Gene

KWMTBOMO10822  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008445

Annotation

PREDICTED:_xanthine_dehydrogenase/oxidase-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr18(+):3745775-3753032      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.559 PlasmaMembrane   Reliability : 1.109

CDS

ATGTTAAGTATCTGCCCTACCACCTCTACAGAGCCTATTTATAGATCTGGAGCGAATATATTCACAAGGCCAGTATCCGAAGCAACACAAGACTATGTGACTGATTCCTCTTTGTATCCCTTGAATCAACCTGTTCCTAAATTAGAAGCATTGATACAATGTTCTGGAGAAGCTCGATATGCCAATGACCTTCCTCCGCAGAAGAGCGATGTTTTCGGAGCTTTTGTGCTTTCCACCGTCCACAGTGGAGAAGTTGATAAAATTTATGAAAACGAAATCTTGGAAATAGAAGGAGTGCTAGCAATTTACACAGCTAAAGATATTCCAGGTGAGAATACGTTCATAACGCCCGGATTACAGCTTCAAACCGAAAAAGAAGAGACGCTAGCGACTACTATCAAATACTTTGGACAGCCCATAGCTATAGTTGTGGCTCAAACCGAGGAACTGGCGGCTGCGGTAGCGAAAAAAGTACGCGTCGATTACAAAAATACAAAAAAATCAGCTCCCGTTATTACCATAGATGAAGCTAAGAAAGACAGTTCAAGATATATAGCAGGAGAAGGAACTTTGGAGCCAACAAGCAAAGGCACGGATGTAACGAAAATCATAAAGGGAGTGTATGAAATCGAAGCTCAATATCATTACTATATGGAGCCGCTAACGTGTGTGGTTCAACCTGTTGACGATATGTTTATGGTATATGATTCGACGCAGTGGATGGAAATGACTCAAACGGCCATAGCCCGATGTTTGAATATTGGTCAAAGCAAAATTGTAGTAAAAGTTCCAAGAGTAGGGGGTGCGTTCGGCGGTAAAATTACTAGGAACGGTCAAGTGGCAGCCGCGTGTGCGTTGGTAGCGTCCAAACAAAACCGGACTTGTCGATTCATATTGCCTCTACAAACTAATATGAGTATTGCAGGAAAGAGATTGCCTTGCCAATGCGAATATGAGGTAGGAGTGAATGACGACGGCAAGATTCAATATCTCAACGCTACTATAGTTGAGGATGCAGGATGCTGTAACAACGACAATGTCACATCTTACACAAGCTCTAGTTTTGGCAACTGTTACGATATATCGGGTTATACCCTGAATACCGCTACAGTACTTACTGATTTGCCATCAAATACTTTCTTTAGGGCACCCGGTGCTTGCGAAGGAATCGCCTGCATAGAACACATAATGGAGCACATAGCGTTTGCGGTTAAAAAAGATGCAATCTCAGTTCGTCTAGCTAACATGAAAGCAAATAACACTGACATTCCAGAAATGATAGAAACTTTGAAACAAGATGTTGATTATGATAAACGTTGTGCCGACATCCAGCAATTCAATAAAGACAATCGCTGGGTCAAGCGTGCTATAAAGATCAACGTGATGGAATTCCCTGTAATCTATTACGGAAATTTTACTGTAATGATCTCTATTTATCGCATGGACGGAACAGTTACGATAACGACAGGAGGAATAGAAATGGGTCAAGGGGCAAATACGAAGGCCGCCCAAGTTTGCGCCAACGCCTTAGGTATTCCTTTGGACGTTATCAAAGTTATCTCGCACTACTCATTCGTTGCTGCGAATGATGTTTTCTCTGGATCGAGTATCACAACAGAAAGCATTTGCTACTGCATTTTAAAGATATGCGAAACGTTTGATAAAAGATTTGCTCCAGTTAAGTCGCGCAAGCCACAAGCCACTTGGTTGGATATCGTGAAATCAGCTGCTGAAGAAGGAATAGAATTGACGTCCTGCTATATGATGAGCGATAAGGATGAATCTCTTAGTGGATACAGTGCGTTTGCTGTATCGATTGTCGAAATACAGTTGGACGTGTTGACGGGGAGGTTTCAAATGTTGAGAGTAGATTTATTGGAGGATGTTGGAATGAGTGTGAATCCTGCTGTTGACATCGGTCAGGTCGAAGGAGCCTTCATTCAAGGTGTGGGATACTTCACGTGCGAAAAGCTAGTGTATGACAAGGCAACAGGCAAACTACTGACGAATAGATCGCTGACGTACCACGTTCCTCTCTGCCAGGACATACCGATCGTTTATAATGTGAAACTGAGACACAACCAGAAAAATACAAAGGGTGTATTGGGAGCTAAAACATGTGGAGAAATGGGTATATGTACTGCTCACGGTATAACCCTGGCGCTCCGAGAATGCATCATGGCATCTAGAATCGATTCTGGTTACGATTCAACCCAATGGATTACAATCCCTGTCCCTTATGACACAGAAGCAATATTAAAGGCCTTGGATGTGAAGTTAGAAGAGTTTGTCTTCACCACCTCTGACTAG

