Gene

KWMTBOMO10493  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007114

Annotation

eukaryotic_translation_initiation_factor_3_subunit_B_[Bombyx_mori]

Location

Bomo_Chr17(+):12509957-12517334      View in EpiBrowser

Full name

Eukaryotic translation initiation factor 3 subunit B      

Alternative Name

Eukaryotic translation initiation factor 3 subunit 9

Location in the cell

Cytoplasmic   Reliability : 2.854

CDS

ATGGCTAAGAAAAAAGGCGATGAAAAAGCGAATCCAGCTCCTCAAAGTGACAATGAGGAACAGAACTTTGAAGAAGAACCTGATTTTGACGACCCAGAGGATTTCGTAGAGATTCCTGAAGAAGAATTATTGGCGGATATCTTAGAACAGAAGCCTAAGGAATCTGACGGTTATGAAAACGTTGTAGTCGTAGACGGGTGTCCGCAGGTCGGCCCCGAGCGTCTTGAGAAACTACAGAGCGTTATAAACAAAATATTTAGTAAATTCGGTAAAATAGTCAACGAATACTACCCCACGACTGAGAATGGACTCACGACTGGGTACATTTTCCTGGAATACAGTAACCCCCAGAATGCCGCCGAAGCCGTGAAAGCGACGAACAACTGTAAATTAGATAAACAACACACATTTTTAGTGAATCTTTTCACGGACTTTCAAAAGTATTCAGATATTCCTAAAGAATGGGAGCCACCGGCACCTCAACCATTCAAGGTGCAGTCAGATCTGCAATGGTATTTAATGGATCCTGATGCATATGACCAGTTCCTTGTTGGCATTGGGACTGGTGTGGCTCTCCAGGTGTGGCAGAATGCATTACCTGAACCCCTGCTGTTACAGGAGAGACCAAACTGGACCGAAACCTATGCCGTCTGGTCACCTTTAGGAACATACTTAGCAACTTTCCACTGGCGAGGTGTAGCACTATGGGCTGGTCCAAAGTTCTCACAATTCCAGAAGTTTTTCCACCCTGAAGCTAGGTTTATATCATTTTCTCCATGTGAGAACTACATTGTGACGTTTTCACCTAGTGGTGACAGAGGAGATGACAAGAAATTGATTATTTGGGATATTAGAACTGGTCAAGAGAAACGTAGTTTCCCACCTCCTGATGAGTATGTTACCTGGCCTATTTTCCGTTGGAGTAAAGATGACAGGTTCTTCGCCAGAATTGGAGCTGATGTTCTCTCTGTATATGAGACTCCAGGTTTTGGGCTACTTGATAAGAAATCAATTAAAATACCTGGAATTAGAGACTTCAGTTGGTCTCCATCAGATAATACTCTAGCCTACTGGGTAGCTGAAGACAAGGATGTTCCTGCCAGAGTAACACTCTTGGAAATCCCCAATCGTACTGAAGTTCGTTCCAAAAACTTGTTTTCGGTGGCTGACTGTAAAATTCATTGGCAGAAGAGCGGAGACTACTTGTGCGTAAAAGTAGATCGTTACTCTAAAGTGAAGAAAGATAAGATTGATATTAAATACTCTGGAATGTATTATAATTTCGAGATCTTCCATATGAGGGAAAAGGAAATTCCTGTAGATTCCGTCGAGATCAAGGAACCTATCCAGGCTTTTGCTTGGGAGCCAGTTGGGTCAAAGTTCTCTATTATTCACGGTGACCCAGCAAACATCAGTATCAGCTTCTATCAAGTAAATACTGGCCAAGCACCTACATTGCTCAAGAAGTTCGAGAGGAAGCCATTCAACCATCTTTTCTGGTCACCATCTGGGCAGTTCATTGTCCTGGCCAACCTTGGACTGACTGGTGGTGCATTGGAGTTCTTGGACACAAATGACTTTACCATTATGAATGTGGCTGATCATTATCAGATGTCTGGGATCGAATGGGATCCAACAGGACGCTATGTAGTGACTGGTGTGTCTTCGCTCAAATGTAAAATGGATTGCGGCTATTACATCTGGTCATTCCAGGGCAAGATACTCAGGAGAGTGATGAAGGAAGGTTTCGCGCAGTTCCACTGGAGGCCCCGTCCACCGACGCTGCTCTCTGAGAAGCAACAGAAAGAGATCAAGAAGAATCTTAAGAAATACTACTCGCAATTCGAGTCTAAAGATCGTATGCGCAGTAGCAAAGCCAGCAAGGAACTGGTGGCTAAGCGTACTGAGCAGATGAAGAAGTTCACGGAGTACCGTGAGTCTAAGATCCAGGAATGGAACGAGCAGAAGCCGCGCCGGCTCGAACTTAGAGATTATGTAGACACAGACGGTCTTGACACGGATGCGGTGAATACAGTCGAAGAGGTTATTGAATTTTTCGTGAAAGAGGAACAAACCGTCATCGAGTAG

