Gene

KWMTBOMO10812

Pre Gene Modal

BGIBMGA000215

Annotation

sensory_neuron_membrane_protein_1_[Bombyx_mori]

Location

Bomo_Chr18(+):3562843-3568236      View in EpiBrowser

Full name

Sensory neuron membrane protein 1      

Alternative Name

Scavenger receptor class B

Location in the cell

Cytoplasmic   Reliability : 2.977

CDS

ATGGATTACTATCGTAACAATTCGGTGGACCCTCACGTTGTGACAGTCAAACGTGGAGTCCAAAACGTTATGGACGTCGGTCGAGTCGTAGCGATAGACGGGAAAACCAAAATGAACGTTTGGAGGGACTCTTGTAACGAGTACCAAGGAACGGATGGCACCGTTTTCCCGCCATTCCTGACGCACAAAGATCGCCTGCAGTCATTTTCCGGGGATTTGTGCAGGTCATTCAAACCGTGGTTTCAAAAAAAGACATCGTACAATGGGATTAAGACGAATCGCTATGTCGCCAACATTGGTGATTTTGCCAACGATCCAGAATTACAGTGCTACTGTGACAGCCCTGACAAATGCCCCCCAAAAGGCCTGATGGACTTGTACAAGTGCATCAAAGCTCCAATGTTTGTCTCCATGCCTCATTACTTGGAGGGAGACCCGGAACTGTTGAAGAACGTGAAAGGATTGAATCCTAATGCTAAGGACCATGGAATCGAAATCGATTTTGAACCGATCAGTGGTACGCCGATGGTTGCTAAGCAACGCATTCAGTTCAACATACAGCTGCTGAAATCAGAAAAAATGGAATTACTCAAAGATCTTCCTGGAACTATTGTTCCTTTATTATGGATTGAAGAAGGTTTGTCATTGAACAAGACATTCGTGAAAATGCTTAAAAGTCAGCTGTTTATACCGAAGCGTGTTGTCTCCGTGGTTTGCTGGTGTATGATATCTTTTGGCTCTGTTGGGGTCATAGCCGCAATGATATTCCATTTCAAAGGTGATATAATGCACTTGGCTGTGGCAGGAGACAACTCAGTTTCCAAAATAAAACCTGAAAACGAAGAAAATAAAGAAGTGGGCGTTATGGGCCAGAATCAAGAACCAGCCAAAGTGATGTAA

Protein

MDYYRNNSVDPHVVTVKRGVQNVMDVGRVVAIDGKTKMNVWRDSCNEYQGTDGTVFPPFLTHKDRLQSFSGDLCRSFKPWFQKKTSYNGIKTNRYVANIGDFANDPELQCYCDSPDKCPPKGLMDLYKCIKAPMFVSMPHYLEGDPELLKNVKGLNPNAKDHGIEIDFEPISGTPMVAKQRIQFNIQLLKSEKMELLKDLPGTIVPLLWIEEGLSLNKTFVKMLKSQLFIPKRVVSVVCWCMISFGSVGVIAAMIFHFKGDIMHLAVAGDNSVSKIKPENEENKEVGVMGQNQEPAKVM

Description

Plays an olfactory role that is not restricted to pheromone sensitivity.
Plays an olfactory role that is not restricted to pheromone sensitivity. May be involved in the odor detection properties of the olfactory receptor neurons (ORNs) rather than their differentiation and growth.
Plays an olfactory role that is not restricted to pheromone sensitivity. Has a role in detection and signal transduction of the fatty-acid-derived male pheromone 11-cis vaccenyl acetate (cVA). Not required for sensitivity to general odorants. Acts in concert with Or67d and lush to capture cVA molecules on the surface of Or67d expressing olfactory dendrites and facilitate their transfer to the odorant-receptor Orco complex. Essential for the electrophysiological responses of these olfactory sensory neurons (OSNs) to cVA. Not required for the development of trichoid OSNs and support cells.