Protein

MLSICPTTSTEPIYRSGANIFTRPVSEATQDYVTDSSLYPLNQPVPKLEALIQCSGEARYANDLPPQKSDVFGAFVLSTVHSGEVDKIYENEILEIEGVLAIYTAKDIPGENTFITPGLQLQTEKEETLATTIKYFGQPIAIVVAQTEELAAAVAKKVRVDYKNTKKSAPVITIDEAKKDSSRYIAGEGTLEPTSKGTDVTKIIKGVYEIEAQYHYYMEPLTCVVQPVDDMFMVYDSTQWMEMTQTAIARCLNIGQSKIVVKVPRVGGAFGGKITRNGQVAAACALVASKQNRTCRFILPLQTNMSIAGKRLPCQCEYEVGVNDDGKIQYLNATIVEDAGCCNNDNVTSYTSSSFGNCYDISGYTLNTATVLTDLPSNTFFRAPGACEGIACIEHIMEHIAFAVKKDAISVRLANMKANNTDIPEMIETLKQDVDYDKRCADIQQFNKDNRWVKRAIKINVMEFPVIYYGNFTVMISIYRMDGTVTITTGGIEMGQGANTKAAQVCANALGIPLDVIKVISHYSFVAANDVFSGSSITTESICYCILKICETFDKRFAPVKSRKPQATWLDIVKSAAEEGIELTSCYMMSDKDESLSGYSAFAVSIVEIQLDVLTGRFQMLRVDLLEDVGMSVNPAVDIGQVEGAFIQGVGYFTCEKLVYDKATGKLLTNRSLTYHVPLCQDIPIVYNVKLRHNQKNTKGVLGAKTCGEMGICTAHGITLALRECIMASRIDSGYDSTQWITIPVPYDTEAILKALDVKLEEFVFTTSD

Cofactor

FAD
Mo-molybdopterin
[2Fe-2S] cluster

Uniprot

A0A1U9X1S0   H9JFZ8   A0A076FRM9   A0A2A4KA50   A0A0F7QIE0   A0A2H1WDE7   + More
A0A0H4TY60   A0A194QMP0   A0A2H1VIZ6   S5FPI8   A0A1L8D6P5   A0A1L8D6Y2   A0A212F2C6   A0A194PCA1   A0A076FRA1   H9JFZ2   A0A076FX80   A0A194PDZ5   A0A3S2NMY0   A8TUC0   A0A0F7QJV6   A0A2A4JY06   A0A2H1VCW8   A0A2H1VSX5   A0A212FKB8   A0A2A4JYR8   A0A2A4JXM9   A0A1X9ZM23   A8TUB4   A0A2H1VH28   A0A2A4JX39   A0A0H4TD12   A0A2A4JB30   A0A0F7QEA1   A0A0F7QEA3   A0A1X9ZLZ6   A0A194QBY5   H9JFX1   A0A194QCB6   A0A0N0PF58   A0A1B6E3D0   A0A194PIN2   H9JFX4   E2BEN6   A0A2A4ITG3   A0A194QUG5   A0A023F0C3   A0A2H1VUX4   A0A0V0G7W2   A0A3S2PBH0   A0A154PJ92   A0A2W1BG03   A0A2H1VA49   A0A0L7R0P8   A0A0F7QJW1   A0A1X9ZM11   B0X3W4   A0A1B6JH49   A0A2A3E4V2   V9IH93   A0A087ZYD0   A0A2H1V2I4   T1HWZ8   T1I1X5   A0A194PE80   E2ANE4   A0A0N0BES0   A0A194PIT3   A0A2A4JU78   A0A2R7W7R4   A0A2H1VEC0   A0A2A4JUF7   A0A2H1VNQ0   A0A0N0PD45   T1HPX4   A0A195FSQ5   A0A146L5G6   A0A146MB53   A0A151X3M2   A0A0A9YHM8   A0A2W1BJJ3   A0A0N1IAK3   A0A2A4ITB4   F4WWU5   A0A195CSI2   A0A0L7L580   H9JFH1   A0A194PCQ5   A0A2H1VA65   A0A195E465   A0A2J7R4N3   A0A2H1V7P8   A0A194PDB3   A0A310SF38   A0A151X416   A0A034WHE9   A0A0K8UHH7   A0A0K8S633   A0A2W1BIE3   A0A2W1BIK1  

