Gene

KWMTBOMO10308  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007304

Annotation

double-time_protein_[Bombyx_mori]

Location

Bomo_Chr17(+):7328900-7339333      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.185 Mitochondrial   Reliability : 1.523

CDS

ATGGAGCTTCGTGTCGGTAACAAATACCGACTTGGGCGAAAAATTGGCTCCGGATCTTTTGGAGATATATATTTAGGAACAAACATTGTCACAAGGGAAGAAGTAGCCATTAAGTTAGAATGTATCAAAACGAGACATCCACAGTTACACATAGAAAGCAAATTTTACAAACTAATGCAAGGAAGAGTTGGAATTCCTGCAATTAAATGGTGTGGGTCAGAGGGTGACTACAATGTAATGGTAATGGAACTGCTAGGTCCGTCATTGGAAGATCTCTTCAATTTTTGCTCACGTCGTTTTTCTCTCAAGACAGTACTCCTTCTAGCAGACCAACTAATTTCCCGCATTGAGGACATACACTACAGAAATTTTATCCATAGAGACATCAAACCTGACAATTTTCTAATGGGCCTAGGTAAAAAAGGAAATTTAGTGTATATAATAGATTTTGGCTTAGCTAAGAAGTACAAAGATCCTCGGACTAATCAACATATACCTTACAGAGAAAACAAAAATTTGACAGGAACAGCAAGATATGCTTCAATAAATACACATTTAGGAATTGAGCAGTCACGTCGAGATGATCTAGAGTCACTGGGCTATGTGCTCATGTACTTTAACCGTGGTAGTTTACCATGGCAGGGGCTAAAAGCAGCAACAAAACGTCAAAAATATGAAAGAATATCTGAAAAGAAACTGTCCACTCCTTTTGATGAGCTTTGTAAGAACCATCCAATTGAGTTTCAACTGTATTTGAAGTACTGCCGGCGACTTCGTTTCGAGGAGAGACCCGACTACGCCCATCTGCGTCAGTTGTTTCGCACCCTCTTCCACCGGCAAGGATTTACATATGACTACGTGTTTGATTGGAACATGTTAAAGTTTGGAGGACTGCGTGATAACCATCAAACAAGTGGTATTGATCGCGCTCTTAGACGTCTTGAACAAAATCAGGAACAAGAAAATACCGCTGCGACAGCCGGCCAGCCCAGTAATGCAGTGGCAGCAATTTCGGAATGGCGGCTAAGCAGGTTGATAAGTGGGCCGATGAACTCGTAA

Protein

MELRVGNKYRLGRKIGSGSFGDIYLGTNIVTREEVAIKLECIKTRHPQLHIESKFYKLMQGRVGIPAIKWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQLISRIEDIHYRNFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKYKDPRTNQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERISEKKLSTPFDELCKNHPIEFQLYLKYCRRLRFEERPDYAHLRQLFRTLFHRQGFTYDYVFDWNMLKFGGLRDNHQTSGIDRALRRLEQNQEQENTAATAGQPSNAVAAISEWRLSRLISGPMNS

Similarity

Belongs to the protein kinase superfamily.

Uniprot

Q56R81   G0YQM4   A0A2H1WQB2   A0A2A4JEC1   A0A0N6WBX3   H9JCQ7   + More
Q699T6   A0A194QB64   A0A194QX51   S4PFM9   B0LBZ4   A0A212EML0   A0A0L7LCT9   A0A195CU59   A0A026WQT1   A0A1L5YQK0   A0A195BP04   E2ARD2   A0A1Y1KNW0   A0A195FPF0   A0A2P8Y0Z0   A0A154P905   A0A158NTS3   A0A1Y1KL85   A0A069DZ06   A0A224XQ69   A0A151JN46   A0A0P4VNZ2   F4WJ18   E2B5S6   A0A139WD91   A0A1B6M7I5   A0A0L7QPQ4   A0A2P6KS80   T1H831   A0A0K8TK32   A0A0P4WNN0   A0A0A9WZ79   N6UAM1   A0A0P4WUQ2   A0A088ATY4   A0A345AH74   A0A0P4WB54   A0A1D2NGK3   A0A1B6DZB9   A0A226EDT7   V9I6Z6   A0A1B6DH91   A0A1B6CN86   A0A3R7M593   V9I932   A0A1B0YZ26   A0A090XBU6   A0A087U396   A0A1S3JZC2   A0A1B6BZA9   A0A1S3JY89   A0A1S3JYL4   A0A3M0JQ32   F6SZW1   A0A1W5BD19   F6SDI7   A0A1A8BRK2   M7AVG9   A0A1A8RZ10   A0A1A8IQJ5   A0A1A8QWW5   A0A1U7S293   A0A1A8GXK9   A0A1A8UY94   A0A2I6BPZ2   A0A2I0USJ9   A0A218UZU2   K7F8E3   U3J4W3   A0A1V4J9N3   U3KDP9   A0A0Q3M158   H3AHF6   A0A3Q0H9J9   A0A1E1XJT4   A0A336KAA4   A0A226PDP7   A0A2D4H3Z1   H9GDS4   A0A0B8RS38   A0A1W7RIQ0   A0A098LZP6   J3S438   T1E709   A0A3P9PUB2   A0A2D4I9K0   A0A2D4PUI6   V8PFP7   G1NIL4   A0A3Q1EBH8   R0LU56   A0A096LQQ3   A0A224YJ88   L7LYC7  

