Gene

KWMTBOMO10332

Pre Gene Modal

BGIBMGA007232

Annotation

PREDICTED:_diacylglycerol_kinase_epsilon_isoform_X2_[Amyelois_transitella]

Location

Bomo_Chr17(-):7785175-7799382      View in EpiBrowser

Full name

Diacylglycerol kinase      

Location in the cell

PlasmaMembrane   Reliability : 1.519

CDS

ATGTTGGCTGTAGTTGGATTGTTTTGTGAGTGTTGTGCTGTTAGTGCATGCAAGAAATGCTACAAGACAGTGGATAAGAGATATAAATGTAAACAATTAACTTGGCCTTCTAATAAAATATTTCCTCATCAGTGGGTTGATGTTGGAATTTCAAGAACAGACATTGCTGAAAATAATGATCATAGTGATGATAGTACTAAGAAATATTTTTGTAGCTGGTGCCAAAGAATAAAGTTGTGTAATAATACTAGGGATTTGAAAACTGAGCAATGTGACTTCCATAAATATAGCAATATTATCATTCCACCCACATCAGTACAAATGGAGAAAGGCAATGTTATTAGTATTCAGCCGGTTAATAACAGCAATTGGGAACCTCTGATCATTATTGCAAACAGGAAATCCGGCAGCAACAGGAGTGATGAGATACTTTCATTATTTAGAGGATTACTCAATCCAATTCAGGTGATTGACGTAAGCGTGACCTCCCCTGAAAGTGTGGTGCGGTGGCTCCCTGAGAAATGTCGTGTGTTGGTCGCAGGTGGGGACGGCACCGTTGCTTGGGTACTTAATGCTTTATTCGCTGCGCCGCACATCAAGGCGGCCGTGGCTATCTTCCCTATGGGGACCGGTAATGATCTGTCTCGTGTGCTCGGCTGGGGTCCGGGCTGTCCGTCATACATTGATGCACATTCAATCATTAGCAGCATAAAACAAGCAACAGTTGAACAATTGGACAGATGGAAAATTATTATTAAACCAAAGCGTGGCCGTCTCGGTCGGCGGGCACCGGAGCGTATATTGCACGCTTACAACTATGCGAGTATTGGAGTAGACGCTCAGGTCGCGCTCGACTTCCATCGCGCCAGGACGCAGTTCTTATATCGATACGCAAGCAGGACCCTTAATTACATAGCGTACGTGTTTCTGGGCGTGGGTCGTGCGCTGGACGACGGCGGGTGCGAGGGGCTGGAGCGGCGGGTGCGGTGCTGCGCGGATGGCGTGGCGTTGACCCTGCCGCCGCTGCAGGCTCTGCTCGCACTCAACATACCCTCCTGGGGCGCAGGCGTGCACCTCTGGAGTATGGGAAGTGAAGATGAAGTCGAAGAACAAAGCATGAGCGATGGAAAATTGGAGGTGGTCGGCATTTCGTCTTCATTTCACATTGCAAGACTTCAGTGCGGTCTGGCTGAACCTTATCGTTTCACACAAGCGTCCAATCTCAGAATTGATCTAGAAGGTTCGTGTGCGATGCAAGTGGACGGCGAGCCCTGGATGCAGGGTCCGGCCACTATTTTAGTGGAGCCGGCTGGACAAAGCACCATGCTGAGAGCGAACATAAAAAGATCTGAATGTTAA

Protein

MLAVVGLFCECCAVSACKKCYKTVDKRYKCKQLTWPSNKIFPHQWVDVGISRTDIAENNDHSDDSTKKYFCSWCQRIKLCNNTRDLKTEQCDFHKYSNIIIPPTSVQMEKGNVISIQPVNNSNWEPLIIIANRKSGSNRSDEILSLFRGLLNPIQVIDVSVTSPESVVRWLPEKCRVLVAGGDGTVAWVLNALFAAPHIKAAVAIFPMGTGNDLSRVLGWGPGCPSYIDAHSIISSIKQATVEQLDRWKIIIKPKRGRLGRRAPERILHAYNYASIGVDAQVALDFHRARTQFLYRYASRTLNYIAYVFLGVGRALDDGGCEGLERRVRCCADGVALTLPPLQALLALNIPSWGAGVHLWSMGSEDEVEEQSMSDGKLEVVGISSSFHIARLQCGLAEPYRFTQASNLRIDLEGSCAMQVDGEPWMQGPATILVEPAGQSTMLRANIKRSEC

Catalytic Activity

a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)

Similarity

Belongs to the eukaryotic diacylglycerol kinase family.

