Gene

KWMTBOMO10424  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007082

Annotation

U2_small_nuclear_ribonucleoprotein_auxiliary_factor_2_[Bombyx_mori]

Location

Bomo_Chr17(+):10702094-10706813      View in EpiBrowser

Full name

U2 snRNP auxiliary factor large subunit      

Location in the cell

Nuclear   Reliability : 3.342

CDS

ATGGGGGAAGATAAAGACCGCCGACGAAGGTCTCGATCCCGAGAAAGAAAACGTTCTAGATCTCGATCTAGAGAACGAAGAGAAAAAAGAAAAAGCAGATCAAGATCGCCCAATAAACGTTCACGTAGACGTAAGCCTTCGCTTTACTGGGATGTACCGCCGCCGGGATTCGAGCATATCACGCCATTACAATACAAGGCGATGCAAGCGGCGGGTCAGATTCCTGCCAATATTGTCGCCGACACACCACAAGCTGCCGTGCCGGTGGTGGGTTCGACTATAACACGTCAAGCGCGAAGGTTATATGTCGGCAACATACCCTTTGGCGTCACCGAAGAAGAAACAATGGAGTTTTTCAATCAACAAATGCATCTATCGGGCCTGGCCCAGGCCGCCGGCAACCCTGTTTTGGCTTGCCAGATTAATTTAGATAAAAATTTTGCATTCCTTGAATTCAGATCAATTGATGAAACGACACAGGCAATGGCTTTTGACGGTATTAATTTTAAAGGGCAAAGCTTAAAGATTCGACGTCCACATGACTACCAGCCTATGCCAGGCACTGAAAACCCAGCAATAAATGTGCCTGCTGGTGTTATTAGCACTGTTGTACCTGATTCCCCACACAAGATCTTTATAGGGGGATTGCCTAATTATCTAAATGAGGACCAAGTAAAGGAATTACTCATGTCATTTGGTCAACTCCGGGCCTTCAATTTGGTGAAAGACTCTTCAACTGGGTTGAGCAAAGGCTATGCTTTTGCTGAATATGTCGACATTTCTATGACAGATCAGGCTATTGCAGGTTTAAATGGAATGCAACTTGGAGATAAAAAGTTGATTGTGCAACGTGCCAGTATAGGCGCAAAGAATTCAACTTTAGCACTGACCGGTGCAGCTCCAGTGCAAATCCAAGTGGCAGGTTTGACCTTGGCTGGAGCAGGTCCACCTACTGAAGTATTGTGCCTTCTTAACATGGTAACACCTGATGAATTGCGTGATGAAGAGGAGTATGAAGATATCCTTGAAGATATAAAGGAGGAATGCAACAAATATGGTGTTGTGCGTAGTATAGAAATTCCAAGACCAATTGAAGGAGTCGAAGTACCTGGATGCGGCAAGGTATTTGTCGAGTTCAACAGTATTGCAGATTGCCAGAAAGCGCAGCAGACGCTCACAGGACGCAAGTTCAGTAACAGAGTCGTCGTCACATCCTACTTCGATCCTGACAAATATCATCGCAGAGAGTTTTAA

Protein

MGEDKDRRRRSRSRERKRSRSRSRERREKRKSRSRSPNKRSRRRKPSLYWDVPPPGFEHITPLQYKAMQAAGQIPANIVADTPQAAVPVVGSTITRQARRLYVGNIPFGVTEEETMEFFNQQMHLSGLAQAAGNPVLACQINLDKNFAFLEFRSIDETTQAMAFDGINFKGQSLKIRRPHDYQPMPGTENPAINVPAGVISTVVPDSPHKIFIGGLPNYLNEDQVKELLMSFGQLRAFNLVKDSSTGLSKGYAFAEYVDISMTDQAIAGLNGMQLGDKKLIVQRASIGAKNSTLALTGAAPVQIQVAGLTLAGAGPPTEVLCLLNMVTPDELRDEEEYEDILEDIKEECNKYGVVRSIEIPRPIEGVEVPGCGKVFVEFNSIADCQKAQQTLTGRKFSNRVVVTSYFDPDKYHRREF

Description

Necessary for the splicing of pre-mRNA.

Similarity

Belongs to the splicing factor SR family.
Belongs to the actin family.

