Gene

KWMTBOMO10487

Pre Gene Modal

BGIBMGA006995

Annotation

MOF_protein_[Bombyx_mori]

Location

Bomo_Chr17(-):12382644-12384246      View in EpiBrowser

Full name

Histone acetyltransferase      

Transcription factor

MOZ_SAS

Location in the cell

Nuclear   Reliability : 3.367

CDS

ATGGCAAAAGGTGATAAAGAATTAGAGAAGCCAATAGTGAATAATGAGTTGCCTAATCCTGAGTGTCGAAGTACTGATAATGAAGACTCCGAGTCGGTCCCAGAACAGCCTTTGGACATAGGAGAACATTATTTAGTGCGGCGATCGGATGAGTCATGGCACCCGGCTGAGATTATACAGTCGCGATACAGTACAGCGGAATCTTGTTACGAATATTATGTCCATTATGTCGGATATGATAGAAGACTCGACGAATGGGTGTCCCGCCACCGGGTTATGTCAGATAGGTTCGACGTATGCGAGCAGTCGAACAATAACATAAACTGCGACCACCTGCTCACGGACAAATCCGGCCGGAAAATAACAAGGAATCAAAAACGTAAACATGACGAAATAAACCATGTGCAGAAAACTTACGCCGAAATGGATCCAACGACCGCCGCGCTTGAAAAGGAACATGAAGCTATTACTAAAGTTAAATACATAGACAGGATACAAATTGGAAAATATGAAATCGATACTTGGTATTTTAGTCCGTATCCTGATGAATATGGTAAACAATCAAAATTGTGGTTATGTGAATACTGTTTGAAGTATATGAGAATGGAAAAAACATACCGGTACCATCTCAGTGAATGCACAGCACGCCAACCCCAGGGTAACGAAATATACAGAAAAGGTACAATAGCTATTTTTGAAGCAGATGGCAAAGAACATAAAATATATTGTCAGAATTTGTGTTTATTAGCCAAATTATTTTTAGATCACAAAACCCTTTATTTTGATATAGAACAGTTTTTATTTTATATATTGTGTGAAGTTGACAAGCAAGGAGCTCACCTTGTAGGATATTTTTCAAAAGAAAAGGATTCACCTGAAGGCAATAATGTGGCATGTATATTGACTCTACCTCCATATCAGAGACAGGGGTATGGTAAACTCCTGATAGCTTTTAGTTATGAACTCTCAAGGCTCGAACAAGTTGTTGGAAGTCCAGAGAAGCCTTTATCAGATTTAGGCAAGTTAAGTTACAGATCGTACTGGTCATATGTTTTATTAGAAGTGTTAAGTGCTAGTAGAGGTACATTAAGTATCAAGGATTTAAGTCAGATGACAGGAATATCACAAACGGACATCATTTCAACTTTACAGTCAATGAACATGGTGAAGTACTGGAAAGGACAGCATGTTATTTGTGTTACACCTAAAATAGTTGCTGAACAATTAGCAAGCCCGCACTTTAAAAAACCACGGTTGTCAATAGATCCTTCAGCACTGAGATGGACGCCCCCTAGTAAACAGGGGAACTCTGCCAAAGCCAAAAAGTAG

Protein

MAKGDKELEKPIVNNELPNPECRSTDNEDSESVPEQPLDIGEHYLVRRSDESWHPAEIIQSRYSTAESCYEYYVHYVGYDRRLDEWVSRHRVMSDRFDVCEQSNNNINCDHLLTDKSGRKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYIDRIQIGKYEIDTWYFSPYPDEYGKQSKLWLCEYCLKYMRMEKTYRYHLSECTARQPQGNEIYRKGTIAIFEADGKEHKIYCQNLCLLAKLFLDHKTLYFDIEQFLFYILCEVDKQGAHLVGYFSKEKDSPEGNNVACILTLPPYQRQGYGKLLIAFSYELSRLEQVVGSPEKPLSDLGKLSYRSYWSYVLLEVLSASRGTLSIKDLSQMTGISQTDIISTLQSMNMVKYWKGQHVICVTPKIVAEQLASPHFKKPRLSIDPSALRWTPPSKQGNSAKAKK

Catalytic Activity

acetyl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-acetyl-L-lysyl-[protein]

Similarity

Belongs to the MYST (SAS/MOZ) family.

