Gene

KWMTBOMO10911

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr18(-):6521637-6524413      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS       + More
RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.992

CDS

ATGGGAGACTCCGTCATCCTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCATCGTACTAACGTTAACGGTAGGCGTCTCGACGCGTTTATAGACGACCTCACCTTTGAAATAGTCGGTCCCCCAACTCCAACATGTTATCCGTATAACATCGCGCTCCGTCCGAGCACTATAGACCTGGCATTGCTTAGGAACGTAACTCTGCGCTTGCGTTCCATCGAAGCAATGTCAGAGCTCGACTCAGACCACCGACCTGTCGTTATGCAGCTCGGTCGCCCCCACAACCCAGTCACTGTTACGAGGACCATGGTGGATTGGAATAAGCTGGGCACGTGCCTAGCCGACACCGCTCCGCCAATCCTCACTTACGGCCCGGATTCGAATCTATCCCCCGAGGACACCGTCGAATCCGTAAACATAATTACCGATCACATCTCTTCCGCGATCATTAGATCTTCTAAAGAAGTCGATGTGGAGGACAGCTTCCACCGCATCAGACTGTCTCCCGATCTTAGGAATCTCTTAAGAGTTAGGAACGCGGCAATCCGGGCCTACGATCGTCTTCCCACGCATTCAAACCGGATTCAGATGCGTCGTCTACAACGCGAAGTCCACTCCCGCTTAAGCGACGCGCGTAACGATAATTGGCATAGTTATTTAGAACAACTCGCGCCCTCCCACCAAGCATACTGGCGACTAGCTAGGACTCTCAAATCCGAAACTACCGCTACTATGCCTCCCCTCGTACGCCCTTCAGGCCAACCACCGGCATTCGATGACGAAGACAAGGCTGAGCTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGGACCCCGAACACACCGAGTTAGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCGCCCTCGGACGCGTTACCCCCCATTACCACCGACGAAGTTAGAGACGCGATCCACAACCTACAACCTAGGAAGGCACCCGGCTCCGACGGCATCCACAACCGCGCGCTTAAACTCTTGCCAGTCCAACTGATAGCAATGTTGGCTACAATTTTAAATGCCGCTATGACGCACTGCATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGTATACATAAGCCGGGCAAACCGACAAACGAAACTTCTAGTTACCGTCCGATTAGTCTCCTCTCGACGATAGGAAAAATTTACGAACGGCTCCTTAGGAAACGCCTCTGGGATTTTGTTACCGCGAACAAAATTCTCATAGACGAACAGTTCGGATTCCGCTCAAAACACTCGTGCGTACAACAAGTGCACCGCCTCACGGAGCACATTCTGATAGGACTAAATAGGCGTAAACAAATCCCGACCGGCGCCCTCTTCTTCGACATCGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTAATTTATAAACTGTACAACATGGGAGTGCCAGACAGACTCGTGCTCATCATACGAGACTTCTTGTCGAACCGTTCGTTTCGATATCGAGTAGAGGGAACTCGTTCTCGTCCCCGTCAACTGACCGCCGGAGTCCCGCAAGGCTCCGCGCTCTCCCCGTTATTATTTAGTTTGTATATCAATGATATACCCCGGTCTCCGGAGACCCATCTAGCGCTCTTCGCCGATGACACGGCTATCTACTACTCGTGTAGGAAGATGTCGCTGCTTCATCGGCGACTCCAGATCGCAGTAGCCACCATGGGACAGTGGTTCCGGAAGTGGCGAATAGACATCAACCCCACGAAAAGCGCAGCGGTGCTCTTCAAAAGGGGTCGCCCTCCGAACATCACTTCGAGCATCCCACTCCGTAGTAGGCGCGCAAACACCTCCGCCGTTAGTCCCATCACTCTCTTTGGCCAGCCCATACCGTGGGTCTCGAAGGTCAAATATCTAGGCGTCACCCTCGACAGAGGGATGACATTCCGTCCCCATATAAAAACGGTACGCGACCGCGCCGCGTTTATTCTAGGACGACTCTATCCAATGCTTTGTAGTCGAAGCAAACTGTCCCTCCGTAATAAGGTAACTCTCTACAAAACTTGTATACGCCCCGTCATGACGTATGCAAGCGTAGTGTTCGCTCACGCAGCCCGCACCAACTTGAAATCCCTTCAGGTTATTCAATCACGATTCTGCAGGATAGCCGTCGGAGCGCCTTGGTTCCTTAGGAATGTGGATCTCCACGACGACCTGGAGCTCGACTCTTTTAGTAAGTATCTACAGTCGGCATCGCTGCGCCATTTTGAGAAGGCGGCACGACATGAGAACCCTCTCATCGTAGCCGCTGGAAATTACATACCCGACCCAGTAGACCGAATGGTAAACCGTCGACGTCGCCCAAAGCACGTCATTACGGATCCTCCTGATCCATTAACGGTGCTTTTAGGCACCACAAGCACCGGTCACCGTCCTCGTCGAACCCGTCGCTTGCGACGAAGGGCTCGACGAGCGAACTAA

