Gene

KWMTBOMO10423

Pre Gene Modal

BGIBMGA007020

Annotation

PREDICTED:_major_facilitator_superfamily_domain-containing_protein_10-like_[Bombyx_mori]

Location

Bomo_Chr17(-):10683083-10693423      View in EpiBrowser

Full name

SAGA-associated factor 11 homolog      

Location in the cell

PlasmaMembrane   Reliability : 4.976

CDS

ATGATTCTTCCACTGTTGCCGTCTTTAATGGATTATTACAGCAGAGAGGAAAATCAGGAGAATAGTCTATACTCTACATTGTTACAGGCAGTTCGGAGTTTTCAAAAATTAACCGGGGCACCAGATCGATTCGTGTCTGTCTTGTTTGGGGGTGCGCTGGGCTCCATGTATAGTTTTCTTCAGTTCCTAACGAGTCCTATTGTAGGTAGCCTCTCGGACGCATATGGAAGAAAACCAATGCTACTGATATGCCTGACAGGTATAGCGGCATCACATGCACTGTGGAGTTTGGCTGAAACATTCCTTATATTTGTAGTAGCTCGATTCATTGGTGGATTAAGCAAAGCCAATGTAAGTCTGTGCATGGCCATAGTAACCGATGCTTCAACTGAAAAAACTAGAGCAAGAGGAATGGCCCTGGTGGGTTTGGCGTTTTCCGTAGCATTCATAGTGGGGCCGCTATGTGGTGCGTGGTTTGCTAAAACGAGCGATATTACCAACGGGCCGTGGGGCGAGCGACCGGCATTATACGCGTTGTTCCTCTCGATAGCTAACATAGCTCTGGTGGCATTTTGTTTACCCGAAACCTTAGCAAAGGAGAAAAGAGCCCCCGTATCGTTTACATTATATAAAACTGTGGATTTCGTTTCTCCATGGCATTTACTTAACTTTACAGCTGTAGAAAATTTATCTCACTATCAAAAAAAAGTATTATCGAAATTGGGATTAATTTATTTTCTATATTTGTTTGTATATTCTGGACTCGAATTCACTATAACATTCCTGACGCATCACAATTTTAAGTATACAGCAATGCAACAAGGAAAAATGTTTTTGGTAATAGGTTTAATAATGGCTGTACTGCAAGGCGGTGCGGCGAGGAGGCTCGGCACTAAAAGCGCGGAAGTGGCAGCGCGAGTGTCAGTGGCTCTAACTCCGTTCGCGTTCCTGTGTATAGCGTTAGCCGCTCTATCGAATCCGCCATTTTTGGCCCCGTTGATATGGCTATGGACCGGCTTAGTCTTGTACGCTTTATCTACGGCGTTCGCGGTGTCTTGCATGACGTCAATAGGAGCCAACCGAGCACCGGGTGCGGCCCGCGGCGCCGTCCTCGGCACTCTGCGCTCGCTGGGAGCGCTAGCCAGGGCTGCCGGCCCACTTCTTACATCTTCAGTTTATTGGTATTCTGGAGCAGCCATCACATATGCTATTGGTTCTTTAATTCTTATCATTCCAACTGTGATGTTATTTAGACTGAAAACTTGA

Protein

MILPLLPSLMDYYSREENQENSLYSTLLQAVRSFQKLTGAPDRFVSVLFGGALGSMYSFLQFLTSPIVGSLSDAYGRKPMLLICLTGIAASHALWSLAETFLIFVVARFIGGLSKANVSLCMAIVTDASTEKTRARGMALVGLAFSVAFIVGPLCGAWFAKTSDITNGPWGERPALYALFLSIANIALVAFCLPETLAKEKRAPVSFTLYKTVDFVSPWHLLNFTAVENLSHYQKKVLSKLGLIYFLYLFVYSGLEFTITFLTHHNFKYTAMQQGKMFLVIGLIMAVLQGGAARRLGTKSAEVAARVSVALTPFAFLCIALAALSNPPFLAPLIWLWTGLVLYALSTAFAVSCMTSIGANRAPGAARGAVLGTLRSLGALARAAGPLLTSSVYWYSGAAITYAIGSLILIIPTVMLFRLKT

Description

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.

Subunit

Component of some SAGA transcription coactivator-HAT complexes. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).

Similarity

Belongs to the SGF11 family.

