Gene

KWMTBOMO10380

Pre Gene Modal

BGIBMGA007063

Annotation

PREDICTED:_GPI_inositol-deacylase_[Amyelois_transitella]

Location

Bomo_Chr17(+):9279920-9294471      View in EpiBrowser

Full name

GPI inositol-deacylase      

Location in the cell

PlasmaMembrane   Reliability : 4.446

CDS

ATGTTTGAATATCCACAATTTGTGCATCTGTCTATGCCAGAAAACAAAATTTATCCACAATATGCCTTATTTGCATATAGTGAAGGCAGATTCACAGAGAGAGCAAGAAAAATGTGGTTTGACGGAGTACCAGTGTTATTCATACCAGGCAATTCTGGTAGTCACATGCAAGCAAGATCACTGGCATCTGTGGCCTTAAGAAAAGCCTTGTCTGGAGGATATGATTACCATTTTGATTACTTTGCCATAAGCTATAATGAGGAGCTCTCAGGCCTTTATGGAGGAGTTCTACAAAGTCAAACAAGATTTGCAGCTGCTTGTATAGAAAAAATATTGGATCTGTATAAAGAAAATAATTATATTAAATCTGTACCAACATCTGTTATCCTCATTGGACATTCAATGGGAGGTCTTGTAGCCAAGCGTTTGTTGGTTCATCCAAGTACAGTCAATTCGACAAGTATAGCAATCACTTTAGCAGCTCCTTTAGAAGCCCCACTGATTAACTTTGATATAGCTATGAATGATTACTATTTAAGTATGAATCATGAATGGGAAAATTTCGTAAGAGGCAATCAATTGATGACGGATAAGAAGATGCTTTTAAGTTTTGGAAATGGACCAAGAGATTTACTAATGCCTTCAGGCTTAACATTATCAAACGACAGTGATATAAATACATTGACAACAGCGATACCAGGCGTCTGGGTATCACCAGATCACGTCTGTATTGTATGGTGCAAGCAACTTGTTATGGCAATAAACAAATACCTATTTTCGATAGTTAATCCAATGACGAAACAAATAAGTTATGATAAACAGTTGCTAATGTCGAGAGCCAAGCAGTATTTTCAGGCGAATCGTTCAATGACAATTAATCCAGAAATTCCTAAAGCCAATGTGACTATGACAGCGGATGCGTTCTGGTACGAAGATAACCGGAGGATGTATCAAGTGCAACGACCGGAAATTGACAAAACAACATATCTAATGATAAGATTAGTTAAATTCCCGCAGAACAGATTCGTAGCTGTCGAGGCTGTTAATGTGTCTGATAAAGATTGGATATATGGATGTAACGCGAAACATACATACAACACGCACAGATATTGTAAACACGCAGTATCGTTAACAGAATTAAGTCGTTGGTCCGGAGCTGCGACCGAATTTCGAAAGAGGAAGTTAGCAACAGTGAACCTGCACAATGTGATGGAACATTACCCGGATTGGTCTCATGTTGTCGTCAAGGTATCGCCTACACGAAAACCCGTAACTATGAACATCGACATCAACGATTATGCGTCCCGGCAGATATTCGTGGATCTACCCACGTTTTTTGAATTCGGAAAGAGGATCGTGAAACCAGAAACCGAACGAGACAGTTTGTATTACGAATTGATCTTGCGAGATTTTAATGCGATACACGAAGCGTACCTCCTTTACGTTGAGCCGACTGCGAATTGTAAAGCAAGCCGATATCACGTTTCGGCGGAGTTGCATGTTCCGTGGGCGAAAAATCACGAATATTATCATTATTTTACGCATTTGAAAAGGTCGCCTATGAAGTTAAGGCTCTTTAAAACAAACCCTAATTTAACACTTGGGTTGGAAACCACCGAGCACGCGAAAATTACTTTGCTATTGGATCCTCAATGTCAATTTATTCTCAGTATATCGTCATCGTGGTACAATCGCCTCGCTCAGTTTACTCGAAATTACGGTCCAGTACTTATTCCGTATGTAGCCGCCATAGTGTTATTAGCTGCCAGAAGTATTATTATGAACTTTCAAGAATCTGGATCATGCTTGACCATTCATGGAGCTTTAATGAGCGAAGGCGTCAAACCCTATTATTGTCTCGTGTTTTCAAGATTAGCAACTAAGATTTTTTTGGCGATTCCGCTGTTCTCATTTATGTTCGAAAGCGCAAGCTGGAGGGATCTCGAATTGCAGTATTTTATCAAATCCCTGTTAGTGTTGCCAGCTTATATGACAGCATTAGGGATTGTCAATATTGTAGCTGCTGCTATAATGGGTGCAATGGTGTTTTCATCACAGATAGCGCATAGATTACTGTTTAAAATAGTATGGCGAGGCGGTGGTAGTTTAGCAGAGAAAATGGCCACCGGATTGCACAAGCTCCCCATGATCGTGAGTGCAGCGCTAGTTTGTGCGGTTCCTTTATCATGCGGAGCAGCTTCATTGGCTGCCGGTGCCGCATTTTATGCATTTATGCTCTCGAAAATGTATGAAGAATATTTAGAAGATTACGTTTACAAAATAATGGCAAAGCTAGCTTCTAAAGTCTGTCGTATGTTCAACTCGACAAGAAACAAATATGAAAAATCTGAAACCAATTTGATTTCAAAAGCTTTATCGGATGCAAAGGAAAGTAATCTCAGATCTAAAGAAATTGACGAAATTGAAGGTAATGATAAGGATTCAACGAACAATGTAGGACAAGACGGTTCTTCAAACACAGACTGTGCTTTAGTTTCTGCGAATAAAGAAAGCGAACGAAAGCCCAAAGAAGGCAGTATTAAAGGTGAAAGCAAAGACTTGGACGAGGATTTTAATAGCATTAACTTCCACATGATGTTGTTTTTCATGTGGATCACAGTAACTCTAGTCAATGTTCCAGCATTATTAACATGGGCGCGAAACTTTAAGTATTCCATGGTACTAAAACCAGATACGTCATATCACACTGGTCTAGTCATGTCAGTTTGTTCCAGTTGTATCTGGCAAATCAATGGTCCCAGAAGAAATTTGAAGCATTATGAAGCGGTTTCATCTTTACTATTTACAATGGCTATATTTATATTAGCTTTGGGACCCCTATCACTCACAATAGTCAACTATGGAATCACTTTCACATTTGTCGTTATTACATTACAACAAGTATGTGATAAGGAAGATGTTCAAAGTTCTACCATTGAAGGTACAAATGAATCCAAGAATGATAATGATGAAAAACCAAAAGAAAACCAAAAAGAAGAAGCTGATAATATTCAAACGAATGATTGTGATCCATGCAATGAGAACAGAATATTTGATGCTTTTAAGAATCTTCAAGATAAATTTGATTTAACTACAATGGATAATTTGTAA