Similarity

Belongs to the CD36 family.

Keywords

Cell membrane   Complete proteome   Disulfide bond   Glycoprotein   Membrane   Olfaction   Receptor   Reference proteome   Sensory transduction   Transmembrane   Transmembrane helix   Pheromone   Polymorphism   Direct protein sequencing  

Feature

chain  Sensory neuron membrane protein 1

Uniprot

H9ISI8   Q9U3U2   B2LT48   Q8I9S1   A0A076EDK4   Q9U1G3   + More
A0A1V1WC00   U3LWW8   E5EZW6   A0A0F7QEJ4   E5EZW7   Q8I9S2   Q9GPH7   V9NDY0   A0A2H4FY01   A0A0K8TUR2   A0A076E7R0   A0A2K8GL00   M1NR22   E2IHA6   H9XFD6   A0A2A4JY06   A0A194QM75   A0A1B3P5M0   O02351   A0A0H4CUW6   A0A194PDZ5   J9Z4W3   A0A290U4J3   A0A3Q8HNU5   D0EAE2   A0A3G6VEY0   A0A212FKA7   A4UVN4   A0A0L7LIF1   W8BIS1   W8BUC5   W8BDX2   A0A034VUU2   G0YYB1   A0A0K8V8V4   A0A1W4VKX8   A0A1I8PEF0   A0A0G2UGL0   A0A3B0K2D5   A0A0A1XSX8   B4R136   A0A0B4KGL9   Q9VDD3   B3P048   B4IKJ4   A0A1J0KKG7   A0A0C5DMP8   Q295A8   A0A1I8MM91   A0A3B0K518   T1PAF9   B4PQC2   B4GMC9   A0A1P8P1N7   A0A1J0KKP5   A0A097PUI9   L7X034   A0A0L7QP07   A0A182R9Z3   P86905   A0A182SLS4   B3MTS2   B0X4H7   A0A1S4K2Y0   B4KB36   A0A139WJH8   A0A182NFI4   B0X4H5   G0YYB0   A0A182VXB8   G0YYB2   A0A182MFA2   M4W9B3   T1IC87   W8C9T0   D2A0H5   A0A084WRH6   A0A0G2UET8   A0A1I8MBE2   A0A2A3E5X6   B4NK88   A0A1I9HZQ1   B0X4H6   A0A0L0BW98   A0A182PZG9   A0A3Q9ELV0   A0A068FBS5   A0A310SBT1   Q7QC49   B4JG39   A0A1Y1M4I8   A0A2H4ZBG9   B4LYC5   A0A182K9P0  

Pubmed

19121390    11536197    24998398    18209018    21056664    25803580    + More
24436214    26017144    28736530    23454276    23027616    26354079    27538507    9169446    11320659    30474190    19789654    30465940    22118469    26227816    24495485    25348373    21504749    25830018    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    19364529    17943085    18653762    21948708    27836740    25665775    15632085    25315136    18342246    18362917    19820115    23517120    24438588    24893337    26108605    30542294    25880816    12364791    28004739    29133804   

