Gene

KWMTBOMO10966  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008507

Annotation

mitochondrial_import_inner_membrane_translocase_subunit_Tim9A_[Bombyx_mori]

Location

Bomo_Chr18(+):8303057-8304468      View in EpiBrowser

Full name

Mitochondrial import inner membrane translocase subunit Tim9      

Location in the cell

Cytoplasmic   Reliability : 1.123 Extracellular   Reliability : 1.577 Nuclear   Reliability : 1.444

CDS

ATGGCGACCCCTGAAATGATGAGTGAAGTTGATCAAATTAAAACTTTCAAGGATTTCCTTGTACAATACAACAAGCTGTCTGAACTTTGTTTCAATGATTGCATTCATGATTTTACGTCGAGGACTTTAAAATCTACCGAGGACAAATGCACTGTCAACTGTATGGAGAAATATCTACGAATGAATCAGAGGGTTTCACAAAGATTCCATGAGTTCCAAATGCTTGCCAATGAAAACATGTTAGCATTAGCACAAAAATCTGGTAACCCTAGTTAA

Protein

MATPEMMSEVDQIKTFKDFLVQYNKLSELCFNDCIHDFTSRTLKSTEDKCTVNCMEKYLRMNQRVSQRFHEFQMLANENMLALAQKSGNPS

Description

Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).

Subunit

Heterohexamer; composed of 3 copies of Tim9 and 3 copies of Tim10, named soluble 70 kDa complex. The complex associates with the Tim22 component of the TIM22 complex. Interacts with multi-pass transmembrane proteins in transit (By similarity).

Similarity

Belongs to the small Tim family.

Keywords

Chaperone   Complete proteome   Disulfide bond   Membrane   Metal-binding   Mitochondrion   Mitochondrion inner membrane   Protein transport   Reference proteome   Translocation   Transport   Zinc  

Feature

chain  Mitochondrial import inner membrane translocase subunit Tim9

Uniprot

Q1HQ37   A0A0L7LQT2   A0A194RV37   A0A194PGU0   A0A3S2TI84   A0A2A4JYW1   + More
A0A212EWG6   A0A2H1VZH6   H9JG60   A0A0M4EVE4   B4Q2B1   B3NWP1   A0A0K8TNY6   A0A1W4V7X0   B4JLP9   B3MXN9   A0A0L0BRG1   B4MEI0   B4L1S4   B4IGS1   D2A0D3   A0A1I8MNV7   A0A1I8Q436   B4R4C1   X2JEU5   Q9VYD7   A0A3B0K5B6   A0A1J1IB76   A0A1B0D8V3   A0A2R5LE88   A0A1B0ANA2   A0A1A9ZIA6   E2C356   Q7QE81   A0A182I9L0   A0A182PM78   A0A1A9XH46   T1DU80   E0VM34   A0A2M3ZIY7   A0A2M4AS49   W5J825   A0A182FRL1   A0A182KFQ1   A0A2M4C4U0   A0A2P6KR19   A0A0P4VNJ0   R4FJR0   A0A087U9H9   A0A182RJ33   A0A182VVC8   A0A182XY51   A0A182URN0   A0A1L8E114   A0A182X5C7   B4NEH4   A0A182N0D1   A0A1W4XM17   A0A195F992   B5DIU5   B4G7R1   D6QYC4   A0A182QS37   B4H2W4   G3MQU9   A0A182LIK4   A0A2R7WK63   A0A0C9RRK7   A0A1E1WZ18   A0A023FVX8   A0A023FFZ5   A0A195BYD8   A0A0P5TQ71   A0A0N8BWM7   A0A151IR04   B7PDS2   B0XGR7   A0A151JM11   A0A2R7VRX3   A0A1V9XW16   B7QBV2   A0A0K8R660   A0A1Q3F993   N6TWT6   E1ZWB8   E9GYJ3   F4WX31   A0A151WMY7   T1H778   A0A0N7ZPC9   A0A1B6DMF3   A0A0P4ZBJ4   A0A131XPK3   A0A154NZL8   N6TLJ8   A0A067RT82   A0A0P5V377   D6QYC2   A0A232FBV4   K7IPB3  

