Gene

KWMTBOMO10899  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008478

Annotation

PREDICTED:_ribokinase-like_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr18(+):6257591-6266354      View in EpiBrowser

Full name

Ribokinase      

Location in the cell

Cytoplasmic   Reliability : 1.809 Extracellular   Reliability : 1.383

CDS

ATGGATACCAAAAATGGTTATAAACTTGTAGTTCTTGGCTCTTGTAGTGTGGATTTTACAACATATGCACCGAAACTGCCTAAATCTGGAGAAACTTTACATGGTACAAAATTCACTACCAGTTTCGGAGGAAAAGGTGCAAACCAGTGTGTTGCTGCTGCGAAATTAGGTGGAAATGCCTACATGATTTGTAGAGTGGGGGATGATCAGTGGGGTAAAAAATATAAAGACCATCTCAAAAATGAAGGTGTTAATGTGTCTTATGTTCACATCACAAAGAATGAAACAACAGGCGTAGCACAAATTGTTGTAGCAGAAAACGGAGAAAATCAAATCGTTATTGTACCGGGAGCTAATAAATGTCTAAGTGTCCAAGATGTAGAAGAGTCAATTGAATTGATAAAAAATGCTGATGTTCTAATAGGACAGCTTGAAACTCCGTTTGAAACTACTTATACAGCATTTAAGTTAAATAATGGTATAAAACTATTAAATGCCGCTCCAGCGTTGACTGATATTCGGAAAATTTTGCCATTTTGTACTATACTTTGTGTTAATGAATTAGAAGCATCAGTTCTCACTAATGTGGATGTCACCATTTCGAATGCTTCAATGGCTGCAAAAAAATTGCTGGAAACTGGCTGCGAAACAGTTATAATAACACTAGGATCTGAAGGAGCTGTTTATATGTCAAAAAACGAAGAATGTCCTAAACATGTTTTATGTGAAGCTGTTAATCCTGTAGATACCACAGGTGCCGGCGATGCTTTCATTGGAGCTTTGGCAACATTTCTGGTCGAGTATAAAGATTATCCACTGCACCAATTAATCGGCGCAGCTTGTGCGGTCGCAACCATTTCAGTTACAGTGGAAGGCACACAAACGAGTTATCCTACGAAAAATGATTTCTTTTGTAAAAAGTATGAGTACGTCCAACTGGAATAA

Protein

MDTKNGYKLVVLGSCSVDFTTYAPKLPKSGETLHGTKFTTSFGGKGANQCVAAAKLGGNAYMICRVGDDQWGKKYKDHLKNEGVNVSYVHITKNETTGVAQIVVAENGENQIVIVPGANKCLSVQDVEESIELIKNADVLIGQLETPFETTYTAFKLNNGIKLLNAAPALTDIRKILPFCTILCVNELEASVLTNVDVTISNASMAAKKLLETGCETVIITLGSEGAVYMSKNEECPKHVLCEAVNPVDTTGAGDAFIGALATFLVEYKDYPLHQLIGAACAVATISVTVEGTQTSYPTKNDFFCKKYEYVQLE

Description

Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.

Catalytic Activity

ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)

Cofactor

Mg(2+)

Subunit

Homodimer.

Similarity

Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
Belongs to the carbohydrate kinase PfkB family.

Uniprot

A0A2H1WTD3   A0A2A4J865   A0A2W1BPV4   A0A212EN32   A0A3S2LDV1   A0A194PGS7   + More
S4P727   A0A194QMG2   A0A220K8M3   U5EU95   A0A182MQH6   A0A2M4BTY5   A0A182W0V7   W5JR37   A0A0A1X5S4   A0A182FT02   A0A182Y6J7   D6WXB9   A0A034WHI3   B0X0B9   A0A182INJ9   A0A1I8NU87   Q17H56   A0A1W4WDZ1   A0A182PZV3   A0A1Q3FKN1   A0A0K8UGQ9   W8BYA7   A0A084WTS6   A0A2M4BUZ1   A0A0A1XFH1   A0A182RLD8   A0A1L8ECJ5   A0A1L8ECS4   A0A023EPD7   A0A154P6D5   R4WIW3   A0A1L8EBZ7   A0A1L8E1X0   A0A232FKH2   A0A182PCC4   A0A1L8E1M4   A0A182VEN7   A0A023EPF3   A0A182NRG7   A0A1I8MI95   K7J480   A0A0P4VXF9   A0A0K8VLV4   A0A158NGU0   A0A182UIL9   F4WZP8   W8CBB7   E9IUQ2   A0A182HSJ4   A0A0L0C667   A0A0K8TMI2   Q7QCF9   A0A182XAQ4   B4JK94   A0A1B6BYR2   A0A026W9W0   B3P982   E2BVL2   A0A0A9WXY4   E2AJB5   A0A1Y1M6B7   A0A0K8SLC0   B4PX14   A0A1W7R8J4   A0A3M6T4E6   O77425   A0A3B0JDK0   Q29I50   A0A2B4RFF0   B3MYB0   B4I938   R4FND1   B4M9X8   A0A0M5JE21   A0A034WK55   A0A2A3ECU7   L8I2X8   B4NEA9   A0A088ARF3   A0A1U7UQC7   A0A2Y9HNP7   A0A182JYQ6   M3W036   W5QDU7   A0A3P9A491   G1KWF4   G1SZT1   A0A1B0AFE2   A0A369SKR6   A0A0L7R4A1   A0A0P4VJH2   A0A151XCW2   A0A1B0GQU7   A0A3Q7NR74  

