Gene

KWMTBOMO10867

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr18(-):5669979-5674737      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon X-element       + More
RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.388 Nuclear   Reliability : 1.891

CDS

ATGGACGCTGTATTCGCGGAATTCCTCCGACTTCGCCACCCACAGCTCGCCTCAGAGTTTCTGGCCTTCAAGGCCAATCACACTGCGAGCCCTCTCGAGGACTCCGCCGCGCTCGCTGCTCCTGCGTCGCCTGTACCTGCGTGCAGAGCTTCTGCATTGAGCACCGCAGCCTCTGTCGTGCCTGCCGCTCCCGTGTCGCCTATACTGGCGAGAAAAGCTGCTGCGTCGTCCGCCGTGACCATCGTTTCAGCTGAGCGATCATCCGCGGCCTCCGTCGCGCCCTCTAAAACACCTACACTTGCTCGTAGGTCGCCTGCACCCGCCTCCTCGTGCTCCGACTCTGACTCGGACATGGAGGTCGACCTCGCCCCCGCCTCATCGACGGATGGATTCACCCTGGTACAGAAGGGTAAGAAGCGTGCCGCGGAGTCTCGAGCTCCCGCGGCCGCTAAAATTAGCAAAGCCGTGAACGCGTCGCGCCCCCGCCCTCAGACTCCCGTTGCGCCCCCAGCCCGTGCCACTCCGTCGCCGCGTCCGGTGGCACAAAATAAAACCCAGACCCCTCCCCCGGTTATCCTTCAGGAGAAGGCAGCTTGGGATCGAGTTTGCCTGGCCCTTAAGGCCAAAAATATAAATTTCACGAATGCCCGTAACCTCGCGAACGGCATTCAAATTAAGGTTCAAACACCCGACGACCATAGGGCCCTCTCTTCTTACCTCCGTAAGGAGCGTATAAGTTTCCATACGTATACGCTCCAGGAGGAGCGCGAACTCCGAGTTGTAATACGCGGAATCCCTAAAGAGTTAGATGTAGAGCTCGTAAAAGCCGACCTGTTAGAACAAGGCCTACCAGTGAATTCTGTGCACCGTATGCACACCGGCCGCGGTAGGGAGCCATATAATATGGTTCTAGTCGCTCTCCAGCCTACCCCGAGGGAGACCCTACTTAAGCCCGCGCGCCGTGACCCTAAAATCGCGAACTATAACATGGTCAGGAACGACAGGCTCTCTGCCCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCGCTCGATCCTCCCGCGCTCGCTAATATCGAAGCATCAGTGTGCCGAATCTCACTGACGGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAGATCGTTCTAAGCAGTGATATCGAGGCGCTGCTCGGTATGGGGAGCTCTGTCATTCTGGCGGGCGACCTAAATTGTAAACACATCAGGTGGAACTCACACACCACAACCCCGAATGGCAGGCGGCTTGACGCGTTAGTCGATGATCTCGCCTTCGATATCGTCGCTCCGCTAACCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCTGCGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTTCCGTTTAGTCCGGACTCTATCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCGTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAGCAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGCCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATCCGTGCGTACGATAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCTCGTAGGCCCCTCAGGCCGACTCGCGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCCTCTGATGCGTTACCACCCGTCACCCCGATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCCAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTTATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTCAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGATATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGTTAGCTGTCGGGGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCAATTCGGAAATACATGAAGTCAGCGTCGGAACGATACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTTGCCGCCGCTGACTACTCCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTTGCATTAGATGCCTTCAGCTCTAATACTAGGGGCAGGCTTAGGGACCCCGGTAACCGTACTCGTCGAACTCGACAAAGAGGTCGACGTGCAACCTAA

Protein

MDAVFAEFLRLRHPQLASEFLAFKANHTASPLEDSAALAAPASPVPACRASALSTAASVVPAAPVSPILARKAAASSAVTIVSAERSSAASVAPSKTPTLARRSPAPASSCSDSDSDMEVDLAPASSTDGFTLVQKGKKRAAESRAPAAAKISKAVNASRPRPQTPVAPPARATPSPRPVAQNKTQTPPPVILQEKAAWDRVCLALKAKNINFTNARNLANGIQIKVQTPDDHRALSSYLRKERISFHTYTLQEERELRVVIRGIPKELDVELVKADLLEQGLPVNSVHRMHTGRGREPYNMVLVALQPTPRETLLKPARRDPKIANYNMVRNDRLSARGGGTVIYYRRALHCVPLDPPALANIEASVCRISLTGHAPIVIASVYLPPDKIVLSSDIEALLGMGSSVILAGDLNCKHIRWNSHTTTPNGRRLDALVDDLAFDIVAPLTPTHYPLNIAHRPDILDIALLKNVTLRLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFSPDSIPSPQDTAEAIDIVTSHITSTLDRSSKQVVAEDFLHRFKLPDDIRELLRAKNASIRAYDSSYSQIGYGSNYAPLVGPSGRLAAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRASLPPSDALPPVTPMEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFRQPIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKYMKSASERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSSNTRGRLRDPGNRTRRTRQRGRRAT

