Gene

KWMTBOMO10878

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr18(+):5952528-5954752      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS       + More
RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.342

CDS

ATGGTTAGGAATGACAGACTCACCGCCTCCAAAGGCGGGACTGCCATTTACTATAGGCGGGCCCTGCACGTTGTCCCTCTCGATACCCCCTCGCTCTCACATATCGAGGCGTCAGTGTGCCGTATCTCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCGGACAAGCCCCTTCTGAGCAGTGACATCGAGTCACTGTTCGGCATGGGAGACTCCGTCATCCTGGCAGGCGATTTAAATTGCCACCATACTAGGTGGAACTGCCACAGTTCAAACATAAACGGTAGGCGTCTCGACGCGTTTATAGATGACCTTACCTTTGAAGTAGTCGGTCCCCCAACTCCAACATGTTATCCGTATAACATCGCGCTCCGTCCGAGCACTATAGACCTGGCACTGCTGAGGAACGTAACTCTGCGCTTGCGTTCCATCGAAGCAATGTCAGAGCTCGACTCAGACCACCGACCTGTCGTTATGCAGCTCGGTCGCCCCCACAACCCAGTCACAGCTACGAGGACCATGGTGGACTGGAAGAAGCTGGGCAAATGCTTAGCCGATGCCGCTCCACCAATCCTCCCCTGCGGCCCGGATTCAACTCCATCCCCCGAGGACACAGTCGAATCCATAAACATCATCACGGATCACATCTCTTCCGCGATCATAAGATCCTCAAAAGAAGTCGATGTGGAGGATAGCTTCCACCGCATCAGACTGTCCCCCGAACTTAGGAACCTCCTAAGAGTTAGAAACGCGGCAATCCGGGCCTACGATCAACTTCCCACGCACTCAAACCGGATTCGGATGCGTCGTCTACAGCGGGATGTAAAATCTCGCCTAAGCGACGCCCGAAATGAGAATTGGGATAGTTACTTAGAAGGACTCGCGCCCTCTCATCAAGCATACTGGCGACTAGCAAGGACTCTCAAGTCCGAAACTACCGCTACTATGCCTCCTCTCGTACGCCCTTCAGGCCAACCACCGGCTTTCGATGACGATGACAAGGCAGAGTTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAATACGCGGACCCCGAACACACCGAGGCAGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCACCCTCGGACGCGTTACCCCCCATTACCTCTGACGAAGTTAGAGAAGTAATAGATAACCTTCAACCTAAGAAGGCACCCGGCTCCGACGGCATCCGCAACCGCGCGTTAAAACTCTTACCAGTCCAACTGATAACAATGTTGGCTACCATCTTAAATGCCGCTATGACGCACTGCATCTTTCCGGCGGTATGGAAAGAAGCGGACGTTATCGGTATACACAAGCCGGACAAACCGAATAATGAAACCGCTAGTTACCGACCGATTAGTCTCCTCCCAGCGATAGGCAAAATTTACGAACGGCTCCTTCGGAAACGCCTCTGGGACTTCGTTACCGCGAATAAAATTCTAATAGACGAGCAGTTTGGATTCCGCGCCAAACACTCGTGCGTACAACAAGTGCACCGCCTCACGGAGCACATCTTAATAGGGCTAAATAGGCGTAAACAAATCCCGACCGGCGCCCTCTTCTTCGATGTAGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTGATCTACAAACTGTACAACATGGGAGTGCCAGACAGACTCGTGCTCATCATACGAGACTTCTTATCGAACCGTTCGTTTCGATATCGAGTAGAGGGAACTCGTTCTCGTCCCCGTCATCTGACTGCCGGAGTCCCGCAAGGCTCCGCACTCTCCCCGTTACTATTTAGTTTGTATATCAACGATATACCCCGGTCTCCGGAGACCCATCTAGCGCTCTTCGCCGATGACACGGCTATCTACTACTCGTGTAGGAAGATGTCGTTGCTTCATCGGCGACTCCAGACCGCAGTAACCACCATGGGACAGTGGTTCCGGAAGTGGCGAATAGACATTAACCCACGAAAAGCACAGCGGTGCTATTCAAAAGGGGTCGCCCTCCGAATACCACTTCGAGCACCCCACTCCCCAGTAGGCGCGTAA

