Gene

KWMTBOMO10965  Validated by peptides from experiments

Annotation

26S_protease_regulatory_subunit_6B_[Bombyx_mori]

Location

Bomo_Chr18(-):8295958-8302876      View in EpiBrowser

Full name

26S proteasome regulatory subunit 6B      

Alternative Name

ATPase MS73

Location in the cell

Cytoplasmic   Reliability : 3.634

CDS

ATGGAAGAGATTGGAATTATTTTACCCGAGAAAGATGACCAAGTCACAGACTCAAAAGGCTTGGCGTTTGCTGGTCCTCAATCTTTTGATGAACTCGAATCTGAAGATTTATACACAAAGTACAAGAAACTCCAAAGAATGTTAGAGTTCTTAGAAGTACAAGAAGAGTACATTAAAGATGAACAACGAAACTTGAAGAAAGAATATTTGCATGCACAGGAAGAAGTAAAGCGCATACAGTCTGTTCCTCTTGTCATTGGACAGTTTCTTGAGGCAGTTGATCAAAATACAGGCATAGTTGGCAGCACCACTGGCTCAAATTATTATGTCCGTATTCTCTCAACAATTGATAGAGAATTGTTGAAGCCATCTGCTTCAGTTGCTCTGCATAAGCATTCTAATGCTCTAGTTGACGTCTTGCCTCCTGAAGCCGACAGCTCAATCTCTATGTTGCAAGCTGATGAGAAACCTGATGTTCAATATTCGGATATTGGAGGCATGGATACACAAAAACAAGAAATTAGAGAAGCTGTTGAACTCCCTCTCACTCATGTAGAGTTGTACCGGCAAATCGGTATTGAGCCTCCTCGGGGTGTGCTCATGTATGGACCACCAGGTTGTGGCAAAACTATGCTGGCTAAAGCTGTTGCGCATCACACTACAGCTGCATTCATTCGTGTCGTCGGATCAGAGTTTGTACAGAAGTACTTAGGAGAAGGACCCCGTATGGTGCGGGACGTTTTCCGTCTTGCCAAAGAGAACAGCCCAGCAATCATTTTCATTGATGAAATTGATGCCATTGCTACTAAAAGATTTGATGCCCAAACTGGTGCTGACAGAGAAGTTCAAAGGATTTTACTTGAACTCCTCAATCAAATGGATGGTTTTGATCAAACTACTAATGTTAAAGTAATAATGGCGACAAATCGTGCTGATACATTGGACCCTGCGTTGCTAAGACCTGGCCGTCTCGACAGAAAAATCGAGTTTCCACTTCCAGATAGGCGTCAAAAACGTTTGATTTTCTCGACAATCACTACCAAGATGAACCTTTCGGATGAAGTGGATTTGGAAGAGTTCGTGGCTCGACCGGACCGCGTGTCCGGCGCCGACATCAACGCCATCTGTCAGGAGGCCGGCATGCACGCTGTCAGGGAAAACAGATATATTGTCCTTCCTAAAGATTTCGAAAAGGGTTACAAGAATAACATCAAGAAAGATGAGAGCGAATATGAATTTTATAAATAA

Protein

MEEIGIILPEKDDQVTDSKGLAFAGPQSFDELESEDLYTKYKKLQRMLEFLEVQEEYIKDEQRNLKKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKHSNALVDVLPPEADSSISMLQADEKPDVQYSDIGGMDTQKQEIREAVELPLTHVELYRQIGIEPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENSPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITTKMNLSDEVDLEEFVARPDRVSGADINAICQEAGMHAVRENRYIVLPKDFEKGYKNNIKKDESEYEFYK

Similarity

Belongs to the AAA ATPase family.
Belongs to the chaperonin (HSP60) family.

