Gene

KWMTBOMO10540  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007136

Annotation

PREDICTED:_uncharacterized_protein_LOC106120989_[Papilio_xuthus]

Location

Bomo_Chr17(+):13585802-13596359      View in EpiBrowser

Full name

Sulfide:quinone oxidoreductase, mitochondrial      

Alternative Name

Sulfide quinone oxidoreductase
Sulfide dehydrogenase-like

Location in the cell

Mitochondrial   Reliability : 2.111

CDS

ATGAATACAGCACGATTGTTGAGTTTTGTATCATCGTCCAACGTATGTAGAAACTTCTCAAGTTCTTCAATATGTAATGCAAATTATTCATGTAAGCTGCTAGTTGTTGGTGGAGGATCGGGTGGTTGCACAGTTGCTGCTAAATTCGCCCGTAGACTGAATAAAGACTCTGTCATTATTTTGGAACCTAGTAATGATCATTACTATCAGCCCCTTTTCACTCTGGTAGGAGCCGGAGTGAAACGTGTGAGCGACACTAGGAGATCCGCACAGAGCGTGTTACCTAAAGCAGCGAAATGGCTGAGAGATTCCGCCGAAACGATTAACGCCAAAGCGAATGTTGTGACGACGAAAGATGGACACGTCATCAATTACGAGTACATCGTTATCGCTGTTGGACTGAAGAGCGATTATAATAAAATTCCAGGCTTGACTGAGGCGCTAAACGACACTAGCAGCGGCGTGTCTACGATATATGCGCCGGAGTACTGCGAGAAGACCTGGTCTGACCTGCAGATGTTCAAGGGCGGCGAGGCCATCTTCACTTACCCGGAGACGCTGATCAAGTGTCCAGGAGCGCCGCAGAAAATTGCCTATTTAGCTGAGTCTTATTTTACCAAGACGAATGTTCGTTCGAAATCGAACATAACGTACAACACGTGCCTGCCCGTTATCTTCGGAGTGAAGAAGTACGCCGACGCGCTCCTGAAGGTGGTGGAACGGAAGAAGATCAACGTCAATTACAAGACGGTGCTCAAAGAAGTCAAACCAGACAGGAGAGAAGCGGTTTTCTACAACACTGACGACAAGACTAAGGAAACAACAATGCAATACAACATGCTCCACGTGACTCCGCCGATGAAGACCCCGGATTTCCTGCAGCGGAGTAGCGACATTGTGGACCCTAATGGCTACCTGACCGTCAACAAATATACACTGCAGCACGACAAATATCCCAACGTTTACGGCATCGGAGACTGTACCAACACTCCGAACAGCAAGACCGCCGCTGCCATTGCCAAACAATGCTACGTGCTCGAACACAATTTACTTGGTACGATGCAAAAAGATGAGCCGAAGTTAAAATACGACGGGTACGGAGCGTGCCCCCTCCTCACAGCGTACGGGAAGTGTATACTGGCCGAGTTCATTTACGACGGAATACCGCATGAAACCTTGCCCTTCGATCAGGCCCGAGAGAGCGCGTTAGCGTATTACATGAAGAAGGATCTATTCCCCTTCCTATACTGGAACTTGATGCTCAAAGGTCGTTATCACGGACCGGAATTTGTGAGAAAAATTATAAACCCATTGGCTAAGTAA

Protein

MNTARLLSFVSSSNVCRNFSSSSICNANYSCKLLVVGGGSGGCTVAAKFARRLNKDSVIILEPSNDHYYQPLFTLVGAGVKRVSDTRRSAQSVLPKAAKWLRDSAETINAKANVVTTKDGHVINYEYIVIAVGLKSDYNKIPGLTEALNDTSSGVSTIYAPEYCEKTWSDLQMFKGGEAIFTYPETLIKCPGAPQKIAYLAESYFTKTNVRSKSNITYNTCLPVIFGVKKYADALLKVVERKKINVNYKTVLKEVKPDRREAVFYNTDDKTKETTMQYNMLHVTPPMKTPDFLQRSSDIVDPNGYLTVNKYTLQHDKYPNVYGIGDCTNTPNSKTAAAIAKQCYVLEHNLLGTMQKDEPKLKYDGYGACPLLTAYGKCILAEFIYDGIPHETLPFDQARESALAYYMKKDLFPFLYWNLMLKGRYHGPEFVRKIINPLAK

Description

Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro).

Catalytic Activity

2 H(+) + hydrogen sulfide + sulfite + ubiquinone-10 = thiosulfate + ubiquinol-10

Cofactor

FAD

Similarity

Belongs to the SQRD family.

Keywords

Acetylation   Complete proteome   FAD   Flavoprotein   Mitochondrion   Oxidoreductase   Phosphoprotein   Quinone   Reference proteome   Transit peptide   3D-structure   Polymorphism  

Feature

chain  Sulfide:quinone oxidoreductase, mitochondrial
sequence variant  In dbSNP:rs1044032.

