Gene

KWMTBOMO10488  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007110

Annotation

small_G_protein_[Spodoptera_exigua]

Location

Bomo_Chr17(+):12388107-12436418      View in EpiBrowser

Full name

Ras-related protein Rac1      

Location in the cell

Mitochondrial   Reliability : 2.163

CDS

ATGGTAGATGGAAAGCCAATCAACTTGGGCCTCTGGGATACAGCCGGACAGGAAGACTACGATCGACTCCGCCCCCTCTCTTACCCACAGACGGACGTCTTCCTTATATGTTTTTCGCTGGTCAACCCAGCCTCATTCGAAAACGTTCGGGCCAAGTGGTATCCAGAAGTTCGGCATCACTGCCCGTCGACGCCCATCATCCTGGTCGGGACCAAGCTCGACTTACGCGAAGACAAGGACACCATTGAAAAGCTCAAGGACAAGAAACTAGCCCCGATCACCTACACGCAGGGTTTGGGCATGTCCAAGGAGATAAACGCTGTCAAGTATTTGGAGTGTTCAGCGCTGACGCAGAAGGGCCTGAAGACCGTGTTCGATGAGGCGATTCGCGCCGTGCTATGCCCGGTGCAGCCCATCAAGGGCCGGCGGCGGCATTACGTCGGAGCCGGTGTGCGCGTCAGAGCTCACACGAACATCCAACAACGCCGCGACACACAGCTAATGCGCCGTCAACCGGACCGCGATACGCACACGCAAACGTTAGCGCGCACCGCCCAACGATACGCGCGACGTAGCGGGGGTCGGTGTGTGTCAAGTCCCTAA

Protein

MVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLREDKDTIEKLKDKKLAPITYTQGLGMSKEINAVKYLECSALTQKGLKTVFDEAIRAVLCPVQPIKGRRRHYVGAGVRVRAHTNIQQRRDTQLMRRQPDRDTHTQTLARTAQRYARRSGGRCVSSP

Description

Involved in axon outgrowth and myoblast fusion. Plays a role in regulating dorsal closure during embryogenesis. Involved in integrin alpha-PS3/beta-nu-mediated phagocytosis of Gram-positive S.aureus by hemocytes.

Subunit

Interacts with Sra-1. Interacts (via REM 1 repeats) with Pkn (via N-terminus).

Similarity

Belongs to the small GTPase superfamily. Rho family.

Keywords

Cell membrane   Complete proteome   Developmental protein   GTP-binding   Lipoprotein   Membrane   Methylation   Nucleotide-binding   Phagocytosis   Prenylation   Reference proteome  

Feature

chain  Ras-related protein Rac1
propeptide  Removed in mature form

Uniprot

H9JC65   A0A2H1WNP9   J9R033   A0A059VBV6   S4PBQ2   A0A212FC00   + More
A0A1B6J1H1   A0A1B6GK94   A0A1B6KFE2   A0A1B6DHQ1   A0A1B6JFL9   A0A1B6KIP4   A0A2J7PK11   A0A067RGL0   A0A026WN95   A0A194PPN2   E9JCL1   A0A151J446   F4WFL0   A0A151HYZ1   A0A0J7KSS7   A0A195FT76   E2BW21   A0A158NSH9   E2AAI7   A0A3L8DX32   A0A195CS85   A0A151WI97   V9IKF9   A0A0B4J2M1   A0A194QTP8   A0A069DPS2   A0A224XXI4   A0A0V0GF40   A0A1W4WMW4   A0A0T6B0W7   A0A1Y1N9B9   A0A0P4VSZ1   R4G578   V5GPZ1   A0A2R7WKM6   A0A0A9W7K7   A0A232EZV3   A0A2S2NNV6   A0A1Q3EUE0   A0A1Q3EUF0   D6WGS1   U5EZ98   A0A1J1IBW5   T1DF58   A0A2H8TQX1   A0A0B4J2L1   A0A1L8DKW7   A0A1B0GP55   A0A240SY11   A0A023EIV8   A0A336LVN3   B3M528   E9FRC3   A0A0P5IN29   A0A1W4W6P4   B4LG76   B4L0N4   A0A3B0KG93   Q29EV6   M9PBH7   B4PD66   B4HVR1   B3NB87   B4QLZ5   P40792   V9KJF0   B4N547   B4J2E5   T1H4M0   A0A0P4WCW7   A0A0A7DNX4   Q16V02   A0A3B4DFS4   A0A0P5BPF4   E0VNS7   A0A0M4EC54   A0A1A9UM17   A0A1B0BPU5   A0A1A9ZDN7   A0A1A9WLH6   D3TPD8   A0A3Q2YCX2   A0A165VGD1   A0A0K8TRV5   A0A0L0BT07   A0A3L8SG90   A0A0K8UUK4   A0A034VM04   A0A0A1X180   W8C7L8   A0A0P5DW07   A0A2P4SVU0   A0A0P4WK26  

