Gene

KWMTBOMO10928

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr18(+):7386813-7388971      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS       + More
Probable RNA-directed DNA polymerase from transposon X-element      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 2.12

CDS

ATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCCAACCGCGTTATTAAACTTTTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCAAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCAGACGTTATCGGCATACATAAACAGGGTAAACCAAAAAATCATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTCATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGGTATCGAGTCGAGGGAACCCGCTCCTCCCCACGATCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTTAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCCAGTAGAAACAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATTAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCTTTACAATCCCGCTTTTGCAGGTTAGCCGTCGGAGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCTATCCAGAAATACATGAAGTCAGTGTCGGAACGGTACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTAGCCGCCGCTGACTACTCCCCGAATCCTGATCACGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTTGCATTAGACGCCTTCAGCTCTAACACTAGGAGCAGGCTTAGGGACCTCGGTAACCGTACTCGTCGAACTCGACAAAGAGTTCGCCGTGCAACCTAA

Protein

MEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKQGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRSLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFRQPIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIQKYMKSVSERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSSNTRSRLRDLGNRTRRTRQRVRRAT

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9XXW0   Q9BPQ0   K9N5J5   A0A0N0PA09   A0A0N1PFV1   + More
O96546   O96544   A0A194Q1H8   A0A1Y1NA23   V5GNF3   A0A2S2PR14   A0A139WA11   V5GNJ2   X1WMU5   A0A139W8G9   X1WXU3   X1WLB2   J9KKL3   X1WWC4   A0A2S2PH29   A0A087U2S8   V5I850   A0A2S2QTZ8   A0A2S2Q823   A0A2S2PX53   A0A1Y1M7E9   J9KC83   A0A2S2PPK8   A0A023EYS8   A0A023EZE6   A0A224XF24   A0A2S2QJM7   A0A2S2N814   A0A087T1W0   A0A2S2QEE0   O76197   A0A2S2NGV8   A0A2H8TES1   A0A2S2RAN7   J9LC15   A0A2S2Q352   A0A2J7R7D0   A0A2J7RL12   J9M522   A0A2M4BDV6   A0A1Y1LKN6   A0A2J7RS81   A0A2A4K8E7   A0A2H8TWD9   A0A2J7PVX3   A0A2M4BD67   A0A2J7PEB1   A0A2H8U0H5   A0A0J7K4E0   A0A3N5Z7I3   A0A087V0P8   A0A2S2NJB5   A0A2J7QPI2   A0A2J7Q627   A0A2J7R579   A0A2J7R4B1   Q07995   J9KCZ4   X1WZH0   A0A0A9YJ00   Q95SX7   A0A069DZC5   A0A182GB02   A0A2S2R9D4   A0A2J7R8R8   A0A069DW01   A0A2J7RIW7   A0A2J7Q059   A0A2J7R4B7   A0A2J7Q4F7   A0A2J7RM10   X1WN18   A0A2J7QUJ9   A0A2J7PMP6   A0A2J7RB54   A0A2A4K918   A0A2J7PDM0   A0A2J7RPU2   Q9NBX4   A0A023F6S4   A0A146LCK7   A0A2J7PU96   A0A182GMD9   A0A1L8DIZ6   A0A2J7QB68   A0A2J7PMP9   A0A2J7PQB5   A0A2J7RS77   A0A2S2PYN7   A0A224XB44   A0A0A9YU04   A0A0J7KBP6   X1WNI2   A0A1Y1K0N4  

