Gene

KWMTBOMO10625

Pre Gene Modal

BGIBMGA003956

Annotation

PREDICTED:_15-hydroxyprostaglandin_dehydrogenase_[NAD(+)]-like_[Papilio_machaon]

Location

Bomo_Chr17(+):16081447-16082369      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.958

CDS

ATGGAACGCGAATTGAAAAATAAAATTGTTGCCATAACGGGAGGAGCTGAAGGCATAGGCCTCAGTATCGCCGATCAATTCCTCAGCGAAGGCGCAGTCGTCGTGATACTCGATATAAACTTGGAGAAAGGACAAAATGCAGCCAAAGAATTGCAAAGCAAGCACGGCGCTACGAAGGTCAGTTTCTTAAGATGCGATGTTACGACCGATCTGGAATCGGTATTCAATCAGCTCATAGATGCTCACAAACGTGTTGACGTCTTGGTGAACAACGCCGGGATCATATGCGAGAGTTCATTGAGGAAGACTCTTGAAATAAACACTGTGGCTCCCATCGAGTGGACGGTGAAGTTTAGAGAGTACATGAGGACAGATAAGGGTGGGAGTGGTGGCACAATTTGCAATGTATCATCGATATACGGCTATTGCCTAGACCCGTATTTGCCGTATTACAAAGCTTCGAAGTTTGCTCTATTCGGCTTCAGCACTACGTTAGGACATAAGCAGAATTACGACAGAACTGGGGTAAGAATCGTGACTGTGTGCCCCGGGTTTACAAGCTCAGCCATGACAGCACAACTGACGGTGTGGGATGAGCACGTTGAAGAGTTTGCGGCTCAGAGGAGCCAGCTGAAGTGGCAAACTCCTGCGCAGGTCGGTACCGGTGTCGCTGAGCTGTTCAGGGTCGCCGATAGTGGGACAGCCTGGGCTATCATAGGGGGAGAACCAATTAAGCAAGTAGAGCAAAGATGTCTCAAATAA

Protein

MERELKNKIVAITGGAEGIGLSIADQFLSEGAVVVILDINLEKGQNAAKELQSKHGATKVSFLRCDVTTDLESVFNQLIDAHKRVDVLVNNAGIICESSLRKTLEINTVAPIEWTVKFREYMRTDKGGSGGTICNVSSIYGYCLDPYLPYYKASKFALFGFSTTLGHKQNYDRTGVRIVTVCPGFTSSAMTAQLTVWDEHVEEFAAQRSQLKWQTPAQVGTGVAELFRVADSGTAWAIIGGEPIKQVEQRCLK

Similarity

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Uniprot

H9J369   A0A194R4F0   A0A194QJQ6   S4PIB4   A0A1L8D6N5   A0A194R584   + More
A0A194R949   A0A0H4TDA9   A0A0L7KQW0   A0A0L7LJP6   U5KC20   A0A212F911   A0A2H1VSR5   A0A2W1BSK9   A0A0F6Q0X5   I4DKW3   A0A2A4JIR0   A0A0H4TD16   A0A194R3L5   D2SNK3   A0A2H1VNC8   A0A2W1BR60   A0A212F936   A0A0F6Q0W0   H9JWW1   A0A0F6Q2J9   A0A2W1BL60   H9JYK0   H9J8I5   H9J8I4   A0A2H1VR53   H9JWW7   A0A0H4TH26   H9JWW0   A0A0F6Q4H7   Q1HPX6   H9J8J0   H9J8I9   H9JWW6   H9J354   A0A0L7K2F9   H9J8I6   A0A076FT29   H9J353   H9J355   A0A2A4JJW8   A0A194QRC6   A0A194QE27   A0A212F0G1   H9J0A6   A0A2P8Z2R9   A0A069DY58   A0A023F7A3   A0A224XI56   A0A212F0F9   A0A224XI78   A0A023FB52   A0A195CN33   G8JKE8   A0A151WLU8   Q6RUR3   A0A3G1T1B2   A0A0H4TG49   G8JKD9   A0A0J7NFD4   A0A158NDP0   A0A3S2NMK6   E9IVH7   A0A158NZK6   A0A194QQX1   R4FLI9   J3JY31   A0A151XEI7   A0A3S2PLF3   A0A1S3IM65   A0A1Y1MAW1   A0A195B6A6   U4U4R0   A0A194QA14   A0A293LHH0   A0A0L7QT43   A0A1Z5L6W3   N6UBZ4   U4TZN1   A0A1S3KGT2   A0A0J7L0X1   A0A0N1IPP9   A0A1S3IUI5   A0A0P4WG45   A0A212F0I1   F4W474   B3V0K9   A0A212F0G8   A0A194QA61   A0A151XEL1   A0A195DA18   A0A154PCJ3  

