Gene

KWMTBOMO10891

Pre Gene Modal

BGIBMGA008475

Annotation

PREDICTED:_protein_SMG9_[Bombyx_mori]

Location

Bomo_Chr18(+):6136111-6143489      View in EpiBrowser

Full name

Protein SMG9      

Alternative Name

Protein smg-9 homolog

Location in the cell

Nuclear   Reliability : 4.051

CDS

ATGGCCGATAAAAAGAAAAAACCTTTCCTACCCAAGGAGCCCACAACTCCAAGACGGCCAGTAATTTTAAAATCAGAACGTGATAATTCAAATAAAGAGGCAACAAAAGAGAAAGAAAAAGAAAAACAACCCACCATAATTTTAAAAACTCGGGAACAAAGTACTCCCAAAGATGAAATACCTCAAAGCCCTAAAATTTCTAAAACATCAAACCTTGAAGCGGAAGGGCCTCATCCATCTAAAATAGTTCAGAATGAAAATAAAGAGAAAAAGACGATAGAACAAAAAGTTAGTCCTCCCTTAAAACCAATGCTGGAGCCAGTGAAACTATTAGACAAACATTTTGTATTTAATTCAGGAGCCTTGGAGTTCCTGCATGACTCAAGTACAAACTATTTAGTTGTTGGAATCATAGGAACTCAAGGTGTTGGTAAATCAACAATACTCAATCTGATAGCACAAAACAAATTTGACCAAAACCTATGTAGTGAAATTCTAAATTCCCATGAGGCACCAGAGGGTGTATATGAAACAAATGTAATGGCTAATATTGAAAATCAATCAGATAATCTTGATTTAATACAGCCACAAGAACCGAAAATCGATAAGAATACACTTTCAAAGTTTAAAATACAAGATATTGAACAAATTGAAAGAGGCGTTCACTGTACCAAAGGTATCGATATGTACATAACAAACGATCGTGTTATCCTTCTGGATTGTCAAGCTCTTTGGTCACCATCTTTAATAGAAGACAGCATGCCTCCTATAAAATCGAAAAGCTCTAATGAAATCACAGTAGAATGTCTTCAGATAGCTTCATTCCTAATGGCTATATGTCATGTGCTTATTGCAGTCCAGGATTGGTTTACAGATTATAATTTTATTAGATACATTCAAACAGCGGAGATGTTAAAGCCTTCACTATCGGCTTCAAATACTATTTCGAACCAAGAAGGTTCAGAATCGACGGCCATTGGTGAGAACCAGCCCCACTTGCTGCTTCTACATAACAGATGTCAGCTAGAAGATTATACACCCGAATCCATTAAAATTATGCAAGATCTTTACAGAAAGGCGTTCCAAAAGTCGTCACTGCAGCTAAACTCTGGAATGTACATGTACAGCGATACGAATCGAAACGGATTGAATGTAGATAGCGTATGCAAGAGCTACAACGTGGAAACGTGCGGTTCACCCATAAATATGTTCCTACTGCCCGAAGTATACGAGGATTATGATAACGTAGACATTTATCGCGGGCATCCACCTTTCGAGCAACTCGCAAAACGACTGCGCTGGATGGTGCTCGGAGTCAACAAGCATCAGATCACAAACGTTCCCAACTTATCGGAACGAGGATGGCTCCAGTACTGCAGCAAAGCTTGGGAAACAATAAGAAAGTGCACTTTCTTCATGGAATACGAGAGGTTCTTACCGTATTAA

Protein

MADKKKKPFLPKEPTTPRRPVILKSERDNSNKEATKEKEKEKQPTIILKTREQSTPKDEIPQSPKISKTSNLEAEGPHPSKIVQNENKEKKTIEQKVSPPLKPMLEPVKLLDKHFVFNSGALEFLHDSSTNYLVVGIIGTQGVGKSTILNLIAQNKFDQNLCSEILNSHEAPEGVYETNVMANIENQSDNLDLIQPQEPKIDKNTLSKFKIQDIEQIERGVHCTKGIDMYITNDRVILLDCQALWSPSLIEDSMPPIKSKSSNEITVECLQIASFLMAICHVLIAVQDWFTDYNFIRYIQTAEMLKPSLSASNTISNQEGSESTAIGENQPHLLLLHNRCQLEDYTPESIKIMQDLYRKAFQKSSLQLNSGMYMYSDTNRNGLNVDSVCKSYNVETCGSPINMFLLPEVYEDYDNVDIYRGHPPFEQLAKRLRWMVLGVNKHQITNVPNLSERGWLQYCSKAWETIRKCTFFMEYERFLPY

Description

Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with smg1 and smg8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between smg1 and smg8 (By similarity).