EC Number

2.7.1.15

Pubmed

28756777    22118469    26354079    23622113    28630352    20920257    + More
23761445    25830018    25244985    18362917    19820115    25348373    17510324    24495485    24438588    24945155    23691247    28648823    25315136    20075255    21347285    21719571    21282665    26108605    26369729    12364791    14747013    17210077    17994087    24508170    20798317    25401762    26823975    28004739    17550304    30382153    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    15632085    22751099    17975172    20809919    25069045    21993624    30042472    27129103   

EMBL

ODYU01010526    SOQ55694.1    NWSH01002670    PCG67714.1    KZ149999    PZC75347.1    + More
AGBW02013764    OWR42861.1    RSAL01000195    RVE44565.1    KQ459604    KPI92591.1    GAIX01004779    JAA87781.1    KQ461196    KPJ06544.1    MF319724    ASJ26438.1    GANO01002422    JAB57449.1    AXCM01000145    GGFJ01007396    MBW56537.1    ADMH02000418    ETN66586.1    GBXI01008269    JAD06023.1    KQ971361    EFA08820.2    GAKP01004803    JAC54149.1    DS232232    EDS38080.1    CH477253    EAT45957.1    AXCN02001460    GFDL01006908    JAV28137.1    GDHF01030759    GDHF01026465    JAI21555.1    JAI25849.1    GAMC01004962    JAC01594.1    ATLV01026914    KE525420    KFB53620.1    GGFJ01007692    MBW56833.1    GBXI01004612    JAD09680.1    GFDG01002349    JAV16450.1    GFDG01002353    JAV16446.1    GAPW01002737    JAC10861.1    KQ434826    KZC07401.1    AK417425    BAN20640.1    GFDG01002654    JAV16145.1    GFDF01001455    JAV12629.1    NNAY01000080    OXU31165.1    GFDF01001454    JAV12630.1    GAPW01002717    JAC10881.1    AAZX01010390    GDRN01089668    GDRN01089666    JAI60615.1    GDHF01012452    JAI39862.1    ADTU01015211    GL888480    EGI60323.1    GAMC01004961    JAC01595.1    GL766012    EFZ15684.1    APCN01000281    JRES01000948    KNC26904.1    GDAI01002039    JAI15564.1    AAAB01008859    EAA08069.5    CH916370    EDV99996.1    GEDC01030886    GEDC01018566    JAS06412.1    JAS18732.1    KK107314    EZA52835.1    CH954183    EDV45378.1    GL450875    EFN80282.1    GBHO01032211    GBHO01018892    GDHC01002807    JAG11393.1    JAG24712.1    JAQ15822.1    GL439972    EFN66436.1    GEZM01042455    JAV79845.1    GBRD01011713    JAG54111.1    CM000162    EDX00800.1    GEHC01000192    JAV47453.1    RCHS01004356    RMX35519.1    AE014298    BT021233    AL031581    AAF45527.1    AAX33381.1    CAA20884.1    OUUW01000003    SPP78212.1    CH379064    EAL31556.2    LSMT01000497    PFX17094.1    CH902632    EDV32604.1    CH480825    EDW43719.1    ACPB03015647    GAHY01001344    JAA76166.1    CH940655    EDW66037.1    CP012528    ALC49981.1    GAKP01004805    GAKP01004804    JAC54148.1    KZ288282    PBC29603.1    JH882185    ELR50466.1    CH964239    EDW82078.1    AANG04003329    AMGL01075890    AMGL01075891    AMGL01075892    AMGL01075893    AMGL01075894    AMGL01075895    AAGW02005705    AAGW02005706    AAGW02005707    AAGW02005708    AAGW02005709    NOWV01000003    RDD47485.1    KQ414657    KOC65678.1    GDKW01001444    JAI55151.1    KQ982294    KYQ58214.1    AJVK01019348   

