Gene

KWMTBOMO10751

Pre Gene Modal

BGIBMGA008401

Annotation

PREDICTED:_alkaline_phosphatase-like_[Bombyx_mori]

Location

Bomo_Chr18(-):2397136-2410280      View in EpiBrowser

Full name

Alkaline phosphatase      

Location in the cell

Mitochondrial   Reliability : 1.976

CDS

ATGACATCGCGACATGCACACTCGACCCATGTTGCAACAGGACTGAGCAAAGTGCAAACTGAAGCAAAGCACCAACATGGGGACGGATCGCGAACGTTGATCCACACGTTGGGCGAGTGGCGTTGGTGCCTATGTTGGGGCCAACGTGTGGAGCCGGCGTTACGTATTGCACTAGTCCACGTGAATCTGACCGTGGCAGTGACTCATGCGTTCATTCACGAGTCAAATAAACGAAAGCGACGCGGTCTAGTCGTTGCCATGTTCCCGCGCATTTTACCTGTGTTCTTTGTTATTTACGCGGCAAAATGTACCTTACGAACAGACCAACAATTCTGGACGGAGCTGGCTGAGAACGAGCTAGCTGAGGCTTTGCAAGTCAAATGGAACCTTGGAGTCGCGAAGAACGTGATCCTCTTCGTCGGAGACGGCATGGGACCTAACACTGTGACGGCGACCAGGATATACAAAGGGGGAGAGAGTCACAGATTGGTTTACGAGAAGTTTCCACATGTTGGACTATTAAAGACATATTCAGCTAACAAAATGGTCCCAGACTCATCGTGTTCCGCCACGGCACTGTTCTGTGGGGTCAAAGCCAATCAAGAGACCATAGGAGTGGACGCTAGTGTGAAGCACAAGGATTGTTCTGCTTCGTTGAGGCCAGAAGCCAGGTTGAAGTCTTTAGCCTCGATAGCTCTGAAAGCTGGGAAGAGTGCTGGTTTTGTGACAACTATGCGAGTCACCCATGCGACCCCGGGTCCCATTTACGCCCACAGTGCTGATCGTAAATGGGAATGCGAAGACAAAATGCCTGCTAGCGCTGCTGCTTGCAAGGATATCGCGAGGCAACTTGTGGAAGACTGGCCCGGAAAAGACTTGCAGGTAATCCTAGGTGGAGGCAGACAGGTTCTTGTATCCAACAGCACAGGTACTAAAGAAGATCCATTAGATACGTGGTCTTGCATCAGAAAGGACGGTAAGGATCTCATAAAAGAATACCAGAAGGACAAACATGACCGCGGCTTGAGATATAGCTATGTATCAAATAACAAGCAGCTTAAAGGATTCGATGTTGACCAAACCGATTATCTTTTGGGAATCTTTGCAAACGGGCATCTAAAATATGAACACGAAAGAAACAAAGGTCCTGAAGGTATGCCTTCGATATCCGATATGGTCGAAGCCGCCATAAAAGTGTTACGGAAAAATAAAAACGGATACTTTCTTATGGTAGAAGGCGGCAATGTGGACATGGCCCACCACCGGGGCTGGGCCAAGCGCGCCATCGACGAGTCCGCGGCCCTCGAGGGCGCCGTGCGGCTCGCGGCTGCGCACACCGACCCCCGGGACACGCTGCTCGTCGTCACCAGCGACCACACGCACACGCTCTCCATCAACGGCTACCCCTACAGGGGCACTGATATATTTGACATAGCCCAAACTTCAAAATACGACAACGTGAACTACACGACGCTGTCATACGGCACCGGAGGCCCGGGCTCCATGAAGTACTCCGTGAAAACCGAACACAACAGGACCGTGGCCGCCAGAGAAGACCCCGGCGTCAACACCGACAGCTTCGACTACCAGCAGATAGCGGCCATCACTCTGGACGAGAACAGCCACGGGGGCGGAGACGTGGTGGTCTACGCGCGAGGTCCCCACGCTCATCTGTTCCACAACGTGCACGAGCAGCATTACGTGTACCACGCGATATCGTACGCCGCCAAAATGGGCGCCTACTCCGGAACCAGCGCCATCTATACCAACATTTCGTTGTTAGCAATCGCCGCCTGGGTTGCCATATGTATAATGAAATAA

