Gene

KWMTBOMO10347

Annotation

PREDICTED:_phosphatidylinositol_N-acetylglucosaminyltransferase_subunit_Q_isoform_X2_[Papilio_polytes]

Location

Bomo_Chr17(-):7986452-7990594      View in EpiBrowser

Full name

Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q      

Alternative Name

MGpi1p
N-acetylglucosamyl transferase component GPI1
Phosphatidylinositol-glycan biosynthesis class Q protein

Location in the cell

PlasmaMembrane   Reliability : 4.846

CDS

ATGTTAGGAAAATATTTTTCTTACCACGTTCAGCTGTGGTGGCTGTTTTTAGATGTTTCGGGAGAAAAACTTGACTTAATACTACAGGTCTACCGATATGTGGGTTATTTAGGGCTCACGTTTCAAATAGCAGTGATTTCGGATATGATATGCATTGCAACGTTTCATTCATATTGCATCTATGTTTATGCTGCAAGATTGCTTAACATGCAAATATCAGGTCTGATTGCATTGTTGAGACTCTTCGTTGGTCGCAAATACAATCCACTGAGGGGCAGCATAGACTCTTGTGAATATACGAATCAAGAATTATTTGTAGGAACCGTGGCTTTTACAATATTGTTGCTTTTGCTGCCCACAACAGCATTGTATTATATTGTGTTTACACTGTTTAGAATACTATCTCTGGCGCTTCAGTATATATTAGCGCAGCTGATCTACATTATACAAACATTCCCGTTTTATGTGATATCCCTCTGGGTGTTAAAATCGCCAAAAGTAGCAGGAAACGTTTTAATAGAAAGAGTGAATGGTAGAAACTCACCTTTAGTTGTGGAGGTGCAATTGTTGAGCAAATCCTTAACAGATTTGGTAGCCATGTTCAGACCGCCCGTTGAAAAACCGAAAAATCTTGAATGGACCAATCTATTATCCAATGTTCTAGTTGGAAAACAAATTGTATAA

Protein

MLGKYFSYHVQLWWLFLDVSGEKLDLILQVYRYVGYLGLTFQIAVISDMICIATFHSYCIYVYAARLLNMQISGLIALLRLFVGRKYNPLRGSIDSCEYTNQELFVGTVAFTILLLLLPTTALYYIVFTLFRILSLALQYILAQLIYIIQTFPFYVISLWVLKSPKVAGNVLIERVNGRNSPLVVEVQLLSKSLTDLVAMFRPPVEKPKNLEWTNLLSNVLVGKQIV

Catalytic Activity

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(+) + UDP

Subunit

Associates with PIGA, PIGC, PIGH, PIGP and DPM2. The latter is not essential for activity.

Similarity

Belongs to the PIGQ family.

Keywords

Complete proteome   Glycosyltransferase   GPI-anchor biosynthesis   Membrane   Reference proteome   Transferase   Transmembrane   Transmembrane helix  

Feature

chain  Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

Uniprot

A0A1E1WQB3   A0A2A4JUZ3   A0A2H1W2Z0   S4P5J0   A0A067RQR3   A0A2P8ZKY8   + More
A0A2J7QJF5   A0A139WCV9   A0A1B6DJS4   E9IEF2   A0A151ISH5   A0A3L8DUQ1   A0A026X0V2   F4X5R7   A0A158NMC4   A0A2A3EB01   K7JKT6   A0A232EQ93   A0A146LI72   A0A151WVG4   A0A195CCL3   A0A1Y1NFC8   A0A088AMI3   A0A1B6GIT5   E2BHH6   A0A1B6MFZ7   A0A151K1C4   A0A0T6BEY1   A0A0A9XU87   A0A0M9A2C0   A0A151I387   A0A1W4X273   A0A0L7REY8   A0A0P4VKJ1   J9M0C0   A0A154P1J6   A0A0P5HJ97   A0A0P5HN41   A0A0P5TN65   A0A0N8AH51   A0A0P5YWC7   A0A0N8ANI0   A0A0P5DHZ0   A0A0P5E8Y4   R4WDW8   A0A0P6BYU9   A0A1S3K4Q5   A0A0P5PN85   A0A0P5ELU0   A0A0P5LJA2   A0A094LBX6   A0A226NSJ1   T1KNI6   A0A2I4AK31   F7BRH8   A0A091T8R0   A0A384A3F4   A0A340X3E9   A0A341CLC0   A0A341CLA2   A0A384A3P4   A0A091IMH7   A0A091WMW3   S9XHP1   A0A093QS79   A0A091LB83   A0A091M3S6   A0A3Q0D9N3   A0A1S3EST9   A0A093F7G3   A0A091RR99   A0A087QI88   A0A093FK64   A0A2Y9Q3D8   A0A287D5M4   G3HBT3   A0A093LS95   A0A0A0AVC2   Q3TF56   Q9QYT7   A0A091URH0   G1SE00   A0A2Y9PX26   A0A2Y9PY12   A0A091UCQ0   A0A093NBB5   A0A1S3ESW2   A0A091PMS0   A0A286XXY3   S7N043   A0A226MW60   A0A2Y9DEM2   A0A2K6ENX2   A0A091Q3F7   E1BVN7   A0A384CKB0   Q642B8   A0A091NLB8  

