SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO10936  Validated by peptides from experiments
Annotation
hypothetical_protein_KGM_19166_[Danaus_plexippus]
Full name
Proteasome subunit beta      
Location in the cell
Extracellular   Reliability : 1.091
 

Sequence

CDS
ATGTCAAATATAAACTTACAATGTCTCTTAGGAATACAGTGCAACGACTTTGTTATGATAGCAGCCGATCAGAGCAACAGCCACAGCATTATGATCATGAAAGACGATGAAGAAAAGATCTATAAGATATCTGATAGATTAGTAATGGGTGTCATTGGTGACTCAGGAGACACAAATCAATTTGCTGAATATATTGCAAAAAATATTCAGTTGTATAAAATGCGTAATGGGTATGAATTGGGGCCCTCAGCTGCAGCCAGTTTCACACGTCGTAATCTCGCAGAGTATCTTAGGAGCAGTACTCCCTACTTTGTAAATGTGCTCATGGGTGGTTATGATAAAGAAAATGGACCTGAACTGTATTTTATGGACTATTTAGCATCAAGCGTGAAGGTACCATTTGCAGCTCATGGTTATGGTGGATATCTAAGTTTGAGTATTATGGATCGTTACCATAAAAAAGATGCTACAGAAACAGAGGCATATGACATCCTTAAGAAGTGTGTTCAAGAAGTTCACAAAAGATTGTTTGTTAGTCTCCCCAATTTCCAAGTGACTGTTGTAAACCGTGATGGGATTAAAGTGCTGCCCACCATTAATTCTGCATCTCTTCAATAA
Protein
MSNINLQCLLGIQCNDFVMIAADQSNSHSIMIMKDDEEKIYKISDRLVMGVIGDSGDTNQFAEYIAKNIQLYKMRNGYELGPSAAASFTRRNLAEYLRSSTPYFVNVLMGGYDKENGPELYFMDYLASSVKVPFAAHGYGGYLSLSIMDRYHKKDATETEAYDILKKCVQEVHKRLFVSLPNFQVTVVNRDGIKVLPTINSASLQ

