Gene

KWMTBOMO10418

Pre Gene Modal

BGIBMGA007080

Annotation

PREDICTED:_rRNA_methyltransferase_2?_mitochondrial_[Papilio_polytes]

Location

Bomo_Chr17(+):10640284-10642002      View in EpiBrowser

Full name

rRNA methyltransferase 2, mitochondrial      

Alternative Name

rRNA (uridine-2'-O)-methyltransferase

Location in the cell

Mitochondrial   Reliability : 2.398

CDS

ATGCTTTGTTCGCATCGAGAAGTGACGCATATCAAATTGAATTACACGAGAATGTGCTTCTTAGTGAATTGTCTAAAAAGATTTAAAAGTTCACAAGAATGGCTGAGTCGTCAAAAGGCTGATCCTTATGTAGAGAAAGCTAAGATATACAACTATAGATGTCGCAGTGCCTTCAAATTATTGGAGATGAATGAAAGAACCAATATATTGAGACCTGGCCTAGCTGTTATTGATCTTGGAGCATGTCCCGGTTCTTGGACGCAAGTGGCGGTTCAGAAAACAAATGCGGATGGTGCAGATCCTAGTAAGCCCAAGGGAACAGTCTTGTCAATTGATAAACTTCAGATTTTTCCTATTCAGGGAGCAACAATACTAAATAACATGGATTTCTCTACAATTGAAGCACATGACAAAGTTGTAGAAGTTTTAAATGGCCAACAAGTTGATCTAGTTCTCTCTGACATGGCTCCCAGTGCAACAGGTGTCCGGGAATTGGATAAAGATAGAATAATTGGTCTCTGTTACATGGCTATCAGATTTGCAGCACTTGTGACAAAAAGAGAAGGAAATTTACTATTTAAAGTATGGGATGGAAAAGAAGTTCCTATACTAGAAATGGATTTAGCAAGGTTTTATAAGAATATAAAGATATTAAAGCCGATGGCAAGCAGGACTGAATCTTCAGAAAAGTTTATTTTAGCAAAGGGATTCAAGGGGATACAGAGACCTTTACAAAATGGCAGATGGGGTTGA

Protein

MLCSHREVTHIKLNYTRMCFLVNCLKRFKSSQEWLSRQKADPYVEKAKIYNYRCRSAFKLLEMNERTNILRPGLAVIDLGACPGSWTQVAVQKTNADGADPSKPKGTVLSIDKLQIFPIQGATILNNMDFSTIEAHDKVVEVLNGQQVDLVLSDMAPSATGVRELDKDRIIGLCYMAIRFAALVTKREGNLLFKVWDGKEVPILEMDLARFYKNIKILKPMASRTESSEKFILAKGFKGIQRPLQNGRWG

Description

S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1579 (Um1579) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA.

Catalytic Activity

a uridine in rRNA + S-adenosyl-L-methionine = a 2'-O-methyluridine in rRNA + H(+) + S-adenosyl-L-homocysteine

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

Keywords

Complete proteome   Methyltransferase   Mitochondrion   Reference proteome   rRNA processing   S-adenosyl-L-methionine   Transferase   Transit peptide  

Feature

chain  rRNA methyltransferase 2, mitochondrial

Uniprot

H9JC35   A0A0L7KUK3   A0A194PJ07   A0A194QTD1   A0A212F0S3   S4P8C4   + More
A0A1Q3FGX1   B0W330   Q16QF4   A0A2A4J0J3   A0A1I8NE31   A0A232FKL9   A0A084VBR9   K7IZI4   A0A2P8YY69   A0A182YSD8   B3LXS3   A0A2J7QN05   A0A2R7VZL4   W5JUN1   A0A1B0BLV9   A0A1A9Y8J1   E9IQA8   A0A026WVI2   A0A182XJ46   A0A1A9VAE4   A0A154PRT1   A0A0L0CHB3   A0A182L7B0   D6WYW4   T1DU58   Q7QB53   A0A182QUS8   A0A182I7R5   A0A182P6R9   A0A1B0FQT1   A0A0C9R8E9   A0A182VJ31   A0A182W1G8   A0A182JTD0   A0A1Y1LBB9   A0A182NLC9   A0A0M4ENT7   A0A1I8PYJ7   F5HL46   A0A182LS23   A0A0J7KZ80   A0A182U4D2   E2ANP9   A0A3B0JNI6   A0A182RYP5   B4IV03   B4GMN5   B3P080   B4PNK4   Q9VDT6   A0A1W4VXH1   B4QST8   A0A0N0BCN8   A0A195CYH7   B4JT12   Q294S6   W8C1M3   A0A0L7QV70   B4IHR8   A0A0K8SBI6   B4K4S3   A0A2A3E7L8   B4NEY9   A0A146M257   X1WLQ5   A0A1S3D6B1   A0A1S4EFC6   A0A1A9WJ71   A0A2H8TU79   A0A0P4VHN9   R4FJT4   A0A0A9YYJ6   B4M4R8   A0A2S2P7K5   A0A195BU54   A0A158NKP8   A0A195EJ81   A0A034VKW6   A0A195F4R1   F4WD06   A0A0K8VUB2   A0A023F7T0   A0A310SGG9   A0A088AEE5   A0A151X8F0   N6UGP9   A0A0V0GB01   A0A1B6CF18   A0A182JGN7   A0A1W4XS80   E2BQR2   A0A2S2R587  

