B4LT82   A0A0K8UJA2   A0A067QGQ4   A0A2P8ZG70   A0A1Q3FPY1   A0A182NE44   A0A194Q839   B3NL93   A0A182W9Q0   B4KH53   B3MKL2   A0A2H4WB69   A0A182UEM4   A0A1S4GXF8   A0A0M4EQP2   A0A0M4EH80   A0A182HV86   A0A0P8XVU8   A0A182WT93   A0A182V6Z3   A0A182RBM8   B4P9Y7   A0A084VP43   Q9VJ46   G9LPV9   B4MWT6   A0A182YGV2   D6W4K8   A0A2J7R4T0   B4MWT5   A0A336KCF6   A0A3B0JEG0   B4JDJ1   B4Q8Y7   Q9VJ45  

PDB

2O6L     E-value=5.41694e-27,     Score=300

KEGG

100862817    K00699 glucuronosyltransferase [EC:2.4.1.17] | (RefSeq) UGT42A1; UDP-glycosyltransferase UGT42A1

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00830    Retinol metabolism - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016758   GO:0016021   GO:0015020   GO:0016740   GO:0006011   GO:0005783   GO:0008194   GO:0006805   GO:0008152   GO:0016787   GO:0030163   GO:0015935   GO:0051603   GO:0051028   GO:0005622   GO:0006810   GO:0003824  

Subcellular location

Membrane  

Length:

343

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0775099999999999

Exp number, first 60 AAs:

0.06965

Total prob of N-in:

0.01958

outside

1  -  343

 

 

Pi

208.156652

Theta

126.242138

Tajima's D

0.651464

CLR

0.720115

CSRT

0.566771661416929

Interpretation

Uncertain