Protein

MTSRHAHSTHVATGLSKVQTEAKHQHGDGSRTLIHTLGEWRWCLCWGQRVEPALRIALVHVNLTVAVTHAFIHESNKRKRRGLVVAMFPRILPVFFVIYAAKCTLRTDQQFWTELAENELAEALQVKWNLGVAKNVILFVGDGMGPNTVTATRIYKGGESHRLVYEKFPHVGLLKTYSANKMVPDSSCSATALFCGVKANQETIGVDASVKHKDCSASLRPEARLKSLASIALKAGKSAGFVTTMRVTHATPGPIYAHSADRKWECEDKMPASAAACKDIARQLVEDWPGKDLQVILGGGRQVLVSNSTGTKEDPLDTWSCIRKDGKDLIKEYQKDKHDRGLRYSYVSNNKQLKGFDVDQTDYLLGIFANGHLKYEHERNKGPEGMPSISDMVEAAIKVLRKNKNGYFLMVEGGNVDMAHHRGWAKRAIDESAALEGAVRLAAAHTDPRDTLLVVTSDHTHTLSINGYPYRGTDIFDIAQTSKYDNVNYTTLSYGTGGPGSMKYSVKTEHNRTVAAREDPGVNTDSFDYQQIAAITLDENSHGGGDVVVYARGPHAHLFHNVHEQHYVYHAISYAAKMGAYSGTSAIYTNISLLAIAAWVAICIMK

Catalytic Activity

a phosphate monoester + H2O = an alcohol + phosphate

Similarity

Belongs to the alkaline phosphatase family.

Feature

chain  Alkaline phosphatase

Uniprot

H9JFV4   A0A2A4K1R0   A0A0F6PQM1   A0A194PCE0   A0A0L7L7G6   A0A3S2LY03   + More
I6PFJ3   M4M5S9   A0A2H1WHP5   A0A0C9S0U6   A0A3L8DSF8   A0A088AME9   A0A195EYH1   A0A1B6IP91   A0A158NST0   A0A1B6GLC5   A0A1B6ECT8   A0A1B6DR19   E2A827   A0A224XEP7   E2C0T1   T1I0Y8   A0A151X5Q1   A0A1S3CWV3   F4WSI0   A0A151IF46   E0VGW0   A0A310SDV0   A0A2A3EHG5   A0A151I269   A0A232ET19   K7ING2   A0A023F5X3   A0A1L8DK51   N6UBH1   A0A139WDX0   A0A026WZL9   A0A151J5W5   A0A0M9A8U3   A0A0L7RCL8   A0A1B0DA98   A0A2K8JUQ2   A0A1B6DWL1   A0A2R7WWP8   G9FJB7   A0A034VJQ3   A0A0K8U2I9   A0A0A1WTC6   W8BLC1   A0A146KZL8   B4MAX3   A0A0A9X175   A0A3Q0IMU6   B4JKH0   B4L5F8   A0A2L1IQA3   A0A1I8NM94   A0A1S6J0W4   J9K4Y9   A0A0P4VQ65   A0A0M4FAL4   T1PDQ4   B4NCA1   A0A154P1P3   A0A1B0ETD4   B4I5U7   A0A1B0G202   B4Q9X6   Q9VIW9   A8E6R0   B3NM60   B4PAY1   B3MNL4   A0A1W4VF53   A0A0L0BPJ3   A0A0P4W4R7   A0A1W7RB25   A0A2R7VSC7   A0A3R7Q821   A0A2P2I2V2   E9G5V0   A0A087T3L1   A0A0N7ZVC0   K1PG91   A0A164UQ76   A0A0P6DU62   A0A0P5N5D5   A0A0P6GHS2   A0A0N8DZ40   A0A0P5PD28   A0A0P6DU59   A0A0P5S4X1   A0A0N8CA82   A0A0N8EFT7   A0A0P5PQ56   A0A0N8AQD9   A0A0P5NQF6   A0A0N8C2B6  

EC Number

3.1.3.1

Pubmed

19121390    25662100    26354079    26227816    30249741    21347285    + More
20798317    21719571    20566863    28648823    20075255    25474469    23537049    18362917    19820115    24508170    22984624    25348373    25830018    24495485    26823975    17994087    18057021    25401762    29415259    27414796    27129103    25315136    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    26108605    21292972    22992520   

