Gene

KWMTBOMO10549  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006973

Annotation

PREDICTED:_cytosolic_Fe-S_cluster_assembly_factor_NUBP2_homolog_[Papilio_polytes]

Location

Bomo_Chr17(-):13762526-13767671      View in EpiBrowser

Full name

Cytosolic Fe-S cluster assembly factor NUBP2 homolog       + More
Cytosolic Fe-S cluster assembly factor NUBP2 homolog 1      
Cytosolic Fe-S cluster assembly factor NUBP2 homolog 2      

Location in the cell

Cytoplasmic   Reliability : 1.385

CDS

ATGAAATATTGTACAAAAATGTCAAATGGTGATGAGGGCGCTAGGTTCGCGCTCGCAACATTGTCGGATTCGTTGGTTGTATACCCAACTTCAATGTTGTTGATCGAAGATACCAAAGATCAAGTAAAACGCGTGTTATTAGTGCTTTCCGGCAAAGGTGGCGTCGGTAAATCAACAGTGAGCACACAGTTGGCACTAACTCTAAAAGAAAGAGGTTACAAGGTTGGTTTATTAGACATAGATTTATGTGGCCCAAGCGTACCTTACATTTTGAATCTCGAAGGCCATGATGTCCACCAGAGCGCTGAAGGTTGGGTACCAGTTTACATGGACAGCGAACAGAGGCTCGGTGTCCTGTCGATTGGATTCCTACTAACATCTCGTAATGATTCTGTTGTATTAAGGGGACCAAAAAAGACTTCCATAATCAAACAGTTCCTAGAAGATGTTTATTGGCAAGAGCTAGACTTTTTGGTTATAGATACACCTCCAGGAACATCTGATGAACACATAACTGTTATGGAGAATCTTCGTCAAGTACCACAATGTTCTGCCATACTAGTGACCACACCACAAGAAGTGGCAATAGAAGACGTACGCAAAGAAATTACATTCTGTAGAAAAACTGGCATTCCTATAATGGGTCTTATAGAAAATATGAGTGGATATGAATGTCCAAACTGCAGTGAATGCACTAATATATTCTCTACTGGAGGAGGCCAATCTTTGGCAGAATATGCAAAAATTCCATTCCTGGGCAGCGTACCCATTGATCCTAGAGTTGGTAGATTAGCTGGTCAAGGTCTCTGCGCTGTTAAAGAACTTCCAGACTCGAAAACCAGCAAAGTATTTGGGGAATTAGTAACTCTATTGGGGGAGAATTCAAATGGCGTAAACTGA

Protein

MKYCTKMSNGDEGARFALATLSDSLVVYPTSMLLIEDTKDQVKRVLLVLSGKGGVGKSTVSTQLALTLKERGYKVGLLDIDLCGPSVPYILNLEGHDVHQSAEGWVPVYMDSEQRLGVLSIGFLLTSRNDSVVLRGPKKTSIIKQFLEDVYWQELDFLVIDTPPGTSDEHITVMENLRQVPQCSAILVTTPQEVAIEDVRKEITFCRKTGIPIMGLIENMSGYECPNCSECTNIFSTGGGQSLAEYAKIPFLGSVPIDPRVGRLAGQGLCAVKELPDSKTSKVFGELVTLLGENSNGVN

Description

Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.

Cofactor

[4Fe-4S] cluster

Subunit

Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

Similarity

Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.

Keywords

4Fe-4S   ATP-binding   Complete proteome   Cytoplasm   Iron   Iron-sulfur   Metal-binding   Nucleotide-binding   Reference proteome  

Feature

chain  Cytosolic Fe-S cluster assembly factor NUBP2 homolog

Uniprot

H9JBS8   A0A2H1VSY8   A0A2A4JEG3   A0A194RJC6   A0A194PIA5   A0A212EI29   + More
A0A1L8DWU6   A0A1L8DWR7   A0A1B0DE57   A0A336MTB7   A0A182KVL4   Q7QGS3   A0A182U3E2   A0A182VA06   A0A182I5I5   A0A182X416   A0A1J1IJX9   Q16H50   A0A182YMG4   A0A151K055   A0A084WUR9   U5ETQ3   A0A2M4AR95   A0A232FCK0   A0A2M3ZBA6   A0A2M4BXC8   A0A1Q3FI23   A0A151I2M5   A0A158P1B9   F4WA15   A0A026X156   A0A182PAX7   A0A182FVR3   A0A2M4AR47   A0A1W4WRN2   A0A2M4ASA4   A0A1B0CKB1   A0A1Q3FLF7   A0A0J7KUR0   A0A1Q3FKW6   A0A151XH88   W5JTC8   A0A182J594   A0A1B6MP14   A0A151IPY7   A0A067QLJ1   B0XDJ0   A0A182K6V4   A0A182GTM5   E9IQ45   A0A2J7QEB3   A0A1B6FFG3   A0A182Q367   A0A195DL38   A0A1B6IWL9   A0A088AR65   A0A154PQW4   A0A182MFM6   E2ATX4   A0A1Y1L4F4   A0A2A3EAY1   A0A0L7REW2   D6WVY6   E2BQK7   A0A1B6DI30   A0A0N1ITC2   J3JVV5   A0A182W2C5   B4IUH5   B4IAD1   B3NIP2   B3M9R3   A0A182N369   A0A0J9RYT9   B4QJ46   A0A182GYE9   B4PES4   Q9VPD2   B4IYG8   A0A0K8TTN4   A0A3B0JMX3   A0A0M4EMW7   B4N4D9   B4LGB4   B4KY56   A0A0L0C3L0   A0A0R3P7C1   Q29DB7   A0A1W4W6N8   A0A182R572   A0A1L8ED24   A0A1I8MFB7   A0A0A9Y463   A0A1I8PP77   A0A2S2R2V3  

Pubmed

19121390    26354079    22118469    20966253    12364791    17510324    + More
25244985    24438588    28648823    21347285    21719571    24508170    30249741    20920257    23761445    24845553    26483478    21282665    20798317    28004739    18362917    19820115    22516182    23537049    17994087    22936249    10731132    12537572    26369729    26108605    15632085    25315136    25401762    26823975   

EMBL

BABH01015108    ODYU01004269    SOQ43961.1    NWSH01001875    PCG69830.1    KQ460124    + More
KPJ17657.1    KQ459603    KPI93141.1    AGBW02014713    OWR41135.1    GFDF01003147    JAV10937.1    GFDF01003193    JAV10891.1    AJVK01032571    UFQS01001853    UFQT01001853    SSX12570.1    SSX32013.1    AAAB01008823    APCN01003445    CVRI01000054    CRL00539.1    CH478204    CH477488    KQ981301    KYN43037.1    ATLV01027105    KE525423    KFB53963.1    GANO01001799    JAB58072.1    GGFK01009994    MBW43315.1    NNAY01000465    OXU28179.1    GGFM01005086    MBW25837.1    GGFJ01008521    MBW57662.1    GFDL01007847    JAV27198.1    KQ976535    KYM81456.1    ADTU01006215    GL888037    EGI68945.1    KK107046    QOIP01000004    EZA61736.1    RLU24203.1    GGFK01009928    MBW43249.1    GGFK01010328    MBW43649.1    AJWK01015958    AJWK01015959    GFDL01006606    JAV28439.1    LBMM01003073    KMQ93999.1    GFDL01006901    JAV28144.1    KQ982138    KYQ59671.1    ADMH02000429    ETN66538.1    GEBQ01002287    JAT37690.1    KQ976836    KYN07966.1    KK853286    KDR08947.1    DS232762    JXUM01087473    JXUM01087474    JXUM01087475    KQ563635    KXJ73575.1    GL764659    EFZ17356.1    NEVH01015316    PNF26939.1    GECZ01021076    JAS48693.1    AXCN02001123    KQ980762    KYN13588.1    GECU01016362    JAS91344.1    KQ435010    KZC13744.1    AXCM01002708    GL442747    EFN63105.1    GEZM01065085    JAV68562.1    KZ288313    PBC28346.1    KQ414608    KOC69354.1    KQ971359    EFA08218.1    GL449769    EFN82065.1    GEDC01012013    JAS25285.1    KQ435837    KOX71474.1    APGK01035650    BT127373    KB740928    KB632064    AEE62335.1    ENN77901.1    ERL88454.1    CH891909    CH480826    CH954178    CH902618    CM002912    KMZ00832.1    CM000363    JXUM01021127    KQ560592    KXJ81745.1    CM000159    AE014296    BT012307    CH916366    GDAI01000298    JAI17305.1    OUUW01000002    SPP76830.1    CP012525    ALC45122.1    CH964095    CH940647    CH933809    JRES01000945    KNC26928.1    CH379070    KRT09009.1    GFDG01002171    JAV16628.1    GBHO01045500    GBHO01045499    GBHO01040199    GBHO01040195    GBHO01040194    GBHO01040193    GBHO01016647    GBHO01016646    GBHO01016645    GBHO01016644    GBHO01016643    GBHO01016642    GBHO01016641    GBHO01016639    GBRD01013480    GBRD01013479    GDHC01014233    GDHC01013523    GDHC01012541    GDHC01007553    JAF98103.1    JAF98104.1    JAG03405.1    JAG03409.1    JAG03410.1    JAG03411.1    JAG26957.1    JAG26958.1    JAG26959.1    JAG26960.1    JAG26961.1    JAG26962.1    JAG26963.1    JAG26965.1    JAG52346.1    JAQ04396.1    JAQ05106.1    JAQ06088.1    JAQ11076.1    GGMS01015123    MBY84326.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000092462    + More
UP000075882    UP000007062    UP000075902    UP000075903    UP000075840    UP000076407    UP000183832    UP000008820    UP000076408    UP000078541    UP000030765    UP000215335    UP000078540    UP000005205    UP000007755    UP000053097    UP000279307    UP000075885    UP000069272    UP000192223    UP000092461    UP000036403    UP000075809    UP000000673    UP000075880    UP000078542    UP000027135    UP000002320    UP000075881    UP000069940    UP000249989    UP000235965    UP000075886    UP000078492    UP000005203    UP000076502    UP000075883    UP000000311    UP000242457    UP000053825    UP000007266    UP000008237    UP000053105    UP000019118    UP000030742    UP000075920    UP000002282    UP000001292    UP000008711    UP000007801    UP000075884    UP000000304    UP000000803    UP000001070    UP000268350    UP000092553    UP000007798    UP000008792    UP000009192    UP000037069    UP000001819    UP000192221    UP000075900    UP000095301    UP000095300   