Protein

MAKKKGDEKANPAPQSDNEEQNFEEEPDFDDPEDFVEIPEEELLADILEQKPKESDGYENVVVVDGCPQVGPERLEKLQSVINKIFSKFGKIVNEYYPTTENGLTTGYIFLEYSNPQNAAEAVKATNNCKLDKQHTFLVNLFTDFQKYSDIPKEWEPPAPQPFKVQSDLQWYLMDPDAYDQFLVGIGTGVALQVWQNALPEPLLLQERPNWTETYAVWSPLGTYLATFHWRGVALWAGPKFSQFQKFFHPEARFISFSPCENYIVTFSPSGDRGDDKKLIIWDIRTGQEKRSFPPPDEYVTWPIFRWSKDDRFFARIGADVLSVYETPGFGLLDKKSIKIPGIRDFSWSPSDNTLAYWVAEDKDVPARVTLLEIPNRTEVRSKNLFSVADCKIHWQKSGDYLCVKVDRYSKVKKDKIDIKYSGMYYNFEIFHMREKEIPVDSVEIKEPIQAFAWEPVGSKFSIIHGDPANISISFYQVNTGQAPTLLKKFERKPFNHLFWSPSGQFIVLANLGLTGGALEFLDTNDFTIMNVADHYQMSGIEWDPTGRYVVTGVSSLKCKMDCGYYIWSFQGKILRRVMKEGFAQFHWRPRPPTLLSEKQQKEIKKNLKKYYSQFESKDRMRSSKASKELVAKRTEQMKKFTEYRESKIQEWNEQKPRRLELRDYVDTDGLDTDAVNTVEEVIEFFVKEEQTVIE

Description

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Subunit

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

Similarity

Belongs to the eIF-3 subunit B family.

Keywords

Complete proteome   Cytoplasm   Initiation factor   Protein biosynthesis   Reference proteome   Repeat   RNA-binding   WD repeat   Coiled coil  

Feature

chain  Eukaryotic translation initiation factor 3 subunit B

Uniprot

H9JC69   Q1HDZ5   A0A1E1WD05   A0A194PPN6   A0A212FCN5   A0A2H1VIP1   + More
S4PXT3   I4DR57   A0A194QTJ7   D6WUK7   V5GI13   A0A067QVW9   A0A2J7RNI2   A0A0T6B6A9   A0A1Y1LS28   A0A2A3EMN5   A0A088AC80   A0A0M8ZND4   E2BS38   N6TPS4   F4X5V9   A0A151I409   A0A158NMF2   A0A195CEE1   A0A154P105   E2AAT2   A0A026X2Y6   A0A151WMT4   E9IEG7   A0A310SHS7   A0A0C9RX00   A0A023FAF8   R4G4W6   A0A0L7RF23   A0A069DWB4   A0A224X8C5   A0A0J7N3T4   A0A146KPL3   A0A151J3W5   R4WRQ2   K7J1X5   A0A0P5XMM9   A0A0P6FLL1   A0A0P6EE96   A0A0P6HM82   A0A0P5QNF4   A0A0P5I3L0   A0A0P6DH04   A0A0P4ZNW3   A0A0P5I2B7   A0A162QPL6   A0A0P5PZD6   A0A0P5AW21   A0A0P6DHD6   A0A0P5NLI8   A0A0P5IJ29   A0A2S2R1K5   A0A0P6GKQ8   A0A0P5NLN6   A0A0P6FRR4   E0VT87   A0A232F5V4   A0A0P5QZH4   A0A0P5NZ65   A0A0P5P8F7   A0A0N8BXA4   A0A151JVC3   A0A0P5REK0   A0A0P5NSF0   A0A0P4XUB1   A0A0N8B5D9   A0A0P5XKE3   A0A0P5M629   A0A0P5ISC1   E9HS20   A0A3G4R8Q3   J9JVT9   A0A0P5KUZ6   A0A2S2P3X7   A0A0P6FA82   A0A087TDL5   A0A0P4ZWV7   A0A0P5ATE7   A0A2R5LLP3   A0A293MYX2   A0A2L2Y0I8   A0A0P6GFW3   A0A0P5TSH3   A0A1Q3F4H3   L7M0F9   A0A2K7P6A9   Q0IEY3   A0A0P6FQL9   T1P7U6   U5EXZ0   A0A1Z5L7N1   A0A1I8N5V4   A0A224Z1X8   A0A131XCJ0  

