Gene
KWMTBOMO10392
Pre Gene Modal
BGIBMGA007036
Annotation
PREDICTED:_serine/threonine-protein_kinase_ATR_[Bombyx_mori]
Full name
Serine/threonine-protein kinase ATR
Alternative Name
Ataxia telangiectasia and Rad3-related protein homolog
Meiotic protein 41
Meiotic protein 41
Location in the cell
Nuclear Reliability : 1.917
Sequence
CDS
ATGGAAGATGACTACCAGGATGGACCATTCACAGTGTGGCAAAAGCTTAATGAACCTACTGTGGTTTTATTTAATAATCTAGAACATGCTGTAGATGGGCTGGACCGATTAATAACATCAATTTTAAAATTTTCTGGAGATTTTTCAGAGGATTTAGTTCCAAGAGTTGGTTACGAAAAATACCCTGAAGTCTACTATAGTGCATTTAATACATGGTTAATTGGAAGGCTATTTTACATTTGGTCAGAGGAATACCTTCTTAGAATACACACAGCAAGTAAAGATGCTCAGTTAAAAATATTGAACATATTATGTATTGTTAAGAATTATAAGACTGTTGGCATTGCCAAATTTCAATATATTTTTGCTGACGAATTCAGAGAAGTGCTAAATTGTCTAGAAGCTATTGTTCACTCCTTAGAAAATTTCTATGAGCAAGGTGAAATAGACAATATCTACATTAAAGATATAAATAAAGAGAAAATGAATTTTAAAAGTGAAGTTATTGAACTATGTCCCTTGTTACAATTAAACAAAACATATTCAGCAAGTAGATTAATTGGAGATGTTTTAATGCCATGTTTCCTAAGTAAGGATCACCACATACAGGCACAAGAAGACATATCAACATCTTCTAATCAATCCACAATAGCTGGTTTACAGTCTTTATTGATAAAATTTTTGAATTACAAGCAGTATGTTGATATGAAAAATGTGGGTGTTTGGAATCTTCTGCAATGCTTGAGTTTTCATTTTGATGTATTCAAATATAACGGCCCAAAAGAACTAATTTGTGAAGAAAATATTGAGTCAATTTTGGAAGTATTTAAACCATTTAATGAGGATTTGCAGGACAATGATGAAGAGTTGAATTCACGGAAGGATGTGTTTTTTATTACAAGTGTAAATTTACTTGCAAGTTATACAAAATCTAGTTTGGAGAGCAATAACCTTGGGAATCAAACAAAAGCTCTAAATATGATAGTAGATTTAGGAATGTGCCGAAATGAAAAAGTTATTTTGCCCACAACTAAATTATTGATCTATTTTATAATGCATCCCCAATGTCCTGTTGGACCTAAAGCCGTTGTGTATTTGAGAGATATCTGTGAAGCTCATGAATATACTTCAAACCAGGTTTACCACAGATATAAAAAAGACTACTGTCGCCTTTTTGTTGAATGCAGCTTATATAATGGGAAAGATTTCGCCTTGGCCCTTTCCAAAGTTGTTAGGGCATTTGGATTCGTTGGTTACCGCGATTTTATATCAAAAGATGTTCGCCATTTCCTTCCTTATCTGATGCCTTACTCTGTGACCATCAAAGAAGTGCCTTCAATGATTGAAGAATTTGCATCTTTAGTGCAGTTTCCTGTTTCGGATTTTTTGATCAAGAGCTTTGCTCATATTTATGTTTACCTTTATTTGAATGAAACGGATTCCGTCTCGTCTAAATGCTACAAAATTATCGAAAGATTAACGAAAACTACAATATCTAATCTAATAAATAAGCATTTCAGAATAATACTGACAGAGTTTTTGTTGCAATACTGTTCTTGTCCTGAAAAAGTACTAAACGCGTGTAGGTACCTAGCATGCCACGATCCTGATGTGTCTACTCCGACTGGTACAATGAGTATGAGTACCTCTCAAATAGCCGACTTCTTAAATCCAAAGTTCTTAGGAGTGTTGGCTTACTTTGATCACAATTTAGTCAATGCTAAAGTAGCGCAATCTGTAAAAAGGAAAGCGTTAAAAAGCTTTCCCGATATAATGCAATTAATGGGTGTGAAATACATAACCCCTCTGCGTTTCAAAGTTTTAGCGACGCTGCGATCGGCCTTGCCGTTGGCTAAAGAATATCCCAACATTTTAGCTGAAGCTTGGAGTGCTTTTATACATCAAATTGATAGTGCTGCATTAGGGCCTTTGTTATCGAATTTAGCAGTATCATTACTCCAGCAAATTGAATACGCACGCCAAGAAGTAAACCAGATCTTTCATTATCTGGTCATAAATAACGAAAATTTACTTAGCCGCCACATATCTGATCTGTTCTTTGTAGAAGATACCCAAATATCAGATAGGATAAAAACAGTAATCAAAATGCACGTAAAAAGGACTCAGCCTGACGGATTCCTGGACAAAATTGAATGGTATCTTAATCAACTTAATCAGAACATTCCAATGATTAAAGTGTACACTTTTAAACATTTAAACAAATTGTTGAAGAATAATCGAACGGAAATTCATAAAGCTATATTTGGTGGGAAAAACATAGATCCCGTCATCGTGAATCTAATGGACTCTTTATTGATGGGCTGTAAAGACACAGATCCTCAAGTGAGCGAAGCCAGCGGTTCTTGTTTAGGGCAGCTAGGCGCAATAGAAGCGGGACACTTACCACGTCAATATGTAAAACCAGACAAATCGCCTTTTGCCTTCTCCATAGTAGACGATTGTTTTACTACAGCCGCTTTAATGGAACTTACTAGAGCTTTTCAGTATGAAAAGGACACTAAGAATATGGATTGCTACGCATTTACCATTCAGGAGATATTAAAGATTTATGATATATCACCTTATGGAAAGAAAAGGGATGTTTGGAACAGTTTCCCCGAAAACAAGCATCAAATTATGTATCCTTTGCTCAGTTCAAGGTATATGTTAACAAATCCATCGCAACCCGAAAAAACACATCCGCTTTTCGGTTCTTCTTACGCAACCACATTTCTCGAATGGGCGCACAATTGGGCGGCTCAGCTGATTCCGCTTATTGAGACTGACAGCGTCCGCGAATTATTGCGCAAAGTACATCCAAGCCTAAAGTATGACGTCAGCACTTTATTCCTGTTCCTACCCTATGTGTTGCTCCACGCTGTCATGTTCAAAGCAAACCACCAGTATATACAGGAAGAAATGATGGCTGTCATCGGTTTGGACAATGTTGAACAAATAGATGAAGTAACAGAACGTTCTAAGCACGGAATGTTGCGACACATCAGAACGACACCCAGTATTGGCACAGTACAAGCTGAAGAAGGAAATGAGAGTAAATGCAGCAAGACTACTTACGCGTTATTGGATTTCCTGAATAGATGGCTCTTGGAATGGGCTCATTCAAAACAAGGATCACTGGAGCACGATAATTATAAAACTATAAATTCGTTTGTCAAAAAATTCAATAAGCTCACAATAGCCCGTGGAAAATTCGCTTGCGGCGAATTAGAGAGGGCGTTACAATACTTGGAGTTGTATATAGAGGAAACCGATCGAATGCAAGAACAATTGCCTTTCATGGCTGAAATATACGCGTTATTAGACGAACCGGACTCTATTGCTGGTATAGTTTCTCTGAAGAGATCAGAGCCGTCGTTGAAAGAATTAATTTTAGTTCAGGCAGTGACAGGTCGTTTGCAAGACGCCGCATTATGTTACGAACGTATTGCCCAAGAGGGACAGTTGGACAGATCCAGTCTACAGGGTATGATAGACTGCTATCTAGGCTTAGATCAGCCGTTCACGGCGTACCGCTTGATAAGCGAGCACGAAGCTGAAGATATGACGGAACTAGCTGCGGAGCCGCTCTGGCGATTGGGACGCTTCGAGCAGCTCGAGGAGCTGGTCAGCCAACCTGTGCCAATTTGCAAAGAAAACTGGGGTGTGGTCATGGGTCGATTGCTACTAGCGTACAGGAAACAAGATCACGACAACTTCGTTGTGTGTTGCAAAGACGCTACCGTGAGATTGTTAGCGCAAATGGACGGCGAGAGCAAAGGCGAGAGCGCATTGCGGAGCGGCTACCAGAGCGTGCTCGGACTCCACATAGTTACTGAAGTCGAACACGCTGAGGAGGTTCTACGCAGGCTGAAAGAGTTGCAAGACGGGGATAGACGGAGCAATGTAATCATAAATCAGTTGTTAGACGAATGGCGTCGTCGTATTTCGGTTGTGCAGTCCGACGTACGAACCATCGAACCCTTGTTGAGGTTGAGAAGAATTGTTTTACAGCAAGCGAAGGAGATCCTCGAACCAAGTCATCCGATGACCGCGAATACGTTGAAATCGTTTATAGGTGACCTGTGGCTGCAGAGTGCGAAGCACGCGAGGAAAGCTGGTATTTTCCAACAGGCCTACATGTATATATTGAATGCCGAAGAATACCATCCCGAGGAATTGTTTATTGAAAAATCTAAAATGTACTGGGCCCGCGGACAGAACGAGCAAGCGTTCATAACGTTGAGGCGCGGCCTTGAAGACTCTTATCCCGCTATTGAAACGCTTTCCAAGGAACAGAGAAAAATATGCGCCAAAGCCAAACTGCTGATAGCGAAATACAACGACGAAACCTCAAACGTCGACGTAGATGTCAATATCGGGTACTACAAAGAGTCAGTGGAAGTTTTCAATCAATGGGAAAAAAGTTTGGTAAGTTTGGGCGCCTACTACGAGAAGGTGAGCAGCAGTGAGACCGTAAAGTCTCCTACGGAAATGTGGGCGCGCCGTACACTAGCACTGAATAGCTACGGGAAAGCTTTGCAATACGGCCATAAGTATTTATATCAGAGCATGCCGCGGATGTTGTCTATATGGCTCGACGTTGAGGTGACGGCGTCGGATTCTAGCATGCACTCAGTATTGGCTGAAATGACAGACATCATCAAGAGTTATTCGGAGCGATTACCTCTGTATCTTTATTTGACGGCCTTCTCGCAGATCGTATCAAGGATATGTCATCCCGTCCAAGAGGTTTACAAACAATTAAAAGCGATAATAGTGAAGTTGATAAAGGCGTATCCGCATCACGCGCTTTGGATGATGATGTGCGTGATGAAGTCCGGCTACCCGCAGCGCAAGAAGCGGTGCGCGGACGTGTTCTCTGAGCCGGCGCTGCGCGACGGGGCGCTCGTGCGGCTCGTCGGCGACTTCACGCTGCTCGCCGAGAGACTCATCGAGCTCTGCAACAAGCCCATCGCCGGAAACGCGTCGACCACTACAGTCTCGAGCTTGGTACGATCGTTACCCGTTTGTCTAACAAATGGAAAATTCAGCCACATTATGATGCCGTTCCAAGATTTCTGCAAGATAGTACTACCTTCAAAAGCAGCCAGACAAGAAAGACTCGACTTCAACATACCCACGGAACCGCCGGTTTACATAGCCGGGATAAAAGAACATATAAGTATATTACCGTCCCTACAGAAGCCTAGGAAAGTGACGTTAATAGGGTCAGACGGAAAAGATTACATAATAATGCTGAAGCCTCGTGACGACCTTCGCAAGGATTATCGATTGATGGAATTCAACGGAGTGGTGAACCGGTTCTTGCAAGATGCTCCCGAAACACGCAAACGTCGCCTGTACATCCGCACGTACTGCGTCCTGCCGCTTAACGAGGAGTGCGGACTCATTGAATGGGTACCGAATCTCGTTGGCTTAAGGCCTATATTGATACACATTTACAAGCAAAAAGGTATGCACACTAGTAATAAAGAATTAAAGGAGATGATGTGCACAACTAAAGATCCCGTTGAAAAGAAAAGGAGAATATTCGAAGATCAACTGCTACCTCGTCATCCTCCAGTCCTCCAAGAATGGTTCAGAGGTGTATTTTCGGATCCTTATGGATGGTATCAAGCCAGATCGGCGTACATAAGGACGGCTGCAGTTATGTCTATGGTCGGATATATTTTAGGTTTGGGCGATCGTCACGGAGAGAACATATCCTTCGATTCGACGAATGGCGACACCGTGCACGTTGATTTCAACTGTTTGTTCAACCGAGGGGAGAGGTTCGAATGGCCCGAGAGAGTGCCCTTCAGATTGACTCACAACATGGAGGCCGCTATGGGTCCTCTGAAACACGAAGGAATGTTCAGGAAGAGCTGCGAAGCCGTAATGCGGGTGCTGCGCTCGCAAACGGCCGCCCTGATGTCCGTCATAGATCCGTTTGTGTACGACCCGCTCGTGTCGTGGGGGCGCGCCAACCGGGCACCGGACTGCGGGGAGCGGACCAACGAGCAGGCCATGCAGCATCTGCAGCAAATACGGCAGAGACTCAACGGAATGGTGAGAACAAAGAACAAACAACCGTCACTCTTATCTCCAGAGGGACAAGTGGAGCATCTTATCGTCGAGGCCACCAGCATACACAATCTATGCCAAATGTACATCGGATGGGGACCGTTTTTGTAA
Protein
MEDDYQDGPFTVWQKLNEPTVVLFNNLEHAVDGLDRLITSILKFSGDFSEDLVPRVGYEKYPEVYYSAFNTWLIGRLFYIWSEEYLLRIHTASKDAQLKILNILCIVKNYKTVGIAKFQYIFADEFREVLNCLEAIVHSLENFYEQGEIDNIYIKDINKEKMNFKSEVIELCPLLQLNKTYSASRLIGDVLMPCFLSKDHHIQAQEDISTSSNQSTIAGLQSLLIKFLNYKQYVDMKNVGVWNLLQCLSFHFDVFKYNGPKELICEENIESILEVFKPFNEDLQDNDEELNSRKDVFFITSVNLLASYTKSSLESNNLGNQTKALNMIVDLGMCRNEKVILPTTKLLIYFIMHPQCPVGPKAVVYLRDICEAHEYTSNQVYHRYKKDYCRLFVECSLYNGKDFALALSKVVRAFGFVGYRDFISKDVRHFLPYLMPYSVTIKEVPSMIEEFASLVQFPVSDFLIKSFAHIYVYLYLNETDSVSSKCYKIIERLTKTTISNLINKHFRIILTEFLLQYCSCPEKVLNACRYLACHDPDVSTPTGTMSMSTSQIADFLNPKFLGVLAYFDHNLVNAKVAQSVKRKALKSFPDIMQLMGVKYITPLRFKVLATLRSALPLAKEYPNILAEAWSAFIHQIDSAALGPLLSNLAVSLLQQIEYARQEVNQIFHYLVINNENLLSRHISDLFFVEDTQISDRIKTVIKMHVKRTQPDGFLDKIEWYLNQLNQNIPMIKVYTFKHLNKLLKNNRTEIHKAIFGGKNIDPVIVNLMDSLLMGCKDTDPQVSEASGSCLGQLGAIEAGHLPRQYVKPDKSPFAFSIVDDCFTTAALMELTRAFQYEKDTKNMDCYAFTIQEILKIYDISPYGKKRDVWNSFPENKHQIMYPLLSSRYMLTNPSQPEKTHPLFGSSYATTFLEWAHNWAAQLIPLIETDSVRELLRKVHPSLKYDVSTLFLFLPYVLLHAVMFKANHQYIQEEMMAVIGLDNVEQIDEVTERSKHGMLRHIRTTPSIGTVQAEEGNESKCSKTTYALLDFLNRWLLEWAHSKQGSLEHDNYKTINSFVKKFNKLTIARGKFACGELERALQYLELYIEETDRMQEQLPFMAEIYALLDEPDSIAGIVSLKRSEPSLKELILVQAVTGRLQDAALCYERIAQEGQLDRSSLQGMIDCYLGLDQPFTAYRLISEHEAEDMTELAAEPLWRLGRFEQLEELVSQPVPICKENWGVVMGRLLLAYRKQDHDNFVVCCKDATVRLLAQMDGESKGESALRSGYQSVLGLHIVTEVEHAEEVLRRLKELQDGDRRSNVIINQLLDEWRRRISVVQSDVRTIEPLLRLRRIVLQQAKEILEPSHPMTANTLKSFIGDLWLQSAKHARKAGIFQQAYMYILNAEEYHPEELFIEKSKMYWARGQNEQAFITLRRGLEDSYPAIETLSKEQRKICAKAKLLIAKYNDETSNVDVDVNIGYYKESVEVFNQWEKSLVSLGAYYEKVSSSETVKSPTEMWARRTLALNSYGKALQYGHKYLYQSMPRMLSIWLDVEVTASDSSMHSVLAEMTDIIKSYSERLPLYLYLTAFSQIVSRICHPVQEVYKQLKAIIVKLIKAYPHHALWMMMCVMKSGYPQRKKRCADVFSEPALRDGALVRLVGDFTLLAERLIELCNKPIAGNASTTTVSSLVRSLPVCLTNGKFSHIMMPFQDFCKIVLPSKAARQERLDFNIPTEPPVYIAGIKEHISILPSLQKPRKVTLIGSDGKDYIIMLKPRDDLRKDYRLMEFNGVVNRFLQDAPETRKRRLYIRTYCVLPLNEECGLIEWVPNLVGLRPILIHIYKQKGMHTSNKELKEMMCTTKDPVEKKRRIFEDQLLPRHPPVLQEWFRGVFSDPYGWYQARSAYIRTAAVMSMVGYILGLGDRHGENISFDSTNGDTVHVDFNCLFNRGERFEWPERVPFRLTHNMEAAMGPLKHEGMFRKSCEAVMRVLRSQTAALMSVIDPFVYDPLVSWGRANRAPDCGERTNEQAMQHLQQIRQRLNGMVRTKNKQPSLLSPEGQVEHLIVEATSIHNLCQMYIGWGPFL
Summary
Description
Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination. Phosphorylates grp/CHK1. Phosphorylates 'Ser-137' of histone variant H2AX/H2AV at sites of DNA damage, thereby regulating DNA damage response mechanism. Essential for the DNA damage checkpoint in larval imaginal disks and neuroblasts and for the DNA replication checkpoint in the embryo. Has also an essential role during early nuclear divisions in embryos, where it is required to delay mitosis in response to incomplete DNA replication. Also plays an important role during meiosis, where it may monitor double-strand-break repair during meiotic crossing over, to regulate the progression of prophase I, and to enforce metaphase I delay observed at the end of oogenesis.
Catalytic Activity
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]
Cofactor
Mn(2+)
Subunit
Interacts with mus304.
Similarity
Belongs to the PI3/PI4-kinase family.
Belongs to the PI3/PI4-kinase family. ATM subfamily.
Belongs to the PI3/PI4-kinase family. ATM subfamily.