Pubmed

19121390    24817326    25803580    26778204    26354079    23826341    + More
22118469    17904312    20798317    25474469    28756777    26823975    25401762    21719571    26227816    25348373   

EMBL

KY643683    AQY62686.1    BABH01001678    BABH01001679    KF960796    AII21998.1    + More
NWSH01000022    PCG80663.1    LC017754    BAR64768.1    ODYU01007852    SOQ50986.1    KP899547    AKQ06146.1    KQ461196    KPJ06614.1    ODYU01002835    SOQ40809.1    KC952900    AGQ43599.1    GEYN01000003    JAV02126.1    GEYN01000002    JAV02127.1    AGBW02010767    OWR47879.1    KQ459606    KPI90901.1    KF960795    AII21997.1    BABH01001657    BABH01001658    BABH01001659    BABH01001660    KF960794    AII21996.1    KPI90909.1    RSAL01000229    RVE43893.1    EU073424    ABW71272.1    LC017753    BAR64767.1    NWSH01000413    PCG76558.1    ODYU01001878    SOQ38698.1    ODYU01004253    SOQ43930.1    AGBW02008082    OWR54176.1    PCG76560.1    PCG76559.1    KY595779    ARS46833.1    EU073423    ABW71271.1    ODYU01002537    SOQ40155.1    PCG76561.1    KP899546    AKQ06145.1    NWSH01002143    PCG69059.1    LC017752    BAR64766.1    LC017757    BAR64771.1    KY595778    ARS46832.1    KQ459193    KPJ03063.1    BABH01001558    KPJ03064.1    KQ459674    KPJ20482.1    GEDC01004862    JAS32436.1    KPI90950.1    BABH01001568    BABH01001569    BABH01001570    BABH01001571    BABH01001572    BABH01001573    GL447829    EFN85870.1    NWSH01007172    PCG63055.1    KQ461154    KPJ08620.1    GBBI01004413    JAC14299.1    ODYU01004588    SOQ44620.1    GECL01002669    JAP03455.1    RSAL01000123    RVE46648.1    KQ434912    KZC11368.1    KZ150165    PZC72655.1    ODYU01001472    SOQ37709.1    KQ414670    KOC64413.1    LC017758    BAR64772.1    KY595781    ARS46835.1    DS232324    EDS40041.1    GECU01009219    JAS98487.1    KZ288369    PBC26783.1    JR045677    AEY60027.1    ODYU01000376    SOQ35055.1    ACPB03000354    ACPB03000355    ACPB03005165    KPI90999.1    GL441193    EFN65044.1    KQ435826    KOX72014.1    KPI91000.1    NWSH01000648    PCG75033.1    KK854425    PTY15753.1    ODYU01002094    SOQ39169.1    PCG75032.1    ODYU01003306    SOQ41884.1    KQ460326    KPJ15694.1    ACPB03021369    ACPB03021370    KQ981281    KYN43332.1    GDHC01015520    JAQ03109.1    GDHC01013650    GDHC01001960    JAQ04979.1    JAQ16669.1    KQ982557    KYQ55015.1    GBHO01014557    GBHO01014554    GBRD01002756    JAG29047.1    JAG29050.1    JAG63065.1    KZ150135    PZC72996.1    KPJ15693.1    NWSH01007964    PCG62736.1    GL888413    EGI61333.1    KQ977306    KYN03668.1    JTDY01002917    KOB70491.1    BABH01034958    BABH01034959    BABH01034960    BABH01034961    BABH01034962    BABH01034963    BABH01034964    BABH01034965    KPI90997.1    ODYU01001481    SOQ37735.1    KQ979701    KYN19697.1    NEVH01007404    PNF35793.1    ODYU01001109    SOQ36868.1    KPI90998.1    KQ769812    OAD52839.1    KYQ55014.1    GAKP01005225    JAC53727.1    GDHF01026190    JAI26124.1    GBRD01017213    JAG48614.1    PZC72997.1    PZC72656.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000007151    UP000053268    UP000283053    + More
UP000008237    UP000076502    UP000053825    UP000002320    UP000242457    UP000005203    UP000015103    UP000000311    UP000053105    UP000078541    UP000075809    UP000007755    UP000078542    UP000037510    UP000078492    UP000235965   

PRIDE

H9JFZ8    H9JFZ2    A8TUC0    A8TUB4    H9JFX1    H9JFX4    + More
H9JFH1   

Pfam

PF02738   Ald_Xan_dh_C2        + More
PF03450   CO_deh_flav_C
PF01315   Ald_Xan_dh_C
PF01799   Fer2_2
PF00941   FAD_binding_5
PF00111   Fer2
PF01130   CD36
PF07651   ANTH