EC Number

2.7.7.49

Pubmed

10333566    23652563    26354079    10380107    28004739    18362917    + More
19820115    25474469    8934517    30086797    8387152    25401762    7753626    12537569    26334808    26483478    11405632    26823975   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KC165845    AFY12622.1    KQ459259    KPJ02068.1    KQ459265    KPJ02064.1    AF081103    AAC72921.1    AF081101    AAC72919.1    KQ459580    KPI99178.1    GEZM01008457    JAV94772.1    GALX01005359    JAB63107.1    GGMR01019198    MBY31817.1    KQ971729    KYB24751.1    GALX01005299    JAB63167.1    ABLF02014862    ABLF02014866    ABLF02061908    KQ973342    KXZ75569.1    ABLF02008933    ABLF02042518    ABLF02057746    ABLF02029306    ABLF02029314    ABLF02060138    ABLF02003961    ABLF02059872    GGMR01016114    MBY28733.1    KK117880    KFM71667.1    GALX01005300    JAB63166.1    GGMS01012005    MBY81208.1    GGMS01004685    MBY73888.1    GGMS01000737    MBY69940.1    GEZM01038405    JAV81653.1    ABLF02033757    GGMR01018716    MBY31335.1    GBBI01004395    JAC14317.1    GBBI01004571    JAC14141.1    GFTR01008038    JAW08388.1    GGMS01008766    MBY77969.1    GGMR01000676    MBY13295.1    KK113014    KFM59099.1    GGMS01006359    MBY75562.1    AF012049    AAC24972.1    GGMR01003407    MBY16026.1    GFXV01000774    MBW12579.1    GGMS01017914    MBY87117.1    ABLF02020655    ABLF02039168    ABLF02061060    GGMS01002955    MBY72158.1    NEVH01006736    PNF36716.1    NEVH01002704    PNF41489.1    ABLF02024246    GGFJ01001857    MBW50998.1    GEZM01053022    JAV74219.1    NEVH01000269    PNF43694.1    NWSH01000032    PCG80497.1    GFXV01006424    MBW18229.1    NEVH01020940    PNF20481.1    GGFJ01001858    MBW50999.1    NEVH01026106    PNF14658.1    GFXV01007093    MBW18898.1    LBMM01014395    KMQ85192.1    RPOV01000134    RPJ78669.1    KL813758    KFM83187.1    GGMR01004661    MBY17280.1    NEVH01012089    PNF30491.1    NEVH01017542    PNF24034.1    NEVH01007393    PNF35987.1    NEVH01007578    PNF35646.1    S59870    AAB26437.2    ABLF02008463    ABLF02034467    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    AY060438    AAL25477.1    GBGD01000880    JAC88009.1    JXUM01241784    KQ635293    KXJ62492.1    GGMS01017365    MBY86568.1    NEVH01006721    PNF37225.1    GBGD01000799    JAC88090.1    NEVH01003017    PNF40781.1    NEVH01020071    PNF21969.1    NEVH01007443    PNF35684.1    NEVH01018383    PNF23463.1    NEVH01021586    NEVH01006600    NEVH01002584    PNF19589.1    PNF37419.1    PNF41868.1    ABLF02021177    ABLF02027367    ABLF02066338    NEVH01010546    PNF32261.1    NEVH01023962    PNF17612.1    NEVH01005938    PNF38077.1    PCG80496.1    NEVH01026386    PNF14434.1    NEVH01001355    PNF42855.1    AF237761    AAF81411.1    GBBI01001646    JAC17066.1    GDHC01014349    JAQ04280.1    NEVH01021205    PNF19912.1    JXUM01014072    KQ560393    KXJ82651.1    GFDF01007661    JAV06423.1    NEVH01016302    PNF25823.1    NEVH01023961    PNF17613.1    NEVH01022639    PNF18527.1    NEVH01000280    PNF43672.1    GGMS01001277    MBY70480.1    GFTR01008262    JAW08164.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    LBMM01010106    KMQ87671.1    ABLF02008153    ABLF02008462    ABLF02008464    GEZM01097906    JAV54051.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000054359    UP000235965    UP000218220    + More
UP000036403    UP000069940    UP000249989   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    K9N5J5    Q95SX7    Q9NBX4    + More

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF03372   Exo_endo_phos
PF07530   PRE_C2HC
PF10551   MULE

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR018289   MULE_transposase_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   K9N5J5   A0A0N0PA09   A0A0N1PFV1   + More
O96546   O96544   A0A194Q1H8   A0A1Y1NA23   V5GNF3   A0A2S2PR14   A0A139WA11   V5GNJ2   X1WMU5   A0A139W8G9   X1WXU3   X1WLB2   J9KKL3   X1WWC4   A0A2S2PH29   A0A087U2S8   V5I850   A0A2S2QTZ8   A0A2S2Q823   A0A2S2PX53   A0A1Y1M7E9   J9KC83   A0A2S2PPK8   A0A023EYS8   A0A023EZE6   A0A224XF24   A0A2S2QJM7   A0A2S2N814   A0A087T1W0   A0A2S2QEE0   O76197   A0A2S2NGV8   A0A2H8TES1   A0A2S2RAN7   J9LC15   A0A2S2Q352   A0A2J7R7D0   A0A2J7RL12   J9M522   A0A2M4BDV6   A0A1Y1LKN6   A0A2J7RS81   A0A2A4K8E7   A0A2H8TWD9   A0A2J7PVX3   A0A2M4BD67   A0A2J7PEB1   A0A2H8U0H5   A0A0J7K4E0   A0A3N5Z7I3   A0A087V0P8   A0A2S2NJB5   A0A2J7QPI2   A0A2J7Q627   A0A2J7R579   A0A2J7R4B1   Q07995   J9KCZ4   X1WZH0   A0A0A9YJ00   Q95SX7   A0A069DZC5   A0A182GB02   A0A2S2R9D4   A0A2J7R8R8   A0A069DW01   A0A2J7RIW7   A0A2J7Q059   A0A2J7R4B7   A0A2J7Q4F7   A0A2J7RM10   X1WN18   A0A2J7QUJ9   A0A2J7PMP6   A0A2J7RB54   A0A2A4K918   A0A2J7PDM0   A0A2J7RPU2   Q9NBX4   A0A023F6S4   A0A146LCK7   A0A2J7PU96   A0A182GMD9   A0A1L8DIZ6   A0A2J7QB68   A0A2J7PMP9   A0A2J7PQB5   A0A2J7RS77   A0A2S2PYN7   A0A224XB44   A0A0A9YU04   A0A0J7KBP6   X1WNI2   A0A1Y1K0N4  

KEGG

101737297    no KO assigned | (RefSeq) esterase FE4-like

GO

GO:0003964   GO:0004519   GO:0016021   GO:0006313  

Length:

512

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

15.8601699999999

Exp number, first 60 AAs:

12.96285

Total prob of N-in:

0.43604

POSSIBLE N-term signal

sequence

outside

1  -  512

 

 

Pi

34.852913

Theta

20.074477

Tajima's D

0.342809

CLR

0.512892

CSRT

0.474326283685816

Interpretation

Uncertain