Pubmed

19121390    26354079    22118469    23622113    22651552    18362917    + More
19820115    24845553    28004739    20798317    23537049    21719571    21347285    24508170    30249741    21282665    25474469    26334808    26823975    23691247    20075255    20566863    28648823    21292972    26561354    25576852    17510324    28528879    25315136    28797301    28049606   

EMBL

BABH01014979    DQ497202    GDQN01006186    JAT84868.1    KQ459603    KPI93095.1    + More
AGBW02009169    OWR51477.1    ODYU01002780    SOQ40698.1    GAIX01004488    JAA88072.1    AK404954    BAM20397.1    KQ461137    KPJ08848.1    KQ971357    EFA08366.2    GALX01004782    JAB63684.1    KK853186    KDR10090.1    NEVH01002540    PNF42396.1    LJIG01009551    KRT82854.1    GEZM01052629    JAV74376.1    KZ288210    PBC32950.1    KQ435970    KOX67810.1    GL450143    EFN81493.1    APGK01057007    KB741277    KB631850    ENN71245.1    ERL86710.1    GL888742    EGI58199.1    KQ976507    KYM82828.1    ADTU01020438    KQ977957    KYM98438.1    KQ434796    KZC05619.1    GL438172    EFN69461.1    KK107019    QOIP01000007    EZA62630.1    RLU20146.1    KQ982931    KYQ49212.1    GL762591    EFZ21042.1    KQ768478    OAD53140.1    GBYB01013605    JAG83372.1    GBBI01000723    JAC17989.1    ACPB03015836    GAHY01000401    JAA77109.1    KQ414608    KOC69435.1    GBGD01000689    JAC88200.1    GFTR01007799    JAW08627.1    LBMM01010607    KMQ87360.1    GDHC01021669    JAP96959.1    KQ980246    KYN17114.1    AK417377    BAN20592.1    GDIP01069899    JAM33816.1    GDIQ01046162    JAN48575.1    GDIQ01064605    JAN30132.1    GDIQ01025155    JAN69582.1    GDIQ01111837    JAL39889.1    GDIQ01224149    JAK27576.1    GDIQ01077391    JAN17346.1    GDIP01210974    JAJ12428.1    GDIQ01225396    JAK26329.1    LRGB01000311    KZS19851.1    GDIQ01128380    JAL23346.1    GDIP01207475    JAJ15927.1    GDIQ01077392    JAN17345.1    GDIQ01140572    JAL11154.1    GDIQ01215344    GDIQ01111838    JAK36381.1    GGMS01014662    MBY83865.1    GDIQ01044113    JAN50624.1    GDIQ01140573    JAL11153.1    GDIQ01044111    JAN50626.1    DS235760    EEB16593.1    NNAY01000853    OXU26201.1    GDIQ01108036    JAL43690.1    GDIQ01135828    JAL15898.1    GDIQ01138425    JAL13301.1    GDIQ01135827    JAL15899.1    KQ981706    KYN37426.1    GDIQ01108037    JAL43689.1    GDIQ01138426    JAL13300.1    GDIP01237827    JAI85574.1    GDIQ01211147    JAK40578.1    GDIP01083090    JAM20625.1    GDIQ01184199    JAK67526.1    GDIQ01211148    JAK40577.1    GL732744    EFX65461.1    MG993328    AYU58905.1    ABLF02036440    GDIQ01184198    JAK67527.1    GGMR01011554    GGMR01014469    MBY24173.1    MBY27088.1    GDIQ01050725    JAN44012.1    KK114737    KFM63204.1    GDIP01208619    JAJ14783.1    GDIP01208618    JAJ14784.1    GGLE01006232    MBY10358.1    GFWV01020978    MAA45706.1    IAAA01001338    LAA01702.1    GDIQ01046161    JAN48576.1    GDIP01123424    JAL80290.1    GFDL01012580    JAV22465.1    GACK01007677    JAA57357.1    CH477461    GDIQ01044112    JAN50625.1    KA644589    AFP59218.1    GANO01000695    JAB59176.1    GFJQ02003916    JAW03054.1    GFPF01012712    MAA23858.1    GEFH01003658    JAP64923.1   