Subunit

Component of the SMG1C complex composed of smg1, smg8 and smg9.

Similarity

Belongs to the SMG9 family.

Keywords

Complete proteome   Nonsense-mediated mRNA decay   Reference proteome  

Feature

chain  Protein SMG9

Uniprot

A0A2A4K990   A0A2H1WXK1   A0A2W1BUD4   A0A194QSN6   I4DPW0   A0A212EMY6   + More
A0A2J7PG05   A0A1Y1MQN3   A0A067QJF6   A0A0T6B254   A0A2J7PG11   A0A0L7KMJ4   A0A1B6E5D5   A0A3B4D3M6   A0A1B6K1W7   A0A087T2N3   W5LAK0   A0A3B3R7E4   A0A2D0QZN5   A0A3Q1I0V9   A0A3Q1I616   A0A3Q1FT52   A0A3P8TDY1   B5DDX6   A0A3Q1APN9   A0A3Q1I498   A0A3Q2YPV5   A0A2D0QZP4   A0A3B4UC57   A0A3Q3F3A0   A0A1S3HPQ0   H2UNR6   A0A3Q4GWK8   A0A3P8RB66   A0A2I4BWF4   A0A3Q3MN04   A0A3B4XV50   A0A1A7WV73   A0A3Q0RPU2   A0A293N237   A0A1W4YGW5   A0A3B4F3A5   A0A1W4YHA8   E7F7F6   A0A0C9S0L9   G3NXC9   A0A3Q2QH93   A0A1E1XTS9   A0A3Q3C6P6   A0A3P8R8K3   A0A146N9L0   M4A826   X1WD43   A0A2T7P4I9   A0A3Q3WZ93   A0A3Q3AMQ2   A0A2U9AYQ1   A0A2U9AYY8   A0A060X1R7   A0A1S3RYF4   B5X165   A0A3Q3ALD6   A0A3B3TZ42   A0A3B4BLC6   A0A131XWS8   A0A023GK96   A0A147BDX5   A0A1S3RY62   A0A3P9N922   A0A146NAS7   H3CJ69   A0A146Y0D5   A0A315WDX7   A0A1S3RX77   A0A087XNM8   A0A3B3XXT1   A0A096LSQ4   A0A3B3XY81   A0A3P8V278   A0A232EKR4   G3MKC0   K7J3R4   A0A1E1XD20   L7M863   A0A3Q1FT24   A0A3B3CFT2   A0A224YX65   A0A1A8G8U4   Q05AW9   A0A3P9C4G1   A0A3P8TAW5   A0A131YL14   A0A3P9ITI1   H2LPK9   A0A3P9MIR0  

Pubmed

28756777    26354079    22651552    22118469    28004739    24845553    + More
26227816    25329095    29240929    21551351    25186727    23594743    29209593    23542700    24755649    20433749    25463417    29652888    15496914    29703783    24487278    28648823    22216098    20075255    28503490    25576852    29451363    28797301    26830274    17554307   

EMBL

NWSH01000044    PCG80300.1    ODYU01011783    SOQ57727.1    KZ149999    PZC75353.1    + More
KQ461196    KPJ06551.1    AK403806    BAM19950.1    AGBW02013764    OWR42854.1    NEVH01025635    PNF15266.1    GEZM01024105    JAV87972.1    KK853289    KDR08908.1    LJIG01016261    KRT81133.1    PNF15267.1    JTDY01008544    KOB64522.1    GEDC01014557    GEDC01004148    JAS22741.1    JAS33150.1    GECU01002275    JAT05432.1    KK113116    KFM59372.1    BC168445    HADW01008233    HADX01015849    SBP09633.1    GFWV01021540    MAA46268.1    BX005256    GBYB01014121    JAG83888.1    GFAA01000781    JAU02654.1    GCES01157894    JAQ28428.1    PZQS01000006    PVD28328.1    CP026243    AWO96819.1    AWO96817.1    FR904735    CDQ70795.1    BT044784    GEFM01005680    JAP70116.1    GBBM01001061    JAC34357.1    GEGO01006437    JAR88967.1    GCES01157895    JAQ28427.1    GCES01038784    JAR47539.1    NHOQ01000034    PWA33608.1    AYCK01007845    NNAY01003721    OXU18954.1    JO842321    AEO33938.1    GFAC01002202    JAT96986.1    GACK01004814    JAA60220.1    GFPF01011072    MAA22218.1    HAEB01020267    HAEC01001076    SBQ66794.1    BC123225    GEDV01008564    JAP79993.1   

