Gene

KWMTBOMO10406

Annotation

PREDICTED:_CDP-diacylglycerol--glycerol-3-phosphate_3-phosphatidyltransferase?_mitochondrial_[Bombyx_mori]

Location

Bomo_Chr17(-):10398332-10403273      View in EpiBrowser

Full name

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase      

Location in the cell

Cytoplasmic   Reliability : 1.582 Nuclear   Reliability : 1.779

CDS

ATGAAACTATACATAGTTGATGACAGAGTTTTACTGAGCGGTGCAAATTGTTCAAATGACTACTTCATGCAGAGACAAGACCGCTATATAGAAATAGATGATCCTGATCTTGCCAACTTCTATAGAGACATTATAGATGAGGTGAGCAAATACAGCAAAAGATGTGAGAATCAAGATATTGTTAGTGATAAGAAATTGACAAAAGAGAAAATGATTCAAGATATGAAGAATAATATTTGTAATGTCATATATAAGTGGCAGCAGTTGCAGCTCTCAAAATTGTCTACAAGTGGAGATTCAAGTTTGGACACTTGGGTGTTCCCACTCATACAAATGGGAGAGTTCAACATAACACAAGATGAATATGTTACTAGAAAGTTGATGGTGTCCGCGCCAAAAGGCTCTCACCTACAACTTGCAACTGGATATTTTAATCTCACAGAGCAATATACGCGGACGCTTCTCGATCAATGTAAAGCAAATGTAAGCCTGTTAATGGCACATCCAAATGCTAACGGCTTTCTGGGAGCTGCGGGACCAGCAGGAGGAATACCATTTGCATATTCGTTAATAGCTAAACAATTTTGGCAAAGGGTTGTTGATTCGAATCAAGCAAGTCGAATAAGGATGTTAGAATATGAACGTCCTGGGTGGACGTTTCACGCGAAAGGCTTATGGTACTACCCGCCGGGTAGCGACGTGCCGTGGGCCACTGTAATAGGGTCTGCGAATCTCGGGGAGCGATCGGTGAAACGCGACCTCGAAGCCCAAGCCGCCATTTTCACCGTATCACCTGAATTACAGGCGAGGCTTCAGCAAGAGACCAAGAGACTACACAGTTACTCTAAAGAGTGCGGAGAGGAGCTTTTATCTAGAGAAACTCCGAAGTGGGTGCGTGCGACAGTCAAACTGTTCAGAACATACTTTTAA

Protein

MKLYIVDDRVLLSGANCSNDYFMQRQDRYIEIDDPDLANFYRDIIDEVSKYSKRCENQDIVSDKKLTKEKMIQDMKNNICNVIYKWQQLQLSKLSTSGDSSLDTWVFPLIQMGEFNITQDEYVTRKLMVSAPKGSHLQLATGYFNLTEQYTRTLLDQCKANVSLLMAHPNANGFLGAAGPAGGIPFAYSLIAKQFWQRVVDSNQASRIRMLEYERPGWTFHAKGLWYYPPGSDVPWATVIGSANLGERSVKRDLEAQAAIFTVSPELQARLQQETKRLHSYSKECGEELLSRETPKWVRATVKLFRTYF

Description

Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.

Catalytic Activity

a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+)

Similarity

Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
Belongs to the peptidase S1 family.

Uniprot

A0A194QTH9   A0A194PPF8   A0A2A4IUX5   A0A2H1X2Y9   A0A1E1WM00   A0A212FGA8   + More
A0A0K8TM35   A0A1B0AHJ3   A0A1A9WRL4   A0A0A1WMN5   A0A1B0GE11   A0A1A9XR36   A0A034WC33   A0A1B0BBE8   A0A1A9VM55   A0A0K8W0F5   B4K7V3   W5J5T7   B4I253   W8BVT3   Q16F09   A0A023EW14   B4JRV9   A0A1S4G3N2   A0A1W4UBQ2   B4LX11   A0A0L0BUV5   A0A182HA29   B4G5T9   B3P3B2   A0A2M4BK10   A0A182NR97   Q299W5   A0A2M3ZAH1   A0A182FAH0   Q8SYL0   B4QTZ2   A0A0M4ENV7   B4NFA2   A0A1I8NZX6   B3M1U7   B4PM15   A0A182P3V6   A0A182QZN9   A0A182UG12   A0A182Y6Q8   A0A182MHQ1   A0A182XAI4   Q7QCJ7   A0A182HSC4   A0A2M4AGD2   A0A3B0JI55   A0A182UTP1   A0A1I8JVJ0   A0A182SUZ1   A0A182JTT8   A0A2M4AFS4   A0A182IVG8   A0A182VZY5   B0W3D2   A0A1I8M804   A0A084W715   A0A1Q3FBB1   A0A1W4WFR0   A0A1B0DQC2   A0A1Y1LHD3   U5EVQ7   N6T1J5   A0A1L8DZ75   A0A1B0GH91   A0A146LH60   A0A2M3Z9I5   A0A1J1HWS8   A0A0V0GA47   A0A154P3A9   A0A182RQL2   A0A069DZ15   A0A336MA29   A0A088AC75   A0A2J7RSK8   A0A2A3EPI8   K7J1X4   A0A023F0Y0   A0A0T6AXA7   A0A2J7RSJ8   A0A2R7WVE8   A0A0M8ZR38   E2BS37   D6WWG3   E9FXT8   A0A0L7RF40   A0A151J3U5   A0A026X5D7   A0A3L8DI65   A0A369S6E6   B3RPT8   A0A1B6E7I1   A0A0P5YGU8   A0A0P4Z8B0   A0A0P4YG54  