Interpro

IPR002888   2Fe-2S-bd        + More
IPR016208   Ald_Oxase/xanthine_DH       
IPR000674   Ald_Oxase/Xan_DH_a/b       
IPR036318   FAD-bd_PCMH-like_sf       
IPR036884   2Fe-2S-bd_dom_sf       
IPR005107   CO_DH_flav_C       
IPR008274   AldOxase/xan_DH_Mopterin-bd       
IPR001041   2Fe-2S_ferredoxin-type       
IPR036010   2Fe-2S_ferredoxin-like_sf       
IPR036683   CO_DH_flav_C_dom_sf       
IPR006058   2Fe2S_fd_BS       
IPR016166   FAD-bd_PCMH       
IPR002346   Mopterin_DH_FAD-bd       
IPR037165   AldOxase/xan_DH_Mopterin-bd_sf       
IPR036856   Ald_Oxase/Xan_DH_a/b_sf       
IPR012675   Beta-grasp_dom_sf       
IPR016169   FAD-bd_PCMH_sub2       
IPR002159   CD36_fam       
IPR013809   ENTH       
IPR008942   ENTH_VHS       
IPR011417   ANTH_dom       
IPR014712   Clathrin_AP_dom2       

SUPFAM

SSF47741   SSF47741        + More
SSF56003   SSF56003       
SSF56176   SSF56176       
SSF55447   SSF55447       
SSF54292   SSF54292       
SSF54665   SSF54665       
SSF48464   SSF48464       

Gene 3D

3.10.20.30     3.30.465.10     1.20.58.150     1.25.40.90    

CDD

cd00207  fer2

ProteinModelPortal

A0A1U9X1S0   H9JFZ8   A0A076FRM9   A0A2A4KA50   A0A0F7QIE0   A0A2H1WDE7   + More
A0A0H4TY60   A0A194QMP0   A0A2H1VIZ6   S5FPI8   A0A1L8D6P5   A0A1L8D6Y2   A0A212F2C6   A0A194PCA1   A0A076FRA1   H9JFZ2   A0A076FX80   A0A194PDZ5   A0A3S2NMY0   A8TUC0   A0A0F7QJV6   A0A2A4JY06   A0A2H1VCW8   A0A2H1VSX5   A0A212FKB8   A0A2A4JYR8   A0A2A4JXM9   A0A1X9ZM23   A8TUB4   A0A2H1VH28   A0A2A4JX39   A0A0H4TD12   A0A2A4JB30   A0A0F7QEA1   A0A0F7QEA3   A0A1X9ZLZ6   A0A194QBY5   H9JFX1   A0A194QCB6   A0A0N0PF58   A0A1B6E3D0   A0A194PIN2   H9JFX4   E2BEN6   A0A2A4ITG3   A0A194QUG5   A0A023F0C3   A0A2H1VUX4   A0A0V0G7W2   A0A3S2PBH0   A0A154PJ92   A0A2W1BG03   A0A2H1VA49   A0A0L7R0P8   A0A0F7QJW1   A0A1X9ZM11   B0X3W4   A0A1B6JH49   A0A2A3E4V2   V9IH93   A0A087ZYD0   A0A2H1V2I4   T1HWZ8   T1I1X5   A0A194PE80   E2ANE4   A0A0N0BES0   A0A194PIT3   A0A2A4JU78   A0A2R7W7R4   A0A2H1VEC0   A0A2A4JUF7   A0A2H1VNQ0   A0A0N0PD45   T1HPX4   A0A195FSQ5   A0A146L5G6   A0A146MB53   A0A151X3M2   A0A0A9YHM8   A0A2W1BJJ3   A0A0N1IAK3   A0A2A4ITB4   F4WWU5   A0A195CSI2   A0A0L7L580   H9JFH1   A0A194PCQ5   A0A2H1VA65   A0A195E465   A0A2J7R4N3   A0A2H1V7P8   A0A194PDB3   A0A310SF38   A0A151X416   A0A034WHE9   A0A0K8UHH7   A0A0K8S633   A0A2W1BIE3   A0A2W1BIK1  

PDB

5EPG     E-value=6.23892e-85,     Score=803

KEGG

101741112    K00106 xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] | (RefSeq) xanthine dehydrogenase/oxida

PATHWAY

00230    Purine metabolism - Bombyx mori (domestic silkworm)
00232    Caffeine metabolism - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0102797   GO:0009055   GO:0004031   GO:0071949   GO:0102798   GO:0005506   GO:0051537   GO:0050660   GO:0016491   GO:0046872   GO:0016021   GO:0030276   GO:0048268   GO:0030136   GO:0005545   GO:0016614   GO:0009374   GO:0003677   GO:0004075   GO:0003824   GO:0055114  

Length:

769

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.24828

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00536

outside

1  -  769

 

 

Pi

192.867026

Theta

164.36581

Tajima's D

0.446938

CLR

0.112314

CSRT

0.494075296235188

Interpretation

Uncertain