Gene

KWMTBOMO10692  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008268

Annotation

PREDICTED:_xanthine_dehydrogenase_2-like_[Bombyx_mori]

Location

Bomo_Chr18(+):626820-631484      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.001 Extracellular   Reliability : 1.199 Nuclear   Reliability : 1.553

CDS

ATGTGTCGTCAGGCCGGTTGCGGTGCTTGCATAGTGGCAGCTAAACGTCCGGACCGTCGTACGAATGAAGCTGTCAATTCGTGCATGGTCCCGATAACATCCTGTCAAAATTGGGAAATAACAACCATAGAAGGAGTGGGAAATAGGAATAAAGGATACCACCCTTTACAAAAAAGTCTAGCAGCTAACAACGGTAGCCAGTGTGGTTACTGTTCGCCGGGATGGGTTATGTCTATGTACAGCCTTTTGCAGCAATACAAAGCCCCAAGAATGATAGAAATCGAAAAACTACTAGGGTCTAACGTCTGCAGATGTACTGGGTACAGACCAATTTTAGATGCCTTCAAATCTTTCGCTAAAGATGCTCCGAAAAATCTAATTTCTGATATTGAAGACTTAGTCATTTGTAAGAAGACCGGACAGCCTTGCGATAATCCATGCGATGAAGAAGATTGGTGCTTGGTGAATAAAGAGGACGCTGATGAGCCGAACACGATTAGGATAGAATTGTGTGACGGAAGACTTTTTTTTAAGGTTTTTAAAATAAGTGAAATTCTGCGACTATTGGTAACGGAGAATTATGATTCTTACCAACTTGTTTGGGGAAATACGGCTAGAGGTGCATATCCAACAGATGTGCGCGCCCAGCTATTAATAGATATAACGGGGGTAAATGAATTAAAGGGATATTACTTGGATCAGAATCTGGTCATCAATGCTGGAACAACCTTGACTGAATTGATGAATATCTATAAAAAACTGTCAGAAAAAGAAGAGGACTTTCAATATTTAGACCGGTTTTATGAGCATTTGGAAATGGTAGCTCATGTTGCTGTCAGAAATTATTAG

Protein

MCRQAGCGACIVAAKRPDRRTNEAVNSCMVPITSCQNWEITTIEGVGNRNKGYHPLQKSLAANNGSQCGYCSPGWVMSMYSLLQQYKAPRMIEIEKLLGSNVCRCTGYRPILDAFKSFAKDAPKNLISDIEDLVICKKTGQPCDNPCDEEDWCLVNKEDADEPNTIRIELCDGRLFFKVFKISEILRLLVTENYDSYQLVWGNTARGAYPTDVRAQLLIDITGVNELKGYYLDQNLVINAGTTLTELMNIYKKLSEKEEDFQYLDRFYEHLEMVAHVAVRNY

Cofactor

FAD
Mo-molybdopterin
[2Fe-2S] cluster

Uniprot

H9JFH1   A0A2W1BGZ9   A0A3S2M0B9   A0A2H1VZA4   A0A2H1V6B6   A0A0N0PDI7   + More
A0A3S2PBH0   A0A2A4ISI6   A0A2W1BJJ3   A0A2A4IRV9   A0A2A4ITB4   H9JFE7   A0A0N0PD45   A0A2A4JUF7   A0A194PDB3   A0A0F7QIE4   A0A194PCQ5   A0A0N1IAK3   A0A2W1BHI1   A0A2H1V2I4   A0A2H1VA65   A0A2A4ITG3   A0A2W1BIK1   A0A194PE80   A0A194QBY5   A0A2A4JU78   A0A0N0PF58   A0A212FI14   A0A2W1BIE3   A0A2H1VDX2   A0A1X9ZM11   A0A194QUG5   A0A194PIT3   A0A1X9ZM28   A0A0L7L4A2   A0A0L7L438   A0A212EVU1   A0A2A4IZZ7   A0A0L7L4E9   A0A3S2NDD1   A0A212EZ25   A0A0F7QEA3   A0A2H1VA49   A0A0F7QEA1   A0A0H4TD12   A0A3S2P6B3   A0A2A4JXM9   A0A194PIN2   A0A2A4JYR8   A0A2H1VSX5   A0A2H1VH28   A0A1L8D6Q4   A8TUB4   H9JFZ2   A0A0F7QJV6   A0A194PDZ5   Q4VGM3   A0A212FKB8   A0A212F791   A0A0F7QIE0   A0A2H1V7P8   A0A1L8D6P5   A0A1X9ZM23   A0A194QM53   A0A194PCA1   A0A2A4JX39   A0A0H4TY60   H9JFZ3   A0A1X9ZLZ6   A0A3S2NMY0   A0A194QMP0   U5EY22   A0A076FX80   A0A336MA50   A0A2H1VCW8   A8TUC0   A0A2H1WKN9   A0A1B6E3D0   J9HG89   A0A0A9YA60   A0A0N1I7K2   A0A2H1WDE7   A0A0L7R0P8   A0A1J1J883   A0A0A9YHM8   A0A146MB53   A0A146L5G6   S5FPI8   A0A023F0C3   A0A084WK44   A0A0L7L3S0   H9JFZ8   A0A1Q3FGZ2   A0A182GP55   A0A182QKS2   A0A1U9X1S0   A0A2R7WMZ6   B0X3W4   A0A1L8DXU3   A0A182GGE2  