Summary

Catalytic Activity
Cleavage of peptide bonds with very broad specificity.
Subunit
The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.
Similarity
Belongs to the peptidase T1B family.
Feature
chain  Proteasome subunit beta
EC Number
3.4.25.1
EMBL
RSAL01001425    RSAL01000123    RVE40795.1    RVE46634.1    KQ459765    KPJ20072.1    + More
KQ459604    KPI92554.1    GAIX01005932    JAA86628.1    KZ149920    PZC77769.1    NWSH01000165    PCG78887.1    ODYU01002848    SOQ40839.1    GDQN01001803    JAT89251.1    AGBW02009208    OWR51367.1    NEVH01025130    PNF15952.1    KQ434978    KZC12964.1    GL451420    EFN79330.1    AK403258    BAM19664.1    KZ288215    PBC32532.1    KQ414727    KOC62491.1    KK852779    KDR16684.1    KK107020    QOIP01000006    EZA62569.1    RLU21138.1    GDIP01061421    JAM42294.1    GDIP01081769    JAM21946.1    GDIQ01184930    GDIQ01180584    GDIQ01046076    JAK66795.1    GDIQ01121404    JAL30322.1    GDIQ01112850    JAL38876.1    GDIP01002599    LRGB01003216    JAN01117.1    KZS03717.1    GDIP01205751    JAJ17651.1    GDIQ01107355    JAL44371.1    NNAY01003382    OXU19505.1    AAZX01001624    KQ977033    KYN06198.1    GDIQ01019830    JAN74907.1    GDIP01059470    JAM44245.1    GL762106    EFZ22229.1    KQ982129    KYQ59858.1    GL888679    EGI58555.1    KQ976730    KYM76394.1    KQ981993    KYN31130.1    ADTU01027584    KQ769068    OAD52975.1    GDIQ01151547    JAL00179.1    GDIQ01231915    JAK19810.1    GL732633    EFX69663.1    GDIQ01139143    JAL12583.1    GDIQ01141148    JAL10578.1    KQ435821    KOX72411.1    GEZM01000453    GEZM01000452    JAV98413.1    GDIP01055077    JAM48638.1    GDIP01127812    JAL75902.1    GDIQ01136649    JAL15077.1    EF179416    ABM55422.1    KQ971354    EFA06200.1    KC989882    KC989883    AGN29655.1    GFWV01022540    MAA47267.1    KY314165    AQS22599.1    GALX01002473    JAB65993.1    DS235818    EEB17681.1    ODYU01000215    SOQ34614.1    APGK01054913    BT126798    KB741253    KB632340    AEE61760.1    ENN71815.1    ERL92957.1    GGLE01003714    MBY07840.1    GFJQ02001134    JAW05836.1    GDIP01121413    JAL82301.1    DS231821    EDS45003.1    GANO01002000    JAB57871.1    GFDL01009406    JAV25639.1    GBHO01021652    GDHC01019431    JAG21952.1    JAP99197.1    GFPF01005504    MAA16650.1    GFPF01005505    MAA16651.1    GBBL01001959    JAC25361.1    JXUM01108243    GAPW01004449    KQ565213    JAC09149.1    KXJ71212.1    CH477240    EAT46434.1    GDAI01000480    JAI17123.1    GEDC01003147    JAS34151.1    GEDV01006152    JAP82405.1    GBRD01016548    JAG49278.1    KZ150214    PZC72143.1    UFQS01000002    UFQT01000002    SSW96721.1    SSX17108.1    GFAC01004698    JAT94490.1    JXUM01015684    JXUM01015685    KQ560437    KXJ82419.1    JH815987    EKC21877.1    RSAL01000095    RVE47821.1    AMQN01012817    KB309774    ELT93338.1    GDIQ01149196    JAL02530.1    AAAB01008984    EAA14834.3    GAPW01004450    JAC09148.1    NWSH01000405    PCG76649.1    BC072908    BC106262    CM004468    AAH72908.1    AAI06263.1    OCT94763.1    GADI01006476    JAA67332.1    ATLV01018364    KE525231    KFB43001.1   
Pfam
PF00227   Proteasome
Interpro
IPR029055   Ntn_hydrolases_N        + More
IPR016050   Proteasome_bsu_CS       
IPR001353   Proteasome_sua/b       
IPR023333   Proteasome_suB-type       
IPR035206   Proteasome_beta2       
SUPFAM
SSF56235   SSF56235       
Gene 3D
PDB
3UNH     E-value=9.99321e-57,     Score=553

Ontologies

Topology

Subcellular location
Cytoplasm  
Nucleus  
Length:
205
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.44315
Exp number, first 60 AAs:
0.00324
Total prob of N-in:
0.04112
outside
1  -  205
 
 

Population Genetic Test Statistics

Pi
127.048439
Theta
142.613292
Tajima's D
-0.417432
CLR
11.458177
CSRT
0.260236988150592
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
31250652 SKVKMSLLPFILGYQPNRLRDQDFGLALTPDDLLTAVITPTMSRDYYRPWKQMAMANRDVGSTITSNKDKFQVNLDVQHFSPEEISVKTADGYVIVEGKHEERQDEHGYISRQFTRRYALPENCNPDTVESRLSSDGVLTVIAPRTPAATKNERAVPITQTGPVRKEIKEPTAEVESNETKQ 100.00 2e-35
31250652 IVLIDDQSSPIPSGTIR 100.00 2e-08
28556443 VLPTINSASLQ 100.00 2e-08
26822097 FIPTIVIDGVFDQATQNK 95.24 4e-08
26280517 IVMDKETDKFK 95.24 4e-08
28467696 IVMDKETDKFK 95.24 4e-08
31250652 ENGPELYFMDYLASSVK 100.00 8e-08
31250652 DAEQALHLANK 100.00 7e-06
28556443 NGYELGPSAAASFTR 100.00 3e-05
28556443 MDLIGGLVR 100.00 1e-04
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