Protein

MVRNDRLTASKGGTAIYYRRALHVVPLDTPSLSHIEASVCRISLTGHQPIVIASVYLPPDKPLLSSDIESLFGMGDSVILAGDLNCHHTRWNCHSSNINGRRLDAFIDDLTFEVVGPPTPTCYPYNIALRPSTIDLALLRNVTLRLRSIEAMSELDSDHRPVVMQLGRPHNPVTATRTMVDWKKLGKCLADAAPPILPCGPDSTPSPEDTVESINIITDHISSAIIRSSKEVDVEDSFHRIRLSPELRNLLRVRNAAIRAYDQLPTHSNRIRMRRLQRDVKSRLSDARNENWDSYLEGLAPSHQAYWRLARTLKSETTATMPPLVRPSGQPPAFDDDDKAELLADALQEQCTTSTQYADPEHTEAVDREVERRASLPPSDALPPITSDEVREVIDNLQPKKAPGSDGIRNRALKLLPVQLITMLATILNAAMTHCIFPAVWKEADVIGIHKPDKPNNETASYRPISLLPAIGKIYERLLRKRLWDFVTANKILIDEQFGFRAKHSCVQQVHRLTEHILIGLNRRKQIPTGALFFDVAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDFLSNRSFRYRVEGTRSRPRHLTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKMSLLHRRLQTAVTTMGQWFRKWRIDINPRKAQRCYSKGVALRIPLRAPHSPVGA

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A139W8G9   + More
A0A1Y1NA23   A0A139WA11   D7EM17   A0A023EYS8   A0A2S2PPK8   A0A023EZE6   J9LC21   A0A1Y1K0C8   V5GNJ2   A0A2S2PA10   X1WXR6   X1WLB2   A0A2S2QEE0   A0A2S2Q383   Q07995   V5GNF3   D7GYA5   V9H092   J9LFC9   A0A3N5Z7I3   X1WZH0   A0A2J7RE85   K7IN67   A0A2S2NJB5   A0A224X6Q4   A0A224X6S1   A0A2J7PU96   A0A2J7QR37   A0A2J7R7D0   J9M522   A0A224XB44   A0A2J7QY69   A0A2J7PBY3   A0A2J7PP17   A0A2M4CV52   A0A224X6T4   A0A2M4CV42   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A2S2NCK2   A0A2S2NGV8   J9KLB1   A0A2S2R9D4   A0A2S2P698   J9JS95   A0A224X6R6   A0A0H3UA66   A0A224X746   A0A224XI99   A0A2J7Q6J2   A0A224X6W2   A0A2S2Q2R8   A0A069DX78   A0A2S2P6S3   A0A224X7Z3   A0A2M4BEF4   A0A2S2N814   A0A2S2PEZ9   A0A087U3K8   A0A2M4BEZ9   A0A2S2P6C4   A0A224X6U5   A0A1B0CHA5   A0A2S2N6Q7   A0A087UCW3   A0A2S2PJG2   A0A2S2NPG3   A0A224XHW8   A0A2S2PUS3   A0A146KV64   A0A0J7MTN6   A0A224XJI0   X1WXE6   A0A087T3W0   A0A0V0G5B6   A0A1Y1LKN6   A0A2J7PDM0   A0A2J7RMG0   A0A1Y1KFR3   Q95SX7   J9KWJ0   A0A2H8TKI9   P21329   A0A1B6C2V8   A0A0A9YU04   A0A0A9YJ00   A0A2J7PQB5   A0A3S2NJ07   X1WQI9   A0A224XIV5   A0A2S2P7B2  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    18362917    19820115    28004739    + More
25474469    8387152    9061921    30086797    20075255    26812285    26334808    26823975    7753626    12537569    1701254    25401762   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    KQ973342    KXZ75569.1    GEZM01008457    JAV94772.1    KQ971729    KYB24751.1    KQ973412    EFA12510.2    GBBI01004395    JAC14317.1    GGMR01018716    MBY31335.1    GBBI01004571    JAC14141.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GEZM01099921    GEZM01099920    GEZM01099918    GEZM01099906    JAV53125.1    GALX01005299    JAB63167.1    GGMR01013409    MBY26028.1    ABLF02008605    ABLF02008608    ABLF02008609    ABLF02008610    ABLF02017023    ABLF02042518    ABLF02057746    GGMS01006359    MBY75562.1    GGMS01002992    MBY72195.1    S59870    AAB26437.2    GALX01005359    JAB63107.1    KQ973363    EFA13335.2    L79944    AAB04627.1    ABLF02023911    RPOV01000134    RPJ78669.1    ABLF02034467    NEVH01005277    PNF39135.1    GGMR01004661    MBY17280.1    GFTR01008279    JAW08147.1    GFTR01008271    JAW08155.1    NEVH01021205    PNF19912.1    NEVH01011985    PNF31054.1    NEVH01006736    PNF36716.1    ABLF02024246    GFTR01008262    JAW08164.1    NEVH01009134    PNF33528.1    NEVH01027074    PNF13841.1    NEVH01023280    PNF18085.1    GGFL01004957    MBW69135.1    GFTR01008261    JAW08165.1    GGFL01005012    MBW69190.1    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    GGMR01002322    MBY14941.1    GGMR01003407    MBY16026.1    ABLF02040174    ABLF02040183    ABLF02055266    GGMS01017365    MBY86568.1    GGMR01012305    MBY24924.1    ABLF02028535    ABLF02028545    GFTR01008269    JAW08157.1    KF280391    AIE77315.1    GFTR01008151    JAW08275.1    GFTR01008256    JAW08170.1    NEVH01017470    PNF24199.1    GFTR01008260    JAW08166.1    GGMS01002786    MBY71989.1    GBGD01000389    JAC88500.1    GGMR01012443    MBY25062.1    GFTR01007929    JAW08497.1    GGFJ01002256    MBW51397.1    GGMR01000676    MBY13295.1    GGMR01015412    MBY28031.1    KK118005    KFM71947.1    GGFJ01002257    MBW51398.1    GGMR01012283    MBY24902.1    GFTR01008251    JAW08175.1    AJWK01012157    GGMR01000226    MBY12845.1    KK119261    KFM75202.1    GGMR01016905    MBY29524.1    GGMR01006408    MBY19027.1    GFTR01008254    JAW08172.1    GGMR01020516    MBY33135.1    GDHC01018248    JAQ00381.1    LBMM01018163    KMQ83860.1    GFTR01008257    JAW08169.1    ABLF02016634    KK113281    KFM59799.1    GECL01003538    JAP02586.1    GEZM01053022    JAV74219.1    NEVH01026386    PNF14434.1    NEVH01002556    PNF42024.1    GEZM01084969    JAV60363.1    AY060438    AAL25477.1    ABLF02021819    ABLF02021820    ABLF02055326    GFXV01002840    MBW14645.1    M38437    GEDC01029594    JAS07704.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    NEVH01022639    PNF18527.1    RSAL01000708    RVE41206.1    ABLF02022418    GFTR01007904    JAW08522.1    GGMR01012676    MBY25295.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000002358    UP000054359    + More
UP000092461    UP000036403    UP000283053   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q95SX7    P21329   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2
PF10551   MULE