Uniprot

Q1HPI9   A0A2H1V9C0   A0A212FB56   A0A194QTD6   I4DMA8   A0A194PI95   + More
A0A067QMY3   A0A2J7PXI8   D6WWI5   N6T0Q2   A0A1W4WGF7   A0A1W4WGF2   A0A1Y1MYJ3   A0A2J7PXG7   A0A0K8TNC0   A0A182VHX9   A0A182MDT9   U5EYF5   A0A1B0CGA9   A0A182XHI0   Q7QD20   A0A1L8DGX9   A0A182QZP3   A0A182JYS5   A0A182HTW6   A0A182N4U9   A0A182XV36   A0A182VRN9   A0A336LJ98   E0VVA1   A0A182J365   A0A1B6E2F3   A0A084VTB9   E2AL95   A0A026WKD1   R4WDY3   A0A2M4CQ74   A0A1B6GK80   A0A0J7L4I2   A0A0M8ZS79   A0A158NFG6   A0A1J1ICX4   A0A2A3E3I3   A0A232ERJ9   A0A146KW41   A0A0A9YNN4   A0A182R4R8   A0A1B6E1E4   A0A182H3K3   Q17H60   K7IS62   A0A182P643   A0A182U4I0   T1E1I1   A0A151JVJ8   E2C4G0   R4FQC3   A0A224XPW4   A0A069DUD3   A0A1Q3F0R9   A0A1Q3F0J5   A0A1Q3F0U1   A0A1Q3F0P2   A0A1Q3F0E8   A0A1Q3F0K8   A0A1Q3F0Z2   A0A0A9YYL5   A0A0A1X1B1   A0A034VE65   A0A0N7Z9K4   A0A182H9Y1   A0A2M4CUC6   A0A182F7D1   B0X0B4   A0A0K8V4B2   A0A2M3Z469   A0A2M4AFC6   A0A2M4AF51   F4WGU1   A0A154PQV4   A0A1B0A3C7   A0A0R3P689   A0A1A9W316   A0A3B0K5X1   Q29GJ0   B4H105   A0A1A9YDI4   A0A1B0BX66   B4NCL6   A0A1B0A3C8   A0A1A9W317   D3TNR8   A0A1A9YDI7   A0A1B0BX61   B3N0S6   A0A0P9AAI2   A0A1B0FK90   M9NF89   A0A0P8XKH7   A0A1W4WDT1  

Pubmed

19121390    22118469    26354079    22651552    24845553    18362917    + More
19820115    23537049    28004739    26369729    12364791    14747013    17210077    25244985    20566863    24438588    20798317    24508170    23691247    21347285    28648823    26823975    25401762    26483478    17510324    20075255    24330624    26334808    25830018    25348373    27129103    21719571    15632085    17994087    20353571    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867   

EMBL

BABH01014830    DQ443413    ABF51502.1    ODYU01001340    SOQ37386.1    AGBW02009379    + More
OWR50957.1    KQ461137    KPJ08788.1    AK402426    BAM19048.1    KQ459603    KPI93037.1    KK853134    KDR10843.1    NEVH01020858    PNF21034.1    KQ971361    EFA08132.1    APGK01056522    KB741277    KB632408    ENN71063.1    ERL95151.1    GEZM01017365    JAV90751.1    PNF21035.1    GDAI01001980    JAI15623.1    AXCM01002602    GANO01000392    JAB59479.1    AJWK01010945    AAAB01008859    EAA08228.4    GFDF01008413    JAV05671.1    AXCN02000010    APCN01000586    UFQS01000021    UFQT01000021    SSW97554.1    SSX17940.1    DS235805    EEB17307.1    GEDC01005221    JAS32077.1    ATLV01016291    ATLV01016292    KE525074    KFB41213.1    GL440553    EFN65791.1    KK107167    EZA56490.1    AK418048    BAN21263.1    GGFL01003314    MBW67492.1    GECZ01006941    JAS62828.1    LBMM01000671    KMQ97822.1    KQ435912    KOX68896.1    ADTU01014478    ADTU01014479    CVRI01000047    CRK97602.1    KZ288400    PBC26287.1    NNAY01002580    OXU21003.1    GDHC01018161    JAQ00468.1    GBHO01015256    GBHO01008967    GDHC01002629    JAG28348.1    JAG34637.1    JAQ16000.1    GEDC01005552    JAS31746.1    JXUM01107531    JXUM01107532    KQ565150    KXJ71280.1    CH477253    EAT45953.1    GALA01001644    JAA93208.1    KQ981724    KYN37241.1    GL452471    EFN77144.1    ACPB03022631    GAHY01000479    JAA77031.1    GFTR01006233    JAW10193.1    GBGD01001503    JAC87386.1    GFDL01013890    JAV21155.1    GFDL01013969    JAV21076.1    GFDL01013870    JAV21175.1    GFDL01013923    JAV21122.1    GFDL01014015    JAV21030.1    GFDL01013955    JAV21090.1    GFDL01013824    JAV21221.1    GBHO01008970    GBHO01008969    JAG34634.1    JAG34635.1    GBXI01009869    JAD04423.1    GAKP01017351    GAKP01017345    JAC41601.1    GDKW01000299    JAI56296.1    JXUM01121634    KQ566520    KXJ70060.1    GGFL01004742    MBW68920.1    DS232232    EDS38076.1    GDHF01018603    JAI33711.1    GGFM01002558    MBW23309.1    GGFK01006101    MBW39422.1    GGFK01006100    MBW39421.1    GL888147    EGI66560.1    KQ435056    KZC14289.1    CH379064    KRT06931.1    OUUW01000021    SPP89525.1    EAL32119.2    CH479201    EDW29921.1    JXJN01022088    CH964239    EDW82575.1    CCAG010000333    EZ423070    ADD19346.1    CH902644    EDV34805.1    KPU75294.1    AE014298    AFH07421.1    KPU75293.1   