Protein

MFEYPQFVHLSMPENKIYPQYALFAYSEGRFTERARKMWFDGVPVLFIPGNSGSHMQARSLASVALRKALSGGYDYHFDYFAISYNEELSGLYGGVLQSQTRFAAACIEKILDLYKENNYIKSVPTSVILIGHSMGGLVAKRLLVHPSTVNSTSIAITLAAPLEAPLINFDIAMNDYYLSMNHEWENFVRGNQLMTDKKMLLSFGNGPRDLLMPSGLTLSNDSDINTLTTAIPGVWVSPDHVCIVWCKQLVMAINKYLFSIVNPMTKQISYDKQLLMSRAKQYFQANRSMTINPEIPKANVTMTADAFWYEDNRRMYQVQRPEIDKTTYLMIRLVKFPQNRFVAVEAVNVSDKDWIYGCNAKHTYNTHRYCKHAVSLTELSRWSGAATEFRKRKLATVNLHNVMEHYPDWSHVVVKVSPTRKPVTMNIDINDYASRQIFVDLPTFFEFGKRIVKPETERDSLYYELILRDFNAIHEAYLLYVEPTANCKASRYHVSAELHVPWAKNHEYYHYFTHLKRSPMKLRLFKTNPNLTLGLETTEHAKITLLLDPQCQFILSISSSWYNRLAQFTRNYGPVLIPYVAAIVLLAARSIIMNFQESGSCLTIHGALMSEGVKPYYCLVFSRLATKIFLAIPLFSFMFESASWRDLELQYFIKSLLVLPAYMTALGIVNIVAAAIMGAMVFSSQIAHRLLFKIVWRGGGSLAEKMATGLHKLPMIVSAALVCAVPLSCGAASLAAGAAFYAFMLSKMYEEYLEDYVYKIMAKLASKVCRMFNSTRNKYEKSETNLISKALSDAKESNLRSKEIDEIEGNDKDSTNNVGQDGSSNTDCALVSANKESERKPKEGSIKGESKDLDEDFNSINFHMMLFFMWITVTLVNVPALLTWARNFKYSMVLKPDTSYHTGLVMSVCSSCIWQINGPRRNLKHYEAVSSLLFTMAIFILALGPLSLTIVNYGITFTFVVITLQQVCDKEDVQSSTIEGTNESKNDNDEKPKENQKEEADNIQTNDCDPCNENRIFDAFKNLQDKFDLTTMDNL

Description

Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.