PRIDE

H9JBS8    Q16H50    B4IUH5    B4IAD1    B3NIP2    B3M9R3    + More
B4QJ46    B4PES4    Q9VPD2    B4IYG8    B4LGB4    Q29DB7   

Pfam

PF10609   ParA        + More
PF02535   Zip

Interpro

IPR033756   YlxH/NBP35        + More
IPR000808   Mrp_CS       
IPR028600   NUBP2/Cfd1_eukaryotes       
IPR019591   Mrp/NBP35_ATP-bd       
IPR027417   P-loop_NTPase       
IPR003689   ZIP       

SUPFAM

SSF52540   SSF52540       

CDD

cd02037  MRP-like

ProteinModelPortal

H9JBS8   A0A2H1VSY8   A0A2A4JEG3   A0A194RJC6   A0A194PIA5   A0A212EI29   + More
A0A1L8DWU6   A0A1L8DWR7   A0A1B0DE57   A0A336MTB7   A0A182KVL4   Q7QGS3   A0A182U3E2   A0A182VA06   A0A182I5I5   A0A182X416   A0A1J1IJX9   Q16H50   A0A182YMG4   A0A151K055   A0A084WUR9   U5ETQ3   A0A2M4AR95   A0A232FCK0   A0A2M3ZBA6   A0A2M4BXC8   A0A1Q3FI23   A0A151I2M5   A0A158P1B9   F4WA15   A0A026X156   A0A182PAX7   A0A182FVR3   A0A2M4AR47   A0A1W4WRN2   A0A2M4ASA4   A0A1B0CKB1   A0A1Q3FLF7   A0A0J7KUR0   A0A1Q3FKW6   A0A151XH88   W5JTC8   A0A182J594   A0A1B6MP14   A0A151IPY7   A0A067QLJ1   B0XDJ0   A0A182K6V4   A0A182GTM5   E9IQ45   A0A2J7QEB3   A0A1B6FFG3   A0A182Q367   A0A195DL38   A0A1B6IWL9   A0A088AR65   A0A154PQW4   A0A182MFM6   E2ATX4   A0A1Y1L4F4   A0A2A3EAY1   A0A0L7REW2   D6WVY6   E2BQK7   A0A1B6DI30   A0A0N1ITC2   J3JVV5   A0A182W2C5   B4IUH5   B4IAD1   B3NIP2   B3M9R3   A0A182N369   A0A0J9RYT9   B4QJ46   A0A182GYE9   B4PES4   Q9VPD2   B4IYG8   A0A0K8TTN4   A0A3B0JMX3   A0A0M4EMW7   B4N4D9   B4LGB4   B4KY56   A0A0L0C3L0   A0A0R3P7C1   Q29DB7   A0A1W4W6N8   A0A182R572   A0A1L8ED24   A0A1I8MFB7   A0A0A9Y463   A0A1I8PP77   A0A2S2R2V3  

PDB

6G2G     E-value=1.85022e-63,     Score=614

KEGG

101740890    no KO assigned | (RefSeq) cytosolic Fe-S cluster assembly factor NUBP2 homolog

GO

GO:0005524   GO:0016226   GO:0051539   GO:0046872   GO:0005737   GO:0051536   GO:0005829   GO:0046873   GO:0016021   GO:0005840   GO:0006284   GO:0003906   GO:0005634   GO:0006285   GO:0019104   GO:0003824  

PANTHER

PTHR23264  

Subcellular location

Cytoplasm  

Length:

299

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.61174

Exp number, first 60 AAs:

2.56188

Total prob of N-in:

0.21865

outside

1  -  299

 

 

Pi

15.679647

Theta

15.460605

Tajima's D

-0.827287

CLR

0.448649

CSRT

0.168741562921854

Interpretation

Uncertain