Proteomes

UP000005204    UP000007151    UP000053240    UP000053268    UP000027135    UP000235965    + More
UP000007266    UP000019118    UP000030742    UP000192223    UP000075903    UP000075883    UP000092461    UP000076407    UP000007062    UP000075886    UP000075881    UP000075840    UP000075884    UP000076408    UP000075920    UP000009046    UP000075880    UP000030765    UP000000311    UP000053097    UP000036403    UP000053105    UP000005205    UP000183832    UP000242457    UP000215335    UP000075900    UP000069940    UP000249989    UP000008820    UP000002358    UP000075885    UP000075902    UP000078541    UP000008237    UP000015103    UP000069272    UP000002320    UP000007755    UP000076502    UP000092445    UP000001819    UP000091820    UP000268350    UP000008744    UP000092443    UP000092460    UP000007798    UP000092444    UP000007801    UP000000803    UP000192221   

PRIDE

Q1HPI9    M9NF89   

Pfam

PF00076   RRM_1        + More
PF03770   IPK
PF00022   Actin
PF02902   Peptidase_C48

Interpro

IPR012677   Nucleotide-bd_a/b_plait_sf        + More
IPR000504   RRM_dom       
IPR006529   U2AF_lg       
IPR035979   RBD_domain_sf       
IPR003954   RRM_dom_euk       
IPR038286   IPK_sf       
IPR005522   IPK       
IPR013087   Znf_C2H2_type       
IPR004000   Actin       
IPR038765   Papain-like_cys_pep_sf       
IPR003653   Peptidase_C48_C       

SUPFAM

SSF54928   SSF54928        + More
SSF54001   SSF54001       

Gene 3D

3.30.70.330     1.10.510.50    

ProteinModelPortal

Q1HPI9   A0A2H1V9C0   A0A212FB56   A0A194QTD6   I4DMA8   A0A194PI95   + More
A0A067QMY3   A0A2J7PXI8   D6WWI5   N6T0Q2   A0A1W4WGF7   A0A1W4WGF2   A0A1Y1MYJ3   A0A2J7PXG7   A0A0K8TNC0   A0A182VHX9   A0A182MDT9   U5EYF5   A0A1B0CGA9   A0A182XHI0   Q7QD20   A0A1L8DGX9   A0A182QZP3   A0A182JYS5   A0A182HTW6   A0A182N4U9   A0A182XV36   A0A182VRN9   A0A336LJ98   E0VVA1   A0A182J365   A0A1B6E2F3   A0A084VTB9   E2AL95   A0A026WKD1   R4WDY3   A0A2M4CQ74   A0A1B6GK80   A0A0J7L4I2   A0A0M8ZS79   A0A158NFG6   A0A1J1ICX4   A0A2A3E3I3   A0A232ERJ9   A0A146KW41   A0A0A9YNN4   A0A182R4R8   A0A1B6E1E4   A0A182H3K3   Q17H60   K7IS62   A0A182P643   A0A182U4I0   T1E1I1   A0A151JVJ8   E2C4G0   R4FQC3   A0A224XPW4   A0A069DUD3   A0A1Q3F0R9   A0A1Q3F0J5   A0A1Q3F0U1   A0A1Q3F0P2   A0A1Q3F0E8   A0A1Q3F0K8   A0A1Q3F0Z2   A0A0A9YYL5   A0A0A1X1B1   A0A034VE65   A0A0N7Z9K4   A0A182H9Y1   A0A2M4CUC6   A0A182F7D1   B0X0B4   A0A0K8V4B2   A0A2M3Z469   A0A2M4AFC6   A0A2M4AF51   F4WGU1   A0A154PQV4   A0A1B0A3C7   A0A0R3P689   A0A1A9W316   A0A3B0K5X1   Q29GJ0   B4H105   A0A1A9YDI4   A0A1B0BX66   B4NCL6   A0A1B0A3C8   A0A1A9W317   D3TNR8   A0A1A9YDI7   A0A1B0BX61   B3N0S6   A0A0P9AAI2   A0A1B0FK90   M9NF89   A0A0P8XKH7   A0A1W4WDT1  

PDB

5EV4     E-value=9.10182e-92,     Score=860

KEGG

733037    K12837 splicing factor U2AF 65 kDa subunit | (RefSeq) U2 small nuclear ribonucleoprotein auxiliary f

PATHWAY

03040    Spliceosome - Bombyx mori (domestic silkworm)

GO

GO:0005634   GO:0008380   GO:0006397   GO:0003723   GO:0000243   GO:0016607   GO:0008187   GO:0089701   GO:0030628   GO:0071004   GO:0016301   GO:0032958   GO:0008234   GO:0000166   GO:0003676   GO:0003917   GO:0006418   GO:0046872   GO:0003824  

Subcellular location

Nucleus  

Length:

417

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.17597

Exp number, first 60 AAs:

0.0014

Total prob of N-in:

0.09434

outside

1  -  417

 

 

Pi

199.733077

Theta

196.389706

Tajima's D

0.110927

CLR

0.133791

CSRT

0.399730013499325

Interpretation

Uncertain