Pubmed

19121390    23660478    24866850    23622113    22118469    24845553    + More
24508170    26354079    21282665    21719571    20798317    21347285    30249741    26334808    28004739    27129103    25401762    26823975    28648823    18362917    19820115    24330624    24945155    17994087    21292972    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17550304    22936249    7958857    7835340    7720592    12537569    10323867    12818175    17507675    22547074    24402279    26091106    17510324    20566863    20353571    26369729    26108605    30282656    25348373    25830018    24495485   

EMBL

BABH01014970    BABH01014971    ODYU01009919    SOQ54658.1    JX392403    AFR31806.1    + More
KJ547699    AHZ89303.1    GAIX01004501    JAA88059.1    AGBW02009256    OWR51248.1    GECU01014694    JAS93012.1    GECZ01025398    GECZ01019608    GECZ01009546    GECZ01006895    JAS44371.1    JAS50161.1    JAS60223.1    JAS62874.1    GEBQ01030073    JAT09904.1    GEDC01012092    JAS25206.1    GECU01009739    JAS97967.1    GEBQ01028664    JAT11313.1    NEVH01024942    PNF16674.1    KK852652    KDR19393.1    KK107161    EZA56574.1    KQ459603    KPI93090.1    GL771848    EFZ09442.1    KQ980211    KYN17208.1    GL888120    EGI66987.1    KQ976719    KYM76748.1    LBMM01003504    KMQ93452.1    KQ981276    KYN43507.1    GL451091    EFN80053.1    ADTU01024932    GL438128    EFN69534.1    QOIP01000003    RLU24793.1    KQ977329    KYN03556.1    KQ983089    KYQ47572.1    JR048909    AEY60799.1    KQ461137    KPJ08842.1    GBGD01003074    JAC85815.1    GFTR01003196    JAW13230.1    GECL01000226    JAP05898.1    LJIG01016368    KRT80811.1    GEZM01012962    JAV92846.1    GDKW01000980    JAI55615.1    ACPB03024203    ACPB03024204    GAHY01000745    JAA76765.1    GALX01004794    JAB63672.1    KK854893    PTY19550.1    GBHO01041136    GBRD01007833    GDHC01017022    GDHC01005035    JAG02468.1    JAG57988.1    JAQ01607.1    JAQ13594.1    NNAY01001454    OXU23922.1    GGMR01006198    MBY18817.1    GFDL01016122    JAV18923.1    GFDL01016123    JAV18922.1    KQ971327    EFA01250.1    GANO01001179    JAB58692.1    CVRI01000047    CRK97775.1    GALA01000772    JAA94080.1    GFXV01004789    MBW16594.1    ABLF02036916    GFDF01007067    JAV07017.1    AJVK01014983    AJWK01000190    AJWK01000191    GAPW01004699    GAPW01004698    JAC08900.1    UFQT01000140    SSX20759.1    CH902618    EDV39507.1    GL732523    EFX90140.1    GDIQ01210423    GDIP01100516    LRGB01002066    JAK41302.1    JAM03199.1    KZS09450.1    CH940647    EDW69384.1    CH933809    EDW18111.1    OUUW01000009    SPP84756.1    CH379070    EAL29953.1    AE014296    AGB93942.1    CM000159    EDW92814.1    CH480817    EDW50026.1    CH954178    EDV50140.1    CM000363    CM002912    EDX08781.1    KMY96784.1    U11823    L38309    Z35642    AY060408    JW865573    AFO98090.1    CH964101    EDW79486.1    CH916366    EDV96004.1    CAQQ02374471    GDRN01049507    JAI66549.1    KF907314    AIU99814.1    CH477607    EAT38364.1    GDIP01185655    JAJ37747.1    DS235346    EEB15033.1    CP012525    ALC42946.1    JXJN01018235    CCAG010005268    EZ423290    ADD19566.1    KT984816    AMZ00368.1    GDAI01000712    JAI16891.1    JRES01001407    KNC23156.1    QUSF01000022    RLW01441.1    GDHF01021972    JAI30342.1    GAKP01014601    JAC44351.1    GBXI01009641    JAD04651.1    GAMC01003544    GAMC01003543    JAC03012.1    GDIP01150411    JAJ72991.1    PPHD01020390    POI28203.1    GDRN01049506    JAI66550.1   

Proteomes

UP000005204    UP000007151    UP000235965    UP000027135    UP000053097    UP000053268    + More
UP000078492    UP000007755    UP000078540    UP000036403    UP000078541    UP000008237    UP000005205    UP000000311    UP000279307    UP000078542    UP000075809    UP000005203    UP000053240    UP000192223    UP000015103    UP000215335    UP000007266    UP000183832    UP000007819    UP000092462    UP000092461    UP000007801    UP000000305    UP000076858    UP000192221    UP000008792    UP000009192    UP000268350    UP000001819    UP000000803    UP000002282    UP000001292    UP000008711    UP000000304    UP000007798    UP000001070    UP000015102    UP000079169    UP000008820    UP000261440    UP000009046    UP000092553    UP000078200    UP000092460    UP000092445    UP000091820    UP000092444    UP000264820    UP000037069    UP000276834   