EC Number

2.4.1.198

Pubmed

23622113    24845553    29403074    18362917    19820115    21282665    + More
30249741    24508170    21719571    21347285    20075255    28648823    26823975    28004739    20798317    25401762    27129103    23691247    24621616    19892987    23149746    28071753    21804562    10349636    11042159    11076861    11217851    12466851    12040188    16141073    21183079    9729469    10373468    15489334    21993624    15592404    15057822    15632090   

EMBL

GDQN01001890    JAT89164.1    NWSH01000569    PCG75586.1    ODYU01005919    SOQ47316.1    + More
GAIX01005514    JAA87046.1    KK852478    KDR22985.1    PYGN01000026    PSN57164.1    NEVH01013555    PNF28725.1    KQ971363    KYB25715.1    GEDC01011367    JAS25931.1    GL762591    EFZ21036.1    KQ981090    KYN09564.1    QOIP01000004    RLU24006.1    KK107054    EZA61601.1    GL888742    EGI58157.1    ADTU01020384    KZ288313    PBC28366.1    NNAY01002812    OXU20524.1    GDHC01010785    JAQ07844.1    KQ982701    KYQ51900.1    KQ977957    KYM98455.1    GEZM01003860    JAV96521.1    GECZ01007439    JAS62330.1    GL448301    EFN84829.1    GEBQ01005145    JAT34832.1    KQ981175    KYN45294.1    LJIG01001044    KRT85896.1    GBHO01021148    GBHO01021146    GBRD01016970    GBRD01010658    JAG22456.1    JAG22458.1    JAG48857.1    KQ435791    KOX74389.1    KQ976507    KYM82787.1    KQ414608    KOC69379.1    GDKW01000996    JAI55599.1    ABLF02031485    KQ434796    KZC05727.1    GDIQ01226149    JAK25576.1    GDIQ01224996    JAK26729.1    GDIP01125298    JAL78416.1    GDIP01147929    JAJ75473.1    GDIP01065691    GDIQ01044952    LRGB01000687    JAM38024.1    JAN49785.1    KZS16823.1    GDIQ01258419    JAJ93305.1    GDIP01155931    JAJ67471.1    GDIP01146584    JAJ76818.1    AK417929    BAN21144.1    GDIP01012237    JAM91478.1    GDIQ01131689    JAL20037.1    GDIP01157893    JAJ65509.1    GDIQ01170967    JAK80758.1    KL284272    KFZ68275.1    AWGT02000910    OXB70886.1    CAEY01000277    KK440279    KFQ69997.1    KK500657    KFP09537.1    KK735903    KFR16455.1    KB016354    EPY90077.1    KL421925    KFW89205.1    KK745998    KFP40211.1    KK521056    KFP66433.1    KK384261    KFV50151.1    KK930700    KFQ44983.1    KL225618    KFM00942.1    KK629051    KFV54679.1    AGTP01030746    JH000273    EGW04370.1    KK610035    KFW11556.1    KL873367    KGL98504.1    AK163680    AK169284    CH466606    BAE37455.1    BAE41042.1    EDL22475.1    AF030178    AB008895    AB008921    BC014287    BC003917    KL410017    KFQ93281.1    KK428087    KFQ88296.1    KL224601    KFW61476.1    KK662202    KFQ08950.1    AAKN02007386    KE162966    EPQ10274.1    MCFN01000402    OXB59269.1    KK685658    KFQ14455.1    AADN05000376    AC126071    BC081875    CH473948    AAH81875.1    EDM03983.1    KL385218    KFP89684.1   

