Gene

KWMTBOMO10454

Pre Gene Modal

BGIBMGA007093

Annotation

PREDICTED:_solute_carrier_family_25_member_38-B-like_[Amyelois_transitella]

Location

Bomo_Chr17(+):11521022-11533893      View in EpiBrowser

Full name

Mitochondrial glycine transporter      

Alternative Name

Solute carrier family 25 member 38 homolog
Solute carrier family 25 member 38

Location in the cell

PlasmaMembrane   Reliability : 2.501

CDS

ATGGACATCGTGACTAACTATCATCCGGTGTTCAAAGCGTTTCTTGCGGGTTCGTTTTCTGGAACATTCAGCACTGTGCTCTTCCAGCCGTTGGATTTAGTGAAGACTCGTTTGCAGAATCCGAATCATCATGTCATGGCGGCTACAGTCAACGGCCGAATTCAACCCGGGATGATAACGATCTTCGCTAACATAATCCGTCAGGAGCAAATCGTTGGATTGTGGCGAGGGATGATACCCTCCGTTGCCCGATGTGTTCCCGGGGTCGGATTATATTTCTCTTCACTGCATTGGCTCAAAGGGAAGATGGGGAAGTCTACGGGAGACTTGAAAGCTATTGAGGCTGTTCTTTTGGGCGTTGTCGCAAGGACCATGAGCGGGATTGCCTTGATACCAATAACTGTGATAAAAACTAGGTACGAATCAGGGGTGTACAAATACACCAGTTTGAGTGGTGCTCTGAAATCCATATACAAAGCGGAAGGTCTTCGAGGTCTGTCCTGCGGCCTGGGTCCGACCTTGGCCCGGGACGCGCCGTTCTCGGGACTGTATCTAATGTTTTACACACAAACAAAACAAGCCGTTCCCAAAGAATGGCTTCAGTCACCAAGCGCTGCAAGTGCTATTCATTTCTCGTGCGGTATTGTCGCCGGGATCGCTGCCTCGCTGGCCACAAACCCGGCCGACGTTCTCAAGACGAAAATGCAACTTTATCCTGATAAGTTTCCAAACGCCTTTAGTGCCGCTGTTTACATCCATCAGACGTACGGAATTAAAGGGTATTTCAAAGGTGCCGTACCCAGGATGCTTCGTAGAACTCTCATGGCTGCAATGGCGTGGACTGTCTTCGAAGAAATAACAAGGTCTATTGGTTTAAAATGA

Protein

MDIVTNYHPVFKAFLAGSFSGTFSTVLFQPLDLVKTRLQNPNHHVMAATVNGRIQPGMITIFANIIRQEQIVGLWRGMIPSVARCVPGVGLYFSSLHWLKGKMGKSTGDLKAIEAVLLGVVARTMSGIALIPITVIKTRYESGVYKYTSLSGALKSIYKAEGLRGLSCGLGPTLARDAPFSGLYLMFYTQTKQAVPKEWLQSPSAASAIHFSCGIVAGIAASLATNPADVLKTKMQLYPDKFPNAFSAAVYIHQTYGIKGYFKGAVPRMLRRTLMAAMAWTVFEEITRSIGLK

Description

Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis.

Similarity

Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
Belongs to the mitochondrial carrier (TC 2.A.29) family.

Keywords

Complete proteome   Membrane   Mitochondrion   Mitochondrion inner membrane   Reference proteome   Repeat   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Mitochondrial glycine transporter

Uniprot

H9JC48   A0A2A4J1B5   A0A2H1VBG1   A0A2A4J1V6   A0A2A4J2J3   A0A212FDW6   + More
A0A194PI23   A0A194QTG5   A0A0L7LEL0   A0A2P8XD83   A0A067QJ41   D6WUT7   A0A1Y1LPJ9   A0A1Y1LJK9   J3JZC9   A0A2J7QWP8   V5GWM8   A0A0P4VIY3   R4G3U9   A0A069DS71   A0A224XTY8   A0A0V0G6C4   A0A1B6GWB2   E0VM89   A0A1B6FLE0   A0A3L8DIB2   K7IMY9   A0A232F042   A0A0C9R9Y0   A0A158NMF4   A0A1B6C0C5   E2BRU5   A0A1B6DWZ3   E2A2V1   E9IEG8   A0A0C9RR45   A0A2A3ENY5   A0A310SJZ2   A0A154P186   A0A026WEQ7   A0A151JU15   A0A088AC84   F4X5W1   A0A151J3U1   A0A151I3B9   A0A195CDX2   A0A226ECU2   A0A151JV59   A0A0P4VYX1   A0A146KQ10   A0A0K8SZW4   A0A151WSF5   A0A0A9XH04   A0A0L7RF76   A0A2L2Y0D6   A0A093BRF0   A0A091I516   A0A3M0JW78   A0A091IL77   A0A1D5P6J7   A0A091JPU7   G1NGU7   H0Z2B9   A0A3L8SZN9   A0A091FMX0   K7F8P4   A0A091MQ88   A0A093QT15   A0A093GNA3   A0A0A0A4N9   A0A091KEW0   A0A093NG99   A0A2R7WTT1   A0A0Q3MQZ6   A0A1V4J5C4   H3AA45   A0A087QH28   A0A1V4J5E3   A0A091V2F0   D5XMH0   A0A151P306   A0A091ERU7   A0A2I0TDM7   V3ZXS3   H3AA46   A0A151P2W0   A0A3Q0FS37   A0A091TE69   A0A1U8DYQ8   A0A093FHN8   A0A293N2A4   A0A2P2HWL4   A0A091VM05   Q6DJ08   M7BB87   A0A218UNN6   A0A093H819   A0A3Q0FVF6   A0A091U8X1   V9KVZ2  