Keywords
ATP-binding
Complete proteome
Developmental protein
DNA damage
DNA repair
DNA-binding
Kinase
Manganese
Nucleotide-binding
Nucleus
Phosphoprotein
Reference proteome
Repeat
Transferase
Feature
chain Serine/threonine-protein kinase ATR
Uniprot
H9JBZ1
A0A194PI47
A0A212FIV4
A0A0N1IAI7
A0A3S2NN67
A0A1W4WXP6
+ More
A0A2Z5TRJ4 A0A139WD77 A0A0L7RD72 A0A0N0BJU1 U4UWE8 A0A1Y1KZQ7 A0A1S4FP55 A0A2A3E7S3 Q16TZ4 A0A182GZK0 A0A3L8E1Z7 F4W728 A0A1Q3EXR3 K7IPT4 A0A087ZSF9 A0A026WV78 A0A154P3A0 A0A195AXQ5 A0A158NS73 E2AYL1 B0W656 A0A1B0GK21 A0A195F5I7 A0A195C1T1 A0A195DAZ0 A0A151X7X4 A0A182W7X4 A0A182YDY1 A0A182K3Q7 A0A182RSA0 A0A182PNU9 E2BQQ0 Q7Q0G1 A0A182HML1 A0A182J801 A0A336KU49 A0A182NNV9 A0A182TC53 A0A182FLY5 A0A0A1WFS4 A0A0L0C880 A0A0K8VPA7 W8C8V5 A0A2S2P889 A0A2H8TV48 J9JYZ5 A0A1A9WZ82 E0V919 A0A1B0ASG1 A0A1A9XAY9 A0A1A9Z1U1 A0A1A9UXZ6 A0A1B0G1I3 A0A1B6CK79 A0A1I8QD74 E9GRN4 B4KFM4 A0A3S0ZVD3 E9GRN5 B4JR21 B4LQK6 B4PXS9 Q9VXG8 B3MDS4 A0A1S3K481 A0A1S3K4T8 A0A0P6HD71 A0A0N8EJG3 F7E9U4 B3NX43 A0A0P6C5N5 A0A162EDE1 G1SGC5 A0A3B0JNT3 A0A2K5SGU6 A0A2K5SGU2 B5DMV1 B4H061 A0A3B4UCT7 A0A2K6UHP7 A0A3B4YTE7 A0A2C9L8I9 A0A1V4K3Y3 A0A210QB87 A0A1V4K3P2 A0A091H0P1 A0A3Q1CTD3 A0A3Q0GXR4 A0A1U8D727 A0A091R055 A0A091CTV2
A0A2Z5TRJ4 A0A139WD77 A0A0L7RD72 A0A0N0BJU1 U4UWE8 A0A1Y1KZQ7 A0A1S4FP55 A0A2A3E7S3 Q16TZ4 A0A182GZK0 A0A3L8E1Z7 F4W728 A0A1Q3EXR3 K7IPT4 A0A087ZSF9 A0A026WV78 A0A154P3A0 A0A195AXQ5 A0A158NS73 E2AYL1 B0W656 A0A1B0GK21 A0A195F5I7 A0A195C1T1 A0A195DAZ0 A0A151X7X4 A0A182W7X4 A0A182YDY1 A0A182K3Q7 A0A182RSA0 A0A182PNU9 E2BQQ0 Q7Q0G1 A0A182HML1 A0A182J801 A0A336KU49 A0A182NNV9 A0A182TC53 A0A182FLY5 A0A0A1WFS4 A0A0L0C880 A0A0K8VPA7 W8C8V5 A0A2S2P889 A0A2H8TV48 J9JYZ5 A0A1A9WZ82 E0V919 A0A1B0ASG1 A0A1A9XAY9 A0A1A9Z1U1 A0A1A9UXZ6 A0A1B0G1I3 A0A1B6CK79 A0A1I8QD74 E9GRN4 B4KFM4 A0A3S0ZVD3 E9GRN5 B4JR21 B4LQK6 B4PXS9 Q9VXG8 B3MDS4 A0A1S3K481 A0A1S3K4T8 A0A0P6HD71 A0A0N8EJG3 F7E9U4 B3NX43 A0A0P6C5N5 A0A162EDE1 G1SGC5 A0A3B0JNT3 A0A2K5SGU6 A0A2K5SGU2 B5DMV1 B4H061 A0A3B4UCT7 A0A2K6UHP7 A0A3B4YTE7 A0A2C9L8I9 A0A1V4K3Y3 A0A210QB87 A0A1V4K3P2 A0A091H0P1 A0A3Q1CTD3 A0A3Q0GXR4 A0A1U8D727 A0A091R055 A0A091CTV2
EC Number
2.7.11.1
Pubmed
19121390
26354079
22118469
26760975
18362917
19820115
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23537049 28004739 17510324 26483478 30249741 21719571 20075255 24508170 21347285 20798317 25244985 12364791 25830018 26108605 24495485 20566863 21292972 17994087 17550304 7671309 14729967 10731132 12537572 10209095 11676920 12361566 12689597 12807779 14711410 15860729 18327897 29746464 21993624 15632085 15562597 28812685
23537049 28004739 17510324 26483478 30249741 21719571 20075255 24508170 21347285 20798317 25244985 12364791 25830018 26108605 24495485 20566863 21292972 17994087 17550304 7671309 14729967 10731132 12537572 10209095 11676920 12361566 12689597 12807779 14711410 15860729 18327897 29746464 21993624 15632085 15562597 28812685
EMBL
BABH01014763
BABH01014764
BABH01014765
BABH01014766