Similarity

Belongs to the GPI inositol-deacylase family.

Feature

chain  GPI inositol-deacylase

Uniprot

A0A212FP83   A0A2H1VAP4   A0A0L7L106   A0A067QZ37   A0A1W4WDY2   U5EZS7   + More
A0A2J7R6B4   A0A336LRH5   A0A1J1HJN1   A0A1Y1N9E7   A0A1L8DUQ7   A0A1Q3G1I1   A0A1Q3G1J6   D6WW73   A0A1S4FY25   Q16K53   A0A182G874   A0A2P8XLK3   A0A182QD08   E0VHG5   A0A2M4BCT8   A0A2M4BCA0   A0A084VXD6   Q7PSQ5   V5GS79   W5JN50   A0A2M4AGP6   A0A182FLK3   A0A2M3Z242   A0A2M4AGR0   A0A2M3Z263   A0A146KTB8   A0A1I8N7F8   A0A182J144   A0A210QVH4   B4M812   A0A3B0KSD9   A0A1Y1N5V3   A0A0M9A5B9   B4H4F9   Q29I09   A0A088A5S0   W8BQ10   A0A0M4EP13   A0A3R7PVS9   B4JKJ5   A0A0P5Y5F1   A0A0P4Z516   A0A0P5B899   A0A0P5V869   U3JNW4   A0A0P5Q8S3   A0A0N8CCQ3   A0A0N8C2A5   A0A164K7R0   A0A0P6G1F3   A0A0P6HHW7   A0A0P6G852   V9K8G2   A0A1I8PZ32   A0A0P6CUV9   A0A0N8DVT0   A0A0K8U5B9   A0A0P4Z553   A0A0P4YXQ4   A0A0K8V6V2   A0A0P5Y2F6   A0A0P5N884   C3YRU1   A0A0A0AV20   A0A091VBE1   A0A026WKA5   A0A151WLQ7   A0A0P5IVF2   A0A2I0U480  

EC Number

3.1.-.-

Pubmed

22118469    26227816    24845553    28004739    18362917    19820115    + More
17510324    26483478    29403074    20566863    24438588    12364791    20920257    23761445    26823975    25315136    28812685    17994087    15632085    24495485    24402279    18563158    24508170    30249741   

EMBL

AGBW02003464    OWR55551.1    ODYU01001281    SOQ37284.1    JTDY01003687    KOB69147.1    + More
KK853176    KDR10287.1    GANO01000229    JAB59642.1    NEVH01006828    PNF36371.1    UFQS01000065    UFQT01000065    SSW98927.1    SSX19313.1    CVRI01000004    CRK87620.1    GEZM01012032    GEZM01012009    JAV93255.1    GFDF01003913    JAV10171.1    GFDL01001380    JAV33665.1    GFDL01001370    JAV33675.1    KQ971361    EFA08175.1    CH477976    EAT34679.1    JXUM01047499    KQ561521    KXJ78303.1    PYGN01001777    PSN32852.1    AXCN02002127    DS235170    EEB12821.1    GGFJ01001507    MBW50648.1    GGFJ01001506    MBW50647.1    ATLV01017988    KE525205    KFB42630.1    AAAB01008816    EAA05192.5    GALX01001457    JAB67009.1    ADMH02000630    ETN65551.1    GGFK01006642    MBW39963.1    GGFM01001820    MBW22571.1    GGFK01006653    MBW39974.1    GGFM01001843    MBW22594.1    GDHC01018898    JAP99730.1    NEDP02001668    OWF52730.1    CH940653    EDW62288.1    OUUW01000025    SPP89629.1    GEZM01012027    GEZM01012021    JAV93273.1    KQ435732    KOX77550.1    CH479209    EDW32710.1    CH379064    EAL31597.3    GAMC01005473    JAC01083.1    CP012528    ALC49896.1    QCYY01000591    ROT84134.1    CH916370    EDW00098.1    GDIP01063696    JAM40019.1    GDIP01217872    JAJ05530.1    GDIP01188920    JAJ34482.1    GDIP01102979    JAM00736.1    AGTO01010573    GDIQ01124217    JAL27509.1    GDIQ01092635    JAL59091.1    GDIQ01121819    JAL29907.1    LRGB01003375    KZS03025.1    GDIQ01039905    JAN54832.1    GDIQ01042599    JAN52138.1    GDIQ01039904    JAN54833.1    JW861536    AFO94053.1    GDIQ01087027    JAN07710.1    GDIQ01087028    JAN07709.1    GDHF01030578    JAI21736.1    GDIP01222166    JAJ01236.1    GDIP01222165    JAJ01237.1    GDHF01017703    JAI34611.1    GDIP01065482    JAM38233.1    GDIQ01148468    JAL03258.1    GG666548    EEN56846.1    KL872975    KGL97368.1    KK733824    KFR00095.1    KK107167    QOIP01000010    EZA56408.1    RLU17601.1    KQ982959    KYQ48773.1    GDIQ01207278    JAK44447.1    KZ506192    PKU40894.1   

Proteomes

UP000007151    UP000037510    UP000027135    UP000192223    UP000235965    UP000183832    + More
UP000007266    UP000008820    UP000069940    UP000249989    UP000245037    UP000075886    UP000009046    UP000030765    UP000007062    UP000000673    UP000069272    UP000095301    UP000075880    UP000242188    UP000008792    UP000268350    UP000053105    UP000008744    UP000001819    UP000005203    UP000092553    UP000283509    UP000001070    UP000016665    UP000076858    UP000095300    UP000001554    UP000053858    UP000053605    UP000053097    UP000279307    UP000075809   

Pfam

PF07819   PGAP1

Interpro

IPR012908   PGAP1-like        + More
IPR039529   PGAP1/BST1       
IPR029058   AB_hydrolase       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

A0A212FP83   A0A2H1VAP4   A0A0L7L106   A0A067QZ37   A0A1W4WDY2   U5EZS7   + More
A0A2J7R6B4   A0A336LRH5   A0A1J1HJN1   A0A1Y1N9E7   A0A1L8DUQ7   A0A1Q3G1I1   A0A1Q3G1J6   D6WW73   A0A1S4FY25   Q16K53   A0A182G874   A0A2P8XLK3   A0A182QD08   E0VHG5   A0A2M4BCT8   A0A2M4BCA0   A0A084VXD6   Q7PSQ5   V5GS79   W5JN50   A0A2M4AGP6   A0A182FLK3   A0A2M3Z242   A0A2M4AGR0   A0A2M3Z263   A0A146KTB8   A0A1I8N7F8   A0A182J144   A0A210QVH4   B4M812   A0A3B0KSD9   A0A1Y1N5V3   A0A0M9A5B9   B4H4F9   Q29I09   A0A088A5S0   W8BQ10   A0A0M4EP13   A0A3R7PVS9   B4JKJ5   A0A0P5Y5F1   A0A0P4Z516   A0A0P5B899   A0A0P5V869   U3JNW4   A0A0P5Q8S3   A0A0N8CCQ3   A0A0N8C2A5   A0A164K7R0   A0A0P6G1F3   A0A0P6HHW7   A0A0P6G852   V9K8G2   A0A1I8PZ32   A0A0P6CUV9   A0A0N8DVT0   A0A0K8U5B9   A0A0P4Z553   A0A0P4YXQ4   A0A0K8V6V2   A0A0P5Y2F6   A0A0P5N884   C3YRU1   A0A0A0AV20   A0A091VBE1   A0A026WKA5   A0A151WLQ7   A0A0P5IVF2   A0A2I0U480  

KEGG

101737839    K05294 GPI inositol-deacylase [EC:3.-.-.-] | (RefSeq) uncharacterized LOC101737839

PATHWAY

00563    Glycosylphosphatidylinositol (GPI)-anchor biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0005789   GO:0016021   GO:0016788   GO:0015031   GO:0006888   GO:0005783   GO:0050185   GO:0006505   GO:0016787   GO:0009880   GO:0021871   GO:0007605   GO:0009948   GO:0003676   GO:0004197   GO:0050790   GO:0006415   GO:0006418   GO:0003723   GO:0046872   GO:0003824  

PANTHER

PTHR15495  

Subcellular location

Endoplasmic reticulum membrane  

Length:

1036

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

139.82153

Exp number, first 60 AAs:

0.00499

Total prob of N-in:

0.00383

outside

1  -  571

TMhelix

572  -  594

inside

595  -  619

TMhelix

620  -  642

outside

643  -  661

TMhelix

662  -  684

inside

685  -  721

TMhelix

722  -  744

outside

745  -  863

TMhelix

864  -  886

inside

887  -  929

TMhelix

930  -  952

outside

953  -  1036

 

 

Pi

256.121717

Theta

21.229776

Tajima's D

1.317998

CLR

0.320071

CSRT

0.749012549372531

Interpretation

Uncertain