Feature

chain  Histone acetyltransferase

Uniprot

A5JPL6   A4K580   A0A2H1WNL7   A0A1E1W894   A0A0L7L2T3   A0A194QZ20   + More
A0A194PK37   A0A2J7QPU2   E2C6Q8   A0A026WZT6   A0A0C9PZ23   A0A151WVB7   E9IPR7   A0A154PHG8   A0A0L7QQJ7   A0A087ZR86   A0A310SAW0   E2A1K0   A0A1B6CN62   A0A151III6   A0A1B6L117   A0A0M9ABR3   A0A1W4XIV6   F4WNJ3   A0A195B8F6   A0A232EWM2   E0VL98   A0A195FXK8   A0A195EBX2   A0A2A3E5Y4   K7J356   K7WLT0   N6TF53   D6WHU4   A0A224XD32   A0A023F575   A0A069DUD7   A0A0V0G6Z5   A0A0N7Z8S8   E9GC17   A0A0N8BYH0   A0A0P5LH32   A0A0P5GH88   A0A0P6AM65   A0A0P5PVJ3   A0A164NB41   A0A0P5EG56   A0A0P5T1K5   A0A0P6IE21   A0A0P4XVK1   A0A0P4XZQ7   T1HIW2   A0A0P5DII3   A0A0A9VZK7   A0A3Q0ILL9   A0A2R7WQK2   T1J7N6   A0A0P6DZ38   A0A0P4YU28   V5HKI9   B7Q9K5   A0A0P6CXV2   A0A1E1XBR5   A0A3S3P3E0   A0A3R7PR76   A0A0N7ZC07   A0A2R5L9G8   A0A131XMD1   A0A2H8TFC8   X1WKV8   A0A2S2PKF7   A0A131YMS8   A0A293LHP2   A0A0P5SYK5   A0A224Z0K2   A0A1V9XCV5   A0A1Z5LCD9   A0A1S3J6A3   A0A210QA81   A0A1B6F6K3   T1L0F9   W5U8L4   H9GBU7   G1SH87   E2QT63   U3ES69   F1QX50   A0A2Y9I1F0   A0A067QV68   A9JTB7   K9ITZ6   F7B2S8   G3WE75   A0A2U3VQF6   A0A3Q7MRI4   M3VYT8   A0A2U3XEL0   A0A2Y9L7Y3   A0A3Q7TBH2   A0A3Q7Y473  

EC Number

2.3.1.48

Pubmed

19121390    26227816    26354079    20798317    24508170    30249741    + More
21282665    21719571    28648823    20566863    20075255    23142031    23537049    18362917    19820115    25474469    26334808    27129103    21292972    25401762    26823975    25765539    28503490    28049606    26830274    28797301    28327890    28528879    28812685    23127152    21881562    21993624    16341006    23915248    23594743    24845553    19892987    21709235    17975172   