Pubmed

26227816    26354079    22118469    19121390    17994087    17550304    + More
26369729    26108605    18362917    19820115    25315136    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    20798317    12364791    14747013    17210077    20566863    20920257    23761445    27129103    25244985    15632085    20351054    22216098    20966253    26131772    28503490    28327890    23537049    21292972    21719571    28049606    24845553    28648823    20075255   

EMBL

DQ443215    ABF51304.1    JTDY01000310    KOB77759.1    KQ459765    KPJ20031.1    + More
KQ459604    KPI92517.1    RSAL01000119    RVE46730.1    NWSH01000347    PCG77211.1    AGBW02012000    AGBW02009830    OWR45819.1    OWR49796.1    ODYU01005418    SOQ46239.1    BABH01002044    CP012528    ALC49926.1    CM000162    EDX01572.1    CH954180    EDV47203.1    GDAI01001747    JAI15856.1    CH916371    EDV91660.1    CH902630    EDV38504.1    JRES01001467    KNC22665.1    CH940664    EDW62955.1    CH933810    EDW06727.1    CH480836    EDW49021.1    KQ971338    EFA02499.1    CM000366    EDX17823.1    AE014298    KX531321    AHN59678.1    ANY27131.1    BT025812    OUUW01000003    SPP78658.1    CVRI01000044    CRK96812.1    AJVK01004114    GGLE01003705    MBY07831.1    JXJN01000772    GL452292    EFN77588.1    AAAB01008847    EAA06794.4    APCN01000999    GAMD01000389    JAB01202.1    DS235286    EEB14440.1    GGFM01007786    MBW28537.1    GGFK01010241    MBW43562.1    ADMH02002105    ETN59010.1    GGFJ01011173    MBW60314.1    MWRG01006682    PRD28775.1    GDKW01002673    JAI53922.1    ACPB03006777    GAHY01002173    JAA75337.1    KK118852    KFM74018.1    GFDF01001666    JAV12418.1    CH964239    EDW82143.1    KQ981727    KYN37008.1    CH379060    EDY70238.1    CH479180    EDW29332.1    HM017571    HM017572    HM017573    HM017574    HM017575    HM017576    HM017577    HM017578    HM017579    HM017580    HM017581    HM017582    ADG64944.1    ADG64945.1    ADG64946.1    ADG64947.1    ADG64948.1    ADG64949.1    ADG64950.1    ADG64951.1    ADG64952.1    ADG64953.1    ADG64954.1    ADG64955.1    AXCN02002175    CH479204    EDW30681.1    JO844250    AEO35867.1    KK854960    PTY19958.1    GBZX01002879    JAG89861.1    GFAC01007162    JAT92026.1    GBBL01002412    JAC24908.1    GBBK01004467    JAC20015.1    KQ976396    KYM92951.1    GDIP01128504    GDIQ01087219    LRGB01001763    JAL75210.1    JAN07518.1    KZS10673.1    GDIQ01137643    JAL14083.1    KQ976759    KYN08551.1    ABJB011105252    DS691488    EEC04744.1    DS233058    EDS27790.1    KQ978960    KYN26928.1    KK854033    PTY09898.1    MNPL01003396    OQR77548.1    ABJB010633092    DS903634    EEC16324.1    GADI01007440    JAA66368.1    GFDL01010956    JAV24089.1    APGK01057945    KB741283    KB631738    ENN70772.1    ERL85678.1    GL434791    EFN74522.1    GL732575    EFX75474.1    GL888417    EGI61274.1    KQ982934    KYQ49203.1    GDIP01225705    JAI97696.1    GEDC01010498    JAS26800.1    GDIP01228055    JAI95346.1    GEFH01000436    JAP68145.1    KQ434786    KZC05115.1    APGK01031540    KB740814    ENN78863.1    KK852478    KDR23029.1    GDIP01106210    JAL97504.1    HM017569    HM017570    ADG64942.1    ADG64943.1    NNAY01000447    OXU28316.1   