Uniprot

H9JBX5   S4PY92   A0A194PHZ0   A0A212FB43   A0A2H1V980   A0A3S2NKC9   + More
A0A194QTJ4   A0A2A4IZ64   A0A2M4A4L3   A0A2M4A4C0   A0A2M4A4A1   A0A182UM90   Q7PXG3   A0A1Y9J0E3   A0A2C9GQS7   A0A2M4BLW3   A0A2M4BLQ4   A0A2M4A4J0   A0A2M3Z112   A0A1I8JUR5   A0A2M4CXW2   A0A2M4CY87   A0A182TGI6   A0A182QB66   B0W8L3   A0A0P6ITW3   W5JLJ4   A0A182SIF7   A0A182GS40   A0A182H0F2   A0A182M1J2   A0A182F791   A0A1Q3F335   A0A067RGV1   A0A0K8TQS2   A0A023ESS4   A0A182J595   A0A1B6HN27   A0A182K7Q3   A0A1J1HWJ0   A0A182P2H5   A0A182YGF4   W8AMU6   A0A151IQD5   W8BKM7   T1IC98   A0A1B6DG21   A0A182VR85   A0A1I8PU65   A0A0A1XIW1   A0A1B6MES3   E2BNI5   A0A1S3IDZ8   E0VPH8   A0A146L5V7   A0A034WS73   A0A1S3JJA4   A0A1A9W9E4   A0A0K8W250   A0A336KJD8   A0A158NU74   B3M2W1   A0A1A9XSW5   B4NH55   A0A1W4VYE7   B3P060   A0A154PFE2   A0A0M3QXE0   E2AP83   A0A2A3ECD1   B4IKK9   A0A0L7QKN9   A0A088AEX5   B4PQA8   A0A0L0CK32   B4R146   F4WR53   Q9V395   A0A195BAT0   A0A1W4XGC5   A0A2S2NT42   A0A151WES6   A0A026WC47   A0A151J3K3   A0A310SAF0   A0A0C9QZH3   U4TUC5   N6UR19   A0A0N0BJX6   J3JVL6   B4KDL8   B4JFI9   J9K662   A0A2S2QMP6   E9IHJ8   A0A0K8UD20   A0A3B0KI59   A0A195FKS5   A0A0C9QSG0  

Pubmed

19121390    23622113    26354079    22118469    12364791    26999592    + More
20920257    23761445    26483478    24845553    26369729    24945155    25244985    24495485    25830018    20798317    20566863    26823975    25348373    21347285    17994087    17550304    26108605    21719571    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    24508170    23537049    22516182    21282665   

EMBL

BABH01014826    BABH01014827    BABH01014828    GAIX01003693    JAA88867.1    KQ459603    + More
KPI93036.1    AGBW02009379    OWR50956.1    ODYU01001340    SOQ37385.1    RSAL01000374    RVE42128.1    KQ461137    KPJ08787.1    NWSH01004560    PCG64929.1    GGFK01002341    MBW35662.1    GGFK01002335    MBW35656.1    GGFK01002306    MBW35627.1    AAAB01008987    EAA01105.4    APCN01000860    GGFJ01004843    MBW53984.1    GGFJ01004844    MBW53985.1    GGFK01002396    MBW35717.1    GGFM01001453    MBW22204.1    GGFL01005992    MBW70170.1    GGFL01005993    MBW70171.1    AXCN02001179    DS231859    EDS39063.1    GDUN01000667    JAN95252.1    ADMH02001070    ETN64178.1    JXUM01083846    KQ563400    KXJ73893.1    JXUM01101235    KQ564634    KXJ71981.1    AXCM01004258    GFDL01013073    JAV21972.1    KK852478    KDR23002.1    GDAI01000896    JAI16707.1    GAPW01001260    JAC12338.1    GECU01031627    JAS76079.1    CVRI01000026    CRK92355.1    GAMC01016450    JAB90105.1    KQ976780    KYN08374.1    GAMC01016451    JAB90104.1    ACPB03019764    GEDC01012702    JAS24596.1    GBXI01003341    JAD10951.1    GEBQ01005592    JAT34385.1    GL449414    EFN82764.1    DS235366    EEB15284.1    GDHC01016023    GDHC01013066    JAQ02606.1    JAQ05563.1    GAKP01002344    JAC56608.1    GDHF01007379    JAI44935.1    UFQS01000524    UFQT01000524    SSX04599.1    SSX24962.1    ADTU01026284    CH902617    EDV43491.1    CH964272    EDW84552.1    CH954181    EDV48296.1    KQ434892    KZC10555.1    CP012526    ALC45763.1    GL441481    EFN64756.1    KZ288287    PBC29395.1    CH480853    EDW51613.1    KQ414940    KOC59179.1    CM000160    EDW96217.1    JRES01000301    KNC32572.1    CM000364    EDX12133.1    GL888284    EGI63280.1    AF181656    AE014297    AAD55441.1    AAF55849.1    KQ976532    KYM81643.1    GGMR01007297    MBY19916.1    KQ983238    KYQ46354.1    KK107323    EZA52604.1    KQ980298    KYN16845.1    KQ777939    OAD52031.1    GBYB01001110    JAG70877.1    KB631669    ERL85164.1    APGK01020125    KB740167    ENN81197.1    KQ435710    KOX79804.1    BT127284    AEE62246.1    CH933806    EDW13852.1    CH916369    EDV93470.1    ABLF02031955    GGMS01009765    MBY78968.1    GL763289    EFZ19934.1    GDHF01028074    JAI24240.1    OUUW01000007    SPP83408.1    KQ981512    KYN40862.1    GBYB01006669    JAG76436.1   