Uniprot

H9JC91   A0A2A4JSL8   A0A212EI09   A0A0N1PIL3   A0A1Y1MLF7   A0A2H1VBR8   + More
D6WBW8   A0A182MF88   A0A2S2NC75   K7ITL0   J9K3J1   A0A1B6EDK7   A0A2Y9HII5   A0A182Q5Z9   A0A2U3X809   E9GXZ9   A0A2P2HYF4   A0A2H8TZS5   A0A182RYB8   A0A2M4AN29   C1BVL2   A0A2M4ANA4   A0A3Q2CNB5   B0WB42   A0A1Q3FHA1   A0A026W0M0   G3T2B9   B0BMT9   U5ER07   A0A1I8Q6U3   A0A182J8G8   A0A182K873   A0A3Q7WMN3   A0A3L8DN89   A0A3B3XGH5   A0A3B3U2B8   M3YIB5   A0A0K8U3B6   A0A0K8U8S2   G9KR37   A0A2U3ZP87   A0A084VZY0   A0A3Q4GBD8   A0A1L8E0E0   A0A3Q7S5U2   H2TPY3   G1M1P3   A0A182PTM6   A0A2Y9L9M2   A0A3P9PNL2   E2QTQ8   I3JNW4   A0A3Q7RHH5   A0A182HJ34   Q7QBJ7   A0A1Y9IRX1   U6CRH4   A0A286ZL94   F6Y205   A0A3Q3CHS0   A0A384BI12   B2R7T6   A0A3B4GZ10   A0A3P8NXK9   A0A3P9B7C1   A0A087XD32   A0A182XVJ5   A0A2M4D198   G1P4X2   A0A3B3C5G1   A0A3Q1JZ42   A0A1S3EP62   A0A3P9H957   H2LK25   A0A1L8E0V8   G3HMD2   A0A2K6EYL3   H2TPY4   W5JBD9   Q9R112   A0A3P9KR36   M3ZZ68   A0A1S4F0P9   A0A2M4CQ95   K7AI60   G1T782   A0A3S2MB41   G3NSH9   A0A0A1WIQ4   G3NSH3   A0A146P8J3   A0A3Q1IMN3   A0A3P8W6E5   H2Q9D6   A0A2R9CMM4   M3W7Y3   A0A1U7U9S9   A0A024R5X2   Q9Y6N5   A0A3P8U9Y8  

EC Number

1.8.5.-

Pubmed

19121390    22118469    26354079    28004739    18362917    19820115    + More
20075255    21292972    24508170    15489334    15057822    15632090    30249741    23236062    24438588    25186727    21551351    20010809    16341006    12364791    14747013    17210077    19892987    24813606    25244985    21993624    29451363    17554307    21804562    20920257    23761445    16141072    21183079    23576753    23542700    25830018    24487278    16136131    22722832    17975172    11181995    10224084    10810093    21269460    22852582    24275569    25944712   

EMBL

BABH01015090    BABH01015091    BABH01015092    NWSH01000689    PCG74766.1    AGBW02014713    + More
OWR41143.1    KQ460711    KPJ12695.1    GEZM01029788    JAV85928.1    ODYU01001709    SOQ38288.1    KQ971315    EEZ98752.1    AXCM01001682    GGMR01002195    MBY14814.1    ABLF02024989    GEDC01023111    GEDC01016060    GEDC01006153    GEDC01001269    JAS14187.1    JAS21238.1    JAS31145.1    JAS36029.1    AXCN02000238    GL732574    EFX75511.1    IACF01001087    LAB66808.1    GFXV01007971    MBW19776.1    GGFK01008874    MBW42195.1    BT078641    HACA01030284    ACO13065.1    CDW47645.1    GGFK01008891    MBW42212.1    DS231877    EDS42107.1    GFDL01008109    JAV26936.1    KK107503    EZA49605.1    AABR07053581    BC158559    CH473949    AAI58560.1    EDL80049.1    GANO01003027    JAB56844.1    QOIP01000006    RLU21349.1    AEYP01028467    AEYP01028468    AEYP01028469    AEYP01028470    AEYP01028471    AEYP01028472    AEYP01028473    GDHF01031117    JAI21197.1    GDHF01029255    JAI23059.1    JP018768    AES07366.1    ATLV01019037    KE525259    KFB43524.1    GFDF01001881    JAV12203.1    ACTA01057171    ACTA01065171    ACTA01073171    AAEX03016100    AAEX03016101    AERX01010892    APCN01002123    AAAB01008879    EAA08424.5    HAAF01000606    CCP72432.1    AEMK02000004    AK313111    BAG35933.1    AYCK01024451    GGFL01006670    MBW70848.1    AAPE02011751    AAPE02011752    AAPE02011753    GFDF01001882    JAV12202.1    JH000507    EGV93660.1    ADMH02001615    ETN61782.1    AF174535    AK008290    AK075598    AL928950    BC011153    GGFL01003322    MBW67500.1    GABC01010099    JAA01239.1    AAGW02024642    AAGW02024643    CM012442    RVE71699.1    GBXI01016039    JAC98252.1    GCES01146632    JAQ39690.1    AACZ04064526    GABF01006199    GABD01000838    GABE01005383    JAA15946.1    JAA32262.1    JAA39356.1    AJFE02111342    AJFE02111343    AJFE02111344    AANG04001761    CH471082    EAW77324.1    AF042284    AF151802    BC016836   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000007266    UP000075883    + More
UP000002358    UP000007819    UP000248481    UP000075886    UP000245341    UP000000305    UP000075900    UP000265020    UP000002320    UP000053097    UP000007646    UP000002494    UP000095300    UP000075880    UP000075881    UP000286642    UP000279307    UP000261480    UP000261500    UP000000715    UP000245340    UP000030765    UP000261580    UP000286640    UP000005226    UP000008912    UP000075885    UP000248482    UP000242638    UP000002254    UP000005207    UP000286641    UP000075840    UP000007062    UP000075903    UP000008227    UP000002281    UP000264840    UP000261680    UP000291021    UP000261460    UP000265100    UP000265160    UP000028760    UP000076408    UP000001074    UP000261560    UP000265040    UP000081671    UP000265200    UP000001038    UP000001075    UP000233160    UP000000673    UP000000589    UP000265180    UP000002852    UP000001811    UP000007635    UP000265000    UP000265120    UP000002277    UP000240080    UP000011712    UP000189704    UP000005640    UP000265080   

