Gene

KWMTBOMO10759

Pre Gene Modal

BGIBMGA008421

Annotation

aldehyde_oxidase_AOX1_[Cydia_pomonella]

Location

Bomo_Chr18(+):2517390-2559071      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.451

CDS

ATGGATAAAATTAATTTCACCATCAATGGAGAACAATACAGTTTGTCGGGCGCAGACGTCAGCCCAGTGACGTCACTGAATGACTACATCAGGCATCACCTCCAACTTCATGGTACGAAGGCGATGTGCCACGAGGGCGGCTGTGGGGCATGCGTGGTCTCTGTTCAGCGGACACATCCCACCACCAAAAAGGAGGAAACTCTCGCTGTAAATTCTTGTCTCGTTCACATCCTCTCCTGTCACGAATGGAACATAACGACCGTGGAAGGCGTGGGCAATCGAAGAGACGGCTACCACGCCATACAGGAGCGCCTGGCGATGTTCAACGGGACTCAATGCGGATACTGCACGCCGGGATGGGTCATGAATATGTACAGCTTGTACAAGAGTTCACAGAAAAGCTTAACCACTCAGCAAGTCGAGAATTCATTTGGCAGCAACATATGTCGGTGTACCGGATACAGACCGATTTTGGACGCATTCAAAAGCTTCGCCAACGACACGGAGCCTAGTTCAAAATTACAGGACTTAGAAGATTTACACATAAAGAAATGCATGAATAGTTGTAAACGAAAGTGCAGTATATCGGATGAATGGTGCTTCATAGAGAGACCGTTTCAATCGTTGCTTGAGCTAAGCGTCGCGGGAGGTCGCTGGTACAAAGCTTTTACCGTGCAAGATATATTTAATATTCTGAGGCGTGAAGGAAGTAATAATTACAGACTGGTCGCCGGAAACACGGGGCAAGGAGTTTATCCAATAAAAACGGAGCCAAAGATCTACATAGACATATCGTCGATAGACCGACTGAAGGACGCGCATTCAGACGAGAACTTGAATCTGGGAGCCGGCCTGAGCTTGACCGAAACCATGGATGTCTTTGAAAGGTGGTCTACGAACGAGGAGTACAAATACTTGCTGCAGCTCCGTGAGCATGTGGATTTAGTCGCACACGTGCCTGTACGAAATATCGGCACTCTTGGTGGGAACTTGGCTTTGAAGAACAAGCACAATGAATTCCCTTCAGATATTTTCTTACTGCTGGAAACGATTGGAGCGACTGTCGGAATAATAAAAAGCGATATGAAGATTTCTGATGTGAGCATGTCGCAGTTCCTGAAAATGGATCTCAAAAATAATCTCATAGGCGATGTTAAGCTGCCTCCTTTATCAGCGAATAACCTCTTAAGGACATACAAGATAATGCCGCGAGCCCAGAACGCACACGCCATCGTCAACGCCGGTTTCTTGTTCAAACTGGACCAGGAGAAAAAGGTCGCTGGTTCGAACATAATATACGGAAACATAAGCCCTTCATTCGTTCACGCCACTCAAACGGAGAACAGCTTAATCGGTCTGGAGTTGTTTAAGGACGAGACCTTGTCGAAGGCACTCGAGATACTGGAAAAGGAAATAATTCCTGTTGATTTGCCTCCAGAACCGTCACCGTCCTGTAGGAAGCACCTAGCGCTAGGCTTATTTTATAAGGCCATTCTCTCGTTAGCTCCTGCGGTGAATCCTCGGTACGCGTCAGGCGGGACCACGCTGAAGCGGCTCGTATCGAGGGGAGAGCAGACGTTCGAAACAGATAAATCTTTATGGCCGCTTAACGAGCCAGTGCCGAAACTGGAGGCTCTGACACAGTGCTCCGGTGAGGTGAAGTATGCGTGTGACGTGTACACGGGGCCAAGGACTGTCCATGTCGCCTTCGTGTTATCCGACGTGTGCCTTGGCGAGATTGAAGGCTTCGACGAATCCGAGGCGTTGAAACTCCAAGGCGTGGTCGGATTCTACACCGCCAAAGACATACCCGGCAAGAACGTCTTCACACCGTCAGACGTGCCGTGGCAAGACTTCGCTGAAGAGATCCTGGCTTCGAAGAAAATCTCTTACTACGGGCAGCCCGTCGCTCTCATAGCCGCGACGACACACAGACTAGTGCTCACTGCTGCTAATTTAGTTCGTGTGAAGTACAAGAAATCTAATGCGGTTCCTGTGTTGTCTATTCAAGAAGCATTAGTAGCTGCTGATAAGGAGCAAAGGGTTCGGCAGGAGGTAGCAATCAAAGCGACCAGCAAAGGCTCGGATACCCGACACGTTATAAAGGGTAGTTTCTCGATGCCGTCCCAGTACCACTACACGATGGAGACTCAGTCCTGTACCGTCGCCGTCACGTCGCGCGGGGTGGCCGTGCGCTCCTCCACCCAGTGGATGGACATAGTCCACGTTGCTGTGGCCCAGACACTCGGCATTGATGAAAACAGGGTGGAGGTGTCGGTGCCCCGCGTGGGCGGCGCGTTCGGGGGCAAGGCGTCTCGCGCGGCGCTGGCGGCGTGCGCATGCGCGGTGGTCGCCAGCCGCACGCACCGCGCCGCCTCGCTCGTGATGCCGCTCGGCGACAACATGGCCGCGATCGGGAAGCGTTCGCAATGCGACGCGCGTTACGAGGTCGGCGTGAACGACGAGGGCGTTGTTCAATACGCGAACATCGAATACTACGTGGACTGCGGGTACGCTTACAACGACACTTCCGCCCCGGATGTAGCCTCGATACTGACCAATCTGTACGCGACTGACACTTGGAACATCAACGGATATAGTGTCTTGACGGATAAGCATAGCAACACCTGGTGCAGAGCTCCCGGGACAACGGAAGCCACAGCCATCTTAGAACATTTAATGGAACGAATAGCGCAAGTCACCGGCAAAGATCCTTCCGAAGTCCGAATCTCCAACTTGGCACAGAAACACGAAGCCATCAAGGATATGATCACGGGTTTTAAGCGTGAAGTGGAGTTCGATGACAGAATGGTCCAAATCAAAAAGTTCAATGAGGAGAACGCGTGGCGAAAAAAGGCCTTGAAGCTATCCATCATGTCTTATCCTATAGGCTACTCCTACAACTTCCCCGTTACGATATCAATATACCACGCAGACGGTACTGTGGCCATATCCCACGGGGGTATCGAGATGGGTCAGGGTATCAACACGAAAGTCGCTCAAGTTTGCGCATATAGCTTAAAAATACCCCTAGCTAAGGTCACAGTTAGGGGCAGCAACAGTTTCATCTCACCAAATTCTATGGCTAGCAACGGAAGCATTACTAGTGATTGCGTGGCCTATGCTACTGTGAAGGCTTGTGAGGAGCTGCTGAGCAGGCTACAAGATGCTAAGAAGAATTTGAATGAACCCACTTGGGAGGAAACTATTAAGGCTGCTTATGATAAAGGCGTCAACCTCCAAGCGTCTTATATGACGTCACCCAATGACAATCTAGTGGGCTATGACGTGTACGGAGTCTGCATAGCTGAAGTGGAACTAGACGTGCTGACCGGAAACCACATCCTCACAAGGGTCGATCTGTTGGAAGATACCGGAGTCAGTATTAGTCCTGACATCGACGTGGGACAGATTGAAGGAGCGTTTGTGATGGGTCTCGGTTTGTGGACAACAGAAAGACTGGTCTATGATAAGACAGGGAGACTTCTTACTGACAGGACGTGGACGTACAAGCCCCCGGGTGCTAAGGATATCCCAGTTGACTTCAGGGTTTCGTTCAGGAGAAACGCCCCTAACCCTGCTGGAGTTTTGAGGTCAAAAGCAACCGGTGAACCGGCGTTGGTTTTGGCTGTGGTAGTCATTCACGCATTGCACGAGACCATCGTGGAAGCGAGGAAGGAACACGGGTACCGCGACGTGGAATGGCTACAAGTCGACACACCATACAGCGTGGAGAATATACTAGAAGCGATTTCACCCAGGATAGGAAGCTTTAAATTAACCTGA