EMBL

BABH01042459    BABH01042460    AJ251958    CAB65730.1    EU580138    ACC61201.1    + More
AF462067    AAO15604.1    KF487732    AII01130.1    AJ251959    CAB65739.1    GENK01000127    JAV45786.1    KC571258    AGN48098.1    HM044389    HM044388    ADQ73892.1    ADQ73893.1    LC017801    BAR64815.1    HM044390    ADQ73894.1    AF462066    AAO15603.1    AF323589    AAG49366.1    JX469106    AGN52676.1    KY130486    APG32554.1    GCVX01000224    JAI18006.1    KF487734    AII01132.1    KX585410    ARO70303.1    KC182740    AGF87119.1    HM536984    ADK66278.1    JN867063    AFG73002.1    NWSH01000413    PCG76558.1    KQ461196    KPJ06622.1    KX655935    AOG12884.1    U95026    AAC47540.1    KP684218    MH598590    AKN78948.1    AZB86632.1    KQ459606    KPI90909.1    JX401524    AFS50073.1    KX954369    ATD12153.1    GQ451327    ACX47899.1    MH178116    AZB52756.1    AGBW02008082    OWR54175.1    AB026557    BAF57237.1    JTDY01000994    KOB75165.1    GAMC01009642    JAB96913.1    GAMC01009644    JAB96911.1    GAMC01009643    JAB96912.1    GAKP01011851    JAC47101.1    HQ845070    AEK32387.1    GDHF01017033    JAI35281.1    KP743734    AKI29050.1    OUUW01000014    SPP88394.1    GBXI01000272    JAD14020.1    CM000364    EDX12123.1    AE014297    AGB96183.1    BT024286    EF560170    EF560171    EF596938    AAF55863.2    ABC86348.1    ABQ42604.1    ABQ42605.1    ABQ96635.1    CH954181    EDV48284.1    CH480853    EDW51598.1    KX290651    APC94222.1    KP296781    AJO62245.1    CM000070    EAL28804.2    SPP88393.1    KA644913    AFP59542.1    CM000160    EDW96231.1    CH479185    EDW38003.1    KU315195    APX56328.1    KX298786    APC94303.1    KM245938    AIU56857.1    KC012595    AGC91908.1    KQ414843    KOC60350.1    AADG06001198    CH902623    EDV30203.1    DS232341    EDS40330.1    CH933806    EDW15740.1    KQ971338    KYB28031.1    EDS40328.1    HQ845069    AEK32386.1    HQ845071    AEK32388.1    AXCM01007870    KC113423    AGI05171.1    ACPB03017884    GAMC01001889    JAC04667.1    CM000279    EFA02899.1    ATLV01026062    KE525405    KFB52820.1    KP743735    AKI29051.1    KZ288377    PBC26646.1    CH964272    EDW85130.1    KJ027554    AIX97076.1    EDS40329.1    JRES01001243    KNC24302.1    AXCN02000212    MK049038    AZQ24979.1    KJ702172    AID61326.1    GGOB01000131    MCH29527.1    AAAB01008859    CH916369    EDV93606.1    GEZM01040787    JAV80739.1    MF975517    AUF73093.1    CH940650    EDW66921.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000037510    + More
UP000192221    UP000095300    UP000268350    UP000000304    UP000000803    UP000008711    UP000001292    UP000001819    UP000095301    UP000002282    UP000008744    UP000053825    UP000075900    UP000005203    UP000075901    UP000007801    UP000002320    UP000009192    UP000007266    UP000075884    UP000075920    UP000075883    UP000015103    UP000030765    UP000242457    UP000007798    UP000037069    UP000075886    UP000007062    UP000001070    UP000008792    UP000075881   

PRIDE

H9ISI8    Q9U3U2    B2LT48    Q9U1G3    E5EZW6    E5EZW7    + More
Q9GPH7    Q9VDD3    P86905    B0X4H5    D2A0H5   

Pfam

PF01130   CD36        + More
PF01799   Fer2_2
PF00941   FAD_binding_5
PF03450   CO_deh_flav_C
PF00111   Fer2
PF01315   Ald_Xan_dh_C
PF02738   Ald_Xan_dh_C2

Interpro

IPR002159   CD36_fam        + More
IPR036010   2Fe-2S_ferredoxin-like_sf       
IPR001041   2Fe-2S_ferredoxin-type       
IPR036683   CO_DH_flav_C_dom_sf       
IPR036856   Ald_Oxase/Xan_DH_a/b_sf       
IPR006058   2Fe2S_fd_BS       
IPR037165   AldOxase/xan_DH_Mopterin-bd_sf       
IPR002346   Mopterin_DH_FAD-bd       
IPR016166   FAD-bd_PCMH       
IPR000674   Ald_Oxase/Xan_DH_a/b       
IPR002888   2Fe-2S-bd       
IPR008274   AldOxase/xan_DH_Mopterin-bd       
IPR005107   CO_DH_flav_C       
IPR036884   2Fe-2S-bd_dom_sf       
IPR036318   FAD-bd_PCMH-like_sf       
IPR005428   CD36/SCARB1/SNMP1       