Pubmed

19121390    22118469    26354079    26227816    29403074    24845553    + More
18362917    19820115    28004739    22516182    23537049    27129103    26334808    20566863    30249741    20075255    28648823    21347285    20798317    21282665    24508170    21719571    26823975    25401762    26561354    15592404    20838655    20360741    30282656    17381049    9215903    22293439    23254933    23624526    24402279   

EMBL

BABH01014896    BABH01014897    BABH01014898    BABH01014899    BABH01014900    NWSH01003936    + More
PCG65659.1    ODYU01001657    SOQ38183.1    PCG65658.1    PCG65660.1    AGBW02008995    OWR51939.1    KQ459603    KPI93066.1    KQ461137    KPJ08818.1    JTDY01001454    KOB73830.1    PYGN01002796    PSN29957.1    KK853286    KDR08945.1    KQ971363    EFA07797.1    GEZM01054080    JAV73855.1    GEZM01054081    JAV73854.1    APGK01041593    BT128610    KB740994    KB632255    AEE63567.1    ENN75981.1    ERL90658.1    NEVH01009422    PNF33009.1    GALX01002349    JAB66117.1    GDKW01002562    JAI54033.1    ACPB03005823    GAHY01001351    JAA76159.1    GBGD01002313    JAC86576.1    GFTR01004536    JAW11890.1    GECL01002497    JAP03627.1    GECZ01003116    JAS66653.1    DS235298    EEB14495.1    GECZ01018775    JAS50994.1    QOIP01000007    RLU20157.1    NNAY01001454    OXU23923.1    GBYB01009757    JAG79524.1    ADTU01020439    GEDC01030335    JAS06963.1    GL450042    EFN81578.1    GEDC01007118    JAS30180.1    GL436217    EFN72225.1    GL762591    EFZ21053.1    GBYB01009756    JAG79523.1    KZ288210    PBC32962.1    KQ760512    OAD60049.1    KQ434796    KZC05617.1    KK107238    EZA54585.1    KQ981847    KYN34996.1    GL888742    EGI58201.1    KQ980246    KYN17112.1    KQ976507    KYM82830.1    KQ977957    KYM98436.1    LNIX01000004    OXA55260.1    KQ981706    KYN37429.1    GDRN01086165    JAI61219.1    GDHC01020025    JAP98603.1    GBRD01007351    GDHC01019442    JAG58470.1    JAP99186.1    KQ982782    KYQ50721.1    GBHO01023602    GBRD01007352    GDHC01003541    JAG20002.1    JAG58469.1    JAQ15088.1    KQ414608    KOC69469.1    IAAA01009083    IAAA01009084    LAA01669.1    KN126788    KFU92661.1    KL536102    KFO94473.1    QRBI01000123    RMC05302.1    KL217907    KFP00391.1    AADN05000034    KK502279    KFP21953.1    ABQF01014145    ABQF01014146    ABQF01014147    QUSF01000003    RLW11680.1    KL447288    KFO71810.1    AGCU01076590    KK833110    KFP78046.1    KL423193    KFW89515.1    KL216618    KFV70753.1    KL870344    KGL87950.1    KK742205    KFP39119.1    KL224549    KFW61040.1    KK855521    PTY22948.1    LMAW01000947    KQK84904.1    LSYS01009165    OPJ67340.1    AFYH01234218    AFYH01234219    AFYH01234220    AFYH01234221    KL225582    KFM00532.1    OPJ67339.1    KL410402    KFQ96485.1    DP001180    DP001179    ADH10544.1    AKHW03001210    KYO43299.1    KK718893    KFO59327.1    KZ512127    PKU31885.1    KB203251    ESO85786.1    KYO43300.1    KK449399    KFQ72668.1    KK627286    KFV53826.1    GFWV01021600    MAA46328.1    IACF01000221    LAB66020.1    KK734086    KFR03755.1    BC075377    KB589327    EMP25492.1    MUZQ01000204    OWK55379.1    KK385524    KFV50843.1    KK420907    KFQ86512.1    JW870179    AFP02697.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000053240    UP000037510    + More
UP000245037    UP000027135    UP000007266    UP000019118    UP000030742    UP000235965    UP000015103    UP000009046    UP000279307    UP000002358    UP000215335    UP000005205    UP000008237    UP000000311    UP000242457    UP000076502    UP000053097    UP000078541    UP000005203    UP000007755    UP000078492    UP000078540    UP000078542    UP000198287    UP000075809    UP000053825    UP000269221    UP000054308    UP000000539    UP000053119    UP000001645    UP000007754    UP000276834    UP000053760    UP000007267    UP000053875    UP000053858    UP000054081    UP000051836    UP000190648    UP000008672    UP000053286    UP000053283    UP000050525    UP000052976    UP000030746    UP000189705    UP000053605    UP000008143    UP000031443    UP000197619   