Protein

MGDSVILAGDLNCHHTRWNCHRTNVNGRRLDAFIDDLTFEIVGPPTPTCYPYNIALRPSTIDLALLRNVTLRLRSIEAMSELDSDHRPVVMQLGRPHNPVTVTRTMVDWNKLGTCLADTAPPILTYGPDSNLSPEDTVESVNIITDHISSAIIRSSKEVDVEDSFHRIRLSPDLRNLLRVRNAAIRAYDRLPTHSNRIQMRRLQREVHSRLSDARNDNWHSYLEQLAPSHQAYWRLARTLKSETTATMPPLVRPSGQPPAFDDEDKAELLADALQEQCTTSTQHADPEHTELVDREVERRASLPPSDALPPITTDEVRDAIHNLQPRKAPGSDGIHNRALKLLPVQLIAMLATILNAAMTHCIFPAVWKEADVIGIHKPGKPTNETSSYRPISLLSTIGKIYERLLRKRLWDFVTANKILIDEQFGFRSKHSCVQQVHRLTEHILIGLNRRKQIPTGALFFDIAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDFLSNRSFRYRVEGTRSRPRQLTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKMSLLHRRLQIAVATMGQWFRKWRIDINPTKSAAVLFKRGRPPNITSSIPLRSRRANTSAVSPITLFGQPIPWVSKVKYLGVTLDRGMTFRPHIKTVRDRAAFILGRLYPMLCSRSKLSLRNKVTLYKTCIRPVMTYASVVFAHAARTNLKSLQVIQSRFCRIAVGAPWFLRNVDLHDDLELDSFSKYLQSASLRHFEKAARHENPLIVAAGNYIPDPVDRMVNRRRRPKHVITDPPDPLTVLLGTTSTGHRPRRTRRLRRRARRAN

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139WA11   A0A139W8G9   V5GNJ2   V5GNF3   A0A023EYS8   A0A023EZE6   X1WLB2   A0A2S2QEE0   A0A2S2PPK8   A0A3N5Z7I3   A0A224XF24   Q07995   J9KKL3   A0A2M4BEF4   A0A2M4BEZ9   A0A2S2Q383   J9LC21   A0A2S2PR14   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   J9M522   A0A224X6Q4   A0A2S2NGV8   D7EM17   A0A0L0CBP5   X1WZH0   A0A2J7PDM0   A0A224XB44   A0A1Y1LKN6   A0A2J7R7D0   A0A224X6S1   D7GYA5   A0A0A9YJ00   J9LFC9   A0A0A9YU04   A0A2S2N814   A0A2M4BD67   X1WNI2   A0A2S2R9D4   A0A2M4CV42   A0A2M4BDV6   A0A224X6U5   A0A2M4CV52   V9GZF1   A0A224X6T4   K7IN67   A0A2J7QR37   A0A224XI99   A0A1Y1KFR3   A0A2M4BD83   A0A0A9YSX4   J9JS95   A0A087UGF5   A0A069DZL8   A0A2J7PBY3   A0A2J7QY69   A0A2J7PQB5   A0A2H8TF37   A0A2J7PU96   A0A1Q3G5F7   A0A2S2P698   A0A2S2PX53   A0A2J7PVX3   Q95SX7   A0A2A4K918   A0A2J7R8R8   Q8T9X4   A0A2A4IUM2   Q8I7P8   A0A1B6EGD8   A0A2J7Q6J2   A0A2H8U0H5   X1WQI9   A0A2S2Q352   A0A224XJI0   A0A224X746   A0A2S2NPG3   P21328   A0A224X6R6   A0A2S2NH02   P21329   A0A0J7MYU2   A0A2J7Q0Q6   A0A2J7QFL0  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    30086797    8387152    26108605    25401762    1327974    20075255    26334808    7753626    12537569    2463954    3040362    1714378    1701254   