PRIDE

H9JC91    E2QTQ8    I3JNW4    B2R7T6    G3HMD2    Q9R112    + More
Q9Y6N5   

Pfam

PF07992   Pyr_redox_2        + More
PF04820   Trp_halogenase

Interpro

IPR015904   Sulphide_quinone_reductase        + More
IPR023753   FAD/NAD-binding_dom       
IPR036188   FAD/NAD-bd_sf       
IPR006905   Flavin_halogenase       

SUPFAM

SSF51905   SSF51905       

Gene 3D

3.50.50.60    

ProteinModelPortal

H9JC91   A0A2A4JSL8   A0A212EI09   A0A0N1PIL3   A0A1Y1MLF7   A0A2H1VBR8   + More
D6WBW8   A0A182MF88   A0A2S2NC75   K7ITL0   J9K3J1   A0A1B6EDK7   A0A2Y9HII5   A0A182Q5Z9   A0A2U3X809   E9GXZ9   A0A2P2HYF4   A0A2H8TZS5   A0A182RYB8   A0A2M4AN29   C1BVL2   A0A2M4ANA4   A0A3Q2CNB5   B0WB42   A0A1Q3FHA1   A0A026W0M0   G3T2B9   B0BMT9   U5ER07   A0A1I8Q6U3   A0A182J8G8   A0A182K873   A0A3Q7WMN3   A0A3L8DN89   A0A3B3XGH5   A0A3B3U2B8   M3YIB5   A0A0K8U3B6   A0A0K8U8S2   G9KR37   A0A2U3ZP87   A0A084VZY0   A0A3Q4GBD8   A0A1L8E0E0   A0A3Q7S5U2   H2TPY3   G1M1P3   A0A182PTM6   A0A2Y9L9M2   A0A3P9PNL2   E2QTQ8   I3JNW4   A0A3Q7RHH5   A0A182HJ34   Q7QBJ7   A0A1Y9IRX1   U6CRH4   A0A286ZL94   F6Y205   A0A3Q3CHS0   A0A384BI12   B2R7T6   A0A3B4GZ10   A0A3P8NXK9   A0A3P9B7C1   A0A087XD32   A0A182XVJ5   A0A2M4D198   G1P4X2   A0A3B3C5G1   A0A3Q1JZ42   A0A1S3EP62   A0A3P9H957   H2LK25   A0A1L8E0V8   G3HMD2   A0A2K6EYL3   H2TPY4   W5JBD9   Q9R112   A0A3P9KR36   M3ZZ68   A0A1S4F0P9   A0A2M4CQ95   K7AI60   G1T782   A0A3S2MB41   G3NSH9   A0A0A1WIQ4   G3NSH3   A0A146P8J3   A0A3Q1IMN3   A0A3P8W6E5   H2Q9D6   A0A2R9CMM4   M3W7Y3   A0A1U7U9S9   A0A024R5X2   Q9Y6N5   A0A3P8U9Y8  

PDB

6MP5     E-value=2.55962e-113,     Score=1046

KEGG

101740027    K22470 eukaryotic sulfide quinone oxidoreductase [EC:1.8.5.8] | (RefSeq) sulfide:quinone oxidoreduct

PATHWAY

00920    Sulfur metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016491   GO:0070224   GO:0070221   GO:0071949   GO:0005743   GO:0005739   GO:0048038   GO:0070813   GO:0016021   GO:0008270   GO:0051539   GO:0003677   GO:0006284   GO:0003906   GO:0005634   GO:0006285   GO:0019104   GO:0003824   GO:0055114  

PANTHER

PTHR10632  

Subcellular location

Mitochondrion  

Length:

440

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.07694

Exp number, first 60 AAs:

0.06453

Total prob of N-in:

0.00617

outside

1  -  440

 

 

Pi

24.392646

Theta

22.825293

Tajima's D

0.677308

CLR

0.000861

CSRT

0.577921103944803

Interpretation

Uncertain