Gene

KWMTBOMO10649  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA014431

Annotation

serine_protease_precursor_[Bombyx_mori]

Location

Bomo_Chr18(+):63266-67252      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 2.407

CDS

ATGAAGGTCTTCGCAGCAGTACTGATGGCGTTGGCGGCCGTGGTCGTGGCAGAAGAGGCTATCGAACTTGACTACCACACCAAGATCGGTATCCCCCGGGCCGAGAGTCTTAAGCGCGCCGAGGAAGCCGCTGACTTCGACGGTACCAGGATTGTGGGTGGTTCTGCCGCCAACGCTGGTGCTCACCCCCATCTTGCTGGACTTGTGATCGCACTCACGAATGGCAGAACTTCAATCTGCGGAGCTTCCTTACTGACCAACACCCGCTCTGTGACCGCTGCTCACTGCTGGAGGTCCAGGGATGCCCAGGCTCGTCAGTTCACCCTCGCTTTTGGCACAGCTAACATCTTCTCCGGAGGCACCAGGGTCACCACCTCCAGTGTCCATATGCACGGCAGCTACAACATGAACAACCTCCACAATGACGTCGCCGTCATCAACCACAACCATGTTGGCTTCAACAACAACATTCAGCGCATCAACCTAGCCAGTGGAAGCAACAACTTTGCTGGTACTTGGGCCTGGGCTGCCGGCTTCGGCAGAACTTCCGATGCTGCTTCGGGAGCCAACAACCAACAAAAACGCCAAGTCAGCCTTCAGGTCATTACTAACGCCGTCTGCGCCCGGACTTTTGGAAACACTCTGATCATTGGCTCCACCCTCTGTGTTGACGGCTCTAACGGTCGCAGCACCTGCAGGGGAGACTCCGGCGGCCCTCTCACCATCGGCAGCGGCGGAGGCCGTCAGCTGATCGGTATCACATCGTTCGGATCAGCCCAAGGCTGCCAGAGAGGCTTCCCCGCCGCCTTCGCCAGAGTCACATCTTTTAACTCCTGGATCCGGGCTAGAATTTAA

Protein

MKVFAAVLMALAAVVVAEEAIELDYHTKIGIPRAESLKRAEEAADFDGTRIVGGSAANAGAHPHLAGLVIALTNGRTSICGASLLTNTRSVTAAHCWRSRDAQARQFTLAFGTANIFSGGTRVTTSSVHMHGSYNMNNLHNDVAVINHNHVGFNNNIQRINLASGSNNFAGTWAWAAGFGRTSDAASGANNQQKRQVSLQVITNAVCARTFGNTLIIGSTLCVDGSNGRSTCRGDSGGPLTIGSGGGRQLIGITSFGSAQGCQRGFPAAFARVTSFNSWIRARI

Similarity

Belongs to the peptidase S1 family.
Belongs to the ETS family.

Uniprot

Q762I9   Q58I79   H9JY13   Q58I80   H9JY11   O01953   + More
H9JY10   H9JY12   A0A194Q3W8   A0A194Q399   H9JY09   T1WJA5   A0A3S2LL18   A0A0N0PAA7   A0A194Q0R8   A0A2W1BAG4   A0A194R2V7   A0A0N0PCX7   A0A0N0PAA9   A0A0N0PA14   A0A2H1WCW9   A0A0N1PGY7   A0A0N1IFV7   A0A0N1IAY5   Q56IC0   C9W8H4   A0A2A4JJ77   A0A089QFN1   A0A0N1PIX2   I6TRU6   A0A0M4LSN9   A0A212EYA6   A0A0M3T9F4   A0A0N1I5V5   H9JCY0   I6SW50   B2ZJV9   Q9NH07   A0A0N0PEU9   A0A0N1PHR5   A0A1B0RHP3   A0A0N1ICZ9   J7FDV3   O18450   A0A2A4JSJ6   O18445   A0A194QCZ1   A0A2A4K228   O18444   A0A2A4K0D3   A0A2A4K1C2   Q9N6C6   A0A2A4K1Q8   B4X987   B4X988   A0A1E1WV21   H9JJ25   E7D003   A0PGD7   A0A142I706   C9W8F9   C9W8G8   D7RZZ8   D7RZZ6   D2Y4U4   B6CMF0   D7RZZ7   D7RZZ9   B4X990   A0PGE0   C7FF06   B6D1R1   B4X989   A0A0L7L962   A0A2A4J6X3   A0A2A4J8H7   C9W8H8   O18443   E7D008   A9P3S5   Q86M89   A0A2H1V6V4   I6TEX2   A0A194PUF7   A0PGD6   A0A194QK37   Q9NH10   E7D013   J7FCZ4   A0A089RSZ3   A0A2A4JFK9   C9W8G7   A0A194QF72   A0PGD5   A0A2H1V6R8   E2D741   O18438   E7D007   A0A0L7KVY7   S5QJ14  