Pubmed

19121390    26354079    23622113    26227816    24053512    22118469    + More
28756777    22651552    20074338    24817326    29403074    26334808    25474469    22679863    21347285    21282665    22516182    28004739    23537049    28528879    21719571    18622569   

EMBL

BABH01036649    KQ460779    KPJ12399.1    KQ459144    KPJ03686.1    GAIX01005455    + More
JAA87105.1    GEYN01000013    JAV02116.1    KPJ12400.1    KPJ12396.1    KP899549    AKQ06148.1    JTDY01007189    KOB65394.1    JTDY01000876    KOB75589.1    KC007343    AGQ45608.1    AGBW02009651    OWR50236.1    ODYU01003911    SOQ43254.1    KZ149989    PZC75626.1    KP237899    AKD01752.1    AK401931    BAM18553.1    KPJ03685.1    NWSH01001322    PCG71699.1    KP899551    AKQ06150.1    KPJ12398.1    EZ407131    ACX53694.1    ODYU01003471    SOQ42306.1    PZC75627.1    OWR50237.1    KP237884    AKD01737.1    BABH01043464    KP237873    AKD01726.1    PZC75628.1    BABH01044234    BABH01027529    BABH01027530    BABH01027525    SOQ43256.1    BABH01040078    KP899550    AKQ06149.1    BABH01043465    KP237875    AKD01728.1    DQ443276    ABF51365.1    BABH01027538    BABH01036642    JTDY01017041    KOB51868.1    BABH01027533    KF960802    AII22004.1    BABH01036648    PCG71700.1    KQ461175    KPJ07894.1    KQ459302    KPJ01716.1    AGBW02011082    OWR47236.1    BABH01019209    PYGN01000223    PSN50783.1    GBGD01002580    JAC86309.1    GBBI01001633    JAC17079.1    GFTR01004259    JAW12167.1    OWR47238.1    GFTR01004241    JAW12185.1    GBBI01000005    JAC18707.1    KQ977600    KYN01499.1    JP593077    AER92462.1    KQ982944    KYQ48859.1    AY491503    AAR84629.1    MG846919    AXY94771.1    KP899548    AKQ06147.1    JP593068    AER92453.1    LBMM01005734    KMQ91250.1    ADTU01012731    RSAL01000003    RVE54803.1    GL766234    EFZ15444.1    ADTU01004714    KPJ07892.1    ACPB03004191    GAHY01001368    JAA76142.1    BT128155    AEE63116.1    KQ982254    KYQ58773.1    RVE54802.1    GEZM01036109    GEZM01036108    JAV82969.1    KQ976587    KYM79714.1    KB631724    ERL85591.1    KQ459249    KPJ02363.1    GFWV01001510    MAA26240.1    KQ414755    KOC61724.1    GFJQ02004022    JAW02948.1    APGK01029527    APGK01029528    APGK01029529    KB740735    ENN79175.1    KB631805    ERL86287.1    LBMM01001364    KMQ96442.1    KQ460366    KPJ15603.1    GDRN01065431    JAI64685.1    OWR47240.1    GL887491    EGI71070.1    EU622636    ACF19426.1    OWR47239.1    KPJ02362.1    KYQ58797.1    KQ981082    KYN09728.1    KQ434870    KZC09507.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000037510    UP000007151    UP000218220    + More
UP000245037    UP000078542    UP000075809    UP000036403    UP000005205    UP000283053    UP000015103    UP000085678    UP000078540    UP000030742    UP000053825    UP000019118    UP000007755    UP000078492    UP000076502   