Feature

chain  Diacylglycerol kinase

Uniprot

A0A2H1V771   A0A2A4JRX5   A0A3S2LUW9   A0A194QH30   A0A194QX86   A0A212EIE2   + More
E0VQ75   A0A0L7QK09   A0A195DB38   A0A195AX69   A0A158NLP5   A0A2J7PXH5   K7IWS4   A0A151X811   A0A195C1Y5   A0A232F6G1   F4WXH5   A0A026WJ93   A0A3L8E2R7   A0A1B6C2W1   A0A067QNK5   A0A0T6AYK2   A0A195F593   W5JS06   A0A182FI18   A0A154P9Q0   A0A1B0CE52   A0A1I8NPY8   A0A2P8Y5R9   B3NRV5   A0A0K8VXW9   A0A3B0J0D0   A0A224XMK3   B4P4Y9   A0A1W4VPT5   A0A034WSQ1   A0A1I8N1X9   B3MG14   A0A139WDJ5   A0A0A1WG30   B4KQ02   W8BTH7   B4J883   A0A1A9V247   A0A146M925   F3YD90   B4MDU6   B4HPP2   Q7K579   A0A182WI69   A0A182JDF5   A0A182QQL5   O44334   Q28X81   B4H547   A0A1B0AB78   B4QDG9   A0A1A9X4S0   A0A182PEY2   A0A182SNN6   A0A182K9Y2   E2B3W8   A0A1A9XPJ6   A0A1B0BXA7   A0A182LXJ6   B4N5Z8   A0A182N7J3   A0A0L0C393   A0A2A3E352   A0A182YJI6   Q7PT01   A0A0P4VSY5   A0A0M4EI43   A0A0N0U7D2   E2AH29   A0A171AH78   A0A182R9A4   A0A224YRE2   A0A131YKC7   A0A2R5LDC1   A0A1S4FU05   A0A310SX15   A0A0P5LDM1   A0A182GS87   A0A0N8BG93   E9G1Y7   A0A084WLA8   A0A0P5DYW8   A0A1B6EKU2   A0A0P5W951   A0A1B0D780   A0A0P6IVW4   A0A0K8V5U8   A0A0P5WTH3   B0WPH8   A0A1Q3FDA3   A0A0P4Z6X5   A0A1Y1MA97   A0A131XTD3   Q16PA7  

EC Number

2.7.1.107

Pubmed

26354079    22118469    20566863    21347285    20075255    28648823    + More
21719571    24508170    30249741    24845553    20920257    23761445    29403074    17994087    17550304    25348373    25315136    18362917    19820115    25830018    24495485    26823975    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    11102369    15632085    22936249    20798317    26108605    25244985    12364791    27129103    28797301    26830274    17510324    26483478    21292972    24438588    28004739   