PRIDE

H9JC65    M9PBH7    P40792   

Pfam

PF00071   Ras

Interpro

IPR001806   Small_GTPase        + More
IPR027417   P-loop_NTPase       
IPR005225   Small_GTP-bd_dom       
IPR003578   Small_GTPase_Rho       

SUPFAM

SSF52540   SSF52540       

ProteinModelPortal

H9JC65   A0A2H1WNP9   J9R033   A0A059VBV6   S4PBQ2   A0A212FC00   + More
A0A1B6J1H1   A0A1B6GK94   A0A1B6KFE2   A0A1B6DHQ1   A0A1B6JFL9   A0A1B6KIP4   A0A2J7PK11   A0A067RGL0   A0A026WN95   A0A194PPN2   E9JCL1   A0A151J446   F4WFL0   A0A151HYZ1   A0A0J7KSS7   A0A195FT76   E2BW21   A0A158NSH9   E2AAI7   A0A3L8DX32   A0A195CS85   A0A151WI97   V9IKF9   A0A0B4J2M1   A0A194QTP8   A0A069DPS2   A0A224XXI4   A0A0V0GF40   A0A1W4WMW4   A0A0T6B0W7   A0A1Y1N9B9   A0A0P4VSZ1   R4G578   V5GPZ1   A0A2R7WKM6   A0A0A9W7K7   A0A232EZV3   A0A2S2NNV6   A0A1Q3EUE0   A0A1Q3EUF0   D6WGS1   U5EZ98   A0A1J1IBW5   T1DF58   A0A2H8TQX1   A0A0B4J2L1   A0A1L8DKW7   A0A1B0GP55   A0A240SY11   A0A023EIV8   A0A336LVN3   B3M528   E9FRC3   A0A0P5IN29   A0A1W4W6P4   B4LG76   B4L0N4   A0A3B0KG93   Q29EV6   M9PBH7   B4PD66   B4HVR1   B3NB87   B4QLZ5   P40792   V9KJF0   B4N547   B4J2E5   T1H4M0   A0A0P4WCW7   A0A0A7DNX4   Q16V02   A0A3B4DFS4   A0A0P5BPF4   E0VNS7   A0A0M4EC54   A0A1A9UM17   A0A1B0BPU5   A0A1A9ZDN7   A0A1A9WLH6   D3TPD8   A0A3Q2YCX2   A0A165VGD1   A0A0K8TRV5   A0A0L0BT07   A0A3L8SG90   A0A0K8UUK4   A0A034VM04   A0A0A1X180   W8C7L8   A0A0P5DW07   A0A2P4SVU0   A0A0P4WK26  

PDB

5FI0     E-value=1.09891e-73,     Score=700

KEGG

101736734    K04392 Ras-related C3 botulinum toxin substrate 1 | (RefSeq) ras-related protein Rac1

PATHWAY

04013    MAPK signaling pathway - fly - Bombyx mori (domestic silkworm)
04145    Phagosome - Bombyx mori (domestic silkworm)
04310    Wnt signaling pathway - Bombyx mori (domestic silkworm)
04933    AGE-RAGE signaling pathway in diabetic complications - Bombyx mori (domestic silkworm)

GO

GO:0005525   GO:0003924   GO:0007264   GO:0016021   GO:0016477   GO:0007266   GO:0008045   GO:0030036   GO:0005737   GO:0019901   GO:0031410   GO:0042995   GO:0005886   GO:0046843   GO:0016028   GO:0007394   GO:0019897   GO:0007419   GO:0007413   GO:0032147   GO:0050975   GO:0031532   GO:1902669   GO:0035011   GO:0097206   GO:0032794   GO:0035212   GO:0090303   GO:0007390   GO:0048010   GO:0007395   GO:0048814   GO:0010593   GO:0051491   GO:0007516   GO:0001954   GO:0007520   GO:0071902   GO:0009611   GO:0042052   GO:0045773   GO:0008258   GO:0008078   GO:0048615   GO:0035320   GO:0048675   GO:0051450   GO:0007298   GO:0007422   GO:1904059   GO:0030866   GO:0016199   GO:0030032   GO:0007613   GO:0071907   GO:0048747   GO:1903688   GO:0001726   GO:0007254   GO:0051017   GO:0007435   GO:0051963   GO:0008347   GO:0035099   GO:0016203   GO:0046664   GO:0016358   GO:0046330   GO:0007426   GO:0002433   GO:0034334   GO:0007411   GO:0008283   GO:0007391   GO:0030707   GO:0000902   GO:0007015   GO:0048813   GO:0005829   GO:0050770   GO:0048812   GO:0031175   GO:0050807   GO:0035010   GO:0007424   GO:0008237   GO:0005245   GO:0005891   GO:0004674   GO:0006418   GO:0003723   GO:0046872   GO:0003824  

Subcellular location

Cell membrane  

Length:

200

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0422

Exp number, first 60 AAs:

0.0422

Total prob of N-in:

0.03372

outside

1  -  200

 

 

Pi

213.017444

Theta

165.950648

Tajima's D

0.72361

CLR

0.380542

CSRT

0.581720913954302

Interpretation

Uncertain