PRIDE

H9J369    H9JWW1    H9JYK0    H9J8I5    H9J8I4    H9JWW7    + More
H9JWW0    Q1HPX6    H9J8J0    H9J8I9    H9JWW6    H9J354    H9J8I6    H9J353    H9J355    H9J0A6   

Pfam

PF00106   adh_short

Interpro

IPR002347   SDR_fam        + More
IPR036291   NAD(P)-bd_dom_sf       
IPR020904   Sc_DH/Rdtase_CS       

SUPFAM

SSF51735   SSF51735       

ProteinModelPortal

H9J369   A0A194R4F0   A0A194QJQ6   S4PIB4   A0A1L8D6N5   A0A194R584   + More
A0A194R949   A0A0H4TDA9   A0A0L7KQW0   A0A0L7LJP6   U5KC20   A0A212F911   A0A2H1VSR5   A0A2W1BSK9   A0A0F6Q0X5   I4DKW3   A0A2A4JIR0   A0A0H4TD16   A0A194R3L5   D2SNK3   A0A2H1VNC8   A0A2W1BR60   A0A212F936   A0A0F6Q0W0   H9JWW1   A0A0F6Q2J9   A0A2W1BL60   H9JYK0   H9J8I5   H9J8I4   A0A2H1VR53   H9JWW7   A0A0H4TH26   H9JWW0   A0A0F6Q4H7   Q1HPX6   H9J8J0   H9J8I9   H9JWW6   H9J354   A0A0L7K2F9   H9J8I6   A0A076FT29   H9J353   H9J355   A0A2A4JJW8   A0A194QRC6   A0A194QE27   A0A212F0G1   H9J0A6   A0A2P8Z2R9   A0A069DY58   A0A023F7A3   A0A224XI56   A0A212F0F9   A0A224XI78   A0A023FB52   A0A195CN33   G8JKE8   A0A151WLU8   Q6RUR3   A0A3G1T1B2   A0A0H4TG49   G8JKD9   A0A0J7NFD4   A0A158NDP0   A0A3S2NMK6   E9IVH7   A0A158NZK6   A0A194QQX1   R4FLI9   J3JY31   A0A151XEI7   A0A3S2PLF3   A0A1S3IM65   A0A1Y1MAW1   A0A195B6A6   U4U4R0   A0A194QA14   A0A293LHH0   A0A0L7QT43   A0A1Z5L6W3   N6UBZ4   U4TZN1   A0A1S3KGT2   A0A0J7L0X1   A0A0N1IPP9   A0A1S3IUI5   A0A0P4WG45   A0A212F0I1   F4W474   B3V0K9   A0A212F0G8   A0A194QA61   A0A151XEL1   A0A195DA18   A0A154PCJ3  

PDB

2GDZ     E-value=6.0215e-30,     Score=324

KEGG

101745613    K00069 15-hydroxyprostaglandin dehydrogenase (NAD) [EC:1.1.1.141] | (RefSeq) 15-hydroxyprostaglandin

GO

GO:0004022   GO:0016491   GO:0016021  

Length:

253

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.09207

Exp number, first 60 AAs:

0.10744

Total prob of N-in:

0.16781

outside

1  -  253

 

 

Pi

119.661326

Theta

120.537943

Tajima's D

0.018352

CLR

0.37139

CSRT

0.377481125943703

Interpretation

Uncertain