Keywords

ATP-binding   Cytoplasm   Nucleotide-binding   Nucleus   Proteasome  

Feature

chain  26S proteasome regulatory subunit 6B

Uniprot

Q1HQC6   A0A194RRE2   A0A194PHK2   S4PMY9   A0A3S2NG70   A0A212ERW1   + More
A0A2A4K0B5   P46507   A0A0L7LQQ2   A0A023F9E3   A0A069DTK3   A0A224XHA4   A0A0V0G462   A0A0P4VYP8   T1HWM8   A0A0J7K4C5   A0A151IL40   A0A067R5X0   A0A232EWM5   A0A151I1N8   R4WQ99   A0A158NWF7   A0A146L2K7   A0A026W6D7   A0A2J7PY89   V5H489   R4G4S4   A0A0B4J2S6   A0A2A3E4P2   A0A0B4J2L4   E0VLH1   A0A2D1QUF4   A0A1B6I5B8   A0A1B6MST4   U4UE03   D2A3L0   J3JXC5   A0A1Y1MG72   U5EX58   A0A1W4XP02   A0A182JBW4   A0A2H8TIM3   J9K231   A0A2S2NCY1   A0A0C9R7B3   A0A2S2QFB9   A0A1B0D005   A0A1B0CWD5   A0A084VRA2   A0A182FRE1   Q172T1   A0A0K8TS19   A0A023ES58   T1DQ58   A0A087UUW8   A0A2M3ZH78   A0A2M4ACC4   A0A2M4BPU6   W5J2K0   A0A336MP05   A0A336M3B9   A0A1L8DSZ5   B4IDY0   A0A2M4BPP1   A0A293MNK9   A0A2L2XXR0   A0A182N646   A0A182QUD8   A0A182PKL3   A0A182UV46   A0A1W4UNG1   A0A2R5LJL4   F4X2X2   A0A182LFV1   A0A182MVR2   A0A182TM97   A0A182WRK4   Q7PGR3   A0A182HU72   Q29IU3   B4HAN5   A0A182RNR9   B4PYF6   A0A182KCN6   A0A182W058   Q9V405   A0A1Q3FDQ4   B0WDD3   E1UIA5   A0A182Y4A2   V4AYR7   A0A1A9YJ99   A0A3B0KVF1   A0A1A9URJ6   A0A1B0BAZ4   A0A1J1I539   I4DK60   E2AR79   A0A1A9ZQF7   A0A1A9W911  

Pubmed

26354079    23622113    22118469    7829521    26227816    25474469    + More
26334808    27129103    24845553    28648823    23691247    21347285    26823975    24508170    30249741    20075255    20566863    23537049    18362917    19820115    22516182    28004739    24438588    17510324    26369729    24945155    20920257    23761445    17994087    26561354    21719571    20966253    12364791    14747013    17210077    15632085    17550304    10893261    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    20150340    26109357    26109356    25244985    23254933    22651552    20798317   