Proteomes

UP000037510    UP000053240    UP000053268    UP000283053    UP000218220    UP000007151    + More
UP000005204    UP000092553    UP000002282    UP000008711    UP000192221    UP000001070    UP000007801    UP000037069    UP000008792    UP000009192    UP000001292    UP000007266    UP000095301    UP000095300    UP000000304    UP000000803    UP000268350    UP000183832    UP000092462    UP000092460    UP000092445    UP000008237    UP000007062    UP000075840    UP000075885    UP000092443    UP000009046    UP000000673    UP000069272    UP000075881    UP000015103    UP000054359    UP000075900    UP000075920    UP000076408    UP000075903    UP000076407    UP000007798    UP000075884    UP000192223    UP000078541    UP000001819    UP000008744    UP000075886    UP000075882    UP000078540    UP000076858    UP000078542    UP000001555    UP000002320    UP000078492    UP000192247    UP000019118    UP000030742    UP000000311    UP000000305    UP000007755    UP000075809    UP000015102    UP000076502    UP000027135    UP000215335    UP000002358   

PRIDE

Q1HQ37    H9JG60    X2JEU5    Q9VYD7   

Pfam

PF02953   zf-Tim10_DDP

Interpro

IPR004217   Tim10-like        + More
IPR035427   Tim10-like_dom_sf       
IPR039094   TIM9       

SUPFAM

SSF144122   SSF144122       

Gene 3D

1.10.287.810    

ProteinModelPortal

Q1HQ37   A0A0L7LQT2   A0A194RV37   A0A194PGU0   A0A3S2TI84   A0A2A4JYW1   + More
A0A212EWG6   A0A2H1VZH6   H9JG60   A0A0M4EVE4   B4Q2B1   B3NWP1   A0A0K8TNY6   A0A1W4V7X0   B4JLP9   B3MXN9   A0A0L0BRG1   B4MEI0   B4L1S4   B4IGS1   D2A0D3   A0A1I8MNV7   A0A1I8Q436   B4R4C1   X2JEU5   Q9VYD7   A0A3B0K5B6   A0A1J1IB76   A0A1B0D8V3   A0A2R5LE88   A0A1B0ANA2   A0A1A9ZIA6   E2C356   Q7QE81   A0A182I9L0   A0A182PM78   A0A1A9XH46   T1DU80   E0VM34   A0A2M3ZIY7   A0A2M4AS49   W5J825   A0A182FRL1   A0A182KFQ1   A0A2M4C4U0   A0A2P6KR19   A0A0P4VNJ0   R4FJR0   A0A087U9H9   A0A182RJ33   A0A182VVC8   A0A182XY51   A0A182URN0   A0A1L8E114   A0A182X5C7   B4NEH4   A0A182N0D1   A0A1W4XM17   A0A195F992   B5DIU5   B4G7R1   D6QYC4   A0A182QS37   B4H2W4   G3MQU9   A0A182LIK4   A0A2R7WK63   A0A0C9RRK7   A0A1E1WZ18   A0A023FVX8   A0A023FFZ5   A0A195BYD8   A0A0P5TQ71   A0A0N8BWM7   A0A151IR04   B7PDS2   B0XGR7   A0A151JM11   A0A2R7VRX3   A0A1V9XW16   B7QBV2   A0A0K8R660   A0A1Q3F993   N6TWT6   E1ZWB8   E9GYJ3   F4WX31   A0A151WMY7   T1H778   A0A0N7ZPC9   A0A1B6DMF3   A0A0P4ZBJ4   A0A131XPK3   A0A154NZL8   N6TLJ8   A0A067RT82   A0A0P5V377   D6QYC2   A0A232FBV4   K7IPB3  

PDB

2BSK     E-value=6.0884e-17,     Score=207

KEGG

733107    K17777 mitochondrial import inner membrane translocase subunit TIM9 | (RefSeq) mitochondrial import

GO

GO:0015031   GO:0005739   GO:0046872   GO:0008566   GO:0005744   GO:0015450   GO:0006626   GO:0016021  

PANTHER

PTHR13172:SF5  

Subcellular location

Mitochondrion inner membrane  

Length:

91

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00017

Exp number, first 60 AAs:

0

Total prob of N-in:

0.18343

outside

1  -  91

 

 

Pi

268.583549

Theta

188.718962

Tajima's D

1.333877

CLR

0

CSRT

0.744862756862157

Interpretation

Uncertain