EMBL

BABH01001554    NWSH01000253    PCG77999.1    KM244031    AKC42324.1    KQ459606    + More
KPI90956.1    JTDY01002499    KOB71284.1    RSAL01000124    RVE46598.1    JF979063    AFI81419.1    JQ747497    AGG36454.1    ODYU01008734    SOQ52588.1    GBYB01014231    JAG83998.1    QOIP01000004    RLU23344.1    KQ981923    KYN32957.1    GECU01018965    JAS88741.1    ADTU01025137    GECZ01006515    JAS63254.1    GEDC01001540    JAS35758.1    GEDC01009183    JAS28115.1    GL437468    EFN70422.1    GFTR01006952    JAW09474.1    GL451846    EFN78475.1    ACPB03021812    ACPB03025252    KQ982494    KYQ55733.1    GL888322    EGI62845.1    KQ977808    KYM99548.1    DS235152    EEB12616.1    KQ762882    OAD55347.1    KZ288248    PBC31160.1    KQ976549    KYM80894.1    NNAY01002345    OXU21501.1    GBBI01002119    JAC16593.1    GFDF01007235    JAV06849.1    APGK01041602    APGK01041603    KB740994    KB632255    ENN75992.1    ERL90648.1    KQ971357    KYB26031.1    KK107054    EZA61510.1    KQ979928    KYN18595.1    KQ435711    KOX79580.1    KQ414615    KOC68544.1    AJVK01013241    AJVK01013242    KY031024    ATU82775.1    GEDC01007224    JAS30074.1    KK855543    PTY23055.1    JN135240    AEV66507.1    GAKP01016907    JAC42045.1    GDHF01031340    GDHF01028429    GDHF01028065    GDHF01023895    GDHF01009316    JAI20974.1    JAI23885.1    JAI24249.1    JAI28419.1    JAI42998.1    GBXI01012604    JAD01688.1    GAMC01008737    GAMC01008736    GAMC01008735    JAB97818.1    GDHC01016838    JAQ01791.1    CH940655    EDW66382.1    KRF82644.1    KRF82645.1    GBHO01029882    GBHO01029870    JAG13722.1    JAG13734.1    CH916370    EDW00073.1    CH933811    EDW06417.1    MF741668    AVD96951.1    KU764424    AQS60671.1    ABLF02010432    GDKW01003278    JAI53317.1    CP012528    ALC49837.1    KA646048    AFP60677.1    CH964239    EDW82460.1    KRF99618.1    KQ434796    KZC05781.1    CCAG010014407    CCAG010014408    CH480822    EDW55753.1    CM000361    CM002910    EDX05506.1    KMY91003.1    AE014134    AAF53795.1    ADV37097.1    ADV37098.1    AGB93110.1    AGB93111.1    BT030852    ABV82234.1    CH954179    EDV54660.1    CM000158    EDW90410.1    KRJ99163.1    KRJ99164.1    CH902620    EDV31101.1    JRES01001651    KNC21149.1    GDRN01072395    JAI63554.1    GFAH01000056    JAV48333.1    KK854047    PTY10249.1    QCYY01002370    ROT70910.1    IACF01002718    LAB68362.1    GL732533    EFX85107.1    KK113248    KFM59700.1    GDIP01208977    JAJ14425.1    JH816532    EKC20593.1    LRGB01001579    KZS11573.1    GDIQ01072354    JAN22383.1    GDIQ01146885    GDIQ01146884    GDIQ01145531    JAL04842.1    GDIQ01033013    GDIQ01032023    JAN61724.1    GDIQ01222108    GDIQ01153371    GDIQ01077748    GDIQ01046619    GDIQ01003628    JAN16989.1    GDIQ01130379    GDIQ01130378    GDIQ01061357    JAL21348.1    GDIQ01245354    GDIQ01157767    GDIQ01155573    GDIQ01081759    GDIQ01081758    GDIQ01072353    GDIQ01064619    JAN22384.1    GDIQ01182324    GDIQ01096697    GDIQ01096696    GDIQ01065961    GDIQ01065960    JAL55029.1    GDIQ01099604    GDIQ01099603    GDIQ01063119    JAL52123.1    GDIQ01190561    GDIQ01182323    GDIQ01134377    GDIQ01030972    JAN63765.1    GDIQ01232140    GDIQ01184715    GDIQ01163875    GDIQ01125937    JAL25789.1    GDIQ01253147    GDIQ01245353    GDIQ01169214    JAJ98577.1    GDIQ01144132    GDIQ01141711    JAL10015.1    GDIQ01184717    GDIQ01184716    GDIQ01163874    GDIQ01127531    GDIQ01121731    JAL29995.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000037510    UP000283053    UP000279307    + More
UP000005203    UP000078541    UP000005205    UP000000311    UP000008237    UP000015103    UP000075809    UP000079169    UP000007755    UP000078542    UP000009046    UP000242457    UP000078540    UP000215335    UP000002358    UP000019118    UP000030742    UP000007266    UP000053097    UP000078492    UP000053105    UP000053825    UP000092462    UP000008792    UP000001070    UP000009192    UP000095300    UP000007819    UP000092553    UP000095301    UP000007798    UP000076502    UP000092444    UP000001292    UP000000304    UP000000803    UP000008711    UP000002282    UP000007801    UP000192221    UP000037069    UP000283509    UP000000305    UP000054359    UP000005408    UP000076858   