Protein

MDKINFTINGEQYSLSGADVSPVTSLNDYIRHHLQLHGTKAMCHEGGCGACVVSVQRTHPTTKKEETLAVNSCLVHILSCHEWNITTVEGVGNRRDGYHAIQERLAMFNGTQCGYCTPGWVMNMYSLYKSSQKSLTTQQVENSFGSNICRCTGYRPILDAFKSFANDTEPSSKLQDLEDLHIKKCMNSCKRKCSISDEWCFIERPFQSLLELSVAGGRWYKAFTVQDIFNILRREGSNNYRLVAGNTGQGVYPIKTEPKIYIDISSIDRLKDAHSDENLNLGAGLSLTETMDVFERWSTNEEYKYLLQLREHVDLVAHVPVRNIGTLGGNLALKNKHNEFPSDIFLLLETIGATVGIIKSDMKISDVSMSQFLKMDLKNNLIGDVKLPPLSANNLLRTYKIMPRAQNAHAIVNAGFLFKLDQEKKVAGSNIIYGNISPSFVHATQTENSLIGLELFKDETLSKALEILEKEIIPVDLPPEPSPSCRKHLALGLFYKAILSLAPAVNPRYASGGTTLKRLVSRGEQTFETDKSLWPLNEPVPKLEALTQCSGEVKYACDVYTGPRTVHVAFVLSDVCLGEIEGFDESEALKLQGVVGFYTAKDIPGKNVFTPSDVPWQDFAEEILASKKISYYGQPVALIAATTHRLVLTAANLVRVKYKKSNAVPVLSIQEALVAADKEQRVRQEVAIKATSKGSDTRHVIKGSFSMPSQYHYTMETQSCTVAVTSRGVAVRSSTQWMDIVHVAVAQTLGIDENRVEVSVPRVGGAFGGKASRAALAACACAVVASRTHRAASLVMPLGDNMAAIGKRSQCDARYEVGVNDEGVVQYANIEYYVDCGYAYNDTSAPDVASILTNLYATDTWNINGYSVLTDKHSNTWCRAPGTTEATAILEHLMERIAQVTGKDPSEVRISNLAQKHEAIKDMITGFKREVEFDDRMVQIKKFNEENAWRKKALKLSIMSYPIGYSYNFPVTISIYHADGTVAISHGGIEMGQGINTKVAQVCAYSLKIPLAKVTVRGSNSFISPNSMASNGSITSDCVAYATVKACEELLSRLQDAKKNLNEPTWEETIKAAYDKGVNLQASYMTSPNDNLVGYDVYGVCIAEVELDVLTGNHILTRVDLLEDTGVSISPDIDVGQIEGAFVMGLGLWTTERLVYDKTGRLLTDRTWTYKPPGAKDIPVDFRVSFRRNAPNPAGVLRSKATGEPALVLAVVVIHALHETIVEARKEHGYRDVEWLQVDTPYSVENILEAISPRIGSFKLT