EMBL

AB018558    BAA76304.1    U07847    AAA17752.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ971729    KYB24751.1    KQ973342    KXZ75569.1    GALX01005299    JAB63167.1    GALX01005359    JAB63107.1    GBBI01004395    JAC14317.1    GBBI01004571    JAC14141.1    ABLF02042518    ABLF02057746    GGMS01006359    MBY75562.1    GGMR01018716    MBY31335.1    RPOV01000134    RPJ78669.1    GFTR01008038    JAW08388.1    S59870    AAB26437.2    ABLF02029306    ABLF02029314    ABLF02060138    GGFJ01002256    MBW51397.1    GGFJ01002257    MBW51398.1    GGMS01002992    MBY72195.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GGMR01019198    MBY31817.1    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    ABLF02024246    GFTR01008279    JAW08147.1    GGMR01003407    MBY16026.1    KQ973412    EFA12510.2    JRES01000644    KNC29657.1    ABLF02034467    NEVH01026386    PNF14434.1    GFTR01008262    JAW08164.1    GEZM01053022    JAV74219.1    NEVH01006736    PNF36716.1    GFTR01008271    JAW08155.1    KQ973363    EFA13335.2    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    ABLF02023911    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GGMR01000676    MBY13295.1    GGFJ01001858    MBW50999.1    ABLF02008153    ABLF02008462    ABLF02008464    GGMS01017365    MBY86568.1    GGFL01005012    MBW69190.1    GGFJ01001857    MBW50998.1    GFTR01008251    JAW08175.1    GGFL01004957    MBW69135.1    M95171    AAA29354.1    GFTR01008261    JAW08165.1    NEVH01011985    PNF31054.1    GFTR01008256    JAW08170.1    GEZM01084969    JAV60363.1    GGFJ01001822    MBW50963.1    GBHO01008295    JAG35309.1    ABLF02028535    ABLF02028545    KK119692    KFM76444.1    GBGD01000415    JAC88474.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    NEVH01022639    PNF18527.1    GFXV01000908    MBW12713.1    NEVH01021205    PNF19912.1    GFDL01000004    JAV35041.1    GGMR01012305    MBY24924.1    GGMS01000737    MBY69940.1    NEVH01020940    PNF20481.1    AY060438    AAL25477.1    NWSH01000032    PCG80496.1    NEVH01006721    PNF37225.1    AF456125    AAL57609.1    NWSH01007753    PCG62823.1    AY180919    AAN87272.1    GEDC01000337    JAS36961.1    NEVH01017470    PNF24199.1    GFXV01007093    MBW18898.1    ABLF02022418    GGMS01002955    MBY72158.1    GFTR01008257    JAW08169.1    GFTR01008151    JAW08275.1    GGMR01006408    MBY19027.1    M22874    M38643    GFTR01008269    JAW08157.1    GGMR01003864    MBY16483.1    M38437    LBMM01013518    KMQ85605.1    NEVH01019964    PNF22161.1    NEVH01014858    PNF27387.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000037069    UP000235965    UP000002358    + More
UP000054359    UP000218220    UP000036403   

PRIDE

Q9XXW0    Q93137    Q9BPQ0    Q95SX7    Q8T9X4    Q8I7P8    + More
P21328    P21329   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139WA11   A0A139W8G9   V5GNJ2   V5GNF3   A0A023EYS8   A0A023EZE6   X1WLB2   A0A2S2QEE0   A0A2S2PPK8   A0A3N5Z7I3   A0A224XF24   Q07995   J9KKL3   A0A2M4BEF4   A0A2M4BEZ9   A0A2S2Q383   J9LC21   A0A2S2PR14   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   J9M522   A0A224X6Q4   A0A2S2NGV8   D7EM17   A0A0L0CBP5   X1WZH0   A0A2J7PDM0   A0A224XB44   A0A1Y1LKN6   A0A2J7R7D0   A0A224X6S1   D7GYA5   A0A0A9YJ00   J9LFC9   A0A0A9YU04   A0A2S2N814   A0A2M4BD67   X1WNI2   A0A2S2R9D4   A0A2M4CV42   A0A2M4BDV6   A0A224X6U5   A0A2M4CV52   V9GZF1   A0A224X6T4   K7IN67   A0A2J7QR37   A0A224XI99   A0A1Y1KFR3   A0A2M4BD83   A0A0A9YSX4   J9JS95   A0A087UGF5   A0A069DZL8   A0A2J7PBY3   A0A2J7QY69   A0A2J7PQB5   A0A2H8TF37   A0A2J7PU96   A0A1Q3G5F7   A0A2S2P698   A0A2S2PX53   A0A2J7PVX3   Q95SX7   A0A2A4K918   A0A2J7R8R8   Q8T9X4   A0A2A4IUM2   Q8I7P8   A0A1B6EGD8   A0A2J7Q6J2   A0A2H8U0H5   X1WQI9   A0A2S2Q352   A0A224XJI0   A0A224X746   A0A2S2NPG3   P21328   A0A224X6R6   A0A2S2NH02   P21329   A0A0J7MYU2   A0A2J7Q0Q6   A0A2J7QFL0  

PDB

6AR3     E-value=0.000365107,     Score=107

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

826

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.488880000000001

Exp number, first 60 AAs:

0.00045

Total prob of N-in:

0.00227

outside

1  -  826

 

 

Pi

0.301595

Theta

1.614664

Tajima's D

0

CLR

152.425684

CSRT

0.422428878556072

Interpretation

Uncertain