Pubmed

16998154    19121390    26354079    23622113    18184036    18183285    + More
22118469    26227816    24508170    30249741    20798317    28004739    29403074    21347285    26334808    27129103    21719571    18362917    19820115    25401762    26823975    23537049    27289101    27341138    25970599    26383154    12481130    15114417    23624526    29255161    17381049    23749191    9215903    29209593    24621616    21881562    25476704    26358130    23025625    23758969    25727380    24297900    20838655    28797301    25576852   

EMBL

AY769965    AAX12838.1    HQ731033    AEJ38223.1    ODYU01010271    SOQ55261.1    + More
NWSH01001898    PCG69753.1    KM233159    AKC42320.1    BABH01034710    BABH01034711    AY526606    AAS92607.1    KQ459232    KPJ02783.1    KQ461155    KPJ08151.1    GAIX01003952    JAA88608.1    EF554580    ABU49715.1    AGBW02013813    OWR42709.1    JTDY01001666    KOB73209.1    KQ977279    KYN04062.1    KK107148    QOIP01000009    EZA57459.1    RLU18876.1    KX602319    APP94028.1    KQ976435    KYM87089.1    GL442047    EFN64010.1    GEZM01080417    JAV62151.1    KQ981382    KYN42338.1    PYGN01001065    PSN37932.1    KQ434846    KZC08327.1    ADTU01026123    ADTU01026124    ADTU01026125    GEZM01080416    JAV62152.1    GBGD01001475    JAC87414.1    GFTR01006287    JAW10139.1    KQ978878    KYN27870.1    GDKW01000094    JAI56501.1    GL888181    EGI65788.1    GL445887    EFN88895.1    KQ971361    KYB25815.1    GEBQ01008077    GEBQ01007585    JAT31900.1    JAT32392.1    KQ414806    KOC60617.1    MWRG01006090    PRD29187.1    ACPB03000274    GBRD01000071    GBRD01000069    JAG65750.1    GDRN01057140    JAI65733.1    GBHO01030873    GBHO01030872    GDHC01004029    JAG12731.1    JAG12732.1    JAQ14600.1    APGK01036276    APGK01036277    KB740939    KB632061    ENN77691.1    ERL88420.1    GDRN01057141    JAI65732.1    MF175158    AXF35708.1    GDRN01057143    JAI65730.1    LJIJ01000046    ODN04369.1    GEDC01006265    JAS31033.1    LNIX01000004    OXA55207.1    JR035996    AEY56853.1    GEDC01012254    JAS25044.1    GEDC01022414    GEDC01020197    JAS14884.1    JAS17101.1    QCYY01002802    ROT67534.1    JR035998    AEY56854.1    KX014743    ANO53992.1    GBIH01000219    JAC94491.1    KK117946    KFM71835.1    GEDC01030700    GEDC01029847    JAS06598.1    JAS07451.1    QRBI01000131    RMC03138.1    EAAA01002431    HADZ01005878    SBP69819.1    KB574221    EMP27025.1    HAEI01005375    HAEH01020732    SBS11256.1    HAED01013131    HAEE01016597    SBQ99576.1    HAEF01005195    HAEG01014405    SBR97504.1    HAEB01018596    HAEC01007661    SBQ75799.1    HADY01023452    HAEJ01012099    SBS52556.1    KY923000    AUI80371.1    KZ505643    PKU49035.1    MUZQ01000089    OWK58970.1    AGCU01057925    AGCU01057926    AGCU01057927    AGCU01057928    ADON01047934    ADON01047935    LSYS01008398    OPJ68916.1    AGTO01010190    LMAW01002845    KQK76455.1    AFYH01220118    AFYH01220119    AFYH01220120    AFYH01220121    GFAA01003864    JAT99570.1    UFQS01000037    UFQT01000037    SSW97990.1    SSX18376.1    AWGT02000099    OXB77517.1    IACJ01162687    LAA66688.1    AAWZ02028386    GBSH01000665    JAG68360.1    GDAY02000404    JAV51009.1    GBSI01000554    JAC95942.1    JU174091    GBEX01000582    AFJ49617.1    JAI13978.1    GAAZ01000436    GBKC01000603    JAA97507.1    JAG45467.1    IACK01088356    LAA80893.1    IACN01098536    LAB61627.1    AZIM01000174    ETE72828.1    KB742823    EOB03913.1    AYCK01008215    GFPF01006572    MAA17718.1    GACK01009141    JAA55893.1   