Cofactor

FAD
Mo-molybdopterin
[2Fe-2S] cluster

Uniprot

H9JFX4   A0A2H1VSX5   A0A0F7QEA3   A0A0H4TD12   A0A2H1VCW8   A0A194PIN2   + More
A0A2A4JB30   A0A0F7QJV6   A0A076FRA1   A0A076FX80   A0A2A4JXM9   A8TUC0   A0A3S2NMY0   A0A2H1VH28   A0A0F7QEA1   A0A212FKB8   A0A1X9ZM23   H9JFZ2   A0A2A4JY06   A8TUB4   A0A2A4JX39   A0A0N1I7K2   A0A1X9ZLZ6   A0A194QBY5   A0A3S2PBH0   A0A151X416   A0A0N0PF58   A0A195E465   F4WWU5   A0A154PJ92   D7EK61   A0A0N0BES0   A0A195E3I3   A0A195FSQ5   A0A151I2B1   A0A0L7R0P8   A0A151X3M2   D7EK62   A0A194PE80   A0A087ZYD0   A0A2A4ITG3   A0A2H1V2I4   A0A2A3E4V2   V9IH93   A0A2A4JU78   E2ANE4   A0A195CT20   A0A1X9ZM11   A0A1B6E3D0   S5FPI8   A0A195CSI2   A0A0F7QIE0   A0A310SF38   A0A023F0C3   A0A194QMP0   A0A0K1YW91   A0A182QVB6   A0A2A4JUF7   D6W6X3   A0A2A4IRV9   A0A0K1YWY0   A0A2A4ITB4   B0X3W2   A0A2W1BJJ3   A0A336MA50   A0A1Q3FSG4   B0X3W4   A0A1Q3FGZ2   A0A076FRM9   A0A1Q3FG61   W5JEG5   A0A084WK44   A0A194PCQ5   A0A2M3ZFL0   A0A182VKT2   A0A182J4M1   A0A1L8DXU8   A0A0H4TY60   A0A2M4CMF8   Q16T45   B0X3W3   A0A1S4FQ35   W5JB46   T1HWZ8   A0A182LLJ7   Q7Q5T1   B0X3X6   A0A0A9YHM8   A0A146MB53   A0A1Y9J0F9   A0A146L5G6   Q16T47   A0A1U9X1S0   A0A182Q3A3   A0A182IIM6   A0A2M4B9W4   A0A182VPD9   A0A2M4BAH9   A0A182II50   A0A0N0PD45  

Pubmed

19121390    25803580    26778204    26354079    24817326    17904312    + More
22118469    21719571    18362917    19820115    20798317    23826341    25474469    28756777    20920257    23761445    24438588    17510324    20966253    12364791    14747013    17210077    25401762    26823975   