KQ459603
KPI92992.1
+ More
AGBW02008324 OWR53666.1 KQ460328 KPJ15649.1 RSAL01000218 RVE44087.1 FX985839 BBA93726.1 KQ971361 KYB25791.1 KQ414615 KOC68701.1 KQ435711 KOX79522.1 KB632399 ERL94616.1 GEZM01073296 JAV65175.1 KZ288340 PBC27755.1 CH477636 EAT38000.1 JXUM01099673 JXUM01099674 JXUM01099675 KQ564510 KXJ72154.1 QOIP01000001 RLU26750.1 GL887802 EGI70018.1 GFDL01014940 JAV20105.1 KK107087 EZA59955.1 KQ434796 KZC05824.1 KQ976716 KYM76820.1 ADTU01002214 ADTU01002215 ADTU01002216 ADTU01002217 ADTU01002218 GL443930 EFN61462.1 DS231847 EDS36403.1 AJWK01022514 KQ981805 KYN35646.1 KQ978344 KYM94834.1 KQ981042 KYN10085.1 KQ982431 KYQ56485.1 GL449798 EFN81969.1 AAAB01008985 EAA15175.4 APCN01006606 UFQS01001061 UFQT01001061 SSX08766.1 SSX28678.1 GBXI01016982 JAC97309.1 JRES01000772 KNC28437.1 GDHF01021381 GDHF01011602 JAI30933.1 JAI40712.1 GAMC01007176 JAB99379.1 GGMR01013025 MBY25644.1 GFXV01006301 MBW18106.1 ABLF02010940 DS234988 EEB09875.1 JXJN01002755 JXJN01026254 CCAG010002137 GEDC01023527 JAS13771.1 GL732560 EFX77801.1 CH933807 EDW13139.2 RQTK01000227 RUS83841.1 EFX77802.1 CH916372 EDV99351.1 CH940649 EDW64463.1 CM000162 EDX01915.1 U34925 AY282465 AE014298 CH902619 EDV36459.1 GDIQ01030349 JAN64388.1 GDIQ01020764 JAN73973.1 CH954180 EDV46872.1 GDIP01005469 JAM98246.1 LRGB01002076 KZS09380.1 AAGW02015209 AAGW02015210 OUUW01000001 SPP72878.1 CH379064 EDY72758.2 CH479200 EDW29656.1 LSYS01004732 OPJ79101.1 NEDP02004329 OWF45999.1 OPJ79100.1 KL448071 KFO79887.1 KK709768 KFQ32579.1 KN124268 KFO21862.1
AGBW02008324 OWR53666.1 KQ460328 KPJ15649.1 RSAL01000218 RVE44087.1 FX985839 BBA93726.1 KQ971361 KYB25791.1 KQ414615 KOC68701.1 KQ435711 KOX79522.1 KB632399 ERL94616.1 GEZM01073296 JAV65175.1 KZ288340 PBC27755.1 CH477636 EAT38000.1 JXUM01099673 JXUM01099674 JXUM01099675 KQ564510 KXJ72154.1 QOIP01000001 RLU26750.1 GL887802 EGI70018.1 GFDL01014940 JAV20105.1 KK107087 EZA59955.1 KQ434796 KZC05824.1 KQ976716 KYM76820.1 ADTU01002214 ADTU01002215 ADTU01002216 ADTU01002217 ADTU01002218 GL443930 EFN61462.1 DS231847 EDS36403.1 AJWK01022514 KQ981805 KYN35646.1 KQ978344 KYM94834.1 KQ981042 KYN10085.1 KQ982431 KYQ56485.1 GL449798 EFN81969.1 AAAB01008985 EAA15175.4 APCN01006606 UFQS01001061 UFQT01001061 SSX08766.1 SSX28678.1 GBXI01016982 JAC97309.1 JRES01000772 KNC28437.1 GDHF01021381 GDHF01011602 JAI30933.1 JAI40712.1 GAMC01007176 JAB99379.1 GGMR01013025 MBY25644.1 GFXV01006301 MBW18106.1 ABLF02010940 DS234988 EEB09875.1 JXJN01002755 JXJN01026254 CCAG010002137 GEDC01023527 JAS13771.1 GL732560 EFX77801.1 CH933807 EDW13139.2 RQTK01000227 RUS83841.1 EFX77802.1 CH916372 EDV99351.1 CH940649 EDW64463.1 CM000162 EDX01915.1 U34925 AY282465 AE014298 CH902619 EDV36459.1 GDIQ01030349 JAN64388.1 GDIQ01020764 JAN73973.1 CH954180 EDV46872.1 GDIP01005469 JAM98246.1 LRGB01002076 KZS09380.1 AAGW02015209 AAGW02015210 OUUW01000001 SPP72878.1 CH379064 EDY72758.2 CH479200 EDW29656.1 LSYS01004732 OPJ79101.1 NEDP02004329 OWF45999.1 OPJ79100.1 KL448071 KFO79887.1 KK709768 KFQ32579.1 KN124268 KFO21862.1