Pubmed

19121390    28756777    26354079    25803580    22118469    26227816    + More
26778204    17904312    15896291    24817326    17510324    25401762    26823975    23826341    25474469    24438588    26483478   

EMBL

BABH01034958    BABH01034959    BABH01034960    BABH01034961    BABH01034962    BABH01034963    + More
BABH01034964    BABH01034965    KZ150135    PZC72995.1    RSAL01000088    RVE48203.1    ODYU01005369    SOQ46133.1    ODYU01000882    SOQ36316.1    KQ460326    KPJ15692.1    RSAL01000123    RVE46648.1    NWSH01007964    PCG62735.1    PZC72996.1    PCG62737.1    PCG62736.1    BABH01034979    BABH01034980    BABH01034981    KPJ15694.1    NWSH01000648    PCG75032.1    KQ459606    KPI90998.1    LC017759    BAR64773.1    KPI90997.1    KPJ15693.1    KZ150165    PZC72657.1    ODYU01000376    SOQ35055.1    ODYU01001481    SOQ37735.1    NWSH01007172    PCG63055.1    PZC72656.1    KPI90999.1    KQ459193    KPJ03063.1    PCG75033.1    KQ459674    KPJ20482.1    AGBW02008446    OWR53382.1    PZC72997.1    ODYU01002030    SOQ39029.1    KY595781    ARS46835.1    KQ461154    KPJ08620.1    KPI91000.1    KY595780    ARS46834.1    JTDY01003017    KOB70302.1    JTDY01003130    KOB70096.1    AGBW02012116    OWR45615.1    NWSH01004179    PCG65395.1    JTDY01003022    KOB70290.1    RVE48202.1    AGBW02011403    OWR46707.1    LC017757    BAR64771.1    ODYU01001472    SOQ37709.1    LC017752    BAR64766.1    KP899546    AKQ06145.1    RSAL01000295    RVE42846.1    NWSH01000413    PCG76559.1    KPI90950.1    PCG76560.1    ODYU01004253    SOQ43930.1    ODYU01002537    SOQ40155.1    GEYN01000001    JAV02128.1    EU073423    ABW71271.1    BABH01001657    BABH01001658    BABH01001659    BABH01001660    LC017753    BAR64767.1    KPI90909.1    AY947538    AAY22446.1    AGBW02008082    OWR54176.1    AGBW02009901    OWR49607.1    LC017754    BAR64768.1    ODYU01001109    SOQ36868.1    GEYN01000003    JAV02126.1    KY595779    ARS46833.1    KQ461196    KPJ06623.1    KPI90901.1    PCG76561.1    KP899547    AKQ06146.1    BABH01001661    KY595778    ARS46832.1    RSAL01000229    RVE43893.1    KPJ06614.1    GANO01002236    JAB57635.1    KF960794    AII21996.1    UFQS01000745    UFQT01000745    SSX06553.1    SSX26900.1    ODYU01001878    SOQ38698.1    EU073424    ABW71272.1    ODYU01009314    SOQ53643.1    GEDC01004862    JAS32436.1    CH477659    EJY57867.1    GBHO01014555    GBHO01014552    JAG29049.1    JAG29052.1    KQ460556    KPJ13979.1    ODYU01007852    SOQ50986.1    KQ414670    KOC64413.1    CVRI01000075    CRL08599.1    GBHO01014557    GBHO01014554    GBRD01002756    JAG29047.1    JAG29050.1    JAG63065.1    GDHC01013650    GDHC01001960    JAQ04979.1    JAQ16669.1    GDHC01015520    JAQ03109.1    KC952900    AGQ43599.1    GBBI01004413    JAC14299.1    ATLV01024093    KE525349    KFB50588.1    JTDY01003126    KOB70107.1    BABH01001678    BABH01001679    GFDL01008214    JAV26831.1    JXUM01002771    KQ560144    KXJ84188.1    AXCN02000553    KY643683    AQY62686.1    KK855082    PTY20711.1    DS232324    EDS40041.1    GFDF01002872    JAV11212.1    JXUM01061540    KQ562154    KXJ76553.1   

Proteomes

UP000005204    UP000283053    UP000053240    UP000218220    UP000053268    UP000007151    + More
UP000037510    UP000008820    UP000053825    UP000183832    UP000030765    UP000069940    UP000249989    UP000075886    UP000002320   

PRIDE

H9JFH1    H9JFE7    A8TUB4    H9JFZ2    H9JFZ3    A8TUC0    + More
H9JFZ8   

Pfam

PF02738   Ald_Xan_dh_C2        + More
PF01315   Ald_Xan_dh_C
PF03450   CO_deh_flav_C
PF00111   Fer2
PF00941   FAD_binding_5
PF01799   Fer2_2
PF00271   Helicase_C
PF01130   CD36