PRIDE

H9JFV4    Q9VIW9    A8E6R0   

Pfam

PF00245   Alk_phosphatase        + More
PF00001   7tm_1
PF00579   tRNA-synt_1b

Interpro

IPR017850   Alkaline_phosphatase_core_sf        + More
IPR001952   Alkaline_phosphatase       
IPR018299   Alkaline_phosphatase_AS       
IPR017452   GPCR_Rhodpsn_7TM       
IPR024088   Tyr-tRNA-ligase_bac-type       
IPR000276   GPCR_Rhodpsn       
IPR002305   aa-tRNA-synth_Ic       
IPR002307   Tyr-tRNA-ligase       
IPR036986   S4_RNA-bd_sf       
IPR014729   Rossmann-like_a/b/a_fold       
IPR001412   aa-tRNA-synth_I_CS       

SUPFAM

SSF53649   SSF53649       

Gene 3D

3.40.720.10     3.10.290.10     3.40.50.620    

CDD

cd16012  ALP
cd00805  TyrRS_core

ProteinModelPortal

H9JFV4   A0A2A4K1R0   A0A0F6PQM1   A0A194PCE0   A0A0L7L7G6   A0A3S2LY03   + More
I6PFJ3   M4M5S9   A0A2H1WHP5   A0A0C9S0U6   A0A3L8DSF8   A0A088AME9   A0A195EYH1   A0A1B6IP91   A0A158NST0   A0A1B6GLC5   A0A1B6ECT8   A0A1B6DR19   E2A827   A0A224XEP7   E2C0T1   T1I0Y8   A0A151X5Q1   A0A1S3CWV3   F4WSI0   A0A151IF46   E0VGW0   A0A310SDV0   A0A2A3EHG5   A0A151I269   A0A232ET19   K7ING2   A0A023F5X3   A0A1L8DK51   N6UBH1   A0A139WDX0   A0A026WZL9   A0A151J5W5   A0A0M9A8U3   A0A0L7RCL8   A0A1B0DA98   A0A2K8JUQ2   A0A1B6DWL1   A0A2R7WWP8   G9FJB7   A0A034VJQ3   A0A0K8U2I9   A0A0A1WTC6   W8BLC1   A0A146KZL8   B4MAX3   A0A0A9X175   A0A3Q0IMU6   B4JKH0   B4L5F8   A0A2L1IQA3   A0A1I8NM94   A0A1S6J0W4   J9K4Y9   A0A0P4VQ65   A0A0M4FAL4   T1PDQ4   B4NCA1   A0A154P1P3   A0A1B0ETD4   B4I5U7   A0A1B0G202   B4Q9X6   Q9VIW9   A8E6R0   B3NM60   B4PAY1   B3MNL4   A0A1W4VF53   A0A0L0BPJ3   A0A0P4W4R7   A0A1W7RB25   A0A2R7VSC7   A0A3R7Q821   A0A2P2I2V2   E9G5V0   A0A087T3L1   A0A0N7ZVC0   K1PG91   A0A164UQ76   A0A0P6DU62   A0A0P5N5D5   A0A0P6GHS2   A0A0N8DZ40   A0A0P5PD28   A0A0P6DU59   A0A0P5S4X1   A0A0N8CA82   A0A0N8EFT7   A0A0P5PQ56   A0A0N8AQD9   A0A0P5NQF6   A0A0N8C2B6  

PDB

1K7H     E-value=1.10732e-86,     Score=817

KEGG

101743834    K01077 alkaline phosphatase [EC:3.1.3.1] | (RefSeq) alkaline phosphatase-like

PATHWAY

00730    Thiamine metabolism - Bombyx mori (domestic silkworm)
00790    Folate biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0004035   GO:0016791   GO:0004930   GO:0043039   GO:0003723   GO:0004831   GO:0005524   GO:0006437   GO:0005829   GO:0005739   GO:0009986   GO:0016311   GO:0008152   GO:0003824   GO:0016020   GO:0005515   GO:0016491   GO:0046872   GO:0051537  

PANTHER

PTHR11596   PTHR11766  

Length:

606

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

40.87954

Exp number, first 60 AAs:

0.53691

Total prob of N-in:

0.87571

inside

1  -  81

TMhelix

82  -  101

outside

102  -  579

TMhelix

580  -  602

inside

603  -  606

 

 

Pi

212.452048

Theta

158.953738

Tajima's D

1.064755

CLR

0.125705

CSRT

0.67821608919554

Interpretation

Uncertain