Gene

KWMTBOMO10970

Pre Gene Modal

BGIBMGA014622

Annotation

UDP-glycosyltransferase_UGT42A2_precursor_[Bombyx_mori]

Location

Bomo_Chr18(-):8333835-8341836      View in EpiBrowser

Full name

UDP-glucuronosyltransferase      

Location in the cell

PlasmaMembrane   Reliability : 3.127

CDS

ATGAGATTTAGCGTTACACTTGAACTTTTGTTGGTTATCTTTTGTTTGCATAAAACTGAAGTGTGTTCATTGAATATTTTGGGTCTGTTCCCGTATCCTGGAAAAAGTCACTTCTTTGTATTTCGTCCATATTTGGAAGAATTGGCCAAAAGGGGCCATAACGTGACTGTTGTATCGCATTTTCCGCAGAAAGTGCCTCACCAAAATTATCATGACATTAGTTTGGCGGGAAAAACGAAAATTTTAGAAGACGTCTTCCCATTGCAAAAGTCTTATTGGACTGTAATTAATATTTTGCATTTTATTCTCGAAAAAGGAAATAGTGACTGCAAAACATTATTAAATCATGAAGATGTCCAAAAACTGTGGAAAACTAAACAGCACTTTGACCTTGTGGTTACGGAACAATTTGTGAGTGACTGTAGTTTGGGTCTTGCCTATAAATTGGGGGCTCCAGCAATCGGGATCAACTCACACGTGATTGTTCCTTGGCAGTACGAGCGTTTGGGTATCCAGTACCATCCTGCTTACGTACCATTCCTGTTCCTGGAAGGCGGATCCAAACCGTCACTGTACCAGAGATTTGAAAGGACCATTCTTCACAATTATTTTAATTACCTATACAAATATAAATATCAACCGATCGACGAAGAGACACTCGCTGAATATTTTGATGATATTCCGCCTTTGGATTATTTGGCTCGAGAAATGAAATTGTTACTTTTATATCACAATTTTGTATTATACGGGTCTAACTTGCTACCTTCGAACGTTATTGAAGTGGGAGGATATCATGTAGCGAAGCCACAGGAATTACCTCAAGATTTGAAAATATTTATTGAGGAATCCGAGCATGGTGTAATCTATATTAGTTTTGGATCAATGTTACGTGCCAGTTCCACTCCGCGTGATAAGCTTGAGGCTATAATTGCTGCTCTGTCGGAGTTACCACAAAGGGTTATATGGAAATGGGATGAAGCATCGTTACCTGGAAACCCGAAGAATATACTGCTTTCAAAATGGCTACCGCAAAACGATATTTTAGCTCATACGAAAGTGCTGGCGTTTTTCTCTCACTGTGGACTACTGGGTACCACCGAAGCTATTTACCATGGTGTACCCATGATCGGCATGCCTGTCTTTGGGGACCAACCTGGGAATGCCGCTGCTATCGAAGAAAGTGGCCTTGGACTCCAAATTCAAATCACGGAACTTAGCAAAGAAGTTCTGCTAGAAAAATTCCGGACCATTTTAAACCCTGAATTCAGGAAGAAAGTGAAATTTATATCTATGGCCTGGAAAGATCGTCCTATCTCAGCTATAGACAACGCCGTTTTCTGGACGGAATTTGCAGCCAAGTATAGCAATATCACGTTTCGAAGTAGATCAGCTGATGTACCATTATACCAATATTTGTATTTAGACGTGTTTGTTGTCTTTACGGCTATCGTTATATGTATTGGTTTTCTAGTTAATTACATTATAACATTGTTACTACGTCGTATTGCAAAGAAATTCAAACAAAACTAG

Protein

MRFSVTLELLLVIFCLHKTEVCSLNILGLFPYPGKSHFFVFRPYLEELAKRGHNVTVVSHFPQKVPHQNYHDISLAGKTKILEDVFPLQKSYWTVINILHFILEKGNSDCKTLLNHEDVQKLWKTKQHFDLVVTEQFVSDCSLGLAYKLGAPAIGINSHVIVPWQYERLGIQYHPAYVPFLFLEGGSKPSLYQRFERTILHNYFNYLYKYKYQPIDEETLAEYFDDIPPLDYLAREMKLLLLYHNFVLYGSNLLPSNVIEVGGYHVAKPQELPQDLKIFIEESEHGVIYISFGSMLRASSTPRDKLEAIIAALSELPQRVIWKWDEASLPGNPKNILLSKWLPQNDILAHTKVLAFFSHCGLLGTTEAIYHGVPMIGMPVFGDQPGNAAAIEESGLGLQIQITELSKEVLLEKFRTILNPEFRKKVKFISMAWKDRPISAIDNAVFWTEFAAKYSNITFRSRSADVPLYQYLYLDVFVVFTAIVICIGFLVNYIITLLLRRIAKKFKQN

Catalytic Activity

glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP

Similarity

Belongs to the UDP-glycosyltransferase family.