EMBL

ODYU01000787    SOQ36104.1    NWSH01000726    PCG74569.1    RSAL01000198    RVE44539.1    + More
KQ459232    KPJ02751.1    KQ461155    KPJ08186.1    AGBW02014664    OWR41256.1    DS235392    EEB15531.1    KQ414989    KOC58977.1    KQ981042    KYN10103.1    KQ976716    KYM76843.1    ADTU01002188    NEVH01020858    PNF21026.1    AAZX01004127    KQ982431    KYQ56503.1    KQ978344    KYM94857.1    NNAY01000895    OXU26029.1    GL888424    EGI61141.1    KK107218    EZA55164.1    QOIP01000001    RLU26489.1    GEDC01029699    JAS07599.1    KK853134    KDR10864.1    LJIG01022489    KRT80304.1    KQ981805    KYN35628.1    ADMH02000632    ETN65524.1    KQ434850    KZC08572.1    AJWK01008581    AJWK01008582    PYGN01000896    PSN39597.1    CH954179    EDV56257.1    GDHF01008879    JAI43435.1    OUUW01000001    SPP74057.1    GFTR01006604    JAW09822.1    CM000158    EDW90710.1    GAKP01000351    JAC58601.1    CH902619    EDV36709.1    KQ971361    KYB25925.1    GBXI01016949    JAC97342.1    CH933808    EDW08104.1    GAMC01010004    JAB96551.1    CH916367    EDW01220.1    GDHC01002864    JAQ15765.1    BT126251    AEB39612.1    CH940662    EDW58711.1    CH480816    EDW47626.1    AE013599    AY050241    AAF58458.1    AAK84940.1    AXCN02000576    AF017783    AAB97514.1    CM000071    EAL26435.2    CH479210    EDW32883.1    CM000362    CM002911    EDX06834.1    KMY93336.1    GL445407    EFN89637.1    JXJN01022149    AXCM01006814    CH964154    EDW79787.1    JRES01000960    KNC26736.1    KZ288451    PBC25569.1    AAAB01008807    EAA04759.5    GDKW01001506    JAI55089.1    CP012524    ALC40692.1    KQ435711    KOX79421.1    GL439470    EFN67260.1    GEMB01001070    JAS02077.1    GFPF01007183    MAA18329.1    GEDV01010196    JAP78361.1    GGLE01003343    MBY07469.1    KQ759840    OAD62646.1    GDIQ01181713    JAK70012.1    JXUM01016839    KQ560467    KXJ82264.1    GDIQ01180715    JAK71010.1    GL732529    EFX86572.1    ATLV01024210    KE525350    KFB51002.1    GDIP01148944    LRGB01003146    JAJ74458.1    KZS04014.1    GECZ01031215    JAS38554.1    GDIP01102692    JAM01023.1    AJVK01026697    GDIQ01027056    JAN67681.1    GDHF01028579    GDHF01018181    JAI23735.1    JAI34133.1    GDIP01082338    JAM21377.1    DS232024    EDS32366.1    GFDL01009532    JAV25513.1    GDIP01218584    JAJ04818.1    GEZM01036508    JAV82614.1    GEFM01005517    JAP70279.1    CH477789    EAT36194.1   

Proteomes

UP000218220    UP000283053    UP000053268    UP000053240    UP000007151    UP000009046    + More
UP000053825    UP000078492    UP000078540    UP000005205    UP000235965    UP000002358    UP000075809    UP000078542    UP000215335    UP000007755    UP000053097    UP000279307    UP000027135    UP000078541    UP000000673    UP000069272    UP000076502    UP000092461    UP000095300    UP000245037    UP000008711    UP000268350    UP000002282    UP000192221    UP000095301    UP000007801    UP000007266    UP000009192    UP000001070    UP000078200    UP000008792    UP000001292    UP000000803    UP000075920    UP000075880    UP000075886    UP000001819    UP000008744    UP000092445    UP000000304    UP000091820    UP000075885    UP000075901    UP000075881    UP000008237    UP000092443    UP000092460    UP000075883    UP000007798    UP000075884    UP000037069    UP000242457    UP000076408    UP000007062    UP000092553    UP000053105    UP000000311    UP000075900    UP000069940    UP000249989    UP000000305    UP000030765    UP000076858    UP000092462    UP000002320    UP000008820   

PRIDE

F3YD90    Q7K579    O44334   

Pfam

PF00609   DAGK_acc        + More
PF00781   DAGK_cat
PF00130   C1_1
PF00069   Pkinase

