Gene

KWMTBOMO10453  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007092

Annotation

transgelin_[Bombyx_mori]

Location

Bomo_Chr17(+):11490452-11509043      View in EpiBrowser

Full name

Transgelin       + More
Calponin      

Location in the cell

Cytoplasmic   Reliability : 1.383 Nuclear   Reliability : 1.839

CDS

ATGGCAAACAACCGAGCGACCAAATCAGGATTTGCAGCTGAAGCCCAGAGAAAGATCAACAGCAAATACAGCGAGGAGCTGGCCCACGAGTCCTTGGAATGGATTCGGATGATCACCGGCGAACCAGAGAACACCTCAGGGGATATGGACAACTTCTACGAAGTGCTTAAAGACGGCACTCTTCTGTGCAAGCTAGCCAACAACATCCACCCGAACATGATCAAAAAGATCAACACATCGTCGATGGCCTTCAAGTGCATGGAGAATATCAACGCTTTCCTCGAAGCCGCAAGACAGTTGGGTGTACCGGCACAGGAAACTTTTCAAACTGTCGACCTGTGGGAGAGACAGAATCTCAACTCCGTCGTGATCTGCTTGCAGTCACTGGGCAGAAAGGCTGGAACCTACGGGAAGCCGTCAATAGGACCGAAAGAAGCTGAGAAGAACGTGCGAAACTTCTCCGAGGAGCAGCTCCGGGCTGGTCAGGGAGTCATATCTCTTCAGTACGGTTCAAATAAGGGCGCCAACCAAAGCGGAATCAACTTTGGTAACACGAGACACATGTAA

Protein

MANNRATKSGFAAEAQRKINSKYSEELAHESLEWIRMITGEPENTSGDMDNFYEVLKDGTLLCKLANNIHPNMIKKINTSSMAFKCMENINAFLEAARQLGVPAQETFQTVDLWERQNLNSVVICLQSLGRKAGTYGKPSIGPKEAEKNVRNFSEEQLRAGQGVISLQYGSNKGANQSGINFGNTRHM

Description

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

Similarity

Belongs to the calponin family.

Feature

chain  Transgelin

Uniprot

Q1HQ70   A0A1E1WN47   A0A3S2TPH9   H9JC47   A0A194QTM3   I4DNE6   + More
A0A2A4J0G7   A0A2H1VJF7   A0A212FDZ4   S4PMM4   A0A2A3EBY9   V9IDZ7   A0A088AJ47   R4WR80   R4UW18   V5GZ80   A0A1B6FMU2   A0A1B6IPQ6   K7ISL6   A0A195EZC6   A0A1B6L9J9   A0A0C9QLT0   A0A3L8DZH0   A0A1W4W8P8   A0A0A9WIH3   A0A023F9W3   A0A158NDR9   A0A170ZFV1   A0A0K8TZF1   A0A034WQN6   D6WHC6   A0A1B0GIN7   W8BCE9   A0A069DPP4   A0A1B6CS28   D3TSC5   R4FN05   B4L9E1   J3JYP4   T1DIU2   A0A1L8E5Z6   A0A0A1XN87   B4N3J5   A0A1I8NH87   B4LB83   U5EYQ9   B3M4V0   A0A182RNK3   A0A1I8P873   A0A182Q8Q7   A0A0L0BR69   A0A182VVS7   A0A182X9L4   A0A182VDH7   A0A182HKJ7   Q7PXA9   T1DN20   A0A2M3Z084   A0A2M4A8L1   A0A087ZJX0   A0A1I8P874   A0A1L8EIE7   A0A224XXM0   A0A182NQJ8   Q1HR19   A0A023EJ28   A0A1W4W6W8   Q29D85   B4H7U8   A0A1Q3EUJ0   A0A3B0J6R8   A0A0J9RP62   B4PHP6   B4HU00   B3NG36   Q9VZI1   B4J1D9   A0A0M3QWF1   A0A2H8TX02   J9JTC0   A0A0K8TPC4   A0A336KB30   A0A2S2QST3   B5M0M6   E9H6I9   E0VJY3   A0A0P5PQL4   A0A164L2F8   A0A0P5JIE3   A0A0P5J190   A0A0P5JMN8   A0A0P5DHA7   A0A0P5UJ25   A0A1B6H4F3   A0A0N8EAJ2   A0A0L7R7U5   A0A0P5ZI04   A0A1Y1MTF4   A0A151X435   A0A067QIW9  