PRIDE

H9JC48   

Pfam

PF00153   Mito_carr

Interpro

IPR023395   Mt_carrier_dom_sf        + More
IPR018108   Mitochondrial_sb/sol_carrier       
IPR030847   Hem25/SLC25A38       
IPR002067   Mit_carrier       

SUPFAM

SSF103506   SSF103506       

Gene 3D

1.50.40.10    

ProteinModelPortal

H9JC48   A0A2A4J1B5   A0A2H1VBG1   A0A2A4J1V6   A0A2A4J2J3   A0A212FDW6   + More
A0A194PI23   A0A194QTG5   A0A0L7LEL0   A0A2P8XD83   A0A067QJ41   D6WUT7   A0A1Y1LPJ9   A0A1Y1LJK9   J3JZC9   A0A2J7QWP8   V5GWM8   A0A0P4VIY3   R4G3U9   A0A069DS71   A0A224XTY8   A0A0V0G6C4   A0A1B6GWB2   E0VM89   A0A1B6FLE0   A0A3L8DIB2   K7IMY9   A0A232F042   A0A0C9R9Y0   A0A158NMF4   A0A1B6C0C5   E2BRU5   A0A1B6DWZ3   E2A2V1   E9IEG8   A0A0C9RR45   A0A2A3ENY5   A0A310SJZ2   A0A154P186   A0A026WEQ7   A0A151JU15   A0A088AC84   F4X5W1   A0A151J3U1   A0A151I3B9   A0A195CDX2   A0A226ECU2   A0A151JV59   A0A0P4VYX1   A0A146KQ10   A0A0K8SZW4   A0A151WSF5   A0A0A9XH04   A0A0L7RF76   A0A2L2Y0D6   A0A093BRF0   A0A091I516   A0A3M0JW78   A0A091IL77   A0A1D5P6J7   A0A091JPU7   G1NGU7   H0Z2B9   A0A3L8SZN9   A0A091FMX0   K7F8P4   A0A091MQ88   A0A093QT15   A0A093GNA3   A0A0A0A4N9   A0A091KEW0   A0A093NG99   A0A2R7WTT1   A0A0Q3MQZ6   A0A1V4J5C4   H3AA45   A0A087QH28   A0A1V4J5E3   A0A091V2F0   D5XMH0   A0A151P306   A0A091ERU7   A0A2I0TDM7   V3ZXS3   H3AA46   A0A151P2W0   A0A3Q0FS37   A0A091TE69   A0A1U8DYQ8   A0A093FHN8   A0A293N2A4   A0A2P2HWL4   A0A091VM05   Q6DJ08   M7BB87   A0A218UNN6   A0A093H819   A0A3Q0FVF6   A0A091U8X1   V9KVZ2  

PDB

2LCK     E-value=7.99432e-13,     Score=177

KEGG

101745781    K15118 solute carrier family 25, member 38 | (RefSeq) solute carrier family 25 member 38-B-like

GO

GO:0015187   GO:0005743   GO:1904983   GO:0016021   GO:0022857   GO:0005739   GO:0030218   GO:0005215   GO:0006810   GO:0005245   GO:0005891   GO:0004674   GO:0006418   GO:0003723   GO:0046872   GO:0003824   GO:0055085  

Subcellular location

Mitochondrion inner membrane  

Length:

293

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

71.1434000000001

Exp number, first 60 AAs:

22.75112

Total prob of N-in:

0.74022

POSSIBLE N-term signal

sequence

outside

1  -  293

 

 

Pi

236.19389

Theta

175.006603

Tajima's D

0.810582

CLR

0.235881

CSRT

0.609869506524674

Interpretation

Uncertain