Gene

KWMTBOMO10499

Pre Gene Modal

BGIBMGA006990

Annotation

ryanodine_receptor-like_protein_[Danaus_plexippus]

Location

Bomo_Chr17(-):12870893-12887283      View in EpiBrowser

Full name

Protein snakeskin      

Location in the cell

PlasmaMembrane   Reliability : 4.351

CDS

ATGGTTTCCGTTCAGACTATAGCGACTATAGTCGTGAAGACATTCAAAATTGTCTTGAACATTATAATCTTAGTGCTCTACCGCACCGGTTACAATGGAGAGTTCCTGGGGGTCGGAGGAACTTGGAACCTGAACGAGGAGAAGAATCCTGACGCGGAGATCGTTGCCTCAGGAGTAATCGTGGGCTACCTCATTTATACGCTAGTGCAGATCGTCACATTCTTGTTTGGTACCACGGAGCACAAACGCGCTTTGTCTGAGATCGTGATGAACTTCGTCGGAGTGTTCCTATGGATTGCGGTGGGCGCTGTGGCATTACACTACTGGGGAGGATACCAGGGCGAGCACCAGTTCCAGTTTGTCTTCGCTGAGAAACAGGTTGGCCTGGCCGTCGGAGCTCTATGCGTCATAAATGGAGCCATATATTTATTGGACACGGCACTTTCTGTCATACATTTCACAAAGGAAATGTAA

Protein

MVSVQTIATIVVKTFKIVLNIIILVLYRTGYNGEFLGVGGTWNLNEEKNPDAEIVASGVIVGYLIYTLVQIVTFLFGTTEHKRALSEIVMNFVGVFLWIAVGAVALHYWGGYQGEHQFQFVFAEKQVGLAVGALCVINGAIYLLDTALSVIHFTKEM

Description

Required for assembly of smooth septate junctions (sSJs). May be important for barrier function of the midgut epithelium.
Required for assembly of smooth septate junctions (sSJs), together with mesh and Tsp2A (PubMed:22854041, PubMed:26848177). May be important for barrier function of the midgut epithelium.

Subunit

Forms a complex with Tsp2A and mesh (PubMed:26848177). Interacts with mesh; the interaction may be necessary for the localization of both proteins to the cell apicolateral region (PubMed:22854041).

Keywords

Cell junction   Cell membrane   Complete proteome   Direct protein sequencing   Membrane   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Protein snakeskin

Uniprot

H9JBU5   A0A2H1V6X4   A0A2A4JGU3   A0A212EUW1   A0A1D5RMU7   A0A194PI55   + More
A8C9Z3   A0A1L8DJL8   A0A1B0GL15   E9J7N8   A0A1Q3FMB6   A0A1Q3FLV3   A0A1W4XN22   A0A1B6HMV8   A0A1B6L527   A0A1B6FGC7   A0A0L7LGW8   A0A067QYM7   T1PAC6   A0A1B6ELH2   A0A182KCR6   A0A1B0G911   A0A1A9Y043   A0A1A9UQR6   A0A1A9Z2Y7   A0A1A9WRH7   A0A2J7QHB5   A0A0C9R279   A0A182IQH7   A0A0A1XJB2   A0A1B1ZGG5   A0A182QIU4   A0A182LUW7   A0A182VLD6   Q7QDX7   A0A182HXD7   A0A182LND7   A0A182YIT5   A0A182FBV4   A0A084VUP8   T1DKF2   W8C7U8   E2ASU3   A0A182RJS8   W5JJV6   B4MKW3   A0A1Y1LLN1   B4LG14   B3NE42   B4IYP9   A0A182NDF8   B4KV85   A0A0J7K5N8   Q17HS5   A0A182PLU4   A0A1W4VU80   B4PFD8   A0APU7   C0MKE7   Q9VW87   A0A182X1N6   A0A3B0JRD9   A0A182W3X0   A0A182SUE3   A0A026X5F3   A0A1J1IGG0   B4IA52   A0A195BLG1   A0A158NLP9   A0A1S4F265   B3M4P7   A0A232F5E7   B4ITJ5   Q2M0X4   B4GQZ0   B0WA98   C4WUQ0   K7JHR0   A0A087ZXG6   A0A151WK34   A0A2P8ZPA6   A0A195FVQ8   A0A336M3J5   A0A2S2PL14   J3JYN4   A0A170YLU5   D1GZ07   D1GYQ4   A0A151IAM1   A0A1B6D7J7   A0A1B0B3K6   A0A0L7QR41   A0A1L8EHS0   A0A0L0C0F2   D6WX16   A0A0K8UXH7   A0A034WLF9   A0A3Q0IZ88   A0A146M3W1  