EMBL

BABH01001568    BABH01001569    BABH01001570    BABH01001571    BABH01001572    BABH01001573    + More
ODYU01004253    SOQ43930.1    LC017757    BAR64771.1    KP899546    AKQ06145.1    ODYU01001878    SOQ38698.1    KQ459606    KPI90950.1    NWSH01002143    PCG69059.1    LC017753    BAR64767.1    KF960795    AII21997.1    KF960794    AII21996.1    NWSH01000413    PCG76559.1    EU073424    ABW71272.1    RSAL01000229    RVE43893.1    ODYU01002537    SOQ40155.1    LC017752    BAR64766.1    AGBW02008082    OWR54176.1    KY595779    ARS46833.1    BABH01001657    BABH01001658    BABH01001659    BABH01001660    PCG76558.1    EU073423    ABW71271.1    PCG76561.1    KQ460556    KPJ13979.1    KY595778    ARS46832.1    KQ459193    KPJ03063.1    RSAL01000123    RVE46648.1    KQ982557    KYQ55014.1    KQ459674    KPJ20482.1    KQ979701    KYN19697.1    GL888413    EGI61333.1    KQ434912    KZC11368.1    KQ971466    EFA13012.2    KQ435826    KOX72014.1    KYN19698.1    KQ981281    KYN43332.1    KQ976546    KYM80948.1    KQ414670    KOC64413.1    KYQ55015.1    DS497731    EFA13013.1    KPI90999.1    NWSH01007172    PCG63055.1    ODYU01000376    SOQ35055.1    KZ288369    PBC26783.1    JR045677    AEY60027.1    NWSH01000648    PCG75033.1    GL441193    EFN65044.1    KQ977306    KYN03667.1    KY595781    ARS46835.1    GEDC01004862    JAS32436.1    KC952900    AGQ43599.1    KYN03668.1    LC017754    BAR64768.1    KQ769812    OAD52839.1    GBBI01004413    JAC14299.1    KQ461196    KPJ06614.1    KP859406    AKZ17716.1    AXCN02000553    PCG75032.1    KQ971307    EFA11446.2    NWSH01007964    PCG62737.1    KP859407    AKZ17717.1    PCG62736.1    DS232324    EDS40039.1    KZ150135    PZC72996.1    UFQS01000745    UFQT01000745    SSX06553.1    SSX26900.1    GFDL01004496    JAV30549.1    EDS40041.1    GFDL01008214    JAV26831.1    KF960796    AII21998.1    GFDL01008505    JAV26540.1    ADMH02001746    ETN61219.1    ATLV01024093    KE525349    KFB50588.1    KPI90997.1    GGFM01006571    MBW27322.1    GFDF01002797    JAV11287.1    KP899547    AKQ06146.1    GGFL01002295    MBW66473.1    CH477659    EAT37664.1    EDS40040.1    ETN61221.1    ACPB03000354    ACPB03000355    AAAB01008960    EAA11584.4    EDS40053.1    GBHO01014557    GBHO01014554    GBRD01002756    JAG29047.1    JAG29050.1    JAG63065.1    GDHC01013650    GDHC01001960    JAQ04979.1    JAQ16669.1    GDHC01015520    JAQ03109.1    EAT37662.1    KY643683    AQY62686.1    AXCN02000554    APCN01000032    GGFJ01000686    MBW49827.1    GGFJ01000687    MBW49828.1    APCN01000031    KQ460326    KPJ15694.1   

Proteomes

UP000005204    UP000053268    UP000218220    UP000283053    UP000007151    UP000053240    + More
UP000075809    UP000078492    UP000007755    UP000076502    UP000007266    UP000053105    UP000078541    UP000078540    UP000053825    UP000005203    UP000242457    UP000000311    UP000078542    UP000075886    UP000002320    UP000000673    UP000030765    UP000075903    UP000075880    UP000008820    UP000015103    UP000075882    UP000007062    UP000076407    UP000075840   

PRIDE

H9JFX4    A8TUC0    H9JFZ2    A8TUB4   

Pfam

PF01799   Fer2_2        + More
PF00941   FAD_binding_5
PF02738   Ald_Xan_dh_C2
PF01315   Ald_Xan_dh_C
PF03450   CO_deh_flav_C
PF00111   Fer2
PF01130   CD36
PF07651   ANTH

Interpro

IPR036683   CO_DH_flav_C_dom_sf        + More
IPR036856   Ald_Oxase/Xan_DH_a/b_sf       
IPR016166   FAD-bd_PCMH       
IPR002346   Mopterin_DH_FAD-bd       
IPR037165   AldOxase/xan_DH_Mopterin-bd_sf       
IPR000674   Ald_Oxase/Xan_DH_a/b       
IPR016208   Ald_Oxase/xanthine_DH       
IPR002888   2Fe-2S-bd       
IPR036884   2Fe-2S-bd_dom_sf       
IPR005107   CO_DH_flav_C       
IPR008274   AldOxase/xan_DH_Mopterin-bd       
IPR036318   FAD-bd_PCMH-like_sf       
IPR016169   FAD-bd_PCMH_sub2       
IPR006058   2Fe2S_fd_BS       
IPR036010   2Fe-2S_ferredoxin-like_sf       
IPR001041   2Fe-2S_ferredoxin-type       
IPR012675   Beta-grasp_dom_sf       
IPR002159   CD36_fam       
IPR013809   ENTH       
IPR008942   ENTH_VHS       
IPR011417   ANTH_dom       
IPR014712   Clathrin_AP_dom2       