Proteomes

UP000218220    UP000005204    UP000053268    UP000053240    UP000007151    UP000037510    + More
UP000078542    UP000053097    UP000279307    UP000078540    UP000000311    UP000078541    UP000245037    UP000076502    UP000005205    UP000078492    UP000007755    UP000008237    UP000007266    UP000053825    UP000015103    UP000019118    UP000030742    UP000005203    UP000094527    UP000198287    UP000283509    UP000054359    UP000085678    UP000269221    UP000008144    UP000031443    UP000189705    UP000197619    UP000007267    UP000016666    UP000190648    UP000016665    UP000051836    UP000008672    UP000198419    UP000001646    UP000242638    UP000001645    UP000257200    UP000028760   

PRIDE

Q56R81    H9JCQ7   

Pfam

PF00069   Pkinase        + More
PF15882   DUF4735
PF03619   Solute_trans_a

Interpro

IPR017441   Protein_kinase_ATP_BS        + More
IPR011009   Kinase-like_dom_sf       
IPR008271   Ser/Thr_kinase_AS       
IPR000719   Prot_kinase_dom       
IPR031751   DUF4735       
IPR005178   Ostalpha/TMEM184C       

SUPFAM

SSF56112   SSF56112       

ProteinModelPortal

Q56R81   G0YQM4   A0A2H1WQB2   A0A2A4JEC1   A0A0N6WBX3   H9JCQ7   + More
Q699T6   A0A194QB64   A0A194QX51   S4PFM9   B0LBZ4   A0A212EML0   A0A0L7LCT9   A0A195CU59   A0A026WQT1   A0A1L5YQK0   A0A195BP04   E2ARD2   A0A1Y1KNW0   A0A195FPF0   A0A2P8Y0Z0   A0A154P905   A0A158NTS3   A0A1Y1KL85   A0A069DZ06   A0A224XQ69   A0A151JN46   A0A0P4VNZ2   F4WJ18   E2B5S6   A0A139WD91   A0A1B6M7I5   A0A0L7QPQ4   A0A2P6KS80   T1H831   A0A0K8TK32   A0A0P4WNN0   A0A0A9WZ79   N6UAM1   A0A0P4WUQ2   A0A088ATY4   A0A345AH74   A0A0P4WB54   A0A1D2NGK3   A0A1B6DZB9   A0A226EDT7   V9I6Z6   A0A1B6DH91   A0A1B6CN86   A0A3R7M593   V9I932   A0A1B0YZ26   A0A090XBU6   A0A087U396   A0A1S3JZC2   A0A1B6BZA9   A0A1S3JY89   A0A1S3JYL4   A0A3M0JQ32   F6SZW1   A0A1W5BD19   F6SDI7   A0A1A8BRK2   M7AVG9   A0A1A8RZ10   A0A1A8IQJ5   A0A1A8QWW5   A0A1U7S293   A0A1A8GXK9   A0A1A8UY94   A0A2I6BPZ2   A0A2I0USJ9   A0A218UZU2   K7F8E3   U3J4W3   A0A1V4J9N3   U3KDP9   A0A0Q3M158   H3AHF6   A0A3Q0H9J9   A0A1E1XJT4   A0A336KAA4   A0A226PDP7   A0A2D4H3Z1   H9GDS4   A0A0B8RS38   A0A1W7RIQ0   A0A098LZP6   J3S438   T1E709   A0A3P9PUB2   A0A2D4I9K0   A0A2D4PUI6   V8PFP7   G1NIL4   A0A3Q1EBH8   R0LU56   A0A096LQQ3   A0A224YJ88   L7LYC7  

PDB

4TN6     E-value=1.20718e-155,     Score=1410

KEGG

692728    K08960 casein kinase 1, epsilon [EC:2.7.11.1] | (RefSeq) dbt; double-time protein

PATHWAY

04068    FoxO signaling pathway - Bombyx mori (domestic silkworm)
04310    Wnt signaling pathway - Bombyx mori (domestic silkworm)
04341    Hedgehog signaling pathway - fly - Bombyx mori (domestic silkworm)
04391    Hippo signaling pathway - fly - Bombyx mori (domestic silkworm)
04392    Hippo signaling pathway - multiple species - Bombyx mori (domestic silkworm)
04711    Circadian rhythm - fly - Bombyx mori (domestic silkworm)

GO

GO:0004674   GO:0005524   GO:0004672   GO:0005737   GO:0005634   GO:0018105   GO:0006897   GO:0018107   GO:0090263   GO:0032436   GO:0016021   GO:1990904   GO:1903827   GO:0032922   GO:0034613   GO:0030178   GO:2000052   GO:0042752   GO:0006468   GO:0015935   GO:0004812   GO:0006418   GO:0003723   GO:0046872   GO:0003824  

PANTHER

PTHR23423  

Length:

352

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0179

Exp number, first 60 AAs:

0.00331

Total prob of N-in:

0.04168

outside

1  -  352

 

 

Pi

183.775138

Theta

174.588951

Tajima's D

0.305176

CLR

0.404159

CSRT

0.450227488625569

Interpretation

Uncertain