Proteomes

UP000218220    UP000027135    UP000245037    UP000235965    UP000007266    UP000078492    + More
UP000279307    UP000053097    UP000007755    UP000005205    UP000242457    UP000002358    UP000215335    UP000075809    UP000078542    UP000005203    UP000008237    UP000078541    UP000053105    UP000078540    UP000192223    UP000053825    UP000007819    UP000076502    UP000076858    UP000085678    UP000198419    UP000015104    UP000192220    UP000002281    UP000261681    UP000265300    UP000252040    UP000053119    UP000053605    UP000189706    UP000081671    UP000053286    UP000248483    UP000005215    UP000001075    UP000053858    UP000000589    UP000053283    UP000001811    UP000054081    UP000005447    UP000198323    UP000248480    UP000233160    UP000000539    UP000261680    UP000002494   

PRIDE

Q9QYT7   

Pfam

PF05024   Gpi1        + More
PF10180   DUF2373

Interpro

IPR007720   GlcNAc_Gpi1        + More
IPR019327   DUF2373       

ProteinModelPortal

A0A1E1WQB3   A0A2A4JUZ3   A0A2H1W2Z0   S4P5J0   A0A067RQR3   A0A2P8ZKY8   + More
A0A2J7QJF5   A0A139WCV9   A0A1B6DJS4   E9IEF2   A0A151ISH5   A0A3L8DUQ1   A0A026X0V2   F4X5R7   A0A158NMC4   A0A2A3EB01   K7JKT6   A0A232EQ93   A0A146LI72   A0A151WVG4   A0A195CCL3   A0A1Y1NFC8   A0A088AMI3   A0A1B6GIT5   E2BHH6   A0A1B6MFZ7   A0A151K1C4   A0A0T6BEY1   A0A0A9XU87   A0A0M9A2C0   A0A151I387   A0A1W4X273   A0A0L7REY8   A0A0P4VKJ1   J9M0C0   A0A154P1J6   A0A0P5HJ97   A0A0P5HN41   A0A0P5TN65   A0A0N8AH51   A0A0P5YWC7   A0A0N8ANI0   A0A0P5DHZ0   A0A0P5E8Y4   R4WDW8   A0A0P6BYU9   A0A1S3K4Q5   A0A0P5PN85   A0A0P5ELU0   A0A0P5LJA2   A0A094LBX6   A0A226NSJ1   T1KNI6   A0A2I4AK31   F7BRH8   A0A091T8R0   A0A384A3F4   A0A340X3E9   A0A341CLC0   A0A341CLA2   A0A384A3P4   A0A091IMH7   A0A091WMW3   S9XHP1   A0A093QS79   A0A091LB83   A0A091M3S6   A0A3Q0D9N3   A0A1S3EST9   A0A093F7G3   A0A091RR99   A0A087QI88   A0A093FK64   A0A2Y9Q3D8   A0A287D5M4   G3HBT3   A0A093LS95   A0A0A0AVC2   Q3TF56   Q9QYT7   A0A091URH0   G1SE00   A0A2Y9PX26   A0A2Y9PY12   A0A091UCQ0   A0A093NBB5   A0A1S3ESW2   A0A091PMS0   A0A286XXY3   S7N043   A0A226MW60   A0A2Y9DEM2   A0A2K6ENX2   A0A091Q3F7   E1BVN7   A0A384CKB0   Q642B8   A0A091NLB8  

KEGG

101746707    K03860 phosphatidylinositol N-acetylglucosaminyltransferase subunit Q | (RefSeq) phosphatidylinosito

PATHWAY

00563    Glycosylphosphatidylinositol (GPI)-anchor biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0017176   GO:0006506   GO:0000506   GO:0016757   GO:0005515   GO:0006415   GO:0006418   GO:0003723   GO:0046872   GO:0003824  

PANTHER

PTHR21329  

Subcellular location

Membrane  

Length:

227

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

89.2052600000001

Exp number, first 60 AAs:

22.12574

Total prob of N-in:

0.73814

POSSIBLE N-term signal

sequence

inside

1  -  32

TMhelix

33  -  52

outside

53  -  61

TMhelix

62  -  84

inside

85  -  104

TMhelix

105  -  127

outside

128  -  139

TMhelix

140  -  162

inside

163  -  227

 

 

Pi

132.254533

Theta

150.856395

Tajima's D

-0.413757

CLR

0.099585

CSRT

0.267486625668717

Interpretation

Uncertain