Pubmed

22328496    15591204    22118469    19121390    26354079    17760985    + More
21282665    26227816    24845553    25315136    25830018    27464714    12364791    14747013    17210077    20966253    25244985    24438588    24495485    20798317    20920257    23761445    17994087    18057021    28004739    17510324    17550304    16951084    22936249    19126864    10731132    12537572    12537569    22854041    26848177    24508170    30249741    21347285    28648823    15632085    20075255    29403074    22516182    26108605    18362917    19820115    25348373    26823975   

EMBL

BABH01015024    ODYU01000980    SOQ36549.1    NWSH01001534    PCG70938.1    AGBW02012291    + More
OWR45276.1    KQ459603    KPI93101.1    AJVK01015692    EU035817    ABV44719.1    GFDF01007438    JAV06646.1    AJWK01034052    GL768590    EFZ11159.1    GFDL01006402    JAV28643.1    GFDL01006445    JAV28600.1    GECU01031702    JAS76004.1    GEBQ01021246    GEBQ01008502    JAT18731.1    JAT31475.1    GECZ01029451    GECZ01027120    GECZ01021632    GECZ01020507    GECZ01002767    JAS40318.1    JAS42649.1    JAS48137.1    JAS49262.1    JAS67002.1    JTDY01001181    KOB74629.1    KK853186    KDR10074.1    KA645687    AFP60316.1    GECZ01031026    JAS38743.1    CCAG010002958    NEVH01013984    PNF27966.1    GBYB01006942    JAG76709.1    GBXI01003250    JAD11042.1    KU562965    ANX99820.1    AXCN02002123    AXCM01000309    AAAB01008849    EAA07189.3    APCN01005181    ATLV01016979    KE525139    KFB41692.1    GAMD01000961    JAB00630.1    GAMC01000317    JAC06239.1    GL442359    EFN63518.1    ADMH02001310    ETN63059.1    CH963847    EDW72888.1    KRF97650.1    GEZM01056124    JAV72835.1    CH940647    EDW70413.1    CH954178    EDV52466.1    CH916366    EDV96586.1    CH933809    EDW19425.1    LBMM01013146    KMQ85798.1    CH477246    EAT46164.1    CM000159    EDW95224.1    AM294685    CM000363    CM002912    CAL26671.1    EDX11186.1    KMZ00695.1    AM294673    AM294674    AM294675    AM294676    AM294677    AM294678    AM294679    AM294680    AM294681    AM294682    AM294683    AM294684    FM245818    FM245819    FM245820    FM245821    FM245822    FM245823    FM245824    FM245825    FM245826    FM245827    FM245828    FM245829    CAL26659.1    CAL26660.1    CAL26661.1    CAL26662.1    CAL26663.1    CAL26664.1    CAL26665.1    CAL26666.1    CAL26667.1    CAL26668.1    CAL26669.1    CAL26670.1    CAR93744.1    CAR93745.1    CAR93746.1    CAR93747.1    CAR93748.1    CAR93749.1    CAR93750.1    CAR93751.1    CAR93752.1    CAR93753.1    CAR93754.1    CAR93755.1    AE014296    AY052037    BT122195    AAK93461.1    ADE60669.1    OUUW01000009    SPP84704.1    KK107019    QOIP01000007    EZA62654.1    RLU20887.1    CVRI01000048    CRK98858.1    CH480826    EDW44165.1    KQ976450    KYM85642.1    ADTU01019629    CH902618    EDV39446.1    NNAY01000965    OXU25700.1    CH891711    EDW99708.1    CH379069    EAL30802.1    CH479188    EDW40175.1    DS231870    EDS40988.1    ABLF02037977    AK341164    BAH71620.1    KQ983020    KYQ48218.1    PYGN01000005    PSN58310.1    KQ981219    KYN44392.1    UFQS01000099    UFQS01000360    UFQT01000099    UFQT01000360    SSW99469.1    SSX23503.1    GGMR01017532    MBY30151.1    BT128363    AEE63321.1    GEMB01003174    JAS00037.1    FN546746    CBE67045.1    FN546643    FN546644    FN546645    FN546646    FN546647    FN546648    FN546649    FN546650    FN546651    FN546652    FN546653    FN546654    CBE66942.1    CBE66943.1    CBE66944.1    CBE66945.1    CBE66946.1    CBE66947.1    CBE66948.1    CBE66949.1    CBE66950.1    CBE66951.1    CBE66952.1    CBE66953.1    KQ978186    KYM96560.1    GEDC01025853    GEDC01015753    JAS11445.1    JAS21545.1    JXJN01007886    KQ414784    KOC61029.1    GFDG01000594    JAV18205.1    JRES01001072    KNC25778.1    KQ971361    EFA08057.1    GDHF01020937    JAI31377.1    GAKP01003967    GAKP01003966    JAC54985.1    GDHC01004674    JAQ13955.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000092462    UP000092461    + More
UP000192223    UP000037510    UP000027135    UP000095301    UP000075881    UP000092444    UP000092443    UP000078200    UP000092445    UP000091820    UP000235965    UP000075880    UP000075886    UP000075883    UP000075903    UP000007062    UP000075840    UP000075882    UP000076408    UP000069272    UP000030765    UP000000311    UP000075900    UP000000673    UP000007798    UP000008792    UP000008711    UP000001070    UP000075884    UP000009192    UP000036403    UP000008820    UP000075885    UP000192221    UP000002282    UP000000304    UP000000803    UP000076407    UP000268350    UP000075920    UP000075901    UP000053097    UP000279307    UP000183832    UP000001292    UP000078540    UP000005205    UP000007801    UP000215335    UP000001819    UP000008744    UP000002320    UP000007819    UP000002358    UP000005203    UP000075809    UP000245037    UP000078541    UP000078542    UP000092460    UP000053825    UP000037069    UP000007266    UP000079169   