EMBL

BABH01014967    EF554689    ABQ51913.1    DQ442997    ABD97987.1    ODYU01009919    + More
SOQ54659.1    GDQN01008671    GDQN01007897    JAT82383.1    JAT83157.1    JTDY01003329    KOB69725.1    KQ461137    KPJ08841.1    KQ459603    KPI93089.1    NEVH01012087    PNF30594.1    GL453161    EFN76370.1    KK107061    QOIP01000014    EZA61358.1    RLU14964.1    GBYB01006758    JAG76525.1    KQ982706    KYQ51869.1    GL764614    EFZ17437.1    KQ434896    KZC10768.1    KQ414786    KOC60897.1    KQ765605    OAD53831.1    GL435766    EFN72673.1    GEDC01022444    JAS14854.1    KQ977477    KYN02464.1    GEBQ01022589    JAT17388.1    KQ435699    KOX80586.1    GL888237    EGI64186.1    KQ976565    KYM80479.1    NNAY01001839    OXU22747.1    DS235271    EEB14154.1    KQ981215    KYN44579.1    KQ979074    KYN22725.1    KZ288375    PBC26692.1    KC110655    AFX63158.1    APGK01030338    KB740770    KB632132    ENN78994.1    ERL88997.1    KQ971321    EFA00694.1    GFTR01006109    JAW10317.1    GBBI01001996    JAC16716.1    GBGD01001567    JAC87322.1    GECL01002592    JAP03532.1    GDKW01002507    JAI54088.1    GL732538    EFX83058.1    GDIQ01132499    JAL19227.1    GDIQ01169673    JAK82052.1    GDIQ01241055    GDIQ01053977    JAK10670.1    GDIP01027310    JAM76405.1    GDIQ01123597    JAL28129.1    LRGB01002860    KZS05798.1    GDIP01143802    JAJ79600.1    GDIP01132345    JAL71369.1    GDIQ01022664    JAN72073.1    GDIP01237388    JAI86013.1    GDIP01235590    JAI87811.1    ACPB03009648    GDIP01155701    JAJ67701.1    GBHO01042555    GBRD01004830    GDHC01008455    JAG01049.1    JAG60991.1    JAQ10174.1    KK855294    PTY21862.1    JH431938    GDIQ01070519    JAN24218.1    GDIP01223576    JAI99825.1    GANP01006344    JAB78124.1    ABJB010100461    ABJB010504159    ABJB010565481    ABJB010677703    ABJB011090470    DS889418    EEC15527.1    GDIQ01088301    JAN06436.1    GFAC01002540    JAT96648.1    NCKU01006396    NCKU01005850    NCKU01005677    RWS03540.1    RWS04102.1    RWS04282.1    QCYY01001152    ROT80106.1    GDRN01075091    JAI63120.1    GGLE01002020    MBY06146.1    GEFH01001059    JAP67522.1    GFXV01001001    MBW12806.1    ABLF02011444    GGMR01017255    MBY29874.1    GEDV01008679    JAP79878.1    GFWV01002826    MAA27556.1    GDIP01136141    JAL67573.1    GFPF01008394    MAA19540.1    MNPL01014716    OQR71385.1    GFJQ02002286    JAW04684.1    NEDP02004422    OWF45646.1    GECZ01023952    JAS45817.1    CAEY01000863    JT408349    AHH38316.1    AAWZ02020217    AAEX03004380    GAEP01000973    JAB53848.1    AL928885    BX571714    KK853224    KDR09699.1    BC155277    BC171589    AAI55278.1    AAI71589.1    GABZ01001543    JAA51982.1    AEFK01076774    AEFK01076775    AANG04004202   

Proteomes

UP000005204    UP000037510    UP000053240    UP000053268    UP000235965    UP000008237    + More
UP000053097    UP000279307    UP000075809    UP000076502    UP000053825    UP000005203    UP000000311    UP000078542    UP000053105    UP000192223    UP000007755    UP000078540    UP000215335    UP000009046    UP000078541    UP000078492    UP000242457    UP000002358    UP000019118    UP000030742    UP000007266    UP000000305    UP000076858    UP000015103    UP000079169    UP000001555    UP000285301    UP000283509    UP000007819    UP000192247    UP000085678    UP000242188    UP000015104    UP000221080    UP000001646    UP000001811    UP000002254    UP000000437    UP000248481    UP000027135    UP000002281    UP000007648    UP000245340    UP000286641    UP000011712    UP000245341    UP000248482    UP000286640    UP000286642   