EMBL

DQ443126    ABF51215.1    KQ459765    KPJ20042.1    KQ459604    KPI92528.1    + More
GAIX01003285    JAA89275.1    RSAL01000119    RVE46740.1    AGBW02012905    OWR44233.1    NWSH01000347    PCG77213.1    Z38135    JTDY01000310    KOB77760.1    GBBI01000595    JAC18117.1    GBGD01001624    JAC87265.1    GFTR01006012    JAW10414.1    GECL01003272    JAP02852.1    GDKW01000855    JAI55740.1    ACPB03018669    LBMM01014446    KMQ85177.1    KQ977133    KYN05473.1    KK852673    KDR18744.1    NNAY01001839    OXU22752.1    KQ976573    KYM80378.1    AK417871    BAN21086.1    ADTU01027934    ADTU01027935    GDHC01017197    JAQ01432.1    KK107373    QOIP01000004    EZA51657.1    RLU23417.1    NEVH01020850    PNF21313.1    GALX01000848    JAB67618.1    GAHY01000521    JAA76989.1    KZ288375    PBC26697.1    DS235271    EEB14227.1    KY285060    ATP16163.1    GECU01025577    JAS82129.1    GEBQ01000983    JAT38994.1    KB632031    ERL88150.1    KQ971338    EFA02331.1    BT127894    AEE62856.1    GEZM01034735    GEZM01034732    JAV83640.1    GANO01001114    JAB58757.1    GFXV01002161    MBW13966.1    ABLF02040066    GGMR01002376    MBY14995.1    GBYB01003850    JAG73617.1    GGMS01007232    MBY76435.1    AJVK01009796    AJWK01032248    ATLV01015566    KE525023    KFB40496.1    CH477432    EAT41016.1    GDAI01000456    JAI17147.1    GAPW01001541    JAC12057.1    GAMD01002739    JAA98851.1    KK121764    KFM81157.1    GGFM01007108    MBW27859.1    GGFK01005112    MBW38433.1    GGFJ01005842    MBW54983.1    ADMH02002131    GGFL01004375    ETN58492.1    MBW68553.1    UFQT01001638    SSX31271.1    UFQS01000344    UFQT01000344    SSX03057.1    SSX23423.1    GFDF01004553    JAV09531.1    CH480830    EDW45788.1    GGFJ01005843    MBW54984.1    GFWV01022560    MAA47287.1    IAAA01008730    LAA00718.1    AXCN02000196    GGLE01005565    MBY09691.1    GL888600    EGI59193.1    AXCM01000845    AAAB01008859    EAA44836.4    EGK96659.1    APCN01000610    CH379063    EAL32560.1    CH479242    EDW37646.1    CM000162    EDX02018.1    AF145306    AE014298    BT046144    FN544098    FN544099    FN544100    FN544101    FN544102    FN544103    FN544104    FN544105    FN544106    FN544108    AAF08387.1    AAF48001.1    ACI46532.1    AHN59578.1    CBA35179.1    CBA35180.1    CBA35181.1    CBA35182.1    CBA35183.1    CBA35184.1    CBA35185.1    CBA35186.1    CBA35187.1    CBA35189.1    GFDL01009349    JAV25696.1    DS231896    EDS44446.1    FN544107    CBA35188.1    KB200129    ESP02818.1    OUUW01000035    SPP89836.1    JXJN01011228    CVRI01000041    CRK95405.1    AK401678    BAM18300.1    GL441909    EFN64061.1   

Proteomes

UP000053240    UP000053268    UP000283053    UP000007151    UP000218220    UP000037510    + More
UP000015103    UP000036403    UP000078542    UP000027135    UP000215335    UP000078540    UP000005205    UP000053097    UP000279307    UP000235965    UP000002358    UP000242457    UP000005203    UP000009046    UP000030742    UP000007266    UP000192223    UP000075880    UP000007819    UP000092462    UP000092461    UP000030765    UP000069272    UP000008820    UP000054359    UP000000673    UP000001292    UP000075884    UP000075886    UP000075885    UP000075903    UP000192221    UP000007755    UP000075882    UP000075883    UP000075902    UP000076407    UP000007062    UP000075840    UP000001819    UP000008744    UP000075900    UP000002282    UP000075881    UP000075920    UP000000803    UP000002320    UP000076408    UP000030746    UP000092443    UP000268350    UP000078200    UP000092460    UP000183832    UP000000311    UP000092445    UP000091820   

PRIDE

Q1HQC6    P46507    Q9V405    E1UIA5   

Pfam

PF17862   AAA_lid_3        + More
PF16450   Prot_ATP_ID_OB
PF00004   AAA
PF00118   Cpn60_TCP1

Interpro

IPR027417   P-loop_NTPase        + More
IPR003960   ATPase_AAA_CS       
IPR035256   PSMC4       
IPR001270   ClpA/B       
IPR003959   ATPase_AAA_core       
IPR005937   26S_Psome_P45-like       
IPR032501   Prot_ATP_ID_OB       
IPR003593   AAA+_ATPase       
IPR041569   AAA_lid_3       
IPR027413   GROEL-like_equatorial_sf       
IPR027409   GroEL-like_apical_dom_sf       
IPR027410   TCP-1-like_intermed_sf       
IPR002423   Cpn60/TCP-1       
IPR018370   Chaperonin_Cpn60_CS       
IPR001844   Chaprnin_Cpn60       