EC Number

2.7.8.5

Pubmed

26354079    22118469    26369729    25830018    25348373    17994087    + More
20920257    23761445    24495485    17510324    24945155    26108605    26483478    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    25244985    12364791    14747013    17210077    25315136    24438588    28004739    23537049    26823975    26334808    20075255    25474469    20798317    18362917    19820115    21292972    24508170    30249741    30042472    18719581   

EMBL

KQ461137    KPJ08772.1    KQ459603    KPI93020.1    NWSH01007108    PCG63084.1    + More
ODYU01013035    SOQ59675.1    GDQN01003178    JAT87876.1    AGBW02008703    OWR52743.1    GDAI01002608    JAI14995.1    GBXI01014366    GBXI01006374    GBXI01005211    GBXI01003362    JAC99925.1    JAD07918.1    JAD09081.1    JAD10930.1    CCAG010012080    GAKP01007594    GAKP01007593    JAC51358.1    JXJN01011418    GDHF01012837    GDHF01008009    GDHF01007937    JAI39477.1    JAI44305.1    JAI44377.1    CH933806    EDW16474.1    ADMH02002037    ETN59812.1    CH480820    EDW54610.1    GAMC01005522    JAC01034.1    CH478533    EAT32818.1    GAPW01001074    JAC12524.1    CH916373    EDV94499.1    CH940650    EDW67758.2    JRES01001300    KNC23811.1    JXUM01030949    JXUM01030950    KQ560903    KXJ80410.1    CH479179    EDW24955.1    CH954181    EDV48564.1    GGFJ01004203    MBW53344.1    CM000070    EAL27586.2    GGFM01004778    MBW25529.1    AE014297    AY071478    AAF55593.2    AAL49100.1    CM000364    EDX12415.1    CP012526    ALC46438.1    CH964251    EDW82969.1    CH902617    EDV42207.1    CM000160    EDW95947.1    AXCN02001467    AXCM01008428    AAAB01008859    EAA08154.4    APCN01000261    GGFK01006520    MBW39841.1    OUUW01000005    SPP80393.1    GGFK01006305    MBW39626.1    DS231831    EDS31275.1    ATLV01021093    KE525312    KFB46009.1    GFDL01010208    JAV24837.1    AJVK01019040    GEZM01055258    JAV73062.1    GANO01003301    JAB56570.1    APGK01047774    KB741089    KB632382    ENN73939.1    ERL94170.1    GFDF01002355    JAV11729.1    AJWK01004085    GDHC01012333    JAQ06296.1    GGFM01004411    MBW25162.1    CVRI01000021    CRK91812.1    GECL01001230    JAP04894.1    KQ434796    KZC05620.1    GBGD01001430    JAC87459.1    UFQT01000554    SSX25227.1    NEVH01000254    PNF43818.1    KZ288210    PBC32951.1    GBBI01003545    JAC15167.1    LJIG01022592    KRT79754.1    PNF43816.1    KK855687    PTY23534.1    KQ435970    KOX67809.1    GL450143    EFN81492.1    KQ971361    EFA08139.1    GL732526    EFX88232.1    KQ414608    KOC69434.1    KQ980246    KYN17115.1    KK107019    EZA62629.1    QOIP01000007    RLU20145.1    NOWV01000062    RDD42082.1    DS985242    EDV27697.1    GEDC01003433    JAS33865.1    GDIP01059601    JAM44114.1    GDIP01216629    JAJ06773.1    GDIP01228088    JAI95313.1   