Pubmed

19121390    26354079    22651552    22118469    23622113    23691247    + More
20075255    30249741    25401762    26823975    25474469    21347285    25348373    18362917    19820115    24495485    26334808    20353571    17994087    22516182    23537049    24330624    25830018    25315136    26108605    12364791    14747013    17210077    20920257    17204158    17510324    24945155    15632085    22936249    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    26369729    19166301    21292972    20566863    28004739    24845553   

EMBL

DQ443182    ABF51271.1    GDQN01002778    JAT88276.1    RSAL01000031    RVE51633.1    + More
BABH01014894    KQ461137    KPJ08817.1    AK402870    KQ459603    BAM19436.1    KPI93065.1    NWSH01003936    PCG65657.1    ODYU01002898    SOQ40965.1    AGBW02008995    OWR51940.1    GAIX01000101    JAA92459.1    KZ288290    PBC29238.1    JR041079    AEY59353.1    AK417172    BAN20387.1    KC571917    AGM32416.1    GALX01001249    JAB67217.1    GECZ01018242    JAS51527.1    GECU01018823    JAS88883.1    KQ981906    KYN33262.1    GEBQ01019588    JAT20389.1    GBYB01004509    GBYB01011628    JAG74276.1    JAG81395.1    QOIP01000002    RLU25329.1    GBHO01036398    GBRD01016895    GDHC01000434    JAG07206.1    JAG48932.1    JAQ18195.1    GBBI01000923    JAC17789.1    ADTU01012849    ADTU01012850    ADTU01012851    GEMB01002249    JAS00931.1    GDHF01032661    JAI19653.1    GAKP01002447    JAC56505.1    KQ971321    EFA00109.1    AJWK01015120    AJWK01015121    AJWK01015122    GAMC01010188    JAB96367.1    GBGD01003099    JAC85790.1    GEDC01021255    JAS16043.1    EZ424327    ADD20603.1    GAHY01000753    JAA76757.1    CH933816    EDW17316.1    APGK01042702    APGK01042703    BT128374    KB741007    KB631811    AEE63332.1    ENN75624.1    ERL86344.1    GALA01000756    JAA94096.1    GFDF01000152    JAV13932.1    GBXI01002244    JAD12048.1    CH964095    EDW79200.1    CH940647    EDW68647.1    GANO01001867    JAB58004.1    CH902618    EDV40524.1    AXCN02001518    JRES01001494    KNC22483.1    APCN01000834    AAAB01008987    EAA01312.4    GAMD01003245    JAA98345.1    GGFM01001184    MBW21935.1    GGFK01003815    MBW37136.1    GGFL01004380    MBW68558.1    GFDG01000374    JAV18425.1    GFTR01003134    JAW13292.1    DQ440275    CH477412    ABF18308.1    EAT41438.1    GAPW01004775    GAPW01004774    JAC08824.1    CH379070    EAL30529.2    CH479219    EDW34738.1    GFDL01016119    JAV18926.1    OUUW01000002    SPP77425.1    CM002912    KMY97497.1    CM000159    EDW93355.1    CH480817    EDW50421.1    CH954178    EDV50865.1    AF217286    AE014296    AY060355    AAF44064.1    AAF47840.2    AAL25394.1    CH916366    EDV95830.1    CP012525    ALC44039.1    GFXV01006635    MBW18440.1    ABLF02039726    GDAI01001366    JAI16237.1    UFQS01000192    UFQT01000192    SSX01032.1    SSX21412.1    GGMS01011626    MBY80829.1    EU930212    ACH56840.1    GL732597    EFX72670.1    DS235235    EEB13689.1    GDIQ01198920    GDIQ01125194    GDIP01045273    JAL26532.1    JAM58442.1    LRGB01003216    KZS03737.1    GDIQ01250565    GDIQ01224117    JAK27608.1    GDIQ01206474    JAK45251.1    GDIQ01197572    JAK54153.1    GDIP01156335    JAJ67067.1    GDIP01112305    JAL91409.1    GECZ01000226    JAS69543.1    GDIQ01045732    JAN49005.1    KQ414637    KOC66950.1    GDIP01043672    JAM60043.1    GEZM01021540    JAV88952.1    KQ982548    KYQ55195.1    KK853293    KDR08819.1   