Interpro

IPR000674   Ald_Oxase/Xan_DH_a/b        + More
IPR002888   2Fe-2S-bd       
IPR036884   2Fe-2S-bd_dom_sf       
IPR005107   CO_DH_flav_C       
IPR008274   AldOxase/xan_DH_Mopterin-bd       
IPR036318   FAD-bd_PCMH-like_sf       
IPR001041   2Fe-2S_ferredoxin-type       
IPR036010   2Fe-2S_ferredoxin-like_sf       
IPR036683   CO_DH_flav_C_dom_sf       
IPR036856   Ald_Oxase/Xan_DH_a/b_sf       
IPR006058   2Fe2S_fd_BS       
IPR016166   FAD-bd_PCMH       
IPR002346   Mopterin_DH_FAD-bd       
IPR037165   AldOxase/xan_DH_Mopterin-bd_sf       
IPR016208   Ald_Oxase/xanthine_DH       
IPR012675   Beta-grasp_dom_sf       
IPR016169   FAD-bd_PCMH_sub2       
IPR027417   P-loop_NTPase       
IPR002464   DNA/RNA_helicase_DEAH_CS       
IPR014001   Helicase_ATP-bd       
IPR001650   Helicase_C       
IPR002159   CD36_fam       

SUPFAM

SSF54665   SSF54665        + More
SSF54292   SSF54292       
SSF55447   SSF55447       
SSF56176   SSF56176       
SSF56003   SSF56003       
SSF47741   SSF47741       
SSF52540   SSF52540       

Gene 3D

3.10.20.30     3.30.465.10    

CDD

cd00207  fer2
cd00079  HELICc

ProteinModelPortal

H9JFH1   A0A2W1BGZ9   A0A3S2M0B9   A0A2H1VZA4   A0A2H1V6B6   A0A0N0PDI7   + More
A0A3S2PBH0   A0A2A4ISI6   A0A2W1BJJ3   A0A2A4IRV9   A0A2A4ITB4   H9JFE7   A0A0N0PD45   A0A2A4JUF7   A0A194PDB3   A0A0F7QIE4   A0A194PCQ5   A0A0N1IAK3   A0A2W1BHI1   A0A2H1V2I4   A0A2H1VA65   A0A2A4ITG3   A0A2W1BIK1   A0A194PE80   A0A194QBY5   A0A2A4JU78   A0A0N0PF58   A0A212FI14   A0A2W1BIE3   A0A2H1VDX2   A0A1X9ZM11   A0A194QUG5   A0A194PIT3   A0A1X9ZM28   A0A0L7L4A2   A0A0L7L438   A0A212EVU1   A0A2A4IZZ7   A0A0L7L4E9   A0A3S2NDD1   A0A212EZ25   A0A0F7QEA3   A0A2H1VA49   A0A0F7QEA1   A0A0H4TD12   A0A3S2P6B3   A0A2A4JXM9   A0A194PIN2   A0A2A4JYR8   A0A2H1VSX5   A0A2H1VH28   A0A1L8D6Q4   A8TUB4   H9JFZ2   A0A0F7QJV6   A0A194PDZ5   Q4VGM3   A0A212FKB8   A0A212F791   A0A0F7QIE0   A0A2H1V7P8   A0A1L8D6P5   A0A1X9ZM23   A0A194QM53   A0A194PCA1   A0A2A4JX39   A0A0H4TY60   H9JFZ3   A0A1X9ZLZ6   A0A3S2NMY0   A0A194QMP0   U5EY22   A0A076FX80   A0A336MA50   A0A2H1VCW8   A8TUC0   A0A2H1WKN9   A0A1B6E3D0   J9HG89   A0A0A9YA60   A0A0N1I7K2   A0A2H1WDE7   A0A0L7R0P8   A0A1J1J883   A0A0A9YHM8   A0A146MB53   A0A146L5G6   S5FPI8   A0A023F0C3   A0A084WK44   A0A0L7L3S0   H9JFZ8   A0A1Q3FGZ2   A0A182GP55   A0A182QKS2   A0A1U9X1S0   A0A2R7WMZ6   B0X3W4   A0A1L8DXU3   A0A182GGE2  

PDB

4YTZ     E-value=2.68355e-28,     Score=310

KEGG

101736569    K00106 xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] | (RefSeq) xanthine dehydrogenase 2

PATHWAY

00230    Purine metabolism - Bombyx mori (domestic silkworm)
00232    Caffeine metabolism - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0071949   GO:0009055   GO:0046872   GO:0051537   GO:0005506   GO:0016491   GO:0050660   GO:0016021   GO:0102797   GO:0004031   GO:0102798   GO:0003824   GO:0016614   GO:0051536   GO:0055114  

Length:

282

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0492000000000001

Exp number, first 60 AAs:

0.00469

Total prob of N-in:

0.10668

outside

1  -  282

 

 

Pi

230.179802

Theta

145.569451

Tajima's D

2.26049

CLR

0.000645

CSRT

0.91960401979901

Interpretation

Uncertain