SUPFAM

SSF55447   SSF55447        + More
SSF56003   SSF56003       
SSF56176   SSF56176       
SSF47741   SSF47741       
SSF54665   SSF54665       
SSF54292   SSF54292       

ProteinModelPortal

H9ISI8   Q9U3U2   B2LT48   Q8I9S1   A0A076EDK4   Q9U1G3   + More
A0A1V1WC00   U3LWW8   E5EZW6   A0A0F7QEJ4   E5EZW7   Q8I9S2   Q9GPH7   V9NDY0   A0A2H4FY01   A0A0K8TUR2   A0A076E7R0   A0A2K8GL00   M1NR22   E2IHA6   H9XFD6   A0A2A4JY06   A0A194QM75   A0A1B3P5M0   O02351   A0A0H4CUW6   A0A194PDZ5   J9Z4W3   A0A290U4J3   A0A3Q8HNU5   D0EAE2   A0A3G6VEY0   A0A212FKA7   A4UVN4   A0A0L7LIF1   W8BIS1   W8BUC5   W8BDX2   A0A034VUU2   G0YYB1   A0A0K8V8V4   A0A1W4VKX8   A0A1I8PEF0   A0A0G2UGL0   A0A3B0K2D5   A0A0A1XSX8   B4R136   A0A0B4KGL9   Q9VDD3   B3P048   B4IKJ4   A0A1J0KKG7   A0A0C5DMP8   Q295A8   A0A1I8MM91   A0A3B0K518   T1PAF9   B4PQC2   B4GMC9   A0A1P8P1N7   A0A1J0KKP5   A0A097PUI9   L7X034   A0A0L7QP07   A0A182R9Z3   P86905   A0A182SLS4   B3MTS2   B0X4H7   A0A1S4K2Y0   B4KB36   A0A139WJH8   A0A182NFI4   B0X4H5   G0YYB0   A0A182VXB8   G0YYB2   A0A182MFA2   M4W9B3   T1IC87   W8C9T0   D2A0H5   A0A084WRH6   A0A0G2UET8   A0A1I8MBE2   A0A2A3E5X6   B4NK88   A0A1I9HZQ1   B0X4H6   A0A0L0BW98   A0A182PZG9   A0A3Q9ELV0   A0A068FBS5   A0A310SBT1   Q7QC49   B4JG39   A0A1Y1M4I8   A0A2H4ZBG9   B4LYC5   A0A182K9P0  

PDB

5LGD     E-value=6.25246e-36,     Score=376

KEGG

692679    no KO assigned | (RefSeq) Snmp1, BmSCRB1, SCRB1, SNMP1-Bmor; sensory neuron membrane protein-1

GO

GO:0016021   GO:0007608   GO:0050896   GO:0005886   GO:0005186   GO:0051537   GO:0046872   GO:0009055   GO:0071949   GO:0005929   GO:0035073   GO:0043025   GO:0019236   GO:0055088   GO:0071444   GO:0007166   GO:0050911   GO:0030425   GO:0016020   GO:0003824   GO:0016614   GO:0050660   GO:0005506  

PANTHER

PTHR11923  

Subcellular location

Cell membrane  

Length:

299

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.95288

Exp number, first 60 AAs:

0.00171

Total prob of N-in:

0.94882

inside

1  -  233

TMhelix

234  -  256

outside

257  -  299

 

 

Pi

217.338905

Theta

188.119354

Tajima's D

0.319129

CLR

0.037446

CSRT

0.456977151142443

Interpretation

Uncertain