Feature

chain  UDP-glucuronosyltransferase

Uniprot

G9LPV6   H9JYK2   G9LPV5   A0A191T1P6   G9LPR3   A0A2H1W091   + More
A0A3S2LHF3   A0A194PHJ2   A0A1L8D6F4   A0A2H4WB57   A0A2H4WB56   A0A191T2H3   A0A2A4JZV9   A0A024AHN3   G9LPR2   A0A194RRD0   A0A212EWE0   G9LPV7   A0A2H4WB66   A0A212EWH2   A0A1L8D6L6   A0A286MXP4   I4DM95   A0A194RQ88   A0A194RRL0   A0A194PIG8   A0A0L7LRH5   A0A067RAD1   A0A2J7R4W8   A0A2J7R4S8   A0A2P8ZG78   D2A2V5   A0A2P8ZG63   A0A191T1N2   A0A182V6Z3   A0A182UEM4   A0A2A4JYW3   A0A1I8N2C0   A0A182PJ64   A0A2H1VZI1   A0A182WT93   A0A1L8D6F8   A0A182NE44   A0A1S4GXF8   T1PFI1   A0A182W9Q0   A0A2J7R4V4   A0A2H4WB74   A0A182HV86   A0A0K8VSF2   A0A336KCF6   A0A2J7R4T0   A0A182YGV2   A0A2J7R4W4   A0A084VP43   G9LPR4   A0A286MXP5   A0A0C9RNU1   A0A182IX39   A0A1I8NWF4   A0A182SC34   G9LPR5   A0A0K8UJA2   A0A2J7R4W2   A0A182RBM8   A0A2P8ZG71   A0A0K8UM10   A0A0K8UGE5   A0A2A4JHL4   A0A2P8ZG70   G9LPV8   A0A2J7QFA7   B0WBP4   A0A2A4JZH0   A0A1B6KXR8   A0A1S4F2K0   Q17HG0   A0A1Q3FPW9   A0A3S2PBM0   A0A1B6K0J6   A0A182QSB1   A0A1Q3FPY1   A0A034V788   G9LPV9   A0A2M3Z1Z1   Q7Q3K2   A0A182GI26   W8AR85   A0A182F4M1   V5H2B2   A0A2M3Z1Z8   A0A2J7QFA8   A0A1B6DGT0   A0A1B6FAC1   A0A067RIR8   A0A0A1WW96   A0A1B6K3R7   W5J9T2   A0A1W4WMC9  

EC Number

2.4.1.17

Pubmed

22155036    19121390    26354079    29027758    24698447    22118469    + More
19954531    25299618    22651552    26227816    24845553    29403074    18362917    19820115    25315136    12364791    25244985    24438588    17510324    25348373    26483478    24495485    25830018    20920257    23761445   

EMBL

JQ070263    AEW43179.1    BABH01043998    JQ070262    AEW43178.1    KU680306    + More
ANI22012.1    JQ070220    AEW43136.1    ODYU01005418    SOQ46242.1    RSAL01000119    RVE46732.1    KQ459604    KPI92518.1    GEYN01000096    JAV02033.1    KY202930    AUC64274.1    KY202929    AUC64273.1    KU680305    ANI22011.1    NWSH01000347    PCG77184.1    KF777118    AHY99689.1    JQ070219    AEW43135.1    KQ459765    KPJ20032.1    AGBW02012000    OWR45818.1    JQ070264    AEW43180.1    KY202934    AUC64278.1    OWR45817.1    GEYN01000094    JAV02035.1    MF684362    ASX93996.1    AK402413    BAM19035.1    KPJ20033.1    KPJ20034.1    KPI92519.1    JTDY01000310    KOB77761.1    KK852590    KDR20744.1    NEVH01007402    PNF35870.1    PNF35836.1    PYGN01000068    PSN55501.1    KQ971338    EFA02977.2    PSN55493.1    KU680307    ANI22013.1    PCG77205.1    SOQ46241.1    GEYN01000098    JAV02031.1    AAAB01008964    KA647552    AFP62181.1    PNF35866.1    KY202936    AUC64280.1    APCN01002501    GDHF01010498    JAI41816.1    UFQS01000219    UFQT01000219    SSX01542.1    SSX21922.1    PNF35837.1    PNF35869.1    ATLV01014974    KE524999    KFB39737.1    JQ070221    AEW43137.1    MF684363    ASX93997.1    GBYB01008756    JAG78523.1    JQ070222    AEW43138.1    GDHF01025575    JAI26739.1    PNF35872.1    PSN55491.1    GDHF01024708    JAI27606.1    GDHF01026592    JAI25722.1    NWSH01001552    PCG70882.1    PSN55494.1    JQ070265    AEW43181.1    NEVH01015300    PNF27275.1    DS231880    EDS42579.1    PCG77209.1    GEBQ01023933    JAT16044.1    CH477249    EAT46102.1    GFDL01005396    JAV29649.1    RVE46733.1    GECU01002730    JAT04977.1    AXCN02000871    GFDL01005384    JAV29661.1    GAKP01020965    JAC37987.1    JQ070266    AEW43182.1    GGFM01001770    MBW22521.1    EAA12774.4    JXUM01065169    KQ562333    KXJ76125.1    GAMC01019493    GAMC01019492    GAMC01019491    JAB87063.1    GALX01001513    JAB66953.1    GGFM01001806    MBW22557.1    PNF27276.1    GEDC01012446    JAS24852.1    GECZ01022678    JAS47091.1    KK852607    KDR20346.1    GBXI01011391    JAD02901.1    GECU01001605    JAT06102.1    ADMH02001962    ETN60168.1   