PRIDE

A5JPL6    A4K580   

Pfam

PF11717   Tudor-knot        + More
PF17772   zf-MYST
PF01853   MOZ_SAS

Interpro

IPR000953   Chromo/chromo_shadow_dom        + More
IPR040706   Zf-MYST       
IPR036388   WH-like_DNA-bd_sf       
IPR002717   HAT_MYST-type       
IPR016197   Chromo-like_dom_sf       
IPR016181   Acyl_CoA_acyltransferase       
IPR025995   Tudor-knot       
IPR037906   KAT8       

SUPFAM

SSF55729   SSF55729        + More
SSF54160   SSF54160       

Gene 3D

1.10.10.10    

CDD

cd00024  CHROMO

ProteinModelPortal

A5JPL6   A4K580   A0A2H1WNL7   A0A1E1W894   A0A0L7L2T3   A0A194QZ20   + More
A0A194PK37   A0A2J7QPU2   E2C6Q8   A0A026WZT6   A0A0C9PZ23   A0A151WVB7   E9IPR7   A0A154PHG8   A0A0L7QQJ7   A0A087ZR86   A0A310SAW0   E2A1K0   A0A1B6CN62   A0A151III6   A0A1B6L117   A0A0M9ABR3   A0A1W4XIV6   F4WNJ3   A0A195B8F6   A0A232EWM2   E0VL98   A0A195FXK8   A0A195EBX2   A0A2A3E5Y4   K7J356   K7WLT0   N6TF53   D6WHU4   A0A224XD32   A0A023F575   A0A069DUD7   A0A0V0G6Z5   A0A0N7Z8S8   E9GC17   A0A0N8BYH0   A0A0P5LH32   A0A0P5GH88   A0A0P6AM65   A0A0P5PVJ3   A0A164NB41   A0A0P5EG56   A0A0P5T1K5   A0A0P6IE21   A0A0P4XVK1   A0A0P4XZQ7   T1HIW2   A0A0P5DII3   A0A0A9VZK7   A0A3Q0ILL9   A0A2R7WQK2   T1J7N6   A0A0P6DZ38   A0A0P4YU28   V5HKI9   B7Q9K5   A0A0P6CXV2   A0A1E1XBR5   A0A3S3P3E0   A0A3R7PR76   A0A0N7ZC07   A0A2R5L9G8   A0A131XMD1   A0A2H8TFC8   X1WKV8   A0A2S2PKF7   A0A131YMS8   A0A293LHP2   A0A0P5SYK5   A0A224Z0K2   A0A1V9XCV5   A0A1Z5LCD9   A0A1S3J6A3   A0A210QA81   A0A1B6F6K3   T1L0F9   W5U8L4   H9GBU7   G1SH87   E2QT63   U3ES69   F1QX50   A0A2Y9I1F0   A0A067QV68   A9JTB7   K9ITZ6   F7B2S8   G3WE75   A0A2U3VQF6   A0A3Q7MRI4   M3VYT8   A0A2U3XEL0   A0A2Y9L7Y3   A0A3Q7TBH2   A0A3Q7Y473  

PDB

4DNC     E-value=3.57778e-130,     Score=1191

KEGG

100101212    K11308 histone acetyltransferase MYST1 [EC:2.3.1.48] | (RefSeq) MOF; MOF protein

GO

GO:0072487   GO:0006355   GO:0004402   GO:0045944   GO:0046972   GO:0000790   GO:0042393   GO:0045892   GO:0005634   GO:0000123   GO:0060215   GO:0071339   GO:0030099   GO:0010506   GO:0016363   GO:0043995   GO:0000776   GO:0043996   GO:0019899   GO:0035064   GO:0008134   GO:0045893   GO:0016747   GO:0008237   GO:0005245   GO:0005891   GO:0004674   GO:0006418   GO:0003723   GO:0046872   GO:0003824   GO:0016573  

PANTHER

PTHR10615:SF82  

Subcellular location

Nucleus  

Length:

442

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00723999999999999

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01137

outside

1  -  442

 

 

Pi

174.370782

Theta

189.703986

Tajima's D

-0.40319

CLR

0.21604

CSRT

0.267586620668967

Interpretation

Uncertain