Proteomes

UP000005204    UP000053268    UP000007151    UP000053240    UP000007266    UP000027135    + More
UP000235965    UP000242457    UP000005203    UP000053105    UP000008237    UP000019118    UP000030742    UP000007755    UP000078540    UP000005205    UP000078542    UP000076502    UP000000311    UP000053097    UP000279307    UP000075809    UP000015103    UP000053825    UP000036403    UP000078492    UP000002358    UP000076858    UP000009046    UP000215335    UP000078541    UP000000305    UP000007819    UP000054359    UP000008820    UP000095301   

PRIDE

H9JC69    Q1HDZ5    A0A088AC80    L7M0F9    Q0IEY3   

Pfam

PF08662   eIF2A        + More
PF00076   RRM_1

Interpro

IPR013979   TIF_beta_prop-like        + More
IPR011400   EIF3B       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR034363   eIF3B_RRM       
IPR000504   RRM_dom       
IPR035979   RBD_domain_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR036322   WD40_repeat_dom_sf       
IPR011990   TPR-like_helical_dom_sf       
IPR001680   WD40_repeat       

SUPFAM

SSF54928   SSF54928        + More
SSF48452   SSF48452       
SSF50978   SSF50978       

Gene 3D

2.130.10.10     3.30.70.330     1.25.40.10    

CDD

cd12278  RRM_eIF3B

ProteinModelPortal

H9JC69   Q1HDZ5   A0A1E1WD05   A0A194PPN6   A0A212FCN5   A0A2H1VIP1   + More
S4PXT3   I4DR57   A0A194QTJ7   D6WUK7   V5GI13   A0A067QVW9   A0A2J7RNI2   A0A0T6B6A9   A0A1Y1LS28   A0A2A3EMN5   A0A088AC80   A0A0M8ZND4   E2BS38   N6TPS4   F4X5V9   A0A151I409   A0A158NMF2   A0A195CEE1   A0A154P105   E2AAT2   A0A026X2Y6   A0A151WMT4   E9IEG7   A0A310SHS7   A0A0C9RX00   A0A023FAF8   R4G4W6   A0A0L7RF23   A0A069DWB4   A0A224X8C5   A0A0J7N3T4   A0A146KPL3   A0A151J3W5   R4WRQ2   K7J1X5   A0A0P5XMM9   A0A0P6FLL1   A0A0P6EE96   A0A0P6HM82   A0A0P5QNF4   A0A0P5I3L0   A0A0P6DH04   A0A0P4ZNW3   A0A0P5I2B7   A0A162QPL6   A0A0P5PZD6   A0A0P5AW21   A0A0P6DHD6   A0A0P5NLI8   A0A0P5IJ29   A0A2S2R1K5   A0A0P6GKQ8   A0A0P5NLN6   A0A0P6FRR4   E0VT87   A0A232F5V4   A0A0P5QZH4   A0A0P5NZ65   A0A0P5P8F7   A0A0N8BXA4   A0A151JVC3   A0A0P5REK0   A0A0P5NSF0   A0A0P4XUB1   A0A0N8B5D9   A0A0P5XKE3   A0A0P5M629   A0A0P5ISC1   E9HS20   A0A3G4R8Q3   J9JVT9   A0A0P5KUZ6   A0A2S2P3X7   A0A0P6FA82   A0A087TDL5   A0A0P4ZWV7   A0A0P5ATE7   A0A2R5LLP3   A0A293MYX2   A0A2L2Y0I8   A0A0P6GFW3   A0A0P5TSH3   A0A1Q3F4H3   L7M0F9   A0A2K7P6A9   Q0IEY3   A0A0P6FQL9   T1P7U6   U5EXZ0   A0A1Z5L7N1   A0A1I8N5V4   A0A224Z1X8   A0A131XCJ0  

PDB

6FEC     E-value=0,     Score=1798

KEGG

733052    K03253 translation initiation factor 3 subunit B | (RefSeq) eIF3-S9, eIF3b; eukaryotic translation i

PATHWAY

03013    RNA transport - Bombyx mori (domestic silkworm)

GO

GO:0016282   GO:0005852   GO:0003743   GO:0001732   GO:0033290   GO:0031369   GO:0006446   GO:0006413   GO:0016021   GO:0003676   GO:0000166   GO:0003723   GO:0005515   GO:0046872   GO:0003824  

PANTHER

PTHR14068  

Subcellular location

Cytoplasm  

Length:

695

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.805209999999999

Exp number, first 60 AAs:

0

Total prob of N-in:

0.02817

outside

1  -  695

 

 

Pi

227.943388

Theta

194.404468

Tajima's D

0.766116

CLR

0.408239

CSRT

0.587370631468427

Interpretation

Uncertain