Pubmed

15033574    19121390    10380113    26354079    28756777    16469064    + More
20824821    22118469    11267902    22228503    9404008    18760362    20696895    20149796    21322004    19133073    26227816    19146482    19194984    23606528   

EMBL

AB117641    BAD13342.1    AY945211    DQ310733    AAX39409.1    ABC26003.1    + More
BABH01041861    AY945210    EU338400    AAX39408.1    ABY58153.1    BABH01041853    BABH01042790    AB003670    BAA20136.1    BABH01041852    BABH01041859    BABH01041860    KQ459472    KPJ00237.1    KQ459586    KPI97880.1    BABH01041868    KF039687    AGU27161.1    RSAL01000073    RVE48982.1    KQ458725    KPJ05397.1    KQ459581    KPI99177.1    KZ150191    PZC72392.1    KQ460845    KPJ12032.1    KQ460401    KPJ14971.1    KPJ05400.1    KQ458978    KPJ04519.1    ODYU01007826    SOQ50918.1    KQ461033    KPJ09997.1    KQ460140    KPJ17495.1    KPJ05401.1    AY953056    AY953057    AAX62029.1    AAX62030.1    FJ205420    ACR15987.3    NWSH01001385    PCG71452.1    KM083780    AIR09761.1    KPJ17496.1    JQ904141    AFM77771.1    KR024679    ALE15221.1    AGBW02011570    OWR46476.1    KR024680    ALE15222.1    KPJ05396.1    BABH01027594    JQ904140    AFM77770.1    EU672968    ACD44927.1    AF233732    AAF71519.1    KQ459620    KPJ20544.1    KPJ17494.1    KM360186    AKH49602.1    KQ459388    KPJ01122.1    JN252035    AFM28248.1    Y12287    CAA72966.1    NWSH01000651    PCG75015.1    Y12281    CAA72960.1    KQ459185    KPJ03332.1    NWSH01000291    PCG77692.1    Y12280    CAA72959.1    PCG77697.1    PCG77694.1    AF233731    AF233734    AAF71518.1    AAF71716.1    PCG77693.1    EF531623    ABR88234.1    PCG77696.1    EF531624    ABR88235.1    GDQN01000181    JAT90873.1    BABH01023267    HM990173    ADT80821.1    AY618892    AAV33655.1    KT907053    AMR44225.1    FJ205404    ACR15972.2    FJ205413    ACR15981.1    HM209421    ADI32882.1    HM209419    ADI32880.1    GU323796    ADA83701.1    EU325550    ACB54940.1    HM209420    ADI32881.1    HM209422    ADI32883.1    EF531626    ABR88237.1    AY618895    AAV33658.1    GQ354838    ACU00133.1    EU673454    ACI45417.1    EF531625    ABR88236.1    JTDY01002254    KOB71786.1    NWSH01002619    PCG67835.1    PCG67834.1    FJ205424    ACR15991.1    Y12279    CAA72958.1    HM990178    ADT80826.1    EF104914    ABP96916.1    AY251276    AAO75039.1    ODYU01000971    SOQ36529.1    JQ904139    AFM77769.1    KQ459591    KPI97041.1    AY618891    AAV33654.1    KQ461198    KPJ05938.1    AF233728    AAF71515.1    HM990183    ADT80831.1    JN252036    AFM28249.1    KM083791    AIR09772.1    SOQ36530.1    NWSH01001552    PCG70875.1    FJ205412    ACR15980.1    KQ459252    KPJ02116.1    AY618890    AAV33653.1    SOQ36528.1    GQ891130    ADK27715.1    Y12273    CAA72952.1    HM990177    ADT80825.1    JTDY01005262    KOB67184.1    KC175563    AGR92346.1   