Proteomes

UP000218220    UP000007151    UP000283053    UP000053268    UP000053240    UP000075883    + More
UP000075920    UP000000673    UP000069272    UP000076408    UP000007266    UP000002320    UP000075880    UP000095300    UP000008820    UP000192223    UP000075886    UP000030765    UP000075900    UP000076502    UP000215335    UP000075885    UP000075903    UP000075884    UP000095301    UP000002358    UP000005205    UP000075902    UP000007755    UP000075840    UP000037069    UP000007062    UP000076407    UP000001070    UP000053097    UP000008711    UP000008237    UP000000311    UP000002282    UP000275408    UP000000803    UP000268350    UP000001819    UP000225706    UP000007801    UP000001292    UP000015103    UP000008792    UP000092553    UP000242457    UP000007798    UP000005203    UP000189704    UP000248481    UP000075881    UP000011712    UP000002356    UP000265140    UP000001646    UP000001811    UP000092445    UP000253843    UP000053825    UP000075809    UP000092462    UP000286641   

PRIDE

O77425   

Pfam

PF00294   PfkB

Interpro

IPR011611   PfkB_dom        + More
IPR002139   Ribo/fructo_kinase       
IPR002173   Carboh/pur_kinase_PfkB_CS       
IPR029056   Ribokinase-like       
IPR011877   D_ribokin       

SUPFAM

SSF53613   SSF53613       

Gene 3D

3.40.1190.20    

CDD

cd01174  ribokinase

ProteinModelPortal

A0A2H1WTD3   A0A2A4J865   A0A2W1BPV4   A0A212EN32   A0A3S2LDV1   A0A194PGS7   + More
S4P727   A0A194QMG2   A0A220K8M3   U5EU95   A0A182MQH6   A0A2M4BTY5   A0A182W0V7   W5JR37   A0A0A1X5S4   A0A182FT02   A0A182Y6J7   D6WXB9   A0A034WHI3   B0X0B9   A0A182INJ9   A0A1I8NU87   Q17H56   A0A1W4WDZ1   A0A182PZV3   A0A1Q3FKN1   A0A0K8UGQ9   W8BYA7   A0A084WTS6   A0A2M4BUZ1   A0A0A1XFH1   A0A182RLD8   A0A1L8ECJ5   A0A1L8ECS4   A0A023EPD7   A0A154P6D5   R4WIW3   A0A1L8EBZ7   A0A1L8E1X0   A0A232FKH2   A0A182PCC4   A0A1L8E1M4   A0A182VEN7   A0A023EPF3   A0A182NRG7   A0A1I8MI95   K7J480   A0A0P4VXF9   A0A0K8VLV4   A0A158NGU0   A0A182UIL9   F4WZP8   W8CBB7   E9IUQ2   A0A182HSJ4   A0A0L0C667   A0A0K8TMI2   Q7QCF9   A0A182XAQ4   B4JK94   A0A1B6BYR2   A0A026W9W0   B3P982   E2BVL2   A0A0A9WXY4   E2AJB5   A0A1Y1M6B7   A0A0K8SLC0   B4PX14   A0A1W7R8J4   A0A3M6T4E6   O77425   A0A3B0JDK0   Q29I50   A0A2B4RFF0   B3MYB0   B4I938   R4FND1   B4M9X8   A0A0M5JE21   A0A034WK55   A0A2A3ECU7   L8I2X8   B4NEA9   A0A088ARF3   A0A1U7UQC7   A0A2Y9HNP7   A0A182JYQ6   M3W036   W5QDU7   A0A3P9A491   G1KWF4   G1SZT1   A0A1B0AFE2   A0A369SKR6   A0A0L7R4A1   A0A0P4VJH2   A0A151XCW2   A0A1B0GQU7   A0A3Q7NR74  

PDB

2FV7     E-value=4.49192e-56,     Score=550

KEGG

101745091    K00852 ribokinase [EC:2.7.1.15] | (RefSeq) ribokinase-like

PATHWAY

00030    Pentose phosphate pathway - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0019303   GO:0004747   GO:0005737   GO:0005634   GO:0005524   GO:0046872   GO:0006014   GO:0046835   GO:0016773   GO:0006412   GO:0043015   GO:0005515   GO:0051028   GO:0005622   GO:0006810   GO:0003824   GO:0016301  

Subcellular location

Cytoplasm  
Nucleus  

Length:

314

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.54958

Exp number, first 60 AAs:

0.05655

Total prob of N-in:

0.06602

outside

1  -  314

 

 

Pi

375.702467

Theta

207.150625

Tajima's D

2.273843

CLR

0.24481

CSRT

0.92040397980101

Interpretation

Possibly Positive selection