PRIDE

Q9VW87   

Interpro

IPR038976   Ssk       

ProteinModelPortal

H9JBU5   A0A2H1V6X4   A0A2A4JGU3   A0A212EUW1   A0A1D5RMU7   A0A194PI55   + More
A8C9Z3   A0A1L8DJL8   A0A1B0GL15   E9J7N8   A0A1Q3FMB6   A0A1Q3FLV3   A0A1W4XN22   A0A1B6HMV8   A0A1B6L527   A0A1B6FGC7   A0A0L7LGW8   A0A067QYM7   T1PAC6   A0A1B6ELH2   A0A182KCR6   A0A1B0G911   A0A1A9Y043   A0A1A9UQR6   A0A1A9Z2Y7   A0A1A9WRH7   A0A2J7QHB5   A0A0C9R279   A0A182IQH7   A0A0A1XJB2   A0A1B1ZGG5   A0A182QIU4   A0A182LUW7   A0A182VLD6   Q7QDX7   A0A182HXD7   A0A182LND7   A0A182YIT5   A0A182FBV4   A0A084VUP8   T1DKF2   W8C7U8   E2ASU3   A0A182RJS8   W5JJV6   B4MKW3   A0A1Y1LLN1   B4LG14   B3NE42   B4IYP9   A0A182NDF8   B4KV85   A0A0J7K5N8   Q17HS5   A0A182PLU4   A0A1W4VU80   B4PFD8   A0APU7   C0MKE7   Q9VW87   A0A182X1N6   A0A3B0JRD9   A0A182W3X0   A0A182SUE3   A0A026X5F3   A0A1J1IGG0   B4IA52   A0A195BLG1   A0A158NLP9   A0A1S4F265   B3M4P7   A0A232F5E7   B4ITJ5   Q2M0X4   B4GQZ0   B0WA98   C4WUQ0   K7JHR0   A0A087ZXG6   A0A151WK34   A0A2P8ZPA6   A0A195FVQ8   A0A336M3J5   A0A2S2PL14   J3JYN4   A0A170YLU5   D1GZ07   D1GYQ4   A0A151IAM1   A0A1B6D7J7   A0A1B0B3K6   A0A0L7QR41   A0A1L8EHS0   A0A0L0C0F2   D6WX16   A0A0K8UXH7   A0A034WLF9   A0A3Q0IZ88   A0A146M3W1  

KEGG

101737793    no KO assigned | (RefSeq) uncharacterized LOC101737793

GO

GO:0016327   GO:0019991   GO:0005918   GO:0016021   GO:0005887   GO:0061028   GO:0005920   GO:0060576   GO:0007496  

PANTHER

PTHR36692  

Subcellular location

Apicolateral cell membrane   Specific to smooth septate junctions.   With evidence from 1 publications.
Cell junction   Specific to smooth septate junctions.   With evidence from 1 publications.
Septate junction   Specific to smooth septate junctions.   With evidence from 1 publications.

Length:

157

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

90.08884

Exp number, first 60 AAs:

28.837

Total prob of N-in:

0.99253

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  29

outside

30  -  53

TMhelix

54  -  76

inside

77  -  87

TMhelix

88  -  110

outside

111  -  129

TMhelix

130  -  152

inside

153  -  157

 

 

Pi

251.80411

Theta

163.00117

Tajima's D

1.20989

CLR

0.864235

CSRT

0.712014399280036

Interpretation

Uncertain