Proteomes

UP000218220    UP000053240    UP000007151    UP000235965    UP000027135    UP000037510    + More
UP000261440    UP000054359    UP000018467    UP000261540    UP000221080    UP000265040    UP000257200    UP000265080    UP000008143    UP000257160    UP000264820    UP000261420    UP000261660    UP000085678    UP000005226    UP000261580    UP000265100    UP000192220    UP000261640    UP000261360    UP000261340    UP000192224    UP000261460    UP000000437    UP000007635    UP000265000    UP000264840    UP000002852    UP000245119    UP000261620    UP000264800    UP000246464    UP000193380    UP000087266    UP000261500    UP000261520    UP000242638    UP000007303    UP000028760    UP000261480    UP000265120    UP000215335    UP000002358    UP000261560    UP000265160    UP000265200    UP000001038    UP000265180   

PRIDE

E7F7F6    B5X165   

Pfam

PF01395   PBP_GOBP        + More
PF10220   Smg8_Smg9

Interpro

IPR039177   SMG9        + More
IPR027417   P-loop_NTPase       
IPR006170   PBP/GOBP       
IPR036728   PBP_GOBP_sf       
IPR019354   Smg8/Smg9       

SUPFAM

SSF52540   SSF52540        + More
SSF47565   SSF47565       

Gene 3D

1.10.238.20    

ProteinModelPortal

A0A2A4K990   A0A2H1WXK1   A0A2W1BUD4   A0A194QSN6   I4DPW0   A0A212EMY6   + More
A0A2J7PG05   A0A1Y1MQN3   A0A067QJF6   A0A0T6B254   A0A2J7PG11   A0A0L7KMJ4   A0A1B6E5D5   A0A3B4D3M6   A0A1B6K1W7   A0A087T2N3   W5LAK0   A0A3B3R7E4   A0A2D0QZN5   A0A3Q1I0V9   A0A3Q1I616   A0A3Q1FT52   A0A3P8TDY1   B5DDX6   A0A3Q1APN9   A0A3Q1I498   A0A3Q2YPV5   A0A2D0QZP4   A0A3B4UC57   A0A3Q3F3A0   A0A1S3HPQ0   H2UNR6   A0A3Q4GWK8   A0A3P8RB66   A0A2I4BWF4   A0A3Q3MN04   A0A3B4XV50   A0A1A7WV73   A0A3Q0RPU2   A0A293N237   A0A1W4YGW5   A0A3B4F3A5   A0A1W4YHA8   E7F7F6   A0A0C9S0L9   G3NXC9   A0A3Q2QH93   A0A1E1XTS9   A0A3Q3C6P6   A0A3P8R8K3   A0A146N9L0   M4A826   X1WD43   A0A2T7P4I9   A0A3Q3WZ93   A0A3Q3AMQ2   A0A2U9AYQ1   A0A2U9AYY8   A0A060X1R7   A0A1S3RYF4   B5X165   A0A3Q3ALD6   A0A3B3TZ42   A0A3B4BLC6   A0A131XWS8   A0A023GK96   A0A147BDX5   A0A1S3RY62   A0A3P9N922   A0A146NAS7   H3CJ69   A0A146Y0D5   A0A315WDX7   A0A1S3RX77   A0A087XNM8   A0A3B3XXT1   A0A096LSQ4   A0A3B3XY81   A0A3P8V278   A0A232EKR4   G3MKC0   K7J3R4   A0A1E1XD20   L7M863   A0A3Q1FT24   A0A3B3CFT2   A0A224YX65   A0A1A8G8U4   Q05AW9   A0A3P9C4G1   A0A3P8TAW5   A0A131YL14   A0A3P9ITI1   H2LPK9   A0A3P9MIR0  

PDB

5NKM     E-value=3.74069e-10,     Score=156

KEGG

101744801    K18735 protein SMG9 | (RefSeq) protein SMG9

GO

GO:0000184   GO:0005549   GO:0016021  

PANTHER

PTHR14270  

Length:

481

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.5064

Exp number, first 60 AAs:

0

Total prob of N-in:

0.02142

outside

1  -  481

 

 

Pi

175.528385

Theta

171.800362

Tajima's D

0.152942

CLR

14.514579

CSRT

0.413729313534323

Interpretation

Uncertain