Proteomes

UP000005204    UP000053268    UP000007151    UP000283053    UP000053240    UP000218220    + More
UP000075903    UP000007062    UP000076407    UP000075840    UP000075900    UP000075902    UP000075886    UP000002320    UP000000673    UP000075901    UP000069940    UP000249989    UP000075883    UP000069272    UP000027135    UP000075880    UP000075881    UP000183832    UP000075885    UP000076408    UP000078542    UP000015103    UP000075920    UP000095300    UP000008237    UP000085678    UP000009046    UP000091820    UP000005205    UP000007801    UP000092443    UP000007798    UP000192221    UP000008711    UP000076502    UP000092553    UP000000311    UP000242457    UP000001292    UP000053825    UP000005203    UP000002282    UP000037069    UP000000304    UP000007755    UP000000803    UP000078540    UP000192223    UP000075809    UP000053097    UP000078492    UP000030742    UP000019118    UP000053105    UP000009192    UP000001070    UP000007819    UP000268350    UP000078541   

PRIDE

H9JBX5    Q9V395   

Pfam

PF14645   Chibby        + More
PF07690   MFS_1
PF08209   Sgf11

Interpro

IPR028118   Chibby_fam        + More
IPR011701   MFS       
IPR036259   MFS_trans_sf       
IPR020846   MFS_dom       
IPR001958   Tet-R_TetA/multi-R_MdtG       
IPR005829   Sugar_transporter_CS       
IPR013246   SAGA_su_Sgf11       

SUPFAM

SSF103473   SSF103473       

CDD

cd06174  MFS

ProteinModelPortal

H9JBX5   S4PY92   A0A194PHZ0   A0A212FB43   A0A2H1V980   A0A3S2NKC9   + More
A0A194QTJ4   A0A2A4IZ64   A0A2M4A4L3   A0A2M4A4C0   A0A2M4A4A1   A0A182UM90   Q7PXG3   A0A1Y9J0E3   A0A2C9GQS7   A0A2M4BLW3   A0A2M4BLQ4   A0A2M4A4J0   A0A2M3Z112   A0A1I8JUR5   A0A2M4CXW2   A0A2M4CY87   A0A182TGI6   A0A182QB66   B0W8L3   A0A0P6ITW3   W5JLJ4   A0A182SIF7   A0A182GS40   A0A182H0F2   A0A182M1J2   A0A182F791   A0A1Q3F335   A0A067RGV1   A0A0K8TQS2   A0A023ESS4   A0A182J595   A0A1B6HN27   A0A182K7Q3   A0A1J1HWJ0   A0A182P2H5   A0A182YGF4   W8AMU6   A0A151IQD5   W8BKM7   T1IC98   A0A1B6DG21   A0A182VR85   A0A1I8PU65   A0A0A1XIW1   A0A1B6MES3   E2BNI5   A0A1S3IDZ8   E0VPH8   A0A146L5V7   A0A034WS73   A0A1S3JJA4   A0A1A9W9E4   A0A0K8W250   A0A336KJD8   A0A158NU74   B3M2W1   A0A1A9XSW5   B4NH55   A0A1W4VYE7   B3P060   A0A154PFE2   A0A0M3QXE0   E2AP83   A0A2A3ECD1   B4IKK9   A0A0L7QKN9   A0A088AEX5   B4PQA8   A0A0L0CK32   B4R146   F4WR53   Q9V395   A0A195BAT0   A0A1W4XGC5   A0A2S2NT42   A0A151WES6   A0A026WC47   A0A151J3K3   A0A310SAF0   A0A0C9QZH3   U4TUC5   N6UR19   A0A0N0BJX6   J3JVL6   B4KDL8   B4JFI9   J9K662   A0A2S2QMP6   E9IHJ8   A0A0K8UD20   A0A3B0KI59   A0A195FKS5   A0A0C9QSG0  

PDB

3WDO     E-value=3.77568e-06,     Score=121

KEGG

101741986    no KO assigned | (RefSeq) major facilitator superfamily domain-containing protein 10-like

GO

GO:0016021   GO:0055085   GO:0005215   GO:0031526   GO:0016578   GO:0045893   GO:0008270   GO:0003713   GO:0071819   GO:0000124   GO:0005694   GO:0006265   GO:0003917   GO:0006418   GO:0003723   GO:0046872   GO:0003824  

Subcellular location

Nucleus  

Length:

421

Number of predicted TMHs:

10

Exp number of AAs in TMHs:

211.2295

Exp number, first 60 AAs:

14.00599

Total prob of N-in:

0.42171

POSSIBLE N-term signal

sequence

outside

1  -  46

TMhelix

47  -  69

inside

70  -  80

TMhelix

81  -  98

outside

99  -  102

TMhelix

103  -  125

inside

126  -  137

TMhelix

138  -  160

outside

161  -  174

TMhelix

175  -  193

inside

194  -  240

TMhelix

241  -  263

outside

264  -  277

TMhelix

278  -  296

inside

297  -  302

TMhelix

303  -  325

outside

326  -  328

TMhelix

329  -  351

inside

352  -  391

TMhelix

392  -  414

outside

415  -  421

 

 

Pi

208.414142

Theta

137.169609

Tajima's D

0.26904

CLR

0.002938

CSRT

0.449977501124944

Interpretation

Uncertain