Proteomes
UP000005204
UP000053268
UP000007151
UP000053240
UP000283053
UP000192223
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UP000007266 UP000053825 UP000053105 UP000030742 UP000242457 UP000008820 UP000069940 UP000249989 UP000279307 UP000007755 UP000002358 UP000005203 UP000053097 UP000076502 UP000078540 UP000005205 UP000000311 UP000002320 UP000092461 UP000078541 UP000078542 UP000078492 UP000075809 UP000075920 UP000076408 UP000075881 UP000075900 UP000075885 UP000008237 UP000007062 UP000075840 UP000075880 UP000075884 UP000075901 UP000069272 UP000037069 UP000007819 UP000091820 UP000009046 UP000092460 UP000092443 UP000092445 UP000078200 UP000092444 UP000095300 UP000000305 UP000009192 UP000271974 UP000001070 UP000008792 UP000002282 UP000000803 UP000007801 UP000085678 UP000008225 UP000008711 UP000076858 UP000001811 UP000268350 UP000233040 UP000001819 UP000008744 UP000261420 UP000233220 UP000261360 UP000076420 UP000190648 UP000242188 UP000053760 UP000257160 UP000189705 UP000028990
UP000007266 UP000053825 UP000053105 UP000030742 UP000242457 UP000008820 UP000069940 UP000249989 UP000279307 UP000007755 UP000002358 UP000005203 UP000053097 UP000076502 UP000078540 UP000005205 UP000000311 UP000002320 UP000092461 UP000078541 UP000078542 UP000078492 UP000075809 UP000075920 UP000076408 UP000075881 UP000075900 UP000075885 UP000008237 UP000007062 UP000075840 UP000075880 UP000075884 UP000075901 UP000069272 UP000037069 UP000007819 UP000091820 UP000009046 UP000092460 UP000092443 UP000092445 UP000078200 UP000092444 UP000095300 UP000000305 UP000009192 UP000271974 UP000001070 UP000008792 UP000002282 UP000000803 UP000007801 UP000085678 UP000008225 UP000008711 UP000076858 UP000001811 UP000268350 UP000233040 UP000001819 UP000008744 UP000261420 UP000233220 UP000261360 UP000076420 UP000190648 UP000242188 UP000053760 UP000257160 UP000189705 UP000028990
Pfam
Interpro
IPR036940
PI3/4_kinase_cat_sf
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IPR012993 UME
IPR016024 ARM-type_fold
IPR003151 PIK-rel_kinase_FAT
IPR000403 PI3/4_kinase_cat_dom
IPR018936 PI3/4_kinase_CS
IPR011009 Kinase-like_dom_sf
IPR014009 PIK_FAT
IPR003152 FATC_dom
IPR011990 TPR-like_helical_dom_sf
IPR011011 Znf_FYVE_PHD
IPR007863 Peptidase_M16_C
IPR011765 Pept_M16_N
IPR001431 Pept_M16_Zn_BS
IPR032632 Peptidase_M16_M
IPR011249 Metalloenz_LuxS/M16
IPR011989 ARM-like
IPR019734 TPR_repeat
IPR013026 TPR-contain_dom
IPR021133 HEAT_type_2
IPR012993 UME
IPR016024 ARM-type_fold
IPR003151 PIK-rel_kinase_FAT
IPR000403 PI3/4_kinase_cat_dom
IPR018936 PI3/4_kinase_CS
IPR011009 Kinase-like_dom_sf
IPR014009 PIK_FAT
IPR003152 FATC_dom
IPR011990 TPR-like_helical_dom_sf
IPR011011 Znf_FYVE_PHD
IPR007863 Peptidase_M16_C
IPR011765 Pept_M16_N
IPR001431 Pept_M16_Zn_BS
IPR032632 Peptidase_M16_M
IPR011249 Metalloenz_LuxS/M16
IPR011989 ARM-like
IPR019734 TPR_repeat
IPR013026 TPR-contain_dom
IPR021133 HEAT_type_2
SUPFAM
Gene 3D
ProteinModelPortal
H9JBZ1
A0A194PI47
A0A212FIV4
A0A0N1IAI7
A0A3S2NN67
A0A1W4WXP6
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A0A2Z5TRJ4 A0A139WD77 A0A0L7RD72 A0A0N0BJU1 U4UWE8 A0A1Y1KZQ7 A0A1S4FP55 A0A2A3E7S3 Q16TZ4 A0A182GZK0 A0A3L8E1Z7 F4W728 A0A1Q3EXR3 K7IPT4 A0A087ZSF9 A0A026WV78 A0A154P3A0 A0A195AXQ5 A0A158NS73 E2AYL1 B0W656 A0A1B0GK21 A0A195F5I7 A0A195C1T1 A0A195DAZ0 A0A151X7X4 A0A182W7X4 A0A182YDY1 A0A182K3Q7 A0A182RSA0 A0A182PNU9 E2BQQ0 Q7Q0G1 A0A182HML1 A0A182J801 A0A336KU49 A0A182NNV9 A0A182TC53 A0A182FLY5 A0A0A1WFS4 A0A0L0C880 A0A0K8VPA7 W8C8V5 A0A2S2P889 A0A2H8TV48 J9JYZ5 A0A1A9WZ82 E0V919 A0A1B0ASG1 A0A1A9XAY9 A0A1A9Z1U1 A0A1A9UXZ6 A0A1B0G1I3 A0A1B6CK79 A0A1I8QD74 E9GRN4 B4KFM4 A0A3S0ZVD3 E9GRN5 B4JR21 B4LQK6 B4PXS9 Q9VXG8 B3MDS4 A0A1S3K481 A0A1S3K4T8 A0A0P6HD71 A0A0N8EJG3 F7E9U4 B3NX43 A0A0P6C5N5 A0A162EDE1 G1SGC5 A0A3B0JNT3 A0A2K5SGU6 A0A2K5SGU2 B5DMV1 B4H061 A0A3B4UCT7 A0A2K6UHP7 A0A3B4YTE7 A0A2C9L8I9 A0A1V4K3Y3 A0A210QB87 A0A1V4K3P2 A0A091H0P1 A0A3Q1CTD3 A0A3Q0GXR4 A0A1U8D727 A0A091R055 A0A091CTV2
A0A2Z5TRJ4 A0A139WD77 A0A0L7RD72 A0A0N0BJU1 U4UWE8 A0A1Y1KZQ7 A0A1S4FP55 A0A2A3E7S3 Q16TZ4 A0A182GZK0 A0A3L8E1Z7 F4W728 A0A1Q3EXR3 K7IPT4 A0A087ZSF9 A0A026WV78 A0A154P3A0 A0A195AXQ5 A0A158NS73 E2AYL1 B0W656 A0A1B0GK21 A0A195F5I7 A0A195C1T1 A0A195DAZ0 A0A151X7X4 A0A182W7X4 A0A182YDY1 A0A182K3Q7 A0A182RSA0 A0A182PNU9 E2BQQ0 Q7Q0G1 A0A182HML1 A0A182J801 A0A336KU49 A0A182NNV9 A0A182TC53 A0A182FLY5 A0A0A1WFS4 A0A0L0C880 A0A0K8VPA7 W8C8V5 A0A2S2P889 A0A2H8TV48 J9JYZ5 A0A1A9WZ82 E0V919 A0A1B0ASG1 A0A1A9XAY9 A0A1A9Z1U1 A0A1A9UXZ6 A0A1B0G1I3 A0A1B6CK79 A0A1I8QD74 E9GRN4 B4KFM4 A0A3S0ZVD3 E9GRN5 B4JR21 B4LQK6 B4PXS9 Q9VXG8 B3MDS4 A0A1S3K481 A0A1S3K4T8 A0A0P6HD71 A0A0N8EJG3 F7E9U4 B3NX43 A0A0P6C5N5 A0A162EDE1 G1SGC5 A0A3B0JNT3 A0A2K5SGU6 A0A2K5SGU2 B5DMV1 B4H061 A0A3B4UCT7 A0A2K6UHP7 A0A3B4YTE7 A0A2C9L8I9 A0A1V4K3Y3 A0A210QB87 A0A1V4K3P2 A0A091H0P1 A0A3Q1CTD3 A0A3Q0GXR4 A0A1U8D727 A0A091R055 A0A091CTV2
PDB
5YZ0
E-value=0,
Score=2517
Ontologies
PATHWAY
GO
GO:0005524
GO:0004674
GO:0000077
GO:0000723
GO:0005634
GO:0004222
GO:0046872
GO:0016301
GO:0000706
GO:0031000
GO:0045003
GO:0007131
GO:0033314
GO:0007088
GO:0030716
GO:0016321
GO:0030261
GO:0045002
GO:0007349
GO:0009314
GO:0001700
GO:0004672
GO:0007348
GO:0006302
GO:0016310
GO:0007093
GO:0003677
GO:0018105
GO:0007444
GO:0000076
GO:0006468
GO:0043517
GO:0071480
GO:0034644
GO:0032405
GO:0090399
GO:0032407
GO:0016605
GO:1904884
GO:0070198
GO:0005794
GO:0046777
GO:0097694
GO:0008156
GO:0035469
GO:0008630
GO:0003140
GO:1901207
GO:0060271
GO:0016021
GO:0005515
GO:0005488
GO:0006415
GO:0006418
GO:0003723
GO:0003824
Topology
Subcellular location
Nucleus
Length:
2064
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.256130000000001
Exp number, first 60 AAs:
0.00022
Total prob of N-in:
0.00421
outside
1 - 2064
Population Genetic Test Statistics
Pi
201.890514
Theta
172.840048
Tajima's D
-1.167815
CLR
1.585339
CSRT
0.110494475276236
Interpretation
Uncertain