SUPFAM

SSF52540   SSF52540        + More
SSF52029   SSF52029       
SSF48592   SSF48592       

Gene 3D

1.10.560.10     3.30.260.10     3.50.7.10    

CDD

cd03344  GroEL

ProteinModelPortal

Q1HQC6   A0A194RRE2   A0A194PHK2   S4PMY9   A0A3S2NG70   A0A212ERW1   + More
A0A2A4K0B5   P46507   A0A0L7LQQ2   A0A023F9E3   A0A069DTK3   A0A224XHA4   A0A0V0G462   A0A0P4VYP8   T1HWM8   A0A0J7K4C5   A0A151IL40   A0A067R5X0   A0A232EWM5   A0A151I1N8   R4WQ99   A0A158NWF7   A0A146L2K7   A0A026W6D7   A0A2J7PY89   V5H489   R4G4S4   A0A0B4J2S6   A0A2A3E4P2   A0A0B4J2L4   E0VLH1   A0A2D1QUF4   A0A1B6I5B8   A0A1B6MST4   U4UE03   D2A3L0   J3JXC5   A0A1Y1MG72   U5EX58   A0A1W4XP02   A0A182JBW4   A0A2H8TIM3   J9K231   A0A2S2NCY1   A0A0C9R7B3   A0A2S2QFB9   A0A1B0D005   A0A1B0CWD5   A0A084VRA2   A0A182FRE1   Q172T1   A0A0K8TS19   A0A023ES58   T1DQ58   A0A087UUW8   A0A2M3ZH78   A0A2M4ACC4   A0A2M4BPU6   W5J2K0   A0A336MP05   A0A336M3B9   A0A1L8DSZ5   B4IDY0   A0A2M4BPP1   A0A293MNK9   A0A2L2XXR0   A0A182N646   A0A182QUD8   A0A182PKL3   A0A182UV46   A0A1W4UNG1   A0A2R5LJL4   F4X2X2   A0A182LFV1   A0A182MVR2   A0A182TM97   A0A182WRK4   Q7PGR3   A0A182HU72   Q29IU3   B4HAN5   A0A182RNR9   B4PYF6   A0A182KCN6   A0A182W058   Q9V405   A0A1Q3FDQ4   B0WDD3   E1UIA5   A0A182Y4A2   V4AYR7   A0A1A9YJ99   A0A3B0KVF1   A0A1A9URJ6   A0A1B0BAZ4   A0A1J1I539   I4DK60   E2AR79   A0A1A9ZQF7   A0A1A9W911  

PDB

6MSK     E-value=0,     Score=1696

KEGG

732870    K03063 26S proteasome regulatory subunit T3 | (RefSeq) 26S protease regulatory subunit 6B

PATHWAY

03050    Proteasome - Bombyx mori (domestic silkworm)

GO

GO:0036402   GO:0030163   GO:0008233   GO:0005737   GO:0005524   GO:0005634   GO:0000502   GO:0008568   GO:0045202   GO:0008540   GO:0045899   GO:0031597   GO:0042026   GO:0001673   GO:0043161   GO:0016887   GO:0007623   GO:0005829   GO:0008063   GO:0005654   GO:0005838   GO:0016787   GO:0015935   GO:0051603   GO:0051028   GO:0005622   GO:0006810   GO:0003824  

PANTHER

PTHR23073:SF8  

Subcellular location

Cytoplasm  
Nucleus  

Length:

415

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00093

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00099

outside

1  -  415

 

 

Pi

305.069213

Theta

174.419893

Tajima's D

2.40406

CLR

0.109202

CSRT

0.935903204839758

Interpretation

Uncertain