Proteomes

UP000053240    UP000053268    UP000218220    UP000007151    UP000092445    UP000091820    + More
UP000092444    UP000092443    UP000092460    UP000078200    UP000009192    UP000000673    UP000001292    UP000008820    UP000001070    UP000192221    UP000008792    UP000037069    UP000069940    UP000249989    UP000008744    UP000008711    UP000075884    UP000001819    UP000069272    UP000000803    UP000000304    UP000092553    UP000007798    UP000095300    UP000007801    UP000002282    UP000075885    UP000075886    UP000075902    UP000076408    UP000075883    UP000076407    UP000007062    UP000075840    UP000268350    UP000075903    UP000075901    UP000075881    UP000075880    UP000075920    UP000002320    UP000095301    UP000030765    UP000192223    UP000092462    UP000019118    UP000030742    UP000092461    UP000183832    UP000076502    UP000075900    UP000005203    UP000235965    UP000242457    UP000002358    UP000053105    UP000008237    UP000007266    UP000000305    UP000053825    UP000078492    UP000053097    UP000279307    UP000253843    UP000009022   

PRIDE

Q8SYL0   

Pfam

PF13091   PLDc_2        + More
PF01758   SBF
PF00089   Trypsin

Interpro

IPR016270   PGS1        + More
IPR001736   PLipase_D/transphosphatidylase       
IPR025202   PLD-like_dom       
IPR038770   Na+/solute_symporter_sf       
IPR002657   BilAc:Na_symport/Acr3       
IPR009003   Peptidase_S1_PA       
IPR001314   Peptidase_S1A       
IPR018114   TRYPSIN_HIS       
IPR001254   Trypsin_dom       

SUPFAM

SSF50494   SSF50494       

Gene 3D

1.20.1530.20    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

A0A194QTH9   A0A194PPF8   A0A2A4IUX5   A0A2H1X2Y9   A0A1E1WM00   A0A212FGA8   + More
A0A0K8TM35   A0A1B0AHJ3   A0A1A9WRL4   A0A0A1WMN5   A0A1B0GE11   A0A1A9XR36   A0A034WC33   A0A1B0BBE8   A0A1A9VM55   A0A0K8W0F5   B4K7V3   W5J5T7   B4I253   W8BVT3   Q16F09   A0A023EW14   B4JRV9   A0A1S4G3N2   A0A1W4UBQ2   B4LX11   A0A0L0BUV5   A0A182HA29   B4G5T9   B3P3B2   A0A2M4BK10   A0A182NR97   Q299W5   A0A2M3ZAH1   A0A182FAH0   Q8SYL0   B4QTZ2   A0A0M4ENV7   B4NFA2   A0A1I8NZX6   B3M1U7   B4PM15   A0A182P3V6   A0A182QZN9   A0A182UG12   A0A182Y6Q8   A0A182MHQ1   A0A182XAI4   Q7QCJ7   A0A182HSC4   A0A2M4AGD2   A0A3B0JI55   A0A182UTP1   A0A1I8JVJ0   A0A182SUZ1   A0A182JTT8   A0A2M4AFS4   A0A182IVG8   A0A182VZY5   B0W3D2   A0A1I8M804   A0A084W715   A0A1Q3FBB1   A0A1W4WFR0   A0A1B0DQC2   A0A1Y1LHD3   U5EVQ7   N6T1J5   A0A1L8DZ75   A0A1B0GH91   A0A146LH60   A0A2M3Z9I5   A0A1J1HWS8   A0A0V0GA47   A0A154P3A9   A0A182RQL2   A0A069DZ15   A0A336MA29   A0A088AC75   A0A2J7RSK8   A0A2A3EPI8   K7J1X4   A0A023F0Y0   A0A0T6AXA7   A0A2J7RSJ8   A0A2R7WVE8   A0A0M8ZR38   E2BS37   D6WWG3   E9FXT8   A0A0L7RF40   A0A151J3U5   A0A026X5D7   A0A3L8DI65   A0A369S6E6   B3RPT8   A0A1B6E7I1   A0A0P5YGU8   A0A0P4Z8B0   A0A0P4YG54  

KEGG

101740252    K00995 CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] | (RefSeq) C

PATHWAY

00564    Glycerophospholipid metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0008444   GO:0005739   GO:0032049   GO:0005524   GO:0016021   GO:0004252   GO:0006655  

PANTHER

PTHR12586  

Subcellular location

Mitochondrion  

Length:

309

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.19282

Exp number, first 60 AAs:

0

Total prob of N-in:

0.08517

outside

1  -  309

 

 

Pi

149.304605

Theta

173.098576

Tajima's D

-0.437889

CLR

183.357769

CSRT

0.260486975651217

Interpretation

Uncertain