Proteomes

UP000005204    UP000283053    UP000053268    UP000218220    UP000053240    UP000007151    + More
UP000037510    UP000027135    UP000235965    UP000245037    UP000007266    UP000075903    UP000075902    UP000095301    UP000075885    UP000076407    UP000075884    UP000075920    UP000075840    UP000076408    UP000030765    UP000075880    UP000095300    UP000075901    UP000075900    UP000002320    UP000008820    UP000075886    UP000007062    UP000069940    UP000249989    UP000069272    UP000000673    UP000192223   

PRIDE

G9LPV6    H9JYK2    G9LPV5    G9LPV7    G9LPV8    G9LPV9    + More

Pfam

PF00201   UDPGT

Interpro

IPR002213   UDP_glucos_trans        + More
IPR035595   UDP_glycos_trans_CS       

ProteinModelPortal

G9LPV6   H9JYK2   G9LPV5   A0A191T1P6   G9LPR3   A0A2H1W091   + More
A0A3S2LHF3   A0A194PHJ2   A0A1L8D6F4   A0A2H4WB57   A0A2H4WB56   A0A191T2H3   A0A2A4JZV9   A0A024AHN3   G9LPR2   A0A194RRD0   A0A212EWE0   G9LPV7   A0A2H4WB66   A0A212EWH2   A0A1L8D6L6   A0A286MXP4   I4DM95   A0A194RQ88   A0A194RRL0   A0A194PIG8   A0A0L7LRH5   A0A067RAD1   A0A2J7R4W8   A0A2J7R4S8   A0A2P8ZG78   D2A2V5   A0A2P8ZG63   A0A191T1N2   A0A182V6Z3   A0A182UEM4   A0A2A4JYW3   A0A1I8N2C0   A0A182PJ64   A0A2H1VZI1   A0A182WT93   A0A1L8D6F8   A0A182NE44   A0A1S4GXF8   T1PFI1   A0A182W9Q0   A0A2J7R4V4   A0A2H4WB74   A0A182HV86   A0A0K8VSF2   A0A336KCF6   A0A2J7R4T0   A0A182YGV2   A0A2J7R4W4   A0A084VP43   G9LPR4   A0A286MXP5   A0A0C9RNU1   A0A182IX39   A0A1I8NWF4   A0A182SC34   G9LPR5   A0A0K8UJA2   A0A2J7R4W2   A0A182RBM8   A0A2P8ZG71   A0A0K8UM10   A0A0K8UGE5   A0A2A4JHL4   A0A2P8ZG70   G9LPV8   A0A2J7QFA7   B0WBP4   A0A2A4JZH0   A0A1B6KXR8   A0A1S4F2K0   Q17HG0   A0A1Q3FPW9   A0A3S2PBM0   A0A1B6K0J6   A0A182QSB1   A0A1Q3FPY1   A0A034V788   G9LPV9   A0A2M3Z1Z1   Q7Q3K2   A0A182GI26   W8AR85   A0A182F4M1   V5H2B2   A0A2M3Z1Z8   A0A2J7QFA8   A0A1B6DGT0   A0A1B6FAC1   A0A067RIR8   A0A0A1WW96   A0A1B6K3R7   W5J9T2   A0A1W4WMC9  

PDB

2O6L     E-value=2.38262e-29,     Score=322

KEGG

100862818    K00699 glucuronosyltransferase [EC:2.4.1.17] | (RefSeq) UGT42A2; UDP-glycosyltransferase UGT42A2

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00830    Retinol metabolism - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0015020   GO:0016021   GO:0016758   GO:0016740   GO:0043231   GO:0008194   GO:0008152   GO:0016787   GO:0030163   GO:0015935   GO:0051603   GO:0051028   GO:0005622   GO:0006810   GO:0003824  

Subcellular location

Membrane  

SignalP

Position:   1 - 23,         Likelihood:  0.939162

 

 

Length:

509

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

25.2604

Exp number, first 60 AAs:

2.06778

Total prob of N-in:

0.09183

outside

1  -  476

TMhelix

477  -  499

inside

500  -  509

 

 

Pi

275.695279

Theta

195.381036

Tajima's D

1.495939

CLR

0.197992

CSRT

0.783860806959652

Interpretation

Uncertain