Proteomes

UP000005204    UP000053268    UP000283053    UP000053240    UP000218220    UP000007151    + More
UP000037510   

PRIDE

Q762I9    Q58I79    H9JY13    H9JY11    O01953    H9JY10    + More
H9JY12    H9JY09    H9JCY0    H9JJ25   

Pfam

PF00089   Trypsin        + More
PF00178   Ets

Interpro

IPR009003   Peptidase_S1_PA        + More
IPR001314   Peptidase_S1A       
IPR018114   TRYPSIN_HIS       
IPR001254   Trypsin_dom       
IPR033116   TRYPSIN_SER       
IPR036388   WH-like_DNA-bd_sf       
IPR036390   WH_DNA-bd_sf       
IPR000418   Ets_dom       

SUPFAM

SSF50494   SSF50494        + More
SSF46785   SSF46785       

Gene 3D

1.10.10.10    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

Q762I9   Q58I79   H9JY13   Q58I80   H9JY11   O01953   + More
H9JY10   H9JY12   A0A194Q3W8   A0A194Q399   H9JY09   T1WJA5   A0A3S2LL18   A0A0N0PAA7   A0A194Q0R8   A0A2W1BAG4   A0A194R2V7   A0A0N0PCX7   A0A0N0PAA9   A0A0N0PA14   A0A2H1WCW9   A0A0N1PGY7   A0A0N1IFV7   A0A0N1IAY5   Q56IC0   C9W8H4   A0A2A4JJ77   A0A089QFN1   A0A0N1PIX2   I6TRU6   A0A0M4LSN9   A0A212EYA6   A0A0M3T9F4   A0A0N1I5V5   H9JCY0   I6SW50   B2ZJV9   Q9NH07   A0A0N0PEU9   A0A0N1PHR5   A0A1B0RHP3   A0A0N1ICZ9   J7FDV3   O18450   A0A2A4JSJ6   O18445   A0A194QCZ1   A0A2A4K228   O18444   A0A2A4K0D3   A0A2A4K1C2   Q9N6C6   A0A2A4K1Q8   B4X987   B4X988   A0A1E1WV21   H9JJ25   E7D003   A0PGD7   A0A142I706   C9W8F9   C9W8G8   D7RZZ8   D7RZZ6   D2Y4U4   B6CMF0   D7RZZ7   D7RZZ9   B4X990   A0PGE0   C7FF06   B6D1R1   B4X989   A0A0L7L962   A0A2A4J6X3   A0A2A4J8H7   C9W8H8   O18443   E7D008   A9P3S5   Q86M89   A0A2H1V6V4   I6TEX2   A0A194PUF7   A0PGD6   A0A194QK37   Q9NH10   E7D013   J7FCZ4   A0A089RSZ3   A0A2A4JFK9   C9W8G7   A0A194QF72   A0PGD5   A0A2H1V6R8   E2D741   O18438   E7D007   A0A0L7KVY7   S5QJ14  

PDB

2HLC     E-value=5.56906e-24,     Score=273

KEGG

692447    no KO assigned | (RefSeq) Sp; serine protease

GO

GO:0004252   GO:0003700   GO:0043565   GO:0005634   GO:0006508   GO:0003676   GO:0020037   GO:0006457   GO:0003906   GO:0006285   GO:0019104   GO:0003824  

Subcellular location

Nucleus  

SignalP

Position:   1 - 17,         Likelihood:  0.994043

 

 

Length:

284

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.45156

Exp number, first 60 AAs:

0.25631

Total prob of N-in:

0.03887

outside

1  -  284

 

 

Pi

184.144471

Theta

141.671693

Tajima's D

1.51963

CLR

0

CSRT

0.782310884455777

Interpretation

Uncertain