Proteomes

UP000283053    UP000005204    UP000053240    UP000053268    UP000218220    UP000007151    + More
UP000242457    UP000005203    UP000002358    UP000078541    UP000279307    UP000192223    UP000005205    UP000007266    UP000092461    UP000009192    UP000019118    UP000030742    UP000007798    UP000095301    UP000008792    UP000007801    UP000075900    UP000095300    UP000075886    UP000037069    UP000075920    UP000076407    UP000075903    UP000075840    UP000007062    UP000075884    UP000008820    UP000192221    UP000001819    UP000008744    UP000268350    UP000002282    UP000001292    UP000008711    UP000000803    UP000001070    UP000092553    UP000007819    UP000000305    UP000009046    UP000076858    UP000053825    UP000075809    UP000027135   

PRIDE

Q1HQ70    H9JC47    Q9VZI1   

Pfam

PF00307   CH        + More
PF00402   Calponin

Interpro

IPR000557   Calponin_repeat        + More
IPR003096   SM22_calponin       
IPR036872   CH_dom_sf       
IPR001715   CH-domain       
IPR001997   Calponin/LIMCH1       

SUPFAM

SSF47576   SSF47576       

Gene 3D

1.10.418.10    

CDD

cd00014  CH

ProteinModelPortal

Q1HQ70   A0A1E1WN47   A0A3S2TPH9   H9JC47   A0A194QTM3   I4DNE6   + More
A0A2A4J0G7   A0A2H1VJF7   A0A212FDZ4   S4PMM4   A0A2A3EBY9   V9IDZ7   A0A088AJ47   R4WR80   R4UW18   V5GZ80   A0A1B6FMU2   A0A1B6IPQ6   K7ISL6   A0A195EZC6   A0A1B6L9J9   A0A0C9QLT0   A0A3L8DZH0   A0A1W4W8P8   A0A0A9WIH3   A0A023F9W3   A0A158NDR9   A0A170ZFV1   A0A0K8TZF1   A0A034WQN6   D6WHC6   A0A1B0GIN7   W8BCE9   A0A069DPP4   A0A1B6CS28   D3TSC5   R4FN05   B4L9E1   J3JYP4   T1DIU2   A0A1L8E5Z6   A0A0A1XN87   B4N3J5   A0A1I8NH87   B4LB83   U5EYQ9   B3M4V0   A0A182RNK3   A0A1I8P873   A0A182Q8Q7   A0A0L0BR69   A0A182VVS7   A0A182X9L4   A0A182VDH7   A0A182HKJ7   Q7PXA9   T1DN20   A0A2M3Z084   A0A2M4A8L1   A0A087ZJX0   A0A1I8P874   A0A1L8EIE7   A0A224XXM0   A0A182NQJ8   Q1HR19   A0A023EJ28   A0A1W4W6W8   Q29D85   B4H7U8   A0A1Q3EUJ0   A0A3B0J6R8   A0A0J9RP62   B4PHP6   B4HU00   B3NG36   Q9VZI1   B4J1D9   A0A0M3QWF1   A0A2H8TX02   J9JTC0   A0A0K8TPC4   A0A336KB30   A0A2S2QST3   B5M0M6   E9H6I9   E0VJY3   A0A0P5PQL4   A0A164L2F8   A0A0P5JIE3   A0A0P5J190   A0A0P5JMN8   A0A0P5DHA7   A0A0P5UJ25   A0A1B6H4F3   A0A0N8EAJ2   A0A0L7R7U5   A0A0P5ZI04   A0A1Y1MTF4   A0A151X435   A0A067QIW9  

PDB

1WYM     E-value=1.22815e-17,     Score=216

KEGG

732906    K20526 transgelin | (RefSeq) transgelin

GO

GO:0031032   GO:0003779   GO:0005516   GO:0035626   GO:0070594   GO:0005865   GO:0006939   GO:0005515   GO:0008417   GO:0016020   GO:0005245   GO:0005891   GO:0004674   GO:0006418   GO:0003723   GO:0046872   GO:0003824  

Length:

188

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00064

Exp number, first 60 AAs:

5e-05

Total prob of N-in:

0.44779

outside

1  -  188

 

 

Pi

197.758223

Theta

170.93547

Tajima's D

0.610846

CLR

0.014182

CSRT

0.544372781360932

Interpretation

Uncertain