Interpro

IPR002110   Ankyrin_rpt        + More
IPR037607   DGK       
IPR016064   NAD/diacylglycerol_kinase_sf       
IPR017438   ATP-NAD_kinase_N       
IPR001206   Diacylglycerol_kinase_cat_dom       
IPR000756   Diacylglycerol_kin_accessory       
IPR020683   Ankyrin_rpt-contain_dom       
IPR036770   Ankyrin_rpt-contain_sf       
IPR002219   PE/DAG-bd       
IPR000719   Prot_kinase_dom       
IPR008271   Ser/Thr_kinase_AS       
IPR011009   Kinase-like_dom_sf       

SUPFAM

SSF111331   SSF111331        + More
SSF48403   SSF48403       
SSF56112   SSF56112       

Gene 3D

1.25.40.20     3.40.50.10330    

CDD

cd00204  ANK
cd00029  C1

ProteinModelPortal

A0A2H1V771   A0A2A4JRX5   A0A3S2LUW9   A0A194QH30   A0A194QX86   A0A212EIE2   + More
E0VQ75   A0A0L7QK09   A0A195DB38   A0A195AX69   A0A158NLP5   A0A2J7PXH5   K7IWS4   A0A151X811   A0A195C1Y5   A0A232F6G1   F4WXH5   A0A026WJ93   A0A3L8E2R7   A0A1B6C2W1   A0A067QNK5   A0A0T6AYK2   A0A195F593   W5JS06   A0A182FI18   A0A154P9Q0   A0A1B0CE52   A0A1I8NPY8   A0A2P8Y5R9   B3NRV5   A0A0K8VXW9   A0A3B0J0D0   A0A224XMK3   B4P4Y9   A0A1W4VPT5   A0A034WSQ1   A0A1I8N1X9   B3MG14   A0A139WDJ5   A0A0A1WG30   B4KQ02   W8BTH7   B4J883   A0A1A9V247   A0A146M925   F3YD90   B4MDU6   B4HPP2   Q7K579   A0A182WI69   A0A182JDF5   A0A182QQL5   O44334   Q28X81   B4H547   A0A1B0AB78   B4QDG9   A0A1A9X4S0   A0A182PEY2   A0A182SNN6   A0A182K9Y2   E2B3W8   A0A1A9XPJ6   A0A1B0BXA7   A0A182LXJ6   B4N5Z8   A0A182N7J3   A0A0L0C393   A0A2A3E352   A0A182YJI6   Q7PT01   A0A0P4VSY5   A0A0M4EI43   A0A0N0U7D2   E2AH29   A0A171AH78   A0A182R9A4   A0A224YRE2   A0A131YKC7   A0A2R5LDC1   A0A1S4FU05   A0A310SX15   A0A0P5LDM1   A0A182GS87   A0A0N8BG93   E9G1Y7   A0A084WLA8   A0A0P5DYW8   A0A1B6EKU2   A0A0P5W951   A0A1B0D780   A0A0P6IVW4   A0A0K8V5U8   A0A0P5WTH3   B0WPH8   A0A1Q3FDA3   A0A0P4Z6X5   A0A1Y1MA97   A0A131XTD3   Q16PA7  

PDB

4WRR     E-value=0.00857556,     Score=93

KEGG

101745335    K00901 diacylglycerol kinase (ATP) [EC:2.7.1.107] | (RefSeq) diacylglycerol kinase epsilon

PATHWAY

00561    Glycerolipid metabolism - Bombyx mori (domestic silkworm)
00564    Glycerophospholipid metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04070    Phosphatidylinositol signaling system - Bombyx mori (domestic silkworm)

GO

GO:0005524   GO:0004143   GO:0003951   GO:0007205   GO:0035556   GO:0016021   GO:0046486   GO:0046834   GO:0046339   GO:0016310   GO:0004672   GO:0016301   GO:0008017   GO:0006811   GO:0006418   GO:0003723   GO:0046872   GO:0003824  

PANTHER

PTHR11255  

Length:

452

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.24136

Exp number, first 60 AAs:

0.00236

Total prob of N-in:

0.00577

outside

1  -  452

 

 

Pi

193.184692

Theta

151.688524

Tajima's D

0.908765

CLR

0.165014

CSRT

0.634768261586921

Interpretation

Uncertain