EC Number

2.1.1.-

Pubmed

19121390    26227816    26354079    22118469    23622113    17510324    + More
25315136    28648823    24438588    20075255    29403074    25244985    17994087    20920257    23761445    21282665    24508170    30249741    26108605    20966253    18362917    19820115    12364791    14747013    17210077    28004739    20798317    17550304    10731132    12537572    12537569    25009282    15632085    24495485    26823975    27129103    25401762    21347285    25348373    21719571    25474469    23537049   

EMBL

BABH01014821    JTDY01005699    KOB66731.1    KQ459603    KPI93033.1    KQ461137    + More
KPJ08783.1    AGBW02011057    OWR47301.1    GAIX01009565    JAA82995.1    GFDL01008239    JAV26806.1    DS231830    EDS30738.1    CH477750    EAT36622.1    NWSH01004560    PCG64932.1    NNAY01000090    OXU31080.1    ATLV01009141    KE524507    KFB35413.1    PYGN01000290    PSN49184.1    CH902617    EDV41730.1    NEVH01013201    PNF29971.1    KK854104    PTY11355.1    ADMH02000319    ETN66983.1    JXJN01016583    JXJN01016584    JXJN01016585    JXJN01016586    GL764688    EFZ17244.1    KK107087    QOIP01000001    EZA59998.1    RLU27177.1    KQ435012    KZC13820.1    JRES01000405    KNC31640.1    KQ971363    EFA09016.2    GAMD01000444    JAB01147.1    AAAB01008880    EAA08541.4    AXCN02000121    APCN01002549    CCAG010014772    GBYB01004320    JAG74087.1    GEZM01062524    GEZM01062522    GEZM01062520    GEZM01062519    GEZM01062517    GEZM01062516    JAV69640.1    CP012526    ALC47340.1    EGK97007.1    AXCM01003760    LBMM01001891    KMQ95598.1    GL441295    EFN64935.1    OUUW01000008    SPP83705.1    CH892421    EDX00217.1    CH479185    EDW38109.1    CH954181    EDV48454.1    CM000160    EDW96067.1    AE014297    AY071418    CM000364    EDX12298.1    KQ435908    KOX68972.1    KQ977110    KYN05725.1    CH916373    EDV94902.1    CM000070    EAL28888.3    GAMC01010991    JAB95564.1    KQ414734    KOC62341.1    CH480840    EDW49435.1    GBRD01015164    GDHC01006439    JAG50662.1    JAQ12190.1    CH933806    EDW16076.2    KZ288355    PBC27216.1    CH964251    EDW83364.1    GDHC01004758    JAQ13871.1    ABLF02003617    GFXV01005991    MBW17796.1    GDKW01002504    JAI54091.1    ACPB03000203    GAHY01002148    JAA75362.1    GBHO01008994    JAG34610.1    CH940652    EDW59629.1    GGMR01012766    MBY25385.1    KQ976403    KYM92112.1    ADTU01002112    KQ978801    KYN28320.1    GAKP01016779    JAC42173.1    KQ981805    KYN35570.1    GL888077    EGI67913.1    GDHF01009866    JAI42448.1    GBBI01001415    JAC17297.1    KQ770367    OAD52660.1    KQ982431    KYQ56558.1    APGK01036043    KB740932    KB632408    ENN77827.1    ERL95122.1    GECL01001104    JAP05020.1    GEDC01025254    JAS12044.1    GL449798    EFN81981.1    GGMS01016004    MBY85207.1   