SUPFAM

SSF47741   SSF47741        + More
SSF55447   SSF55447       
SSF56176   SSF56176       
SSF56003   SSF56003       
SSF54665   SSF54665       
SSF54292   SSF54292       
SSF48464   SSF48464       

Gene 3D

3.30.465.10     3.10.20.30     1.20.58.150     1.25.40.90    

CDD

cd00207  fer2

ProteinModelPortal

H9JFX4   A0A2H1VSX5   A0A0F7QEA3   A0A0H4TD12   A0A2H1VCW8   A0A194PIN2   + More
A0A2A4JB30   A0A0F7QJV6   A0A076FRA1   A0A076FX80   A0A2A4JXM9   A8TUC0   A0A3S2NMY0   A0A2H1VH28   A0A0F7QEA1   A0A212FKB8   A0A1X9ZM23   H9JFZ2   A0A2A4JY06   A8TUB4   A0A2A4JX39   A0A0N1I7K2   A0A1X9ZLZ6   A0A194QBY5   A0A3S2PBH0   A0A151X416   A0A0N0PF58   A0A195E465   F4WWU5   A0A154PJ92   D7EK61   A0A0N0BES0   A0A195E3I3   A0A195FSQ5   A0A151I2B1   A0A0L7R0P8   A0A151X3M2   D7EK62   A0A194PE80   A0A087ZYD0   A0A2A4ITG3   A0A2H1V2I4   A0A2A3E4V2   V9IH93   A0A2A4JU78   E2ANE4   A0A195CT20   A0A1X9ZM11   A0A1B6E3D0   S5FPI8   A0A195CSI2   A0A0F7QIE0   A0A310SF38   A0A023F0C3   A0A194QMP0   A0A0K1YW91   A0A182QVB6   A0A2A4JUF7   D6W6X3   A0A2A4IRV9   A0A0K1YWY0   A0A2A4ITB4   B0X3W2   A0A2W1BJJ3   A0A336MA50   A0A1Q3FSG4   B0X3W4   A0A1Q3FGZ2   A0A076FRM9   A0A1Q3FG61   W5JEG5   A0A084WK44   A0A194PCQ5   A0A2M3ZFL0   A0A182VKT2   A0A182J4M1   A0A1L8DXU8   A0A0H4TY60   A0A2M4CMF8   Q16T45   B0X3W3   A0A1S4FQ35   W5JB46   T1HWZ8   A0A182LLJ7   Q7Q5T1   B0X3X6   A0A0A9YHM8   A0A146MB53   A0A1Y9J0F9   A0A146L5G6   Q16T47   A0A1U9X1S0   A0A182Q3A3   A0A182IIM6   A0A2M4B9W4   A0A182VPD9   A0A2M4BAH9   A0A182II50   A0A0N0PD45  

PDB

4YTY     E-value=4.81148e-126,     Score=1160

KEGG

101739179    K00106 xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] | (RefSeq) indole-3-acetaldehyde oxidas

PATHWAY

00230    Purine metabolism - Bombyx mori (domestic silkworm)
00232    Caffeine metabolism - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0071949   GO:0051537   GO:0016491   GO:0005506   GO:0009055   GO:0046872   GO:0016021   GO:0050660   GO:0009115   GO:0004854   GO:0005829   GO:0030276   GO:0048268   GO:0030136   GO:0005545   GO:0102797   GO:0004031   GO:0102798   GO:0051536   GO:0003824   GO:0016614   GO:0055114  

Length:

1261

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.11721

Exp number, first 60 AAs:

0.00056

Total prob of N-in:

0.00286

outside

1  -  1261

 

 

Pi

224.107618

Theta

161.829112

Tajima's D

1.143938

CLR

0.559701

CSRT

0.697915104244788

Interpretation

Uncertain