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       
IPR013083   Znf_RING/FYVE/PHD       
IPR018289   MULE_transposase_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10     3.30.40.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A139W8G9   + More
A0A1Y1NA23   A0A139WA11   D7EM17   A0A023EYS8   A0A2S2PPK8   A0A023EZE6   J9LC21   A0A1Y1K0C8   V5GNJ2   A0A2S2PA10   X1WXR6   X1WLB2   A0A2S2QEE0   A0A2S2Q383   Q07995   V5GNF3   D7GYA5   V9H092   J9LFC9   A0A3N5Z7I3   X1WZH0   A0A2J7RE85   K7IN67   A0A2S2NJB5   A0A224X6Q4   A0A224X6S1   A0A2J7PU96   A0A2J7QR37   A0A2J7R7D0   J9M522   A0A224XB44   A0A2J7QY69   A0A2J7PBY3   A0A2J7PP17   A0A2M4CV52   A0A224X6T4   A0A2M4CV42   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A2S2NCK2   A0A2S2NGV8   J9KLB1   A0A2S2R9D4   A0A2S2P698   J9JS95   A0A224X6R6   A0A0H3UA66   A0A224X746   A0A224XI99   A0A2J7Q6J2   A0A224X6W2   A0A2S2Q2R8   A0A069DX78   A0A2S2P6S3   A0A224X7Z3   A0A2M4BEF4   A0A2S2N814   A0A2S2PEZ9   A0A087U3K8   A0A2M4BEZ9   A0A2S2P6C4   A0A224X6U5   A0A1B0CHA5   A0A2S2N6Q7   A0A087UCW3   A0A2S2PJG2   A0A2S2NPG3   A0A224XHW8   A0A2S2PUS3   A0A146KV64   A0A0J7MTN6   A0A224XJI0   X1WXE6   A0A087T3W0   A0A0V0G5B6   A0A1Y1LKN6   A0A2J7PDM0   A0A2J7RMG0   A0A1Y1KFR3   Q95SX7   J9KWJ0   A0A2H8TKI9   P21329   A0A1B6C2V8   A0A0A9YU04   A0A0A9YJ00   A0A2J7PQB5   A0A3S2NJ07   X1WQI9   A0A224XIV5   A0A2S2P7B2  

PDB

6AR3     E-value=0.0102806,     Score=94

KEGG

105842435    no KO assigned | (RefSeq) uncharacterized LOC105842435

GO

GO:0003964   GO:0004519   GO:0016021   GO:0006313  

Length:

687

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.942669999999999

Exp number, first 60 AAs:

0.00737

Total prob of N-in:

0.01055

outside

1  -  687

 

 

Pi

0.000438

Theta

0.004133

Tajima's D

0

CLR

1.031121

CSRT

0.00829958502074896

Interpretation

Uncertain