Proteomes

UP000005204    UP000037510    UP000053268    UP000053240    UP000007151    UP000002320    + More
UP000008820    UP000218220    UP000095301    UP000215335    UP000030765    UP000002358    UP000245037    UP000076408    UP000007801    UP000235965    UP000000673    UP000092460    UP000092443    UP000053097    UP000279307    UP000076407    UP000078200    UP000076502    UP000037069    UP000075882    UP000007266    UP000007062    UP000075886    UP000075840    UP000075885    UP000092444    UP000075903    UP000075920    UP000075881    UP000075884    UP000092553    UP000095300    UP000075883    UP000036403    UP000075902    UP000000311    UP000268350    UP000075900    UP000002282    UP000008744    UP000008711    UP000000803    UP000192221    UP000000304    UP000053105    UP000078542    UP000001070    UP000001819    UP000053825    UP000001292    UP000009192    UP000242457    UP000007798    UP000007819    UP000079169    UP000091820    UP000015103    UP000008792    UP000078540    UP000005205    UP000078492    UP000078541    UP000007755    UP000005203    UP000075809    UP000019118    UP000030742    UP000075880    UP000192223    UP000008237   

PRIDE

H9JC35    Q9VDT6   

Pfam

PF01728   FtsJ

Interpro

IPR002877   rRNA_MeTrfase_FtsJ_dom        + More
IPR015507   rRNA-MeTfrase_E       
IPR029063   SAM-dependent_MTases       

SUPFAM

SSF53335   SSF53335       

ProteinModelPortal

H9JC35   A0A0L7KUK3   A0A194PJ07   A0A194QTD1   A0A212F0S3   S4P8C4   + More
A0A1Q3FGX1   B0W330   Q16QF4   A0A2A4J0J3   A0A1I8NE31   A0A232FKL9   A0A084VBR9   K7IZI4   A0A2P8YY69   A0A182YSD8   B3LXS3   A0A2J7QN05   A0A2R7VZL4   W5JUN1   A0A1B0BLV9   A0A1A9Y8J1   E9IQA8   A0A026WVI2   A0A182XJ46   A0A1A9VAE4   A0A154PRT1   A0A0L0CHB3   A0A182L7B0   D6WYW4   T1DU58   Q7QB53   A0A182QUS8   A0A182I7R5   A0A182P6R9   A0A1B0FQT1   A0A0C9R8E9   A0A182VJ31   A0A182W1G8   A0A182JTD0   A0A1Y1LBB9   A0A182NLC9   A0A0M4ENT7   A0A1I8PYJ7   F5HL46   A0A182LS23   A0A0J7KZ80   A0A182U4D2   E2ANP9   A0A3B0JNI6   A0A182RYP5   B4IV03   B4GMN5   B3P080   B4PNK4   Q9VDT6   A0A1W4VXH1   B4QST8   A0A0N0BCN8   A0A195CYH7   B4JT12   Q294S6   W8C1M3   A0A0L7QV70   B4IHR8   A0A0K8SBI6   B4K4S3   A0A2A3E7L8   B4NEY9   A0A146M257   X1WLQ5   A0A1S3D6B1   A0A1S4EFC6   A0A1A9WJ71   A0A2H8TU79   A0A0P4VHN9   R4FJT4   A0A0A9YYJ6   B4M4R8   A0A2S2P7K5   A0A195BU54   A0A158NKP8   A0A195EJ81   A0A034VKW6   A0A195F4R1   F4WD06   A0A0K8VUB2   A0A023F7T0   A0A310SGG9   A0A088AEE5   A0A151X8F0   N6UGP9   A0A0V0GB01   A0A1B6CF18   A0A182JGN7   A0A1W4XS80   E2BQR2   A0A2S2R587  

PDB

2NYU     E-value=2.20936e-50,     Score=500

KEGG

101741458    K02427 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] | (RefSeq) rRNA methyltransferas

GO

GO:0008168   GO:0001510   GO:0051301   GO:0008650   GO:0005739   GO:0006364   GO:0032259   GO:0006563   GO:0030170   GO:0016740   GO:0006418   GO:0003723   GO:0046872   GO:0003824  

Subcellular location

Mitochondrion  

Length:

250

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.03791

Exp number, first 60 AAs:

0.0005

Total prob of N-in:

0.08005

outside

1  -  250

 

 

Pi

346.640649

Theta

235.958352

Tajima's D

1.46771

CLR

0.022907

CSRT

0.779861006949653

Interpretation

Possibly Positive selection