Silkworm Genome Informatics Database

Gene

KWMTBOMO10237

Annotation

PREDICTED:_uncharacterized_protein_LOC101746849_[Bombyx_mori]

Location

Bomo_Chr17(-):5553321-5557321 View in EpiBrowser

Full name

Glucose-6-phosphate 1-dehydrogenase

Location in the cell

Cytoplasmic Reliability : 2.944

CDS

ATGTCTTCTAACATACAGCAAGAGATCCTATGTATTGAAATGGTTGATACCTTGCTACAATGTCCGCTATTTCAGGGATGCAATCGCGATTTCCTTCAGACGATAGCAGCGAACACCAGAACAATAGTTTTGCCCGACAATGAGATCGTGCAGCACGCTGCAGACATCGGCCGGGACATGTATATCTTGCAGAAGGGTTATTGTGACGTGCTAAATCACGATCGTAAGATAGAAAAAAATATTGGACCCGGTGACCATTTTGGCGTTGTAGAGATGCTCTATGGATTACCAAAGCTTCAAGAAGATGTCGATTTGTTATCGAAAGCAAAATGTTTTGAGGAAGCCAAACCTTTGATTGGACGTCTGGATGTCAAAATTAACAGGATAGCGAGAGAGATAAAGGAAAGTTTCGTGGTTTTGAACGAACCGGACACGAGAGCTCACTATTTGGAGATCTTCAAGAAGTTAGGAGTGATGAGCTTAAATGGCTCATGA

Protein

MSSNIQQEILCIEMVDTLLQCPLFQGCNRDFLQTIAANTRTIVLPDNEIVQHAADIGRDMYILQKGYCDVLNHDRKIEKNIGPGDHFGVVEMLYGLPKLQEDVDLLSKAKCFEEAKPLIGRLDVKINRIAREIKESFVVLNEPDTRAHYLEIFKKLGVMSLNGS

Description

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

Catalytic Activity

D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH

Similarity

Belongs to the glucose-6-phosphate dehydrogenase family.

Uniprot

A0A2A4K7A7 A0A3S2NN00 A0A2H1VR22 A0A194QB84 A0A212FIN9 A0A194QXA9 + More
A0A1W9VGT2 A0A3M6UEY5 A0A2B4SML9 A0A139WMM2 A0A1S3RMP1 A0A0L8HHM9 A0A1S3RMV2 A0A1S3RP51 A0A1V9YRJ4 B3RV15 W5MTF2 A0A369S8A8 A0A060XJM5 A0A3L7MYD8

EC Number

1.1.1.49

Pubmed

26354079 22118469 30382153 18362917 19820115 25527045 + More
18719581 30042472 24755649 30285851

EMBL

NWSH01000075 PCG79906.1 RSAL01000029 RVE51790.1 ODYU01003916 SOQ43269.1 + More
KQ459232 KPJ02722.1 AGBW02008356 OWR53592.1 KQ461155 KPJ08211.1 NBMC01000001 OQY35634.1 RCHS01001698 RMX52129.1 LSMT01000052 PFX30303.1 KQ971312 KYB29220.1 KQ418120 KOF88742.1 JNBS01003271 OQR88394.1 DS985244 EDV25418.1 AHAT01027518 NOWV01000042 RDD43146.1 FR905456 CDQ79437.1 QWOG01000097 RLS25254.1

Proteomes

UP000218220 UP000283053 UP000053268 UP000007151 UP000053240 UP000192647 + More
UP000275408 UP000225706 UP000007266 UP000087266 UP000053454 UP000243217 UP000009022 UP000018468 UP000253843 UP000193380

Pfam

PF00027   cNMP_binding        + More
PF00520   Ion_trans
PF07885   Ion_trans_2
PF08561   Ribosomal_L37
PF00479   G6PD_N
PF02781   G6PD_C

Interpro

IPR018490   cNMP-bd-like        + More
IPR014710   RmlC-like_jellyroll
IPR000595   cNMP-bd_dom
IPR005821   Ion_trans_dom
IPR003938   K_chnl_volt-dep_EAG/ELK/ERG
IPR013099   K_chnl_dom
IPR018488   cNMP-bd_CS
IPR016024   ARM-type_fold
IPR013870   Ribosomal_L37_mit
IPR022674   G6P_DH_NAD-bd
IPR019796   G6P_DH_AS
IPR022675   G6P_DH_C
IPR001282   G6P_DH
IPR036291   NAD(P)-bd_dom_sf

SUPFAM

SSF51206   SSF51206        + More
SSF48371   SSF48371
SSF51735   SSF51735

Gene 3D

2.60.120.10

CDD

cd00038 CAP_ED

ProteinModelPortal

A0A2A4K7A7 A0A3S2NN00 A0A2H1VR22 A0A194QB84 A0A212FIN9 A0A194QXA9 + More
A0A1W9VGT2 A0A3M6UEY5 A0A2B4SML9 A0A139WMM2 A0A1S3RMP1 A0A0L8HHM9 A0A1S3RMV2 A0A1S3RP51 A0A1V9YRJ4 B3RV15 W5MTF2 A0A369S8A8 A0A060XJM5 A0A3L7MYD8

PDB

6CJU E-value=2.38615e-05, Score=109

KEGG

101746849 no KO assigned | (RefSeq) uncharacterized LOC101746849

GO

GO:0016021 GO:0006811 GO:0005249 GO:0008076 GO:0005244 GO:0005267 GO:0034765 GO:0005887 GO:0071805 GO:0042391 GO:1901317 GO:0006006 GO:0006098 GO:0050661 GO:0004345

PANTHER

PTHR23429

Length:

164

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00118

Exp number, first 60 AAs:

0.00118

Total prob of N-in:

0.10654

outside

1 - 164

Pi

260.319426

Theta

193.575393

Tajima's D

1.092163

CLR

0

CSRT

0.684915754212289

Interpretation

Possibly Positive selection

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics