Gene

KWMTBOMO10370

Pre Gene Modal

BGIBMGA007060

Annotation

PREDICTED:_evolutionarily_conserved_signaling_intermediate_in_Toll_pathway?_mitochondrial_[Papilio_xuthus]

Location

Bomo_Chr17(+):8883405-8885988      View in EpiBrowser

Full name

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial      

Location in the cell

Cytoplasmic   Reliability : 2.341

CDS

ATGTTTGAAAATCAGGACAACAGAAGAAGAGGACACGTCGAATTTATCTATGCCGCCTTAGCTAGAATGAAGGAATTTGGTGTGCATAAAGACTTACAAGCGTACAAAGCATTAGTAGACGTACTGCCCAAAGGCAAATTTATACCGTCAAATATATTTCAGGCTGAATTCATGCACTATCCGAAGCAACAGCAGTGCGCTGTGGATCTCCTTGAACAGATGGAAGATAATAAAGTAATGCCAGACAGTGAACTAGAGCAAATGTTATTGAACGTTTTTGGAAAAAGAGGCATACCTCTTAGAAAGTTTTGGCGCATGCTGTACTGGATGCCTAAATTCAAGAATCTAAGTCCATGGTATTTACCAGATGAATTGCCGAATGACACATTAGAACTTGCCAAAATGGCTATTCATCGGATAACTTCCGTTGATCCTACTATGAAAATTGAAATTTGGCAGACAGAAGAAATTGAAGCTTGCATAGATAAAACATGGATAGTAAGTGCCCAAAGTGAAACACAAAAGATATTACTCTCAGAGCAACCCCCTGATGAGCCCCTTGTTGTAAGAGGACCTTACGAAGTGTATTTAAAGGAGCAAGTTGTCACTTACTTTACATTATTGGGTAAAGTAAGACCAGAACATAAAGATGACTTTGACCAAGATGATGTATCAAATTTAAAGAAACCTTCCGGAATACCTGGTTTTATTGGTCAAACTACATTACCCGTAGTTAAATGTACTGTACATGAGCAGGATGATGGTACAATAGTAGCTGTATGTGCCACAGGTTCATCATCACGAGATTCTTTGTTATCGTGGATAAGATTATTAGAGAAATATGACAATTCAGTTCTATCAAATCTACCAGTGATTTTCACTCTTACTGCACCTAGCAATGACGTTGTAGTACAGGAAACACAGCCAGCTGCCGAAGATGTAAAAAGAGTGCAAAATTAA

Protein

MFENQDNRRRGHVEFIYAALARMKEFGVHKDLQAYKALVDVLPKGKFIPSNIFQAEFMHYPKQQQCAVDLLEQMEDNKVMPDSELEQMLLNVFGKRGIPLRKFWRMLYWMPKFKNLSPWYLPDELPNDTLELAKMAIHRITSVDPTMKIEIWQTEEIEACIDKTWIVSAQSETQKILLSEQPPDEPLVVRGPYEVYLKEQVVTYFTLLGKVRPEHKDDFDQDDVSNLKKPSGIPGFIGQTTLPVVKCTVHEQDDGTIVAVCATGSSSRDSLLSWIRLLEKYDNSVLSNLPVIFTLTAPSNDVVVQETQPAAEDVKRVQN

Description

Involved in the innate immune response. Promotes the production of antibacterial peptides.
Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.

Subunit

Interacts with Traf6.

Similarity

Belongs to the ECSIT family.

Keywords

Complete proteome   Cytoplasm   Immunity   Innate immunity   Mitochondrion   Nucleus   Reference proteome   Transit peptide  

Feature

chain  Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

Uniprot

A0A194PIV7   H9JC15   A0A194QTN2   A0A0L7LNA1   A0A2H1VPY2   A0A2A4JHG0   + More
A0A1E1W383   A0A346RAD4   A0A212F5G8   A0A1E1W3E6   A0A1W4XFH4   A0A1Y1N150   A0A1Y1MVW3   T1IF30   W5JEM5   D6WU07   A0A182KVX2   A0A182FCZ7   A0A023F2Q5   A0A069DSZ5   A0A182ICX4   A0A182UBW7   Q7QI51   A0A182J825   A0A182WRZ5   A0A182NA29   A0A0V0G7N9   A0A182WK42   A0A2M4AU66   A0A182UQ16   A0A2M4ASX8   A0A182LYP6   A0A182JW46   A0A182RQD7   A0A182SRV3   A0A1J1IRF5   A0A182YP07   A0A084VXL8   A0A182QH61   A0A182HD34   B4K710   Q17B53   A0A067QJH9   A0A034VIQ5   A0A1W4V3Y1   A0A2J7QED4   A0A0K8U9F0   B4MC61   A0A1B0G2E3   A0A0A9XBY9   B3NYI6   B0W9N2   B4I491   W8CCK7   B4QXL9   B6IDJ7   Q9U6M0   B4NHG1   A0A1B6C3D7   D3TPK5   B4PVJ6   A0A1A9WPG9   Q297W7   A0A336MM82   A0A1G4P228   B3LWB9   A0A1B6K3M5   A0A3B0JHR2   A0A0M3QXN1   A0A1B6FQ69   A0A1B6I5L3   A0A0P4WDQ0   A0A1A9ZJH5   A0A1I8NE33   A0A097F5U1   A0A1A9XTD6   A0A1B0BZR9   B4JGQ9   U4UCT0   A0A0T6B347   J3JWY6   N6TV89   A0A1I8PEW7   A0A0L0BXT1   A0A1B6HR21   A0A1Q3F8Y8   B4G354   A0A0N8B818   A0A0P5J8T7   A0A0P4WI97   A0A0P5GHQ6   E9HFW4   A0A1D2MR97   A0A2R7WPM6   A0A0P5W4X3   E2APA7   A0A0P5F948   A0A2S2Q7B6   A0A0J7L406   E9ICX0  

Pubmed

26354079    19121390    26227816    29910977    22118469    28004739    + More
20920257    23761445    18362917    19820115    20966253    25474469    26334808    12364791    14747013    17210077    25244985    24438588    26483478    17994087    17510324    24845553    25348373    25401762    24495485    10465784    10731132    12537572    12537569    20353571    17550304    15632085    25315136    24796866    23537049    22516182    26108605    21292972    27289101    20798317    21282665   

EMBL

KQ459603    KPI92983.1    BABH01014674    KQ461155    KPJ08360.1    JTDY01000512    + More
KOB76834.1    ODYU01003725    SOQ42867.1    NWSH01001431    PCG71249.1    GDQN01009611    JAT81443.1    MH200924    AXS59134.1    AGBW02010202    OWR48978.1    GDQN01009554    JAT81500.1    GEZM01020452    JAV89267.1    GEZM01020451    JAV89268.1    ACPB03009564    ADMH02001370    ETN62807.1    KQ971352    EFA07356.1    GBBI01003102    JAC15610.1    GBGD01002053    JAC86836.1    APCN01006058    AAAB01008810    EAA04813.4    GECL01002054    JAP04070.1    GGFK01011024    MBW44345.1    GGFK01010584    MBW43905.1    AXCM01001615    CVRI01000055    CRL01097.1    ATLV01018097    KE525212    KFB42712.1    AXCN02001953    JXUM01005146    KQ560187    KXJ83937.1    CH933806    EDW15297.2    CH477325    EAT43515.1    KK853286    KDR08946.1    GAKP01017514    JAC41438.1    NEVH01015316    PNF26923.1    GDHF01029055    JAI23259.1    CH940656    EDW58682.2    CCAG010003931    GBHO01026090    GBRD01017769    JAG17514.1    JAG48058.1    CH954181    EDV47967.1    DS231865    EDS40351.1    CH480821    EDW55034.1    GAMC01003526    JAC03030.1    CM000364    EDX11805.1    BT050437    ACJ13144.1    AF182511    AE014297    AY070908    CH964272    EDW84637.1    GEDC01029277    JAS08021.1    EZ423357    ADD19633.1    CM000160    EDW97805.1    CM000070    EAL28088.2    UFQT01001591    SSX31090.1    LT626243    SCW25224.1    CH902617    EDV43752.1    GECU01001645    JAT06062.1    OUUW01000005    SPP80243.1    CP012526    ALC46159.1    GECZ01017422    JAS52347.1    GECU01025521    JAS82185.1    GDRN01097353    GDRN01097352    GDRN01097350    JAI59131.1    KF995355    AIT17846.1    JXJN01023274    CH916369    EDV92663.1    KB631330    KB632210    ERL84242.1    ERL90133.1    LJIG01016030    KRT81824.1    BT127754    AEE62716.1    APGK01050708    APGK01057170    KB741277    KB741176    ENN71316.1    ENN73190.1    JRES01001168    KNC24858.1    GECU01030605    JAS77101.1    GFDL01011058    JAV23987.1    CH479179    EDW24249.1    GDIQ01203715    JAK48010.1    GDIQ01209414    JAK42311.1    GDIP01254874    JAI68527.1    GDIQ01246644    JAK05081.1    GL732637    EFX69389.1    LJIJ01000677    ODM95421.1    KK855234    PTY21572.1    GDIP01091506    JAM12209.1    GL441497    EFN64741.1    GDIQ01258268    JAJ93456.1    GGMS01004425    MBY73628.1    LBMM01000921    KMQ97209.1    GL762419    EFZ21583.1   

Proteomes

UP000053268    UP000005204    UP000053240    UP000037510    UP000218220    UP000007151    + More
UP000192223    UP000015103    UP000000673    UP000007266    UP000075882    UP000069272    UP000075840    UP000075902    UP000007062    UP000075880    UP000076407    UP000075884    UP000075920    UP000075903    UP000075883    UP000075881    UP000075900    UP000075901    UP000183832    UP000076408    UP000030765    UP000075886    UP000069940    UP000249989    UP000009192    UP000008820    UP000027135    UP000192221    UP000235965    UP000008792    UP000092444    UP000008711    UP000002320    UP000001292    UP000000304    UP000000803    UP000007798    UP000002282    UP000091820    UP000001819    UP000007801    UP000268350    UP000092553    UP000092445    UP000095301    UP000092443    UP000092460    UP000001070    UP000030742    UP000019118    UP000095300    UP000037069    UP000008744    UP000000305    UP000094527    UP000000311    UP000036403   

PRIDE

H9JC15    B6IDJ7    Q9U6M0   

Pfam

PF06239   ECSIT        + More
PF14784   ECSIT_C
PF13855   LRR_8

Interpro

IPR010418   ECSIT        + More
IPR029342   ECIST_C       
IPR011990   TPR-like_helical_dom_sf       
IPR032675   LRR_dom_sf       
IPR001611   Leu-rich_rpt       
IPR003591   Leu-rich_rpt_typical-subtyp       

Gene 3D

1.25.40.10     3.80.10.10    

ProteinModelPortal

A0A194PIV7   H9JC15   A0A194QTN2   A0A0L7LNA1   A0A2H1VPY2   A0A2A4JHG0   + More
A0A1E1W383   A0A346RAD4   A0A212F5G8   A0A1E1W3E6   A0A1W4XFH4   A0A1Y1N150   A0A1Y1MVW3   T1IF30   W5JEM5   D6WU07   A0A182KVX2   A0A182FCZ7   A0A023F2Q5   A0A069DSZ5   A0A182ICX4   A0A182UBW7   Q7QI51   A0A182J825   A0A182WRZ5   A0A182NA29   A0A0V0G7N9   A0A182WK42   A0A2M4AU66   A0A182UQ16   A0A2M4ASX8   A0A182LYP6   A0A182JW46   A0A182RQD7   A0A182SRV3   A0A1J1IRF5   A0A182YP07   A0A084VXL8   A0A182QH61   A0A182HD34   B4K710   Q17B53   A0A067QJH9   A0A034VIQ5   A0A1W4V3Y1   A0A2J7QED4   A0A0K8U9F0   B4MC61   A0A1B0G2E3   A0A0A9XBY9   B3NYI6   B0W9N2   B4I491   W8CCK7   B4QXL9   B6IDJ7   Q9U6M0   B4NHG1   A0A1B6C3D7   D3TPK5   B4PVJ6   A0A1A9WPG9   Q297W7   A0A336MM82   A0A1G4P228   B3LWB9   A0A1B6K3M5   A0A3B0JHR2   A0A0M3QXN1   A0A1B6FQ69   A0A1B6I5L3   A0A0P4WDQ0   A0A1A9ZJH5   A0A1I8NE33   A0A097F5U1   A0A1A9XTD6   A0A1B0BZR9   B4JGQ9   U4UCT0   A0A0T6B347   J3JWY6   N6TV89   A0A1I8PEW7   A0A0L0BXT1   A0A1B6HR21   A0A1Q3F8Y8   B4G354   A0A0N8B818   A0A0P5J8T7   A0A0P4WI97   A0A0P5GHQ6   E9HFW4   A0A1D2MR97   A0A2R7WPM6   A0A0P5W4X3   E2APA7   A0A0P5F948   A0A2S2Q7B6   A0A0J7L406   E9ICX0  

KEGG

101737126    K04405 evolutionarily conserved signaling intermediate in Toll pathway | (RefSeq) evolutionarily con

GO

GO:0045087   GO:0005634   GO:0005739   GO:0005737   GO:0051341   GO:0016651   GO:0016021  

PANTHER

PTHR13113  

Subcellular location

Cytoplasm  
Nucleus  
Mitochondrion  

Length:

319

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01117

Exp number, first 60 AAs:

0.00114

Total prob of N-in:

0.14909

outside

1  -  319

 

 

Pi

234.78729

Theta

237.813733

Tajima's D

-0.565614

CLR

0

CSRT

0.231588420578971

Interpretation

Uncertain