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.
Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon X-element

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A2S2PPK8   X1WNI2   A0A2S2QEE0   J9LC21   A0A023EZE6   A0A224XB44   X1WZH0   K7IN67   A0A2J7R7D0   A0A2S2Q383   A0A224X6Q4   A0A224XI99   A0A224X6S1   A0A2H8TF37   A0A224X6U5   A0A2S2PJG2   J9LFC9   Q9NBX4   A0A224XJI0   A0A2M4BD67   A0A2M4BDV6   A0A2M4CV52   A0A2M4CV42   A0A224X6W2   A0A224X746   A0A2S2N6Q7   A0A1Y1KFR3   A0A087UGF5   A0A224XIB0   A0A2H8TKI9   A0A0V0G5B6   A0A069DZL8   A0A2M4BD66   A0A2S2P7B2   A0A2M4BDA5   A0A2S2PHL7   A0A2M4BD62   A0A069DX78   A0A2M4BD83   A0A2S2P6S3   A0A224X6R6   A0A2S2P3X8   Q07995   P21328   A0A023F0I3   A0A2S2P698   A0A224X724   Q8T9X4   Q8I7P8   A0A224XHW8  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    25474469    20075255    + More
11405632    26334808    8387152    2463954    3040362    1714378   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    GGMR01018716    MBY31335.1    ABLF02008153    ABLF02008462    ABLF02008464    GGMS01006359    MBY75562.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GBBI01004571    JAC14141.1    GFTR01008262    JAW08164.1    ABLF02034467    NEVH01006736    PNF36716.1    GGMS01002992    MBY72195.1    GFTR01008279    JAW08147.1    GFTR01008256    JAW08170.1    GFTR01008271    JAW08155.1    GFXV01000908    MBW12713.1    GFTR01008251    JAW08175.1    GGMR01016905    MBY29524.1    ABLF02023911    AF237761    AAF81411.1    GFTR01008257    JAW08169.1    GGFJ01001858    MBW50999.1    GGFJ01001857    MBW50998.1    GGFL01004957    MBW69135.1    GGFL01005012    MBW69190.1    GFTR01008260    JAW08166.1    GFTR01008151    JAW08275.1    GGMR01000226    MBY12845.1    GEZM01084969    JAV60363.1    KK119692    KFM76444.1    GFTR01008246    JAW08180.1    GFXV01002840    MBW14645.1    GECL01003538    JAP02586.1    GBGD01000415    JAC88474.1    GGFJ01001844    MBW50985.1    GGMR01012676    MBY25295.1    GGFJ01001842    MBW50983.1    GGMR01016296    MBY28915.1    GGFJ01001843    MBW50984.1    GBGD01000389    JAC88500.1    GGFJ01001822    MBW50963.1    GGMR01012443    MBY25062.1    GFTR01008269    JAW08157.1    GGMR01011511    MBY24130.1    S59870    AAB26437.2    M22874    M38643    GBBI01003747    JAC14965.1    GGMR01012305    MBY24924.1    GFTR01008169    JAW08257.1    AF456125    AAL57609.1    AY180919    AAN87272.1    GFTR01008254    JAW08172.1   

Proteomes

UP000053268    UP000007819    UP000002358    UP000235965    UP000054359   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q9NBX4    P21328    Q8T9X4    + More
Q8I7P8   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A2S2PPK8   X1WNI2   A0A2S2QEE0   J9LC21   A0A023EZE6   A0A224XB44   X1WZH0   K7IN67   A0A2J7R7D0   A0A2S2Q383   A0A224X6Q4   A0A224XI99   A0A224X6S1   A0A2H8TF37   A0A224X6U5   A0A2S2PJG2   J9LFC9   Q9NBX4   A0A224XJI0   A0A2M4BD67   A0A2M4BDV6   A0A2M4CV52   A0A2M4CV42   A0A224X6W2   A0A224X746   A0A2S2N6Q7   A0A1Y1KFR3   A0A087UGF5   A0A224XIB0   A0A2H8TKI9   A0A0V0G5B6   A0A069DZL8   A0A2M4BD66   A0A2S2P7B2   A0A2M4BDA5   A0A2S2PHL7   A0A2M4BD62   A0A069DX78   A0A2M4BD83   A0A2S2P6S3   A0A224X6R6   A0A2S2P3X8   Q07995   P21328   A0A023F0I3   A0A2S2P698   A0A224X724   Q8T9X4   Q8I7P8   A0A224XHW8  

KEGG

105841788    no KO assigned | (RefSeq) predicted GPI-anchored protein 58

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

1181

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.13632

Exp number, first 60 AAs:

0.00073

Total prob of N-in:

0.00015

outside

1  -